Search

Results: 1180
Coupling Computational and Intracellular Screening and Selection Toward Co-compatible cJun and cFos Antagonists
Basic leucine-zipper (bZIP) proteins represent difficult yet compelling oncogenic targets, since numerous cell-signalling cascades converge upon them where they function to modulate transcription of specific gene targets. bZIPs...
Published by:
Coupling Computational and Intracellular Screening and Selection Toward Co-compatible cJun and cFos Antagonists
Basic leucine-zipper (bZIP) proteins represent difficult yet compelling oncogenic targets, since numerous cell-signalling cascades converge upon them where they function to modulate transcription of specific gene targets. bZIPs...
Published by:
Corrections to: Use of the BOADICEA Web Application in clinical practice
The article "Use of the BOADICEA Web Application in clinical practice: appraisals by clinicians from various countries" written by Anne Brédart · Jean‑Luc Kop · Antonis C. Antoniou · Alex P. Cunningham · Antoine De Pauw ·Marc...
Published by:
Combining Constrained Heptapeptide Cassettes With Computational Design to Create Coiled-coil Targeting Helical Peptides

A total of 32 heptapeptides have been synthesized and characterized to establish the effect of K → D (i → i + 4) lactamization upon their ability to adopt a helical conformation. Because most parallel and dimeric coiled-coil...

Published by:
Associative Patterning
This chapter begins with a brief discussion of the basic concepts related to the unconscious life of an organization, and then addresses specific aspects of knowledge, learning, and memory, developing a language and framework...
Computational Competitive and Negative Design to Derive a Specific cJun Antagonist

Basic leucine zipper (bZIP) proteins reside at the end of cell-signaling cascades and function to modulate transcription of specific gene targets. bZIPs are recognized as important regulators of cellular processes such as...

Published by:
Combining Constrained Heptapeptide Cassettes With Computational Design to Create Coiled-coil Targeting Helical Peptides

A total of 32 heptapeptides have been synthesized and characterized to establish the effect of K → D (i → i + 4) lactamization upon their ability to adopt a helical conformation. Because most parallel and dimeric coiled-coil...

Published by:
Leaders, Decisions, and the Neuro-Knowledge System
Every decision-maker has a self-organizing, hierarchical set of theories (and consistent relationship among those theories) that guide their decision-making process. In support of this thesis the authors explore the following...
Computational Competitive and Negative Design to Derive a Specific cJun Antagonist

Basic leucine zipper (bZIP) proteins reside at the end of cell-signaling cascades and function to modulate transcription of specific gene targets. bZIPs are recognized as important regulators of cellular processes such as...

Published by:
Modeling the Complexity of Road Accidents Prevention
Simplistic representations of traffic safety disregard the dynamic interactions between the components of the road transport system (RTS). The resultant road accident (RA) preventive measures are consequently focused almost...
Computational prediction and design for creating iteratively larger heterospecific coiled coil sets
A major biochemical goal is the ability to mimic nature in engineering highly specific protein-protein interactions. We previously devised a computational interactome screen to identify eight peptides that form four...
Published by:
Developing Critical Digital Literacies Through Digital Storytelling
The South African Higher Education sector has undergone major transformation since the end of Apartheid more than 25 years ago. Critical digital literacies and critical (digital) citizenship, aligns with the most important...
Computational prediction and design for creating iteratively larger heterospecific coiled coil sets
A major biochemical goal is the ability to mimic nature in engineering highly specific protein-protein interactions. We previously devised a computational interactome screen to identify eight peptides that form four...
Published by:
Unveiling the Triagonal Dynamics of Absorptive Capacity 4.0
This study delves into the intricate relationship between Absorptive Capacity, Organizational Learning, and the Learning Organization. It introduces Absorptive Capacity 4.0, a dynamic framework that traces an organization's...
New CSL President, Vice President Vow to 'Mobilize' Student Government
Winthrop University
Jan 01, 0001
The two ran on a platform that promised to make CSL more inclusive and accessible to the student body by "mobilizing it and bringing it to [their] fellow Eagles." The Winthrop University student body elected Ray McKetty and...
Published by: Winthrop University
Social Learning from the Inside Out
This chapter explores from the viewpoint of the mind/brain the factors and conditions which influence the social creation and sharing of knowledge. A foundation is developed by providing clear definitions of information...
AI Is Transforming Insurance With Five Emerging Business Models
Artificial intelligence and related technologies are creating new opportunities and challenges for organizations across the insurance value chain. Incumbents are adopting AI-driven automation at different speeds, and new...
The Grizzly, October 13, 2022
Meet Arthur Artene, Student Government President Petite Filet in my Wismer? More Likely Than You Think A Note From the Editor Dr. Len Lawson, Award-Winning Poet and Scholar Alex Peay '09 and Rising Up Opinions: Plans for...
Published by: Ursinus College
The Grizzly, April 23, 2020
Keeping up in the Quarantine The Career and Post-Graduate Development Office Adjusts to Online Campus New UCSG President Elected Student Literary Magazine, The Lantern, Launches Online Tiger King and the Spectacle of the...
Published by: Ursinus College
Seeking Global Coherence
Alex Bennet
Feb 11, 2022
The historical focus on relationships based on the trust and respect of people—initially family and then moving into business associates—has become idea focused, with value built on respect for and resonance with ideas....

|<

<

1

2

3

4

5

>

>|