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Genomic analysis finds no evidence of canonical eukaryotic DNA processing complexes in a free-living protist.
Dayana E Salas-Leiva, Eelco C Tromer, Bruce A Curtis, Jon Jerlström-Hultqvist, Martin Kolisko, Zhenzhen Yi, Joan S Salas-Leiva, Lucie Gallot-Lavallée, Shelby K Williams, Geert JPL Kops, John M Archibald, Alastair GB Simpson, Andrew J Roger
Jan 05, 2022
Genomic analysis finds no evidence of canonical eukaryotic DNA processing complexes in a free-living protist
Membrane Interactions and Toxicity by Misfolded Protein Oligomers.
The conversion of otherwise soluble proteins into insoluble amyloid aggregates is associated with a range of neurodegenerative disorders, including Alzheimer's and Parkinson's diseases, as well as non-neuropathic conditions such...
Genomic analysis finds no evidence of canonical eukaryotic DNA processing complexes in a free-living protist.
Genomic analysis finds no evidence of canonical eukaryotic DNA processing complexes in a free-living protist.
Dayana E Salas-Leiva, Eelco C Tromer, Bruce A Curtis, Jon Jerlström-Hultqvist, Martin Kolisko, Zhenzhen Yi, Joan S Salas-Leiva, Lucie Gallot-Lavallée, Shelby K Williams, Geert JPL Kops, John M Archibald, Alastair GB Simpson, Andrew J Roger
Nov 22, 2021
Cells replicate and segregate their DNA with precision. Previous studies showed that these regulated cell-cycle processes were present in the last eukaryotic common ancestor and that their core molecular parts are conserved...
On the nature and function of organizers.
Organizers, which comprise groups of cells with the ability to instruct adjacent cells into specific states, represent a key principle in developmental biology. The concept was first introduced by Spemann and Mangold, who showed...
Using self-adaptive optimisation methods to perform sequential optimisation for low-energy building design
The use of software tools to aid building design, or to show compliance, is now commonplace. This has motivated investigations into the potential of optimisation algorithms, used in such software, to automatically optimise...
Multi-Class Cost-Constrained Random Coding for Correlated Sources over the Multiple-Access Channel.
This paper studies a generalized version of multi-class cost-constrained random-coding ensemble with multiple auxiliary costs for the transmission of N correlated sources over an N-user multiple-access channel. For...
Wnt/ß-catenin signalling and the dynamics of fate decisions in early mouse embryos and embryonic stem (ES) cells
tWnt/ß-catenin signalling is a widespread cell signalling pathway with multiple roles during vertebrate development. In mouse embryonic stem (mES) cells, there is a dual role for ß-catenin: it promotes differentiation when...
The structure of Wntch signalling and the resolution of transition states in development
During development, the emergence of different cell fates and their patterning into tissues and organs requires spatio-temporal coordination that controls the relative number of different cell types. Genetic analyses in...
The structure of Wntch signalling and the resolution of transition states in development
During development, the emergence of different cell fates and their patterning into tissues and organs requires spatio-temporal coordination that controls the relative number of different cell types. Genetic analyses in...
The reliability of inverse modelling for the wide scale characterization of the thermal properties of buildings
Alfonso P. Ramallo-González, Matthew Brown, Elizabeth Gabe-Thomas, Tom Lovett, David A. Coley
Jan 01, 0001
The reduction of energy use in buildings is a major component of greenhouse gas mitigation policy and requires knowledge of the fabric and the occupant behaviour. Hence there has been a longstanding desire to use automatic...
Energy efficiency inverse modelling lumped parameter model smart metre /dk/atira/pure/subjectarea/asjc/2200/2216 name=Architecture /dk/atira/pure/subjectarea/asjc/2200/2215 name=Building and Construction /dk/atira/pure/subjectarea/asjc/2600/2611 name=Modelling and Simulation /dk/atira/pure/subjectarea/asjc/1700/1706 name=Computer Science Applications /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy
Information-Theoretic Foundations of Mismatched Decoding
Shannon’s channel coding theorem characterizes the maximal rate of information that can be reliably transmitted over a communication channel when optimal encoding and decoding strategies are used. In many scenarios, however...
Multi-Class Cost-Constrained Random Coding for Correlated Sources over the Multiple-Access Channel
This paper studies a generalized version of multi-class cost-constrained random-coding ensemble with multiple auxiliary costs for the transmission of N correlated sources over an N-user multiple-access channel. For each user...
Wnt/ß-catenin signalling and the dynamics of fate decisions in early mouse embryos and embryonic stem (ES) cells
tWnt/ß-catenin signalling is a widespread cell signalling pathway with multiple roles during vertebrate development. In mouse embryonic stem (mES) cells, there is a dual role for ß-catenin: it promotes differentiation when...
New insights from GWAS on BMI-related growth traits in a longitudinal cohort of admixed children with Native American and European ancestry.
Lucas Vicuña, Esteban Barrientos, Tomás Norambuena, Danilo Alvares, Juan Cristobal Gana, Valeria Leiva-Yamaguchi, Cristian Meza, José L Santos, Veronica Mericq, Ana Pereira, Susana Eyheramendy
Mar 29, 2023
Body-mass index (BMI) is a hallmark of adiposity. In contrast with adulthood, the genetic architecture of BMI during childhood is poorly understood. The few genome-wide association studies (GWAS) on children have been performed...
Lumped parameter models for building thermal modelling
There are many sophisticated building simulators capable of accurately modelling the thermal performance of buildings. Lumped Parameter Models (LPMs) are an alternative which, due to their shorter computational time, can be used...
Neuro-mesodermal progenitors (NMPs)
The mammalian embryo's caudal lateral epiblast (CLE) harbours bipotent progenitors, called neural mesodermal progenitors (NMPs), that contribute to the spinal cord and the paraxial mesoderm throughout axial elongation. Here, we...
neuromesodermal progenitors Single cells Transcription Animals Body Patterning Cell Differentiation Cell Lineage Embryo Mammalian Embryonic Stem Cells Female Gene Expression Profiling Gene Expression Regulation Developmental Germ Layers Green Fluorescent Proteins In Vitro Techniques Male Mesoderm Mice Neural Stem Cells Pluripotent Stem Cells Spinal Cord Stem Cells Support Vector Machine Transcriptome
Using self-adaptive optimisation methods to perform sequential optimisation for low-energy building design
The use of software tools to aid building design, or to show compliance, is now commonplace. This has motivated investigations into the potential of optimisation algorithms, used in such software, to automatically optimise...
The structural and functional determinants of the Axin and Dishevelled DIX domains.
Adaptor Proteins Signal Transducing Amino Acid Sequence Animals Axin Protein Dimerization Dishevelled Proteins evolution Molecular Humans Molecular Sequence Data Mutation Phenotype Phosphoproteins Protein Interaction Domains and Motifs Protein Structure Tertiary Rats Repressor Proteins Sequence Alignment
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