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Myosin VI and optineurin are required for polarized EGFR delivery and directed migration.
The polarized trafficking of membrane proteins into the leading edge of the cell is an integral requirement for cell migration. Myosin VI and its interacting protein optineurin have previously been shown to operate in...
Carbon neutral manufacturing via on-site CO2 recycling.
The chemical industry needs to significantly decrease carbon dioxide (CO2) emissions in order to meet the 2050 carbon neutrality goal. Utilization of CO2 as a chemical feedstock for bulk products is a promising way to mitigate...
Efficient Syntheses of Biobased Terephthalic Acid, p-Toluic Acid and p-Methylacetophenone via One-Pot Catalytic Aerobic Oxidation of Monoterpene Derived bio-p-Cymene
An efficient elevated-pressure catalytic oxidative process (2.5 mol % Co(NO3)2, 2.5 mol % MnBr2, air (30 bar), 125 °C, acetic acid, 6 h) has been developed to oxidize p-cymene into crystalline white terephthalic acid (TA) in...
Bio- p-cymene Bio- p-methylacetophenone Bio- p-toluic acid Bio-terephthalic acid Catalytic aerobic oxidation Terpene biorefinery /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/2300/2304 name=Environmental Chemistry /dk/atira/pure/subjectarea/asjc/1500/1500 name=General Chemical Engineering /dk/atira/pure/subjectarea/asjc/2100/2105 name=Renewable Energy, Sustainability and the Environment /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy
Quantitative In Silico Prediction of the Rate of Protodeboronation by a Mechanistic Density Functional Theory-Aided Algorithm.
Computational reaction prediction has become a ubiquitous task in chemistry due to the potential value accurate predictions can bring to chemists. Boronic acids are widely used in industry; however, understanding how to avoid...
Efficient Syntheses of Biobased Terephthalic Acid, p-Toluic Acid, and p-Methylacetophenone via One-Pot Catalytic Aerobic Oxidation of Monoterpene Derived Bio-p-cymene.
An efficient elevated-pressure catalytic oxidative process (2.5 mol % Co(NO3)2, 2.5 mol % MnBr2, air (30 bar), 125 °C, acetic acid, 6 h) has been developed to oxidize p-cymene into crystalline white terephthalic acid (TA) in...
Multivariate data analysis and metabolic profiling of artemisinin and related compounds in high yielding varieties of Artemisia annua field-grown in Madagascar.
Human MicroRNA targets.
MicroRNAs (miRNAs) interact with target mRNAs at specific sites to induce cleavage of the message or inhibit translation. The specific function of most mammalian miRNAs is unknown. We have predicted target sites on the 3'...
3' Untranslated Regions Algorithms Amino Acid Motifs Amyloid beta-Protein Precursor Animals Chromosome Mapping Computational Biology Conserved Sequence DNA Complementary Disks Large Homolog 4 Protein Fragile X Mental Retardation Protein Gene Expression Regulation Gene Silencing Humans Intracellular Signaling Peptides and Proteins Introns Membrane Proteins MicroRNAs Models Genetic Models Statistical Molecular Sequence Data Polyadenylation Protein Binding Protein Biosynthesis Protein Structure Tertiary RNA RNA Messenger Rats Software
Amino acid dependent formaldehyde metabolism in mammals
Matthias Pietzke, Guillermo Burgos-Barragan, Niek Wit, Jacqueline Tait-Mulder, David Sumpton, Gillian M. Mackay, Ketan J. Patel, Alexei Vazquez
Feb 18, 2021
Abstract: Aldehyde dehydrogenase class 3, encoded by ADH5 in humans, catalyzes the glutathione dependent detoxification of formaldehyde. Here we show that ADH5 deficient cells turn over formaldehyde using alternative pathways...
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