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Results: 225
TOPBP1 recruits TOP2A to ultra-fine anaphase bridges to aid in their resolution.
Ronan Broderick, Jadwiga Nieminuszczy, Andrew N Blackford, Alicja Winczura, Wojciech Niedzwiedz
May 22, 2015
Anaphase Antigens Neoplasm Carrier Proteins Cell Cycle Proteins Cell Line Tumor Centromere Chromatids Chromosomes DNA DNA Topoisomerases Type II DNA-Binding Proteins Gene Expression Regulation Gene Expression Regulation Neoplastic Green Fluorescent Proteins HEK293 Cells HeLa Cells Humans Microscopy Fluorescence Mitosis Mutation Nuclear Proteins Poly-ADP-Ribose Binding Proteins Protein Binding Protein Structure Tertiary
The Grizzly, November 13, 1990
Krishni Patrick, Sara Jacobson, Kristin White, Adria Harris, Erika Compton, Nancy Imes, Kathleen Bowers, Cassandra Yutzy, Satsuki Scoville, Terri Johnson, Judd Woytek, Matt Becker, Ellen Shatz, Dawn Delaney, Chris Heinzinger, Dennis Moir, Trey Gelston, Neil Schafer, Todd Koser, Eric Bleickardt, Brian Toleno, Joe Mulholland, Chris Foust, Katherine Grim, Jon Volkmer
Jan 01, 0001
Clergy Assembly Meets Ninth Consecutive Year Career Day: An Information Session for Students U.S. Energy Policy Anti-American? The Ursinus Tutoring Program Being British Without Being English Election Results Students...
Ursinus College Collegeville Pennsylvania newspaper pre-medical students John Kelly Rick Bott Zeta Chi Basketball Football Joe Kershner Senta Bamberger cross-country Swimming Barbara Hutchison Michael Winship ProTheatre sororities Franklin W. Olin campus security Gary Hodgson Wilkinson Hall recycling Reimert Hall tutoring Llewylyn Morgan James A. Forbes career networking cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Digital Healthcare Innovations in the UK
The National Health Service (NHS) is one of the largest and best performinghealthcare systems in the world. It has provided universal coverage for 70 years, but today it is faced with the challenge of...
Fish consumption and frying of fish in relation to type 2 diabetes incidence
Alice Wallin, Daniela Di Giuseppe, Nicola Orsini, Agneta Åkesson, Nita G Forouhi, Alicja Wolk
Jan 13, 2016
cohort study fish Fried foods Methyl mercury Polychlorinated biphenyls Type 2 diabetes Aged Animals Cohort Studies Cooking Diabetes mellitus Type 2 Diet Healthy Diet High-Fat Fishes Follow-Up Studies Food Contamination Humans Incidence Male Methylmercury Compounds Middle Aged Patient Compliance Polychlorinated Biphenyls Proportional Hazards Models Prospective Studies Registries seafood Shellfish Sweden Water Pollutants
SARS-CoV-2 Papain-Like Protease Potential Inhibitors-In Silico Quantitative Assessment.
Adam Stasiulewicz, Alicja W Maksymiuk, Mai Lan Nguyen, Barbara Bełza, Joanna I Sulkowska
Apr 13, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) encodes the papain-like protease (PLpro). The protein not only plays an essential role in viral replication but also cleaves ubiquitin and ubiquitin-like...
covid-19 PLpro SARS-CoV-2 UCH-L1 coronavirus docking papain-like protease pharmacophore Virtual screening Animals Antiviral Agents Computer Simulation Coronavirus Papain-Like Proteases Crystallography X-Ray Databases Chemical Databases Protein Drug Evaluation Preclinical Humans Inhibitory Concentration 50 Lethal Dose 50 Ligands Mutagenicity Tests Protease Inhibitors Quantitative Structure-Activity Relationship Rats SARS-CoV-2 Ubiquitin Thiolesterase
Prevalence of overweight, obesity and thinness in 9-10 year old children in Mauritius.
Rishi Caleyachetty, Alicja R Rudnicka, Justin B Echouffo-Tcheugui, Karen R Siegel, Nigel Richards, Peter H Whincup
Oct 19, 2012
Disease-specific variant pathogenicity prediction significantly improves variant interpretation in inherited cardiac conditions
Xiaolei Zhang, Roddy Walsh, Nicola Whiffin, Rachel Buchan, William Midwinter, Alicja Wilk, Risha Govind, Nicholas Li, Mian Ahmad, Francesco Mazzarotto, Angharad Roberts, Pantazis I. Theotokis, Erica Mazaika, Mona Allouba, Antonio de Marvao, Chee Jian Pua, Sharlene M. Day, Euan Ashley, Steven D. Colan, Michelle Michels, Alexandre C. Pereira, Daniel Jacoby, Carolyn Y. Ho, Iacopo Olivotto, Gunnar T. Gunnarsson, John L. Jefferies, Chris Semsarian, Jodie Ingles, Declan P. O’Regan, Yasmine Aguib, Magdi H. Yacoub, Stuart A. Cook, Paul J. R. Barton, Leonardo Bottolo, James S. Ware
Oct 13, 2021
Disease-specific variant pathogenicity prediction significantly improves variant interpretation in inherited cardiac conditions
Xiaolei Zhang, Roddy Walsh, Nicola Whiffin, Rachel Buchan, William Midwinter, Alicja Wilk, Risha Govind, Nicholas Li, Mian Ahmad, Francesco Mazzarotto, Angharad Roberts, Pantazis I. Theotokis, Erica Mazaika, Mona Allouba, Antonio de Marvao, Chee Jian Pua, Sharlene M. Day, Euan Ashley, Steven D. Colan, Michelle Michels, Alexandre C. Pereira, Daniel Jacoby, Carolyn Y. Ho, Iacopo Olivotto, Gunnar T. Gunnarsson, John L. Jefferies, Chris Semsarian, Jodie Ingles, Declan P. O’Regan, Yasmine Aguib, Magdi H. Yacoub, Stuart A. Cook, Paul J. R. Barton, Leonardo Bottolo, James S. Ware
Jan 07, 2021
Artificial intelligence-enabled retinal vasculometry for prediction of circulatory mortality, myocardial infarction and stroke.
Alicja Regina Rudnicka, Roshan Welikala, Sarah Barman, Paul J Foster, Robert Luben, Shabina Hayat, Kay-Tee Khaw, Peter Whincup, David Strachan, Christopher G Owen
Sep 30, 2022
Amino acid variants of SARS-CoV-2 papain-like protease have impact on drug binding.
Agata P Perlinska, Adam Stasiulewicz, Mai Lan Nguyen, Karolina Swiderska, Mikolaj Zmudzinski, Alicja W Maksymiuk, Marcin Drag, Joanna I Sulkowska
Dec 08, 2022
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused both a health and economic crisis around the world. Its papain-like protease (PLpro) is one of the protein targets utilized in designing new drugs...
The contribution of physical fitness to individual and ethnic differences in risk markers for type 2 diabetes in children
Claire M Nightingale, Alicja R Rudnicka, Sarah R Kerry-Barnard, Angela S Donin, Soren Brage, Kate L Westgate, Ulf Ekelund, Derek G Cook, Christopher G Owen, Peter H Whincup
Mar 02, 2018
BACKGROUND: The relationship between physical fitness and risk markers for type 2 diabetes (T2D) in children and the contribution to ethnic differences in these risk markers have been little studied. We examined associations...
Relationships among streptococci from the mitis group, misidentified as Streptococcus pneumoniae
Ewa Sadowy, Agnieszka Bojarska, Alicja Kuch, Anna Skoczyńska, Keith A. Jolley, Martin C. J. Maiden, Andries J. van Tonder, Sven Hammerschmidt, Waleria Hryniewicz
Sep 12, 2020
Abstract: The aim of our study was to investigate phenotypic and genotypic features of streptococci misidentified (misID) as Streptococcus pneumoniae, obtained over 20 years from hospital patients in Poland. Sixty-three isolates...
Loss of inhibition in sensorimotor networks in focal hand dystonia.
Cecile Gallea, Priyantha Herath, Valerie Voon, Alicja Lerner, John Ostuni, Ziad Saad, Shantalaxmi Thada, Jeffrey Solomon, Silvina G Horovitz, Mark Hallett
Jun 04, 2018
OBJECTIVE: To investigate GABA-ergic receptor density and associated brain functional and grey matter changes in focal hand dystonia (FHD). METHODS: 18 patients with FHD of the right hand and 18 age and gender matched healthy...
cerebellum Focal dystonia INHIBITION Motor Cortex Movement disorder Adult Aged Brain Mapping Carbon Radioisotopes Case-Control Studies cerebellum Cerebrovascular Circulation Dystonic Disorders Female Flumazenil GABA Modulators Humans Magnetic Resonance Imaging Male Middle Aged Neural Pathways oxygen isotopes Oxygen Radioisotopes Positron-Emission Tomography Prefrontal Cortex Young Adult
Immune cells lacking Y chromosome show dysregulation of autosomal gene expression.
Jan P Dumanski, Jonatan Halvardson, Hanna Davies, Edyta Rychlicka-Buniowska, Jonas Mattisson, Behrooz Torabi Moghadam, Noemi Nagy, Kazimierz Węglarczyk, Karolina Bukowska-Strakova, Marcus Danielsson, Paweł Olszewski, Arkadiusz Piotrowski, Erin Oerton, Aleksandra Ambicka, Marcin Przewoźnik, Łukasz Bełch, Tomasz Grodzicki, Piotr L Chłosta, Stefan Imreh, Vilmantas Giedraitis, Lena Kilander, Jessica Nordlund, Adam Ameur, Ulf Gyllensten, Åsa Johansson, Alicja Józkowicz, Maciej Siedlar, Alicja Klich-Rączka, Janusz Jaszczyński, Stefan Enroth, Jarosław Baran, Martin Ingelsson, John RB Perry, Janusz Ryś, Lars A Forsberg
Apr 26, 2021
Epidemiological investigations show that mosaic loss of chromosome Y (LOY) in leukocytes is associated with earlier mortality and morbidity from many diseases in men. LOY is the most common acquired mutation and is associated...
Disease-specific variant pathogenicity prediction significantly improves variant interpretation in inherited cardiac conditions
Xiaolei Zhang, Roddy Walsh, Nicola Whiffin, Rachel Buchan, William Midwinter, Alicja Wilk, Risha Govind, Nicholas Li, Mian Ahmad, Francesco Mazzarotto, Angharad Roberts, Pantazis I. Theotokis, Erica Mazaika, Mona Allouba, Antonio de Marvao, Chee Jian Pua, Sharlene M. Day, Euan Ashley, Steven D. Colan, Michelle Michels, Alexandre C. Pereira, Daniel Jacoby, Carolyn Y. Ho, Iacopo Olivotto, Gunnar T. Gunnarsson, John L. Jefferies, Chris Semsarian, Jodie Ingles, Declan P. O’Regan, Yasmine Aguib, Magdi H. Yacoub, Stuart A. Cook, Paul J. R. Barton, Leonardo Bottolo, James S. Ware
Jan 16, 2021
Relationships among streptococci from the mitis group, misidentified as Streptococcus pneumoniae.
Ewa Sadowy, Agnieszka Bojarska, Alicja Kuch, Anna Skoczyńska, Keith A Jolley, Martin CJ Maiden, Andries J van Tonder, Sven Hammerschmidt, Waleria Hryniewicz
May 20, 2021
The aim of our study was to investigate phenotypic and genotypic features of streptococci misidentified (misID) as Streptococcus pneumoniae, obtained over 20 years from hospital patients in Poland. Sixty-three isolates...
Disease-specific variant pathogenicity prediction significantly improves variant interpretation in inherited cardiac conditions.
Xiaolei Zhang, Roddy Walsh, Nicola Whiffin, Rachel Buchan, William Midwinter, Alicja Wilk, Risha Govind, Nicholas Li, Mian Ahmad, Francesco Mazzarotto, Angharad Roberts, Pantazis I Theotokis, Erica Mazaika, Mona Allouba, Antonio de Marvao, Chee Jian Pua, Sharlene M Day, Euan Ashley, Steven D Colan, Michelle Michels, Alexandre C Pereira, Daniel Jacoby, Carolyn Y Ho, Iacopo Olivotto, Gunnar T Gunnarsson, John L Jefferies, Chris Semsarian, Jodie Ingles, Declan P O'Regan, Yasmine Aguib, Magdi H Yacoub, Stuart A Cook, Paul JR Barton, Leonardo Bottolo, James S Ware
Oct 20, 2020
PURPOSE: Accurate discrimination of benign and pathogenic rare variation remains a priority for clinical genome interpretation. State-of-the-art machine learning variant prioritization tools are imprecise and ignore important...
Magnetization transfer imaging of ovarian cancer
Surrin S Deen, Mary A McLean, Andrew B Gill, Robin AF Crawford, John Latimer, Peter Baldwin, Helena M Earl, Christine A Parkinson, Sarah Smith, Charlotte Hodgkin, Mercedes Jimenez-Linan, Cara R Brodie, Ilse Patterson, Helen C Addley, Susan J Freeman, Penelope M Moyle, Martin J Graves, Evis Sala, James D Brenton, Ferdia A Gallagher
Oct 15, 2022
OBJECTIVES: To investigate the relationship between magnetization transfer (MT) imaging and tissue macromolecules in high-grade serous ovarian cancer (HGSOC) and whether MT ratio (MTR) changes following neoadjuvant chemotherapy...
Aspen Tension Wood Fibers Contain β-(1---> 4)-Galactans and Acidic Arabinogalactans Retained by Cellulose Microfibrils in Gelatinous Walls.
Tatyana Gorshkova, Natalia Mokshina, Tatyana Chernova, Nadezhda Ibragimova, Vadim Salnikov, Polina Mikshina, Theodora Tryfona, Alicja Banasiak, Peter Immerzeel, Paul Dupree, Ewa J Mellerowicz
Dec 15, 2015
Family and home correlates of children's physical activity in a multi-ethnic population
Alison M McMinn, Esther Mf van Sluijs, Claire M Nightingale, Simon J Griffin, Derek G Cook, Chris G Owen, Alicja R Rudnicka, Peter H Whincup
Jun 16, 2011
Manipulation of autophagy in phagocytes facilitates <i>Staphylococcus aureus</i> bloodstream infection
Kate M. O'Keefe, Miesko M. Wilk, John M. Leech, Alison G. Murphy, Maisem Laabei, Ian R. Monk, Ruth C. Massey, Jodi A. Lindsay, Timothy J. Foster, Joan A. Geoghegan, Rachel M. McLoughlin
Sep 01, 2015
The capacity for intracellular survival within phagocytes is likely a critical factor facilitating S. aureus dissemination in the host. To date, the majority of work on S. aureus-phagocyte interactions has focused on neutrophils...
Manipulation of autophagy in phagocytes facilitates <i>Staphylococcus aureus</i> bloodstream infection
Kate M. O'Keefe, Miesko M. Wilk, John M. Leech, Alison G. Murphy, Maisem Laabei, Ian R. Monk, Ruth C. Massey, Jodi A. Lindsay, Timothy J. Foster, Joan A. Geoghegan, Rachel M. McLoughlin
Sep 01, 2015
The capacity for intracellular survival within phagocytes is likely a critical factor facilitating S. aureus dissemination in the host. To date, the majority of work on S. aureus-phagocyte interactions has focused on neutrophils...
Amino acid variants of SARS-CoV-2 papain-like protease have impact on drug binding.
Agata P Perlinska, Adam Stasiulewicz, Mai Lan Nguyen, Karolina Swiderska, Mikolaj Zmudzinski, Alicja W Maksymiuk, Marcin Drag, Joanna I Sulkowska
Dec 22, 2022
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused both a health and economic crisis around the world. Its papain-like protease (PLpro) is one of the protein targets utilized in designing new drugs...
Stochastic combinations of actin regulatory proteins are sufficient to drive filopodia formation.
Ulrich Dobramysl, Iris Katharina Jarsch, Yoshiko Inoue, Hanae Shimo, Benjamin Richier, Jonathan R Gadsby, Julia Mason, Alicja Szałapak, Pantelis Savvas Ioannou, Guilherme Pereira Correia, Astrid Walrant, Richard Butler, Edouard Hannezo, Benjamin D Simons, Jennifer L Gallop
Mar 19, 2021
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