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Results: 52
The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage.
Julianne Kitevski-LeBlanc, Amélie Fradet-Turcotte, Predrag Kukic, Marcus D Wilson, Guillem Portella, Tairan Yuwen, Stephanie Panier, Shili Duan, Marella D Canny, Hugo van Ingen, Cheryl H Arrowsmith, John L Rubinstein, Michele Vendruscolo, Daniel Durocher, Lewis E Kay
Nov 15, 2017
Site-specific histone ubiquitylation plays a central role in orchestrating the response to DNA double-strand breaks (DSBs). DSBs elicit a cascade of events controlled by the ubiquitin ligase RNF168, which promotes the...
The enigmatic origins of the human brain.
Evolutionary history of the human brain appears more complex than thought
Amélie Beaudet
Apr 21, 2021
Immature acute leukaemias
Thomas Lefeivre, Luke Jones, Amélie Trinquand, Antoine Pinton, Elizabeth Macintyre, Elisa Laurenti, Jonathan Bond
May 26, 2021
It is essential to relate the biology of acute leukaemia to normal blood cell development. In this review, we discuss how modern models of haematopoiesis might inform approaches to diagnosis and management of immature...
Immature acute leukaemias
Thomas Lefeivre, Luke Jones, Amélie Trinquand, Antoine Pinton, Elizabeth Macintyre, Elisa Laurenti, Jonathan Bond
Jun 10, 2021
State‐of‐the‐Art Review State‐of‐the‐Art Reviews acute leukaemia acute myeloid leukaemia early thymic precursor‐ALL Haematopoiesis ICGS mixed‐phenotype acute leukaemia
Published by: The FEBS Journal
A comparative study of the endocasts of OH 5 and SK 1585
The taxonomy, phylogeny, and biology of theParanthropusspecies have been the center of debates since the earliest discoveryof the TM 1517 cranium (now attributed toParanthropus robustus)from the Plio-Pleistocene site of...
Preliminary paleohistological observations of the StW 573 ('Little Foot') skull.
Amélie Beaudet, Robert C Atwood, Winfried Kockelmann, Vincent Fernandez, Thomas Connolley, Nghia Trong Vo, Ronald Clarke, Dominic Stratford
Apr 19, 2021
Numerous aspects of early hominin biology remain debated or simply unknown. However, recent developments in high-resolution imaging techniques have opened new avenues in the field of paleoanthropology. More specifically, X-ray...
Comparative anatomy of the carotid canal in the Miocene small-bodied catarrhine Pliobates cataloniae.
Florian Bouchet, Alessandro Urciuoli, Amélie Beaudet, Marta Pina, Salvador Moyà-Solà, David M Alba
Nov 16, 2021
The small-bodied Miocene catarrhine Pliobates cataloniae (11.6 Ma, Spain) displays a mosaic of catarrhine symplesiomorphies and hominoid synapomorphies that hinders deciphering its phylogenetic relationships. Based on cladistic...
Autophagy plays an important role in protecting Pacific oysters from OsHV-1 and Vibrio aestuarianus infections.
Pierrick Moreau, Kevin Moreau, Amélie Segarra, Delphine Tourbiez, Marie-Agnès Travers, David C Rubinsztein, Tristan Renault
May 15, 2015
Autophagy Crassostrea gigas OsHV-1 Pacific oyster Vibrio aestuarianus ATG autophagy-related Atg8–PE Atg8–phosphatidylethenolamine DNA deoxyribonucleic acid hpi hours postinfection LC3-II cleaved lipidated and autophagosome-associated form of LC3 MAP1LC3A/B (LC3A/B) microtubule-associated proteins 1 light chain 3 alpha/beta (mammalian orthologs of the predicted Crassostrea gigas LC3 and yeast Atg8) NH4Cl ammonium chloride OsHV-1 Ostreid herpesvirus 1 pcr polymerase chain reaction
A comparative analysis of the vestibular apparatus in Epipliopithecus vindobonensis
Alessandro Urciuoli, Clément Zanolli, Amélie Beaudet, Marta Pina, Sergio Almécija, Salvador Moyà-Solà, David M Alba
May 24, 2021
Pliopithecoids are an extinct group of catarrhine primates from the Miocene of Eurasia. More than 50 years ago, they were linked to hylobatids due to some morphological similarities, but most subsequent studies have supported a...
ERα-36 regulates progesterone receptor activity in breast cancer.
Henri-Philippe Konan, Loay Kassem, Soleilmane Omarjee, Ausra Surmieliova-Garnès, Julien Jacquemetton, Elodie Cascales, Amélie Rezza, Olivier Trédan, Isabelle Treilleux, Coralie Poulard, Muriel Le Romancer
May 20, 2021
BACKGROUND: Alterations in estrogen and progesterone signaling, via their respective receptors, estrogen receptor alpha (ERα) and progesterone receptor (PR), respectively, are largely involved in the development of breast cancer...
Preliminary paleohistological observations of the StW 573 (‘Little Foot’) skull
Amélie Beaudet, Robert C Atwood, Winfried Kockelmann, Vincent Fernandez, Thomas Connolley, Nghia Trong Vo, Ronald Clarke, Dominic Stratford
Mar 03, 2021
Leupaxin Expression Is Dispensable for B Cell Immune Responses.
Amélie Bonaud, Simon Clare, Valeria Bisio, John M Sowerby, Shugang Yao, Hanne Ostergaard, Karl Balabanian, Kenneth GC Smith, Marion Espéli
Mar 03, 2020
B cells cell activation humoral immune response leupaxin Plasma Cells Animals Antibody Formation B-Lymphocytes Cell Adhesion Molecules Cell Differentiation Cells Cultured Germinal Center Immunity Humoral Lymphocyte Activation Mice Mice Knockout Plasma Cells Receptors Antigen B-Cell Signal Transduction Transcription Factors
Fcα Receptor-1-Activated Monocytes Promote B Lymphocyte Migration and IgA Isotype Switching.
Amélie V Bos, Melissa MJ van Gool, Annelot C Breedveld, Richard van der Mast, Casper Marsman, Gerd Bouma, Mark A van de Wiel, S Marieke van Ham, Reina E Mebius, Marjolein van Egmond
Nov 16, 2022
Patients with inflammatory bowel disease (IBD) produce enhanced immunoglobulin A (IgA) against the microbiota compared to healthy individuals, which has been correlated with disease severity. Since IgA complexes can potently...
Fcα Receptor-1-Activated Monocytes Promote B Lymphocyte Migration and IgA Isotype Switching.
Amélie V Bos, Melissa MJ van Gool, Annelot C Breedveld, Richard van der Mast, Casper Marsman, Gerd Bouma, Mark A van de Wiel, S Marieke van Ham, Reina E Mebius, Marjolein van Egmond
Oct 06, 2022
The spatial signature of Plasmodium vivax and Plasmodium falciparum infections
Mirco Sandfort, Wuelton Monteiro, Marcus Lacerda, Wang Nguitragool, Jetsumon Sattabongkot, Andreea Waltmann, Henrik Salje, Amélie Vantaux, Benoit Witkowski, Leanne J Robinson, Ivo Mueller, Michael White
Mar 04, 2023
ERα-36 regulates progesterone receptor activity in breast cancer
Henri-Philippe Konan, Loay Kassem, Soleilmane Omarjee, Ausra Surmieliova-Garnès, Julien Jacquemetton, Elodie Cascales, Amélie Rezza, Olivier Trédan, Isabelle Treilleux, Coralie Poulard, Muriel Le Romancer
Jun 06, 2020
Abstract: Background: Alterations in estrogen and progesterone signaling, via their respective receptors, estrogen receptor alpha (ERα) and progesterone receptor (PR), respectively, are largely involved in the development of...
Leupaxin Expression Is Dispensable for B Cell Immune Responses
Amélie Bonaud, Simon Clare, Valeria Bisio, John M. Sowerby, Shugang Yao, Hanne Ostergaard, Karl Balabanian, Kenneth G. C. Smith, Marion Espéli
Apr 08, 2020
The generation of a potent humoral immune response by B cells relies on the integration of signals induced by the B cell receptor, toll-like receptors and both negative and positive co-receptors. Several reports also suggest...
Reassessment of the phylogenetic relationships of the late Miocene apes Hispanopithecus and Rudapithecus based on vestibular morphology.
Alessandro Urciuoli, Clément Zanolli, Sergio Almécija, Amélie Beaudet, Jean Dumoncel, Naoki Morimoto, Masato Nakatsukasa, Salvador Moyà-Solà, David R Begun, David M Alba
May 24, 2021
Late Miocene great apes are key to reconstructing the ancestral morphotype from which earliest hominins evolved. Despite consensus that the late Miocene dryopith great apes Hispanopithecus laietanus (Spain) and Rudapithecus...
StW 573 Australopithecus prometheus
Robin Huw Crompton, Juliet McClymont, Sarah Elton, Susannah Thorpe, William Sellers, Jason Heaton, Travis Rayne Pickering, Todd Pataky, Kristian J Carlson, Tea Jashashvili, Amélie Beaudet, Laurent Bruxelles, Ethan Goh, Kathleen Kuman, Ronald Clarke
Nov 16, 2021
The StW 573 skeleton of Australopithecus prometheus from Sterkfontein Member 2 is some 93% complete and thus by far the most complete member of that genus yet found. Firmly dated at 3.67 Ma, it is one of the earliest specimens...
Leupaxin Expression Is Dispensable for B Cell Immune Responses.
Amélie Bonaud, Simon Clare, Valeria Bisio, John M Sowerby, Shugang Yao, Hanne Ostergaard, Karl Balabanian, Kenneth G C Smith, Marion Espéli
May 10, 2020
The generation of a potent humoral immune response by B cells relies on the integration of signals induced by the B cell receptor, toll-like receptors and both negative and positive co-receptors. Several reports also suggest...
Published by: Frontiers in immunology
Cross-calibration of CO- versus dust-based gas masses and assessment of the <i>dynamical </i>mass budget in <i>Herschel</i>-SDSS Stripe82 galaxies
Caroline Bertemes, Stijn Wuyts, Dieter Lutz, Natascha M Förster schreiber, Reinhard Genzel, Robert F Minchin, Carole G Mundell, David Rosario, Amélie Saintonge, Linda Tacconi
Aug 01, 2018
We present a cross-calibration of CO- and dust-based molecular gas masses at z ≤ 0.2. Our results are based on a survey with the IRAM 30-m telescope collecting CO(1–0) measurements of 78 massive (logM⋆/M⊙> 10) galaxies with...
Cross-calibration of CO- versus dust-based gas masses and assessment of the <i>dynamical </i>mass budget in <i>Herschel</i>-SDSS Stripe82 galaxies
Caroline Bertemes, Stijn Wuyts, Dieter Lutz, Natascha M Förster schreiber, Reinhard Genzel, Robert F Minchin, Carole G Mundell, David Rosario, Amélie Saintonge, Linda Tacconi
Aug 01, 2018
We present a cross-calibration of CO- and dust-based molecular gas masses at z ≤ 0.2. Our results are based on a survey with the IRAM 30-m telescope collecting CO(1–0) measurements of 78 massive (logM⋆/M⊙> 10) galaxies with...
A rare human variant that disrupts GPR10 signalling causes weight gain in mice.
Fleur Talbot, Claire H Feetham, Jacek Mokrosiński, Katherine Lawler, Julia M Keogh, Elana Henning, Edson Mendes de Oliveira, Vikram Ayinampudi, Sadia Saeed, Amélie Bonnefond, Mohammed Arslan, Giles S H Yeo, Philippe Froguel, David A Bechtold, Antony Adamson, Neil Humphreys, Inês Barroso, Simon M Luckman, I Sadaf Farooqi
Apr 15, 2023
Animals Mice Transgenic Humans Mice obesity Weight Gain Receptors G-Protein-Coupled Signal Transduction Energy Metabolism
Published by: Nature Communications
Sex-specific impact of prenatal androgens on social brain default mode subsystems.
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