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Results: 401
Genome-wide DNA methylation dynamics during epigenetic reprogramming in the porcine germline.
Isabel Gómez-Redondo, Benjamín Planells, Sebastián Cánovas, Elena Ivanova, Gavin Kelsey, Alfonso Gutiérrez-Adán
Feb 04, 2021
BACKGROUND: Prior work in mice has shown that some retrotransposed elements remain substantially methylated during DNA methylation reprogramming of germ cells. In the pig, however, information about this process is scarce. The...
Embryo Methylation reprogramming primordial germ cells Whole-genome bisulphite sequencing Animals Blastocyst Cellular Reprogramming DNA Methylation Epigenomics Female Fetus Genome-Wide Association Study Genomic Imprinting Germ Cells Humans Introns Long Interspersed Nucleotide Elements Male Mice Short Interspersed Nucleotide Elements Swine Terminal Repeat Sequences whole genome sequencing
Ante rem structuralism and the semantics of instantial terms
Sofía Meléndez Gutiérrez
Oct 24, 2022
Abstract: Ante rem structures were posited as the subject matter of mathematics in order to resolve a problem of referential indeterminacy within mathematical discourse. Nevertheless, ante rem structuralists are inevitably...
Original Research Mathematical structuralism Ante rem structuralism Referential indeterminacy Instantial terms Instantial reasoning
Published by: Springer Netherlands
Ante rem structuralism and the semantics of instantial terms
Abstract Ante rem structures were posited as the subject matter of mathematics in order to resolve a problem of referential indeterminacy within mathematical discourse....
Sofía Meléndez Gutiérrez
Oct 10, 2022
A gene catalogue of the amphioxus nervous system.
Elia Benito-Gutiérrez
Sep 05, 2018
The elaboration of extremely complex nervous systems is a major success of evolution. However, at the dawn of the post-genomic era, few data have helped yet to unravel how a nervous system develops and evolves to complexity. On...
Membrane Interactions and Toxicity by Misfolded Protein Oligomers.
The conversion of otherwise soluble proteins into insoluble amyloid aggregates is associated with a range of neurodegenerative disorders, including Alzheimer's and Parkinson's diseases, as well as non-neuropathic conditions such...
Should different countries participating in PISA interpret socioeconomic background in the same way? A measurement invariance approach
It has been claimed that there is a lack of theory-driven constructs and a lack of cross-country comparability in International Large-Scale Assessment (ILSA)’s socio-economic background scales. To address these issues, a new...
Restricted Proliferation During Neurogenesis Contributes to Regionalisation of the Amphioxus Nervous System.
The central nervous system of the cephalochordate amphioxus consists of a dorsal neural tube with an anterior brain. Two decades of gene expression analyses in developing amphioxus embryos have shown that, despite apparent...
Methods for generating year-round access to amphioxus in the laboratory.
Cephalochordates, commonly known as amphioxus, are key to understanding vertebrate origins. However, laboratory work suffers from limited access to adults and embryonic material. Here we report the design and experimental...
Sperm chemotaxis is driven by the slope of the chemoattractant concentration field.
Héctor Vicente Ramírez-Gómez, Vilma Jimenez Sabinina, Martín Velázquez Pérez, Carmen Beltran, Jorge Carneiro, Christopher D Wood, Idan Tuval, Alberto Darszon, Adán Guerrero
Mar 25, 2020
Spermatozoa of marine invertebrates are attracted to their conspecific female gamete by diffusive molecules, called chemoattractants, released from the egg investments in a process known as chemotaxis. The information from the...
On the nature and function of organizers.
Organizers, which comprise groups of cells with the ability to instruct adjacent cells into specific states, represent a key principle in developmental biology. The concept was first introduced by Spemann and Mangold, who showed...
Using self-adaptive optimisation methods to perform sequential optimisation for low-energy building design
The use of software tools to aid building design, or to show compliance, is now commonplace. This has motivated investigations into the potential of optimisation algorithms, used in such software, to automatically optimise...
Should different countries participating in PISA interpret socioeconomic background in the same way? A measurement invariance approach
It has been claimed that there is a lack of theory-driven constructs and a lack of cross-country comparability in International Large-Scale Assessment (ILSA)’s socio-economic background scales. To address these issues, a new...
Electronic Origin of α″ to β Phase Transformation in Ti-Nb-Based Thin Films upon Hf Microalloying.
José Julio Gutiérrez Moreno, Nikolaos T Panagiotopoulos, Georgios A Evangelakis, Christina E Lekka
Mar 15, 2020
We present results on thin Ti-Nb-based films containing Hf at various concentrations grown by magnetron sputtering. The films exhibit α" patterns at Hf concentrations up to 11 at.%, while at 16 at.% Hf, the β-phase emerges as a...
Multi-Class Cost-Constrained Random Coding for Correlated Sources over the Multiple-Access Channel.
This paper studies a generalized version of multi-class cost-constrained random-coding ensemble with multiple auxiliary costs for the transmission of N correlated sources over an N-user multiple-access channel. For...
Wnt/ß-catenin signalling and the dynamics of fate decisions in early mouse embryos and embryonic stem (ES) cells
tWnt/ß-catenin signalling is a widespread cell signalling pathway with multiple roles during vertebrate development. In mouse embryonic stem (mES) cells, there is a dual role for ß-catenin: it promotes differentiation when...
The structure of Wntch signalling and the resolution of transition states in development
During development, the emergence of different cell fates and their patterning into tissues and organs requires spatio-temporal coordination that controls the relative number of different cell types. Genetic analyses in...
The structure of Wntch signalling and the resolution of transition states in development
During development, the emergence of different cell fates and their patterning into tissues and organs requires spatio-temporal coordination that controls the relative number of different cell types. Genetic analyses in...
The reliability of inverse modelling for the wide scale characterization of the thermal properties of buildings
Alfonso P. Ramallo-González, Matthew Brown, Elizabeth Gabe-Thomas, Tom Lovett, David A. Coley
Jan 01, 0001
The reduction of energy use in buildings is a major component of greenhouse gas mitigation policy and requires knowledge of the fabric and the occupant behaviour. Hence there has been a longstanding desire to use automatic...
Energy efficiency inverse modelling lumped parameter model smart metre /dk/atira/pure/subjectarea/asjc/2200/2216 name=Architecture /dk/atira/pure/subjectarea/asjc/2200/2215 name=Building and Construction /dk/atira/pure/subjectarea/asjc/2600/2611 name=Modelling and Simulation /dk/atira/pure/subjectarea/asjc/1700/1706 name=Computer Science Applications /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy
Information-Theoretic Foundations of Mismatched Decoding
Shannon’s channel coding theorem characterizes the maximal rate of information that can be reliably transmitted over a communication channel when optimal encoding and decoding strategies are used. In many scenarios, however...
Multi-Class Cost-Constrained Random Coding for Correlated Sources over the Multiple-Access Channel
This paper studies a generalized version of multi-class cost-constrained random-coding ensemble with multiple auxiliary costs for the transmission of N correlated sources over an N-user multiple-access channel. For each user...
Wnt/ß-catenin signalling and the dynamics of fate decisions in early mouse embryos and embryonic stem (ES) cells
tWnt/ß-catenin signalling is a widespread cell signalling pathway with multiple roles during vertebrate development. In mouse embryonic stem (mES) cells, there is a dual role for ß-catenin: it promotes differentiation when...
Optical Fiber Sensors
Mohamed Elsherif, Ahmed E Salih, Monserrat Gutiérrez Muñoz, Fahad Alam, Bader AlQattan, Dennyson Savariraj Antonysamy, Mohamed Fawzi Zaki, Ali K Yetisen, Seongjun Park, Timothy D Wilkinson, Haider Butt
Jul 14, 2022
Fiber‐optic technology emerged originally for applications in data transmission and telecommunications. However, sensors based on fiber‐optics have been developed rapidly because of their excellent sensing performances and...
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