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Immune cells process a myriad of biochemical signals but their function and behavior are also determined by mechanical cues. Macrophages are no exception to this. Being present in all types of tissues, macrophages are exposed to...

Cell and Developmental Biology innate immunity MACROPHAGES mechanosensing substrate stiffness NLRP3 inflammasome ASC actomyosin contractility

Immune cells process a myriad of biochemical signals but their function and behavior are also determined by mechanical cues. Macrophages are no exception to this. Being present in all types of tissues, macrophages are exposed to...

ASC NLRP3 inflammasome actomyosin contractility innate immunity MACROPHAGES mechanosensing substrate stiffness

BACKGROUND: Traffic-related air pollution (TRAP) refers to the wide range of air pollutants emitted by traffic that are dispersed into the ambient air. Emerging evidence shows that TRAP can increase asthma incidence in children....

Air Pollution Asthma Cost of Illness Economics pediatric asthma Public Health traffic emissions traffic related air pollution Air Pollutants Air Pollution Asthma Child Environmental Exposure Humans Nitrogen Dioxide Traffic-Related Pollution United States

Background: Traffic-related air pollution (TRAP) refers to the wide range of air pollutants emitted by traffic that are dispersed into the ambient air. Emerging evidence shows that TRAP can increase asthma incidence in children....

Air Pollution Asthma Cost of Illness traffic emissions Public Health Economics pediatric asthma traffic related air pollution

UVA treatment of cultured human skin fibroblasts (FEK4) has been shown previously to reduce transcriptional activation of heme oxygenase 1 (HO-1) following a second dose of UVA radiation, a phenomenon known as refractoriness....

UVA treatment of cultured human skin fibroblasts (FEK4) has been shown previously to reduce transcriptional activation of heme oxygenase 1 (HO-1) following a second dose of UVA radiation, a phenomenon known as refractoriness....

Solar UVA irradiation-generated reactive oxygen species (ROS) induces the expression of matrix metalloproteinase 1 (MMP-1), leading to photoaging, however the molecular mechanism remains unclear. In the present study, we...

Anti-photoaging COL-1 Eriodictyol MAPK MMP-1 ROS TIMP-1 UVA /dk/atira/pure/subjectarea/asjc/3100/3108 name=Radiation /dk/atira/pure/subjectarea/asjc/3600/3614 name=Radiological and Ultrasound Technology /dk/atira/pure/subjectarea/asjc/1300/1304 name=Biophysics /dk/atira/pure/subjectarea/asjc/2700/2741 name=Radiology Nuclear Medicine and imaging

Solar UVA irradiation-generated reactive oxygen species (ROS) induces the expression of matrix metalloproteinase 1 (MMP-1), leading to photoaging, however the molecular mechanism remains unclear. In the present study, we...

Anti-photoaging COL-1 Eriodictyol MAPK MMP-1 ROS TIMP-1 UVA /dk/atira/pure/subjectarea/asjc/3100/3108 name=Radiation /dk/atira/pure/subjectarea/asjc/3600/3614 name=Radiological and Ultrasound Technology /dk/atira/pure/subjectarea/asjc/1300/1304 name=Biophysics /dk/atira/pure/subjectarea/asjc/2700/2741 name=Radiology Nuclear Medicine and imaging