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Results: 197
Minimally invasive esophageal sponge cytology sampling is feasible in a Tanzanian community setting.
Daniel RS Middleton, Blandina T Mmbaga, Maria O'Donovan, Behnoush Abedi-Ardekani, Irene Debiram-Beecham, Gissela Nyakunga-Maro, Venance Maro, Martin Bromwich, Amini Daudi, Timothy Ngowi, Rehema Minde, Jackson Claver, Alex Mremi, Amos Mwasamwaja, Joachim Schüz, Rebecca C Fitzgerald, Valerie McCormack
Feb 16, 2021
Esophageal sponge cytology is an endoscopy alternative well accepted by patients with extensive data for accuracy in the context of adenocarcinoma. Few studies have assessed its feasibility in asymptomatic community members, and...
Correlated and geographically predictable Neanderthal and Denisovan legacies are difficult to reconcile with a simple model based on inter-breeding.
William Amos
Jul 28, 2021
Although the presence of archaic hominin legacies in humans is taken for granted, little attention has been given as to how the data fit with how humans colonized the world. Here, I show that Neanderthal and Denisovan legacies...
Signatures of Introgression across the Allele Frequency Spectrum.
The detection of introgression from genomic data is transforming our view of species and the origins of adaptive variation. Among the most widely used approaches to detect introgression is the so-called ABBA-BABA test or...
Flanking heterozygosity influences the relative probability of different base substitutions in humans.
William Amos
Nov 26, 2019
Understanding when, where and which mutations are mostly likely to occur impacts many areas of evolutionary biology, from genetic diseases to phylogenetic reconstruction. Africans and non-African humans differ in the mutability...
Classification of symmetry-protected topological many-body localized phases in one dimension.
We provide a classification of symmetry-protected topological (SPT) phases of many-body localized (MBL) spin and fermionic systems in one dimension. For spin systems, using tensor networks we show that all eigenstates of these...
Correlated and geographically predictable Neanderthal and Denisovan legacies are difficult to reconcile with a simple model based on inter-breeding
William Amos
Jun 17, 2021
Although the presence of archaic hominin legacies in humans is taken for granted, little attention has been given as to how the data fit with how humans colonized the world. Here, I show that Neanderthal and Denisovan legacies...
Resistance to Targeted Agents Used to Treat Paediatric ALK-Positive ALCL.
Non-Hodgkin lymphoma (NHL) is the third most common malignancy diagnosed in children. The vast majority of paediatric NHL are either Burkitt lymphoma (BL), diffuse large B-cell lymphoma (DLBCL), anaplastic large cell lymphoma...
Global demographic history of human populations inferred from whole mitochondrial genomes.
The Neolithic transition has led to marked increases in census population sizes across the world, as recorded by a rich archaeological record. However, previous attempts to detect such changes using genetic markers, especially...
Cranioplasty Following Decompressive Craniectomy
Corrado Iaccarino, Angelos G. Kolias, Louis-Georges Roumy, Kostas Fountas, Amos Olufemi Adeleye
Feb 12, 2020
Cranioplasty (CP) after decompressive craniectomy (DC) for trauma is a neurosurgical procedure that aims to restore esthesis, improve cerebrospinal fluid (CSF) dynamics, and provide cerebral protection. In turn, this can...
Prevention of radiotherapy-induced neurocognitive dysfunction in survivors of paediatric brain tumours
Neurocognitive dysfunction is the leading cause of reduced quality of life in long-term survivors of paediatric brain tumours. Radiotherapy is one of the main contributors to neurocognitive sequelae. Current approaches for...
The red edge excitation shift phenomenon can be used to unmask protein structural ensembles
To understand complex molecular interactions it is necessary to account for molecular flexibility and the available equilibrium of conformational states. Only a small number of experimental approaches can access such...
Evolution of the recombination regulator PRDM9 in minke whales.
Consanguinity and susceptibility to infectious diseases in humans.
Studies of animal populations suggest that low genetic heterozygosity is an important risk factor for infection by a diverse range of pathogens, but relatively little research has looked to see whether similar patterns exist in...
Women's appraisal, interpretation and help-seeking for possible symptoms of breast and cervical cancer in South Africa
BACKGROUND: In South Africa, breast cancer is the most commonly diagnosed cancer and cervical cancer the leading cause of cancer mortality. Most cancers are diagnosed at a late-stage and following symptomatic presentation. The...
Breast Cancer Cervical cancer Help-seeking Qualitative research methods South Africa symptom appraisal Adult Breast Neoplasms Cross-Sectional Studies Female Health Knowledge Attitudes practice Humans Middle Aged Patient Acceptance of Health Care qualitative research South Africa Uterine Cervical Neoplasms Young Adult
A System Dynamics Model of Technology and Society
Kenya has emerged in recent times as one of the fastest growing telecom markets in the world. There is not a single, widely used paradigm which has synthesised the various schools and theories dealing with technology and...
Published by: IGI Global Scientific Publishing
Users' Acceptance of Artificial Intelligence-Based Chatbots
This research examines the effects of factors such as perceived ease of use, perceived usefulness, perceived enjoyment, innovativeness, perceived information quality, and perceived customisation on behavioural intention to use...
Published by: IGI Global Scientific Publishing
Mechanisms of cell death induced by arginase and asparaginase in precursor B-cell lymphoblasts.
Arginase has therapeutic potential as a cytotoxic agent in some cancers, but this is unclear for precursor B acute lymphoblastic leukaemia (pre-B ALL), the commonest form of childhood leukaemia. We compared arginase cytotoxicity...
Cranioplasty Following Decompressive Craniectomy.
Corrado Iaccarino, Angelos G Kolias, Louis-Georges Roumy, Kostas Fountas, Amos Olufemi Adeleye
Mar 25, 2020
Cranioplasty (CP) after decompressive craniectomy (DC) for trauma is a neurosurgical procedure that aims to restore esthesis, improve cerebrospinal fluid (CSF) dynamics, and provide cerebral protection. In turn, this can...
The red edge excitation shift phenomenon can be used to unmask protein structural ensembles
To understand complex molecular interactions it is necessary to account for molecular flexibility and the available equilibrium of conformational states. Only a small number of experimental approaches can access such...
Social, demographic and healthcare factors associated with stage at diagnosis of cervical cancer
Amos Deogratius Mwaka, Christopher Orach Garimoi, Edward Maloba Were, Martin Roland, Henry Wabinga, Georgios Lyratzopoulos
Dec 02, 2015
Cervical cancer pathways to diagnosis and treatment predictors of late stage Adolescent Adult Age Factors Cross-Sectional Studies Delayed Diagnosis Developing Countries Educational Status Female Humans Marital Status Middle Aged Neoplasm Staging Parity Patient Acceptance of Health Care Pilot Projects Poverty Rural Population Tertiary Care Centers Uganda Uterine Cervical Neoplasms Young Adult
Understanding Factors Affecting E-Government Adoption in Saudi Arabia
Ahmed Almamy
Jan 01, 2022
This study developed an integrated model to examine the main factors affecting e-government services adoption in Saudi Arabia context. We extended the UTAUT model to explore factors affecting Saudi Arabia citizens to use...
Published by: IGI Global Scientific Publishing
An assessment of the rescue action of resveratrol in parkin loss of function-induced oxidative stress in Drosophila melanogaster.
Adeola O Adedara, Ayoade D Babalola, Flora Stephano, Ifeoluwa O Awogbindin, James O Olopade, João BT Rocha, Alexander J Whitworth, Amos O Abolaji
Mar 10, 2022
Loss-of-function mutations in parkin is associated with onset of juvenile Parkinson's disease (PD). Resveratrol is a polyphenolic stilbene with neuroprotective activity. Here, we evaluated the rescue action of resveratrol in...
From bench to bedside
Children's Oncology Group European Inter-Group for Childhood non-Hodgkin Lymphoma anaplastic large cell lymphoma Anaplastic Lymphoma Kinase anaplastic lymphoma kinase inhibitors Anaplastic Lymphoma Kinase Biomarkers Tumor Child Combined Modality Therapy Disease Management Humans Lymphoma Large-Cell Anaplastic Molecular Targeted Therapy Prognosis Protein Kinase Inhibitors Translational Research Biomedical Treatment Outcome
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