Search
Results: 113
Synergistic Binding of bHLH Transcription Factors to the Promoter of the Maize NADP-ME Gene Used in C4 Photosynthesis Is Based on an Ancient Code Found in the Ancestral C3 State.
Ana Rita Borba, Tânia S Serra, Alicja Górska, Paulo Gouveia, André M Cordeiro, Ivan Reyna-Llorens, Jana Knerová, Pedro M Barros, Isabel A Abreu, Maria Margarida Oliveira, Julian M Hibberd, Nelson JM Saibo
Apr 30, 2018
C4 photosynthesis has evolved repeatedly from the ancestral C3 state to generate a carbon concentrating mechanism that increases photosynthetic efficiency. This specialized form of photosynthesis is particularly common in the...
TOPBP1 recruits TOP2A to ultra-fine anaphase bridges to aid in their resolution.
Ronan Broderick, Jadwiga Nieminuszczy, Andrew N Blackford, Alicja Winczura, Wojciech Niedzwiedz
May 22, 2015
Anaphase Antigens Neoplasm Carrier Proteins Cell Cycle Proteins Cell Line Tumor Centromere Chromatids Chromosomes DNA DNA Topoisomerases Type II DNA-Binding Proteins Gene Expression Regulation Gene Expression Regulation Neoplastic Green Fluorescent Proteins HEK293 Cells HeLa Cells Humans Microscopy Fluorescence Mitosis Mutation Nuclear Proteins Poly-ADP-Ribose Binding Proteins Protein Binding Protein Structure Tertiary
Inhibitors of immune checkpoints-PD-1, PD-L1, CTLA-4-new opportunities for cancer patients and a new challenge for internists and general practitioners.
Marek Z Wojtukiewicz, Magdalena M Rek, Kamil Karpowicz, Maria Górska, Barbara Polityńska, Anna M Wojtukiewicz, Marcin Moniuszko, Piotr Radziwon, Stephanie C Tucker, Kenneth V Honn
Oct 29, 2021
The treatment of cancer patients with immune checkpoint inhibitors (ICI) (anti-CTLA-4, anti-PD-1, anti-PD-L1, combined therapy anti-PD-1/PD-L1 with anti-CTLA-4) has without doubt been a significant breakthrough in the field of...
Digital Healthcare Innovations in the UK
The National Health Service (NHS) is one of the largest and best performinghealthcare systems in the world. It has provided universal coverage for 70 years, but today it is faced with the challenge of...
Mechanisms Underlying Disorders of Consciousness
Andrea I. Luppi, Joshua Cain, Lennart R. B. Spindler, Urszula J. Górska, Daniel Toker, Andrew E. Hudson, Emery N. Brown, Michael N. Diringer, Robert D. Stevens, Marcello Massimini, Martin M. Monti, Emmanuel A. Stamatakis, Melanie Boly
Jul 28, 2021
Fish consumption and frying of fish in relation to type 2 diabetes incidence
Alice Wallin, Daniela Di Giuseppe, Nicola Orsini, Agneta Åkesson, Nita G Forouhi, Alicja Wolk
Jan 13, 2016
cohort study fish Fried foods Methyl mercury Polychlorinated biphenyls Type 2 diabetes Aged Animals Cohort Studies Cooking Diabetes mellitus Type 2 Diet Healthy Diet High-Fat Fishes Follow-Up Studies Food Contamination Humans Incidence Male Methylmercury Compounds Middle Aged Patient Compliance Polychlorinated Biphenyls Proportional Hazards Models Prospective Studies Registries seafood Shellfish Sweden Water Pollutants
Mechanisms Underlying Disorders of Consciousness
Andrea I. Luppi, Joshua Cain, Lennart R. B. Spindler, Urszula J. Górska, Daniel Toker, Andrew E. Hudson, Emery N. Brown, Michael N. Diringer, Robert D. Stevens, Marcello Massimini, Martin M. Monti, Emmanuel A. Stamatakis, Melanie Boly
Oct 01, 2021
SARS-CoV-2 Papain-Like Protease Potential Inhibitors-In Silico Quantitative Assessment.
Adam Stasiulewicz, Alicja W Maksymiuk, Mai Lan Nguyen, Barbara Bełza, Joanna I Sulkowska
Apr 13, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) encodes the papain-like protease (PLpro). The protein not only plays an essential role in viral replication but also cleaves ubiquitin and ubiquitin-like...
covid-19 PLpro SARS-CoV-2 UCH-L1 coronavirus docking papain-like protease pharmacophore Virtual screening Animals Antiviral Agents Computer Simulation Coronavirus Papain-Like Proteases Crystallography X-Ray Databases Chemical Databases Protein Drug Evaluation Preclinical Humans Inhibitory Concentration 50 Lethal Dose 50 Ligands Mutagenicity Tests Protease Inhibitors Quantitative Structure-Activity Relationship Rats SARS-CoV-2 Ubiquitin Thiolesterase
Prevalence of overweight, obesity and thinness in 9-10 year old children in Mauritius.
Rishi Caleyachetty, Alicja R Rudnicka, Justin B Echouffo-Tcheugui, Karen R Siegel, Nigel Richards, Peter H Whincup
Oct 19, 2012
Mechanisms Underlying Disorders of Consciousness
Andrea I Luppi, Joshua Cain, Lennart RB Spindler, Urszula J Górska, Daniel Toker, Andrew E Hudson, Emery N Brown, Michael N Diringer, Robert D Stevens, Marcello Massimini, Martin M Monti, Emmanuel A Stamatakis, Melanie Boly, Curing Coma Campaign and Its Contributing Collaborators
Apr 01, 2022
Artificial intelligence-enabled retinal vasculometry for prediction of circulatory mortality, myocardial infarction and stroke.
Alicja Regina Rudnicka, Roshan Welikala, Sarah Barman, Paul J Foster, Robert Luben, Shabina Hayat, Kay-Tee Khaw, Peter Whincup, David Strachan, Christopher G Owen
Sep 30, 2022
Amino acid variants of SARS-CoV-2 papain-like protease have impact on drug binding.
Agata P Perlinska, Adam Stasiulewicz, Mai Lan Nguyen, Karolina Swiderska, Mikolaj Zmudzinski, Alicja W Maksymiuk, Marcin Drag, Joanna I Sulkowska
Dec 08, 2022
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused both a health and economic crisis around the world. Its papain-like protease (PLpro) is one of the protein targets utilized in designing new drugs...
The contribution of physical fitness to individual and ethnic differences in risk markers for type 2 diabetes in children
Claire M Nightingale, Alicja R Rudnicka, Sarah R Kerry-Barnard, Angela S Donin, Soren Brage, Kate L Westgate, Ulf Ekelund, Derek G Cook, Christopher G Owen, Peter H Whincup
Mar 02, 2018
BACKGROUND: The relationship between physical fitness and risk markers for type 2 diabetes (T2D) in children and the contribution to ethnic differences in these risk markers have been little studied. We examined associations...
Relationships among streptococci from the mitis group, misidentified as Streptococcus pneumoniae
Ewa Sadowy, Agnieszka Bojarska, Alicja Kuch, Anna Skoczyńska, Keith A. Jolley, Martin C. J. Maiden, Andries J. van Tonder, Sven Hammerschmidt, Waleria Hryniewicz
Sep 12, 2020
Abstract: The aim of our study was to investigate phenotypic and genotypic features of streptococci misidentified (misID) as Streptococcus pneumoniae, obtained over 20 years from hospital patients in Poland. Sixty-three isolates...
Loss of inhibition in sensorimotor networks in focal hand dystonia.
Cecile Gallea, Priyantha Herath, Valerie Voon, Alicja Lerner, John Ostuni, Ziad Saad, Shantalaxmi Thada, Jeffrey Solomon, Silvina G Horovitz, Mark Hallett
Jun 04, 2018
OBJECTIVE: To investigate GABA-ergic receptor density and associated brain functional and grey matter changes in focal hand dystonia (FHD). METHODS: 18 patients with FHD of the right hand and 18 age and gender matched healthy...
cerebellum Focal dystonia INHIBITION Motor Cortex Movement disorder Adult Aged Brain Mapping Carbon Radioisotopes Case-Control Studies cerebellum Cerebrovascular Circulation Dystonic Disorders Female Flumazenil GABA Modulators Humans Magnetic Resonance Imaging Male Middle Aged Neural Pathways oxygen isotopes Oxygen Radioisotopes Positron-Emission Tomography Prefrontal Cortex Young Adult
Immune cells lacking Y chromosome show dysregulation of autosomal gene expression.
Jan P Dumanski, Jonatan Halvardson, Hanna Davies, Edyta Rychlicka-Buniowska, Jonas Mattisson, Behrooz Torabi Moghadam, Noemi Nagy, Kazimierz Węglarczyk, Karolina Bukowska-Strakova, Marcus Danielsson, Paweł Olszewski, Arkadiusz Piotrowski, Erin Oerton, Aleksandra Ambicka, Marcin Przewoźnik, Łukasz Bełch, Tomasz Grodzicki, Piotr L Chłosta, Stefan Imreh, Vilmantas Giedraitis, Lena Kilander, Jessica Nordlund, Adam Ameur, Ulf Gyllensten, Åsa Johansson, Alicja Józkowicz, Maciej Siedlar, Alicja Klich-Rączka, Janusz Jaszczyński, Stefan Enroth, Jarosław Baran, Martin Ingelsson, John RB Perry, Janusz Ryś, Lars A Forsberg
Apr 26, 2021
Epidemiological investigations show that mosaic loss of chromosome Y (LOY) in leukocytes is associated with earlier mortality and morbidity from many diseases in men. LOY is the most common acquired mutation and is associated...
Mechanisms Underlying Disorders of Consciousness
Andrea Luppi, Joshua Cain, Lennart Spindler, Urszula J Górska, Daniel Toker, Andrew E Hudson, Emery N Brown, Michael N Diringer, Robert D Stevens, Marcello Massimini, Martin M Monti, Emmanuel Stamatakis, Melanie Boly, Curing Coma Campaign and Its Contributing Collaborators
Jan 28, 2022
Relationships among streptococci from the mitis group, misidentified as Streptococcus pneumoniae.
Ewa Sadowy, Agnieszka Bojarska, Alicja Kuch, Anna Skoczyńska, Keith A Jolley, Martin CJ Maiden, Andries J van Tonder, Sven Hammerschmidt, Waleria Hryniewicz
May 20, 2021
The aim of our study was to investigate phenotypic and genotypic features of streptococci misidentified (misID) as Streptococcus pneumoniae, obtained over 20 years from hospital patients in Poland. Sixty-three isolates...
Mechanisms Underlying Disorders of Consciousness
Andrea I. Luppi, Joshua Cain, Lennart R. B. Spindler, Urszula J. Górska, Daniel Toker, Andrew E. Hudson, Emery N. Brown, Michael N. Diringer, Robert D. Stevens, Marcello Massimini, Martin M. Monti, Emmanuel A. Stamatakis, Melanie Boly
Sep 15, 2021
Mechanisms Underlying Disorders of Consciousness
Andrea I Luppi, Joshua Cain, Lennart R B Spindler, Urszula J Górska, Daniel Toker, Andrew E Hudson, Emery N Brown, Michael N Diringer, Robert D Stevens, Marcello Massimini, Martin M Monti, Emmanuel A Stamatakis, Melanie Boly
Aug 11, 2021
Aim
In order to successfully detect, classify, prognosticate, and develop targeted therapies for patients with disorders of consciousness (DOC), it is crucial to improve our mechanistic understanding of how severe brain...
Electroencephalography MECHANISM Brain injury Consciousness Magnetic Resonance Imaging Coma Neuroimaging
Published by: Neurocritical care
Family and home correlates of children's physical activity in a multi-ethnic population
Alison M McMinn, Esther Mf van Sluijs, Claire M Nightingale, Simon J Griffin, Derek G Cook, Chris G Owen, Alicja R Rudnicka, Peter H Whincup
Jun 16, 2011
Aspen Tension Wood Fibers Contain β-(1---> 4)-Galactans and Acidic Arabinogalactans Retained by Cellulose Microfibrils in Gelatinous Walls.
Tatyana Gorshkova, Natalia Mokshina, Tatyana Chernova, Nadezhda Ibragimova, Vadim Salnikov, Polina Mikshina, Theodora Tryfona, Alicja Banasiak, Peter Immerzeel, Paul Dupree, Ewa J Mellerowicz
Dec 15, 2015
Amino acid variants of SARS-CoV-2 papain-like protease have impact on drug binding.
Agata P Perlinska, Adam Stasiulewicz, Mai Lan Nguyen, Karolina Swiderska, Mikolaj Zmudzinski, Alicja W Maksymiuk, Marcin Drag, Joanna I Sulkowska
Dec 22, 2022
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused both a health and economic crisis around the world. Its papain-like protease (PLpro) is one of the protein targets utilized in designing new drugs...
Mechanisms Underlying Disorders of Consciousness
Andrea Luppi, Joshua Cain, Lennart Spindler, Urszula J Górska, Daniel Toker, Andrew E Hudson, Emery N Brown, Michael N Diringer, Robert D Stevens, Marcello Massimini, Martin M Monti, Emmanuel Stamatakis, Melanie Boly, Curing Coma Campaign and Its Contributing Collaborators
Jul 05, 2021
|
|< |
< |
1 |