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Random lattice triangulations
The paper concerns lattice triangulations, that is, triangulations of the integer points in a polygon in R 2 whose vertices are also integer points. Lattice triangulations have been studied extensively both as geometric objects...
Mobile geometric graphs
We consider the following dynamic Boolean model introduced by van den Berg et al. (Stoch. Process. Appl. 69:247–257, 1997). At time 0, let the nodes of the graph be a Poisson point process in Rd with constant intensity and let...
Mobile geometric graphs
We consider the following dynamic Boolean model introduced by van den Berg et al. (Stoch. Process. Appl. 69:247–257, 1997). At time 0, let the nodes of the graph be a Poisson point process in Rd with constant intensity and let...
Dynamics of lattice triangulations on thin rectangles
We consider random lattice triangulations of $n\times k$ rectangular regions with weight $\lambda^{|\sigma|}$ where $\lambda>0$ is a parameter and $|\sigma|$ denotes the total edge length of the triangulation. When...
Dynamics of lattice triangulations on thin rectangles
We consider random lattice triangulations of $n\times k$ rectangular regions with weight $\lambda^{|\sigma|}$ where $\lambda>0$ is a parameter and $|\sigma|$ denotes the total edge length of the triangulation. When...
Random lattice triangulations
The paper concerns lattice triangulations, that is, triangulations of the integer points in a polygon in R 2 whose vertices are also integer points. Lattice triangulations have been studied extensively both as geometric objects...
UK Third Sector grant making
Grant-making in the UK is a big industry, worth between £3 and £4bn per annum , consisting of grant-makers who wish to fund worthy causes aligned to their funding objectives, and charities and community groups who depend on...
UK Third Sector grant making
Grant-making in the UK is a big industry, worth between £3 and £4bn per annum , consisting of grant-makers who wish to fund worthy causes aligned to their funding objectives, and charities and community groups who depend on...
Regulation of human cytomegalovirus transcription in latency
Lytic infection of differentiated cell types with human cytomegalovirus (HCMV) results in the temporal expression of between 170-200 open reading frames (ORFs). A number of studies have demonstrated the temporal regulation of...
Understanding HCMV Latency Using Unbiased Proteomic Analyses
Human cytomegalovirus (HCMV) establishes either a latent (non-productive) or lytic (productive) infection depending upon cell type, cytokine milieu and the differentiation status of the infected cell. Undifferentiated cells...
The Human Cytomegalovirus β2.7 Long Non-Coding RNA Prevents Induction of Reactive Oxygen Species to Maintain Viral Gene Silencing during Latency
Human cytomegalovirus (HCMV) is a significant source of disease for the immunosuppressed and immunonaive. The treatment of HCMV is made more problematic by viral latency, a lifecycle stage in which the virus reduces its...
E-procurement quality from an internal customer perspective
Alistair Brandon-Jones
Jan 01, 0001
Purpose: Despite significant investment in e-procurement by many organisations, perceived failings in the quality of such technologies and of the support provided to use them – termed here e-procurement quality – continue to...
The intimate relationship between human cytomegalovirus and the dendritic cell lineage.
Primary infection of healthy individuals with human cytomegalovirus (HCMV) is normally asymptomatic but results in the establishment of a lifelong infection of the host. One important cellular reservoir of HCMV latency is the...
Human cytomegalovirus gene UL76 induces IL-8 expression through activation of the DNA damage response.
Human cytomegalovirus (HCMV), a β-herpesvirus, has evolved many strategies to subvert both innate and adaptive host immunity in order to ensure its survival and propagation within the host. Induction of IL-8 is particularly...
Ataxia Telangiectasia Mutated Proteins Cell Line Cell Nucleus Cytomegalovirus Cytomegalovirus Infections DNA Damage Genes Reporter Host-Pathogen Interactions Humans I-kappa B Kinase Interleukin-8 Mutation Protein Transport Proteolysis RNA Interference Recombinant Proteins Signal Transduction Trans-Activators Transcription Factor RelA Up-Regulation Virus Replication
HCMV Antivirals and Strategies to Target the Latent Reservoir.
Human cytomegalovirus (HCMV) is a ubiquitous human herpesvirus. In healthy people, primary infection is generally asymptomatic, and the virus can go on to establish lifelong latency in cells of the myeloid lineage. However, HCMV...
Published by: Viruses
A Viral Long Non-Coding RNA Protects against Cell Death during Human Cytomegalovirus Infection of CD14+ Monocytes.
Apoptosis human cytomegalovirus latency long non-coding RNA Oxidative Stress Reactive Oxygen Species antioxidants Apoptosis Cells Cultured Cytomegalovirus Humans Lipopolysaccharide Receptors Mitochondria Monocytes Mutation Oxidative Stress RNA Long Noncoding RNA Viral Reactive Oxygen Species Virus Latency
A Viral Long Non-Coding RNA Protects against Cell Death during Human Cytomegalovirus Infection of CD14+ Monocytes
Long non-coding RNA β2.7 is the most highly transcribed viral gene during latent human cytomegalovirus (HCMV) infection. However, as yet, no function has ever been ascribed to β2.7 during HCMV latency. Here we show that...
Advances in the treatment of cytomegalovirus.
antivirals human cytomegalovirus Infection latency vaccines Antiviral Agents Cytomegalovirus Cytomegalovirus Infections Cytomegalovirus Vaccines Drug development Early Diagnosis Hematopoietic Stem Cell Transplantation Humans Immunity Cellular Immunoglobulins Immunosuppression Therapy Infant Newborn Organ Transplantation Perinatal Care Virus Latency
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