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Results: 30
Development of modelling method selection tool for health services management
Gyuchan T Jun, Zoe Morris, Tillal Eldabi, Paul Harper, Aisha Naseer, Brijesh Patel, John P Clarkson
Sep 08, 2018
BACKGROUND: There is an increasing recognition that modelling and simulation can assist in the process of designing health care policies, strategies and operations. However, the current use is limited and answers to questions...
AI4People
David Danks, Christoph Lütge, Franziska Poszler, Aida Acosta, Gail Gottehrer, Lucian Mihet-Popa, Aisha Naseer
Jan 01, 2021
This paper presents the work of the AI4People-Automotive Committee established to advise more concretely on specific ethical issues that arise from autonomous vehicles (AVs). Practical recommendations for the automotive sector...
Published by: IGI Global Scientific Publishing
Population, Ecological Footprint and the Sustainable Development Goals.
The Anthropocene can be read as being the era when the demand humanity makes on the biosphere's goods and services-humanity's 'ecological footprint'-vastly exceeds its ability to supply it on a sustainable basis. Because the...
Genomic instability signals offer diagnostic possibility in early cancer detection
Emerging evidence from the large numbers of cancer genomes analyzed in recent years indicates that chromosomal instability (CI), a well-established hallmark of cancer cells is detectable in precancerous lesions. In this opinion...
Screening for Barrett's Oesophagus
PURPOSE OF REVIEW: The targeted approach adopted for Barrett's oesophagus (BO) screening is sub-optimal considering the large proportion of BO cases that are currently missed. We reviewed the literature highlighting recent...
A Spark-Based Parallel Implementation of Arithmetic Optimization Algorithm
Arithmetic optimization algorithm (AOA) is a recent population-based metaheuristic widely used for solving optimization problems. However, the emerging large-scale optimization problems pose a great challenge for AOA due to its...
Published by: IGI Global Scientific Publishing
Role of amyloid peptides in vascular dysfunction and platelet dysregulation in Alzheimer’s disease
Ilaria Canobbio, Aisha Alsheikh Abubaker, Caterina Visconte, Mauro Torti, Giordano Pula
Mar 03, 2015
Alzheimer’s disease (AD) is the most common neurodegenerative cause of dementia in the elderly. AD is accompanied by the accumulation of amyloid peptides in the brain parenchyma and in the cerebral vessels. The sporadic form...
Role of amyloid peptides in vascular dysfunction and platelet dysregulation in Alzheimer’s disease
Ilaria Canobbio, Aisha Alsheikh Abubaker, Caterina Visconte, Mauro Torti, Giordano Pula
Mar 03, 2015
Alzheimer’s disease (AD) is the most common neurodegenerative cause of dementia in the elderly. AD is accompanied by the accumulation of amyloid peptides in the brain parenchyma and in the cerebral vessels. The sporadic form...
Mtrr hypomorphic mutation alters liver morphology, metabolism and fuel storage in mice.
Alice P Sowton, Nisha Padmanabhan, Simon J Tunster, Ben D McNally, Antonio Murgia, Aisha Yusuf, Julian L Griffin, Andrew J Murray, Erica D Watson
Mar 17, 2020
5-methyl-THF 5-methyltetrahydofolate Agl amylo-alpha-1 6-glucosidase 4-alpha-glucanotransferase gene BCA bicinchoninic acid Bhmt betaine-homocysteine S-methyltransferase gene Ce cholesteryl-ester Cebpa CCAAT/enhancer binding protein (C/EBP) alpha gene Cer ceramide DAG diacylglycerol Ddit3 DNA damage inducible transcript 3 gene ETS electron transport system FCCP p-trifluoromethoxyphenyl hydrazine FFA free fatty acid G6pc glucose 6-phophastase gene Gbe1 glycogen branching enzyme 1 gene Glycogen GSK3 glycogen synthase kinase gene Gyg glycogenin gene Gys2 glycogen synthase 2 gene HOAD 3-hydoxyacyl-CoA dehydrogenase Hepatic fuel storage Isca1 iron‑sulfur cluster assembly 1 gene JO2 oxygen flux LC-MS liquid chromatography-mass spectrometry LPC lysophosphatidylcholine lipidomics Liver metabolism Mitochondrial function MTHFR methylenetetrahydrofolate reductase gene Mtr methionine synthase gene (also MS) MTRR methionine synthase reductase gene (also MSR) Myc myelocytomatosis oncogene NAFLD non-alcoholic fatty liver disease NASH non-alcoholic steatohepatitis Ndufs NADH:ubiquinone oxidoreductase core subunit (ETS complex I) gene OXPHOS oxidative phosphorylation One‑carbon metabolism PA phosphatidic acid PAS periodic acid Schiff PC phosphatidylcholine PE phosphatidylethanolamine PG phosphatidylglycerol PI phosphatidylinositol PIP phosphatidylinositol phosphate(s) PL phospholipid PS phosphatidylserine RIPA Radioimmunoprecipitation assay SAH S-adenosylhomocysteine SAM S-adenosylmethionine SM sphingomyelin TAG triacylglycerol Ugp2 UDP-glucose pyrophophorylase 2 gene gt gene-trap
Fruit Peels
Hidayat Hussain, Nilufar Z Mamadalieva, Amjad Hussain, Uzma Hassan, Aisha Rabnawaz, Ishtiaq Ahmed, Ivan R Green
Jul 09, 2022
Fruits along with vegetables are crucial for a balanced diet. These not only have delicious flavors but are also reported to decrease the risk of contracting various chronic diseases. Fruit by-products are produced in huge...
Fruit Peels
Hidayat Hussain, Nilufar Z Mamadalieva, Amjad Hussain, Uzma Hassan, Aisha Rabnawaz, Ishtiaq Ahmed, Ivan R Green
May 01, 2022
Fruits along with vegetables are crucial for a balanced diet. These not only have delicious flavors but are also reported to decrease the risk of contracting various chronic diseases. Fruit by-products are produced in huge...
Addressing Health Literacy in Patient Decision Aids
Danielle M. Muscat, Jenna Smith, Olivia Mac, Tamara Cadet, Anik Giguere, Ashley J. Housten, Aisha T. Langford, Sian Smith, Marie Anne Durand, Kirsten McCaffery
Oct 01, 2021
Background: There is increasing recognition of the importance of addressing health literacy in patient decision aid (PtDA) development. Purpose: An updated review as part of IPDAS 2.0 examined the extent to which PtDAs are...
Enabling Lifelong Learning in California Community Colleges
Creating flexible pathways for students, especially those who are caregiving, balancing working and learning, and/or acquiring skills and knowledge outside of classrooms, requires coordinated state- and college-level actions....
Higher Education Education Higher Education Social Sciences and Humanities Library and Information Science
Published by: IGI Global Scientific Publishing
Human Bone Marrow Mesenchymal Stromal Cell-Derived CXCL12, IL-6 and GDF-15 and Their Capacity to Support IgG-Secreting Cells in Culture Are Divergently Affected by Doxorubicin
Various subsets of bone marrow mesenchymal stromal cells (BM MSCs), including fibroblasts, endothelial, fat and reticular cells, are implicated in the regulation of the hematopoietic microenvironment and the survival of...
Gintare Lasaviciute, Anna Höbinger, Dorina Ujvari, Daniel Salamon, Aisha Yusuf, Mikael Sundin, Eva Sverremark-Ekström, Rayan Chikhi, Anna Nilsson, Shanie Saghafian-Hedengren
Mar 15, 2021
Hematology Cancer Stem Cell Research - Nonembryonic - Non-Human Stem Cell Research - Nonembryonic - Human Stem Cell Research Pediatric Regenerative Medicine Transplantation 2 Aetiology 5.2 Cellular and gene therapies 5 Development of treatments and therapeutic interventions 2.1 Biological and endogenous factors Cancer Inflammatory and immune system
Mtrr hypomorphic mutation alters liver morphology, metabolism and fuel storage in mice.
Alice P Sowton, Nisha Padmanabhan, Simon J Tunster, Ben D McNally, Antonio Murgia, Aisha Yusuf, Julian L Griffin, Andrew J Murray, Erica D Watson
May 08, 2020
Nonalcoholic fatty liver disease (NAFLD) is associated with dietary folate deficiency and mutations in genes required for one‑carbon metabolism. However, the mechanism through which this occurs is unclear. To improve our...
Published by: Molecular genetics and metabolism reports
Addressing Health Literacy in Patient Decision Aids
Danielle M. Muscat, Jenna Smith, Olivia Mac, Tamara Cadet, Anik Giguere, Ashley J. Housten, Aisha T. Langford, Sian Smith, Marie Anne Durand, Kirsten McCaffery
Oct 01, 2021
Background: There is increasing recognition of the importance of addressing health literacy in patient decision aid (PtDA) development. Purpose: An updated review as part of IPDAS 2.0 examined the extent to which PtDAs are...
Promoting Independence in Dementia (PRIDE)
Aisha Shafayat, Emese Csipke, Lucy Bradshaw, Georgina Charlesworth, Florence Day, Phuong Leung, Esme Moniz-Cook, Alan A Montgomery, Steve Morris, Gail Mountain, Reuben Ogollah, Kirsty Sprange, Lauren Yates, Martin Orrell
Jan 20, 2020
BACKGROUND: Memory services often see people with early stage dementia who are largely independent and able to participate in community activities but who run the risk of reducing activities and social networks. PRIDE is a...
Dementia Feasibility trial self-management Cost-Benefit Analysis Dementia England Feasibility Studies Health Care Costs Healthy lifestyle Humans Independent Living Multicenter Studies as Topic Prospective Studies Randomized Controlled Trials as Topic Self Care Severity of Illness Index Social Behavior Time Factors Treatment Outcome
A Systematic Review and Meta-Analysis of Patient Decision Aids for Socially Disadvantaged Populations
Renata W. Yen, Jenna Smith, Jaclyn Engel, Danielle Marie Muscat, Sian K. Smith, Julien Mancini, Lilisbeth Perestelo-Pérez, Glyn Elwyn, A. James O’Malley, Jo Anna K. Leyenaar, Olivia Mac, Tamara Cadet, Anik Giguere, Ashley J. Housten, Aisha Langford, Kirsten McCaffery, Marie Anne Durand
Oct 31, 2021
BACKGROUND: The effectiveness of patient decision aids (PtDAs) and other shared decision-making (SDM) interventions for socially disadvantaged populations has not been well studied.
PURPOSE: To assess whether PtDAs and...
A Systematic Review and Meta-Analysis of Patient Decision Aids for Socially Disadvantaged Populations
Renata W. Yen, Jenna Smith, Jaclyn Engel, Danielle Marie Muscat, Sian K. Smith, Julien Mancini, Lilisbeth Perestelo-Pérez, Glyn Elwyn, A. James O’Malley, Jo Anna K. Leyenaar, Olivia Mac, Tamara Cadet, Anik Giguere, Ashley J. Housten, Aisha Langford, Kirsten McCaffery, Marie Anne Durand
Oct 31, 2021
BACKGROUND: The effectiveness of patient decision aids (PtDAs) and other shared decision-making (SDM) interventions for socially disadvantaged populations has not been well studied.
PURPOSE: To assess whether PtDAs and...
Social dimensions of fertility behavior and consumption patterns in the Anthropocene.
Scott Barrett, Aisha Dasgupta, Partha Dasgupta, W Neil Adger, John Anderies, Jeroen van den Bergh, Caroline Bledsoe, John Bongaarts, Stephen Carpenter, F Stuart Chapin, Anne-Sophie Crépin, Gretchen Daily, Paul Ehrlich, Carl Folke, Nils Kautsky, Eric F Lambin, Simon A Levin, Karl-Göran Mäler, Rosamond Naylor, Karine Nyborg, Stephen Polasky, Marten Scheffer, Jason Shogren, Peter Søgaard Jørgensen, Brian Walker, James Wilen
Apr 13, 2020
We consider two aspects of the human enterprise that profoundly affect the global environment: population and consumption. We show that fertility and consumption behavior harbor a class of externalities that have not been much...
Personalized Risk Assessment for Prevention and Early Detection of Breast Cancer
Jennifer D Brooks, Hermann H Nabi, Irene L Andrulis, Antonis C Antoniou, Jocelyne Chiquette, Philippe Després, Peter Devilee, Michel Dorval, Arnaud Droit, Douglas F Easton, Andrea Eisen, Laurence Eloy, Samantha Fienberg, David Goldgar, Eric Hahnen, Yann Joly, Bartha Maria Knoppers, Aisha Lofters, Jean-Yves Masson, Nicole Mittmann, Jean-Sébastien Paquette, Nora Pashayan, Rita Schmutzler, Tracy Stockley, Sean V Tavtigian, Meghan J Walker, Michael Wolfson, Anna Maria Chiarelli, Jacques Simard
Aug 02, 2021
Early detection of breast cancer through screening reduces breast cancer mortality. The benefits of screening must also be considered within the context of potential harms (e.g., false positives, overdiagnosis). Furthermore...
Published by: Journal of personalized medicine
Associations between serum 25-hydroxyvitamin D, body mass index and body fat composition among Emirati population
Fatme Alanouti, Amar Sabri Ahmad, Laila Abdel Wareth, Ayesha Al Dhaheri, Abderrahim Oulhaj, Abdulla Al Junaibi, Abdullah Al Naeemi, Aisha Al Hamiz, Ayesha Al Hosani, Eiman Al Zaabi, Fatima Mezhal, Fatma Al Maskari, Habiba Alsafar, Jamila Yaaqoub, Marina Al Bastaki, Mohammed Al Houqani, Naima Oumeziane, Nirmin F Juber, Scott Sherman, Syed M Shah, Teeb Alsharid, Thekra Al Zaabi, Tom Loney, Wael Al Mahmeed, Abdishakur Abdulle, Raghib Ali
Oct 24, 2022
The genotypic and phenotypic spectrum of MTO1 deficiency.
James J O'Byrne, Maja Tarailo-Graovac, Aisha Ghani, Michael Champion, Charu Deshpande, Ali Dursun, Riza K Ozgul, Peter Freisinger, Ian Garber, Tobias B Haack, Rita Horvath, Ivo Barić, Ralf A Husain, Leo AJ Kluijtmans, Urania Kotzaeridou, Andrew A Morris, Colin J Ross, Saikat Santra, Jan Smeitink, Mark Tarnopolsky, Saskia B Wortmann, Johannes A Mayr, Michaela Brunner-Krainz, Holger Prokisch, Wyeth W Wasserman, Ron A Wevers, Udo F Engelke, Richard J Rodenburg, Teck Wah Ting, Robert McFarland, Robert W Taylor, Ramona Salvarinova, Clara DM van Karnebeek
Mar 07, 2019
BACKGROUND: Mitochondrial diseases, a group of multi-systemic disorders often characterized by tissue-specific phenotypes, are usually progressive and fatal disorders resulting from defects in oxidative phosphorylation. MTO1...
Cardiomyopathy ketogenic diet lactic acidosis mitochondrial disease Mitochondrial translation optimization 1 Oxidative Phosphorylation Defect Adolescent Biopsy Brain Cardiomyopathy Hypertrophic Carrier Proteins Child Child Preschool Female Frameshift Mutation Hepatic encephalopathy Humans Infant Infant Newborn Male metabolism Inborn Errors Mitochondrial Diseases Oxidative Phosphorylation RNA-Binding Proteins
Associations between serum 25-hydroxyvitamin D, body mass index and body fat composition among Emirati population
Fatme Alanouti, Amar Sabri Ahmad, Laila Abdel Wareth, Ayesha Al Dhaheri, Abderrahim Oulhaj, Abdulla Al Junaibi, Abdullah Al Naeemi, Aisha Al Hamiz, Ayesha Al Hosani, Eiman Al Zaabi, Fatima Mezhal, Fatma Al Maskari, Habiba Alsafar, Jamila Yaaqoub, Marina Al Bastaki, Mohammed Al Houqani, Naima Oumeziane, Nirmin F Juber, Scott Sherman, Syed M Shah, Teeb Alsharid, Thekra Al Zaabi, Tom Loney, Wael Al Mahmeed, Abdishakur Abdulle, Raghib Ali
Nov 27, 2022
INTRODUCTION: Vitamin D deficiency and insufficiency are highly prevalent among several populations across the globe. Numerous studies have shown a significant correlation between body-mass-index (BMI) and Vitamin D status...
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