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Influenza virus-infected dendritic cells stimulate strong proliferative and cytolytic responses from human CD8+ T cells
Bhardwaj, N., Bender, A., Gonzalez, N., Bui, L.K., Garrett, M.C., and Steinman, R.M. Influenza virus-infected dendritic cells stimulate strong proliferative and cytolytic responses from human CD8+ T cells. J. Clin. Invest. 94...
Published by: The American Society for Clinical Investigation
Membrane Interactions and Toxicity by Misfolded Protein Oligomers.
The conversion of otherwise soluble proteins into insoluble amyloid aggregates is associated with a range of neurodegenerative disorders, including Alzheimer's and Parkinson's diseases, as well as non-neuropathic conditions such...
Using self-adaptive optimisation methods to perform sequential optimisation for low-energy building design
The use of software tools to aid building design, or to show compliance, is now commonplace. This has motivated investigations into the potential of optimisation algorithms, used in such software, to automatically optimise...
Lumped parameter models for building thermal modelling
There are many sophisticated building simulators capable of accurately modelling the thermal performance of buildings. Lumped Parameter Models (LPMs) are an alternative which, due to their shorter computational time, can be used...
Using self-adaptive optimisation methods to perform sequential optimisation for low-energy building design
The use of software tools to aid building design, or to show compliance, is now commonplace. This has motivated investigations into the potential of optimisation algorithms, used in such software, to automatically optimise...
The practical optimisation of complex architectural forms
The energy consumption of a building and its internal conditions are intimately related to its shape. There have been various attempts to use computer-based optimisation within a thermal simulation environment to produce designs...
Lumped parameter models for building thermal modelling
There are many sophisticated building simulators capable of accurately modelling the thermal performance of buildings. Lumped Parameter Models (LPMs) are an alternative which, due to their shorter computational time, can be used...
The practical optimisation of complex architectural forms
The energy consumption of a building and its internal conditions are intimately related to its shape. There have been various attempts to use computer-based optimisation within a thermal simulation environment to produce designs...
High resolution mapping of overheating and mortality risk
Chunde Liu, Tristan Kershaw, Daniel Fosas, Alfonso Ramallo Gonzalez, Sukumar Natarajan, David Coley
Sep 01, 2017
Both the Paris heat wave of 2003 and recent high-resolution climate change predictions indicate a world where mortality from extreme weather events will increase. Most heat wave deaths occur in buildings, and are driven by the...
High resolution mapping of overheating and mortality risk
Chunde Liu, Tristan Kershaw, Daniel Fosas, Alfonso Ramallo Gonzalez, Sukumar Natarajan, David Coley
Sep 01, 2017
Both the Paris heat wave of 2003 and recent high-resolution climate change predictions indicate a world where mortality from extreme weather events will increase. Most heat wave deaths occur in buildings, and are driven by the...
Exogenous glucose oxidation during exercise is positively related to body size
Abdullah Ijaz, Adam Collins, Alfonso Moreno-Cabañas, Louise Bradshaw, Katie Hutchins, Tim Podlogar, Gareth A Wallis, Javier Gonzalez
Sep 27, 2024
There is little evidence that body size alters exogenous glucose oxidation rates during exercise. This study assessed whether larger people oxidize more exogenous glucose during exercise than smaller people. Fifteen cyclists...
Overheating in vulnerable and non-vulnerable households
Marika Vellei, Alfonso P. Ramallo Gonzalez, David Coley, Jeehang Lee, Elizabeth Gabe-Thomas, Thomas Lovett, Sukumar Natarajan
Jan 01, 0001
As the 2003 European heatwave demonstrated, overheating in homes can cause wide-scale fatalities. With temperatures and heatwave frequency predicted to increase due to climate change, such events can be expected to become more...
A Review of Current and Future Weather Data for Building Simulation
Manuel Herrera, Sukumar Natarajan, David Coley, Tristan Kershaw, Alfonso P Ramallo Gonzalez, Matthew Eames, Daniel Fosas, Michael Wood
Sep 01, 2017
This article provides the first comprehensive assessment of methods for the creation of weather variables for use in building simulation. We undertake a critical analysis of the fundamental issues and limitations of each...
Exogenous glucose oxidation during exercise is positively related to body size
Abdullah Ijaz, Adam Collins, Alfonso Moreno-Cabañas, Louise Bradshaw, Katie Hutchins, Tim Podlogar, Gareth A Wallis, Javier Gonzalez
Sep 27, 2024
There is little evidence that body size alters exogenous glucose oxidation rates during exercise. This study assessed whether larger people oxidize more exogenous glucose during exercise than smaller people. Fifteen cyclists...
Overheating in vulnerable and non-vulnerable households
Marika Vellei, Alfonso P. Ramallo Gonzalez, David Coley, Jeehang Lee, Elizabeth Gabe-Thomas, Thomas Lovett, Sukumar Natarajan
Jan 01, 0001
As the 2003 European heatwave demonstrated, overheating in homes can cause wide-scale fatalities. With temperatures and heatwave frequency predicted to increase due to climate change, such events can be expected to become more...
A Review of Current and Future Weather Data for Building Simulation
Manuel Herrera, Sukumar Natarajan, David Coley, Tristan Kershaw, Alfonso P Ramallo Gonzalez, Matthew Eames, Daniel Fosas, Michael Wood
Sep 01, 2017
This article provides the first comprehensive assessment of methods for the creation of weather variables for use in building simulation. We undertake a critical analysis of the fundamental issues and limitations of each...
Sign-Inverting Vectors Underlie a Coordinate Transformation in the Drosophila Central Brain
Itzel Gonzalez Ishida
Jan 01, 0001
Our coherent sense of orientation is built from combining sensory experiences across different modalities. How animal brains compute and remember the directions of motion of the body, limbs, objects or landmarks in a shared...
Published by: Rockefeller University
Sex-specific associations of basal steroid hormones and neuropeptides with Conduct Disorder and neuroendocrine mediation of environmental risk
Anka Bernhard, Marietta Kirchner, Anne Martinelli, Katharina Ackermann, Gregor Kohls, Karen Gonzalez-Madruga, Amy Wells, Aranzazu Fernández-Rivas, Maider Gonzalez De Artaza-Lavesa, Nora Maria Raschle, Angeliki Konsta, Réka Siklósi, Amaia Hervás, Beate Herpertz-Dahlmann, Stephane A. De Brito, Arne Popma, Christina Stadler, Kerstin Konrad, Graeme Fairchild, Christine M. Freitag
Aug 31, 2021
Conduct Disorder (CD) is characterized by severe aggressive and antisocial behavior. The stress hormone system has frequently been investigated as a neurobiological correlate of CD, while other interacting neuroendocrine...
Conduct Disorder Environmental risk factors FEMNAT-CD Neuropeptides Sex differences Steroid hormones /dk/atira/pure/subjectarea/asjc/3000/3004 name=Pharmacology /dk/atira/pure/subjectarea/asjc/2800/2808 name=Neurology /dk/atira/pure/subjectarea/asjc/2700/2728 name=Clinical Neurology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/subjectarea/asjc/2800/2803 name=Biological Psychiatry /dk/atira/pure/subjectarea/asjc/2700/2736 name=Pharmacology (medical) /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Sex-specific associations of basal steroid hormones and neuropeptides with Conduct Disorder and neuroendocrine mediation of environmental risk
Anka Bernhard, Marietta Kirchner, Anne Martinelli, Katharina Ackermann, Gregor Kohls, Karen Gonzalez-Madruga, Amy Wells, Aranzazu Fernández-Rivas, Maider Gonzalez De Artaza-Lavesa, Nora Maria Raschle, Angeliki Konsta, Réka Siklósi, Amaia Hervás, Beate Herpertz-Dahlmann, Stephane A. De Brito, Arne Popma, Christina Stadler, Kerstin Konrad, Graeme Fairchild, Christine M. Freitag
Aug 31, 2021
Conduct Disorder (CD) is characterized by severe aggressive and antisocial behavior. The stress hormone system has frequently been investigated as a neurobiological correlate of CD, while other interacting neuroendocrine...
Conduct Disorder Environmental risk factors FEMNAT-CD Neuropeptides Sex differences Steroid hormones /dk/atira/pure/subjectarea/asjc/3000/3004 name=Pharmacology /dk/atira/pure/subjectarea/asjc/2800/2808 name=Neurology /dk/atira/pure/subjectarea/asjc/2700/2728 name=Clinical Neurology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/subjectarea/asjc/2800/2803 name=Biological Psychiatry /dk/atira/pure/subjectarea/asjc/2700/2736 name=Pharmacology (medical) /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Facial geometry parameterisation based on Partial Differential Equations
Geometric modelling using Partial Differential Equations (PDEs) has been gradually recognised due to its smooth instinct, as well as the ability to generate a variety of geometric shapes by intuitively manipulating a relatively...
On the nature and function of organizers.
Organizers, which comprise groups of cells with the ability to instruct adjacent cells into specific states, represent a key principle in developmental biology. The concept was first introduced by Spemann and Mangold, who showed...
Multi-Class Cost-Constrained Random Coding for Correlated Sources over the Multiple-Access Channel.
This paper studies a generalized version of multi-class cost-constrained random-coding ensemble with multiple auxiliary costs for the transmission of N correlated sources over an N-user multiple-access channel. For...
Wnt/ß-catenin signalling and the dynamics of fate decisions in early mouse embryos and embryonic stem (ES) cells
tWnt/ß-catenin signalling is a widespread cell signalling pathway with multiple roles during vertebrate development. In mouse embryonic stem (mES) cells, there is a dual role for ß-catenin: it promotes differentiation when...
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