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Results: 16059
A case for a negative-strand coding sequence in a group of positive-sense RNA viruses.
Positive-sense single-stranded RNA viruses form the largest and most diverse group of eukaryote-infecting viruses. Their genomes comprise one or more segments of coding-sense RNA that function directly as messenger RNAs upon...
Metaverse!
This study aimed to synthesize the literature on Metaverse to highlight its current research, opportunities, and applications in e-healthcare and education to reduce inequalities and for delivering fair and equal opportunities...
Published by: IGI Global Scientific Publishing
A hidden gene in astroviruses encodes a viroporin
Abstract: Human astroviruses are small non-enveloped viruses with positive-sense single-stranded RNA genomes. Astroviruses cause acute gastroenteritis in children worldwide and have been associated with encephalitis and...
A hidden gene in astroviruses encodes a viroporin
Abstract: Human astroviruses are small non-enveloped viruses with positive-sense single-stranded RNA genomes. Astroviruses cause acute gastroenteritis in children worldwide and have been associated with encephalitis and...
Propensity of a picornavirus polymerase to slip on potyvirus-derived transcriptional slippage sites.
The substitution rates of viral polymerases have been studied extensively. However less is known about the tendency of these enzymes to 'slip' during RNA synthesis to produce progeny RNAs with nucleotide insertions or deletions....
Andrew Carnegie and the foundations of contemporary entrepreneurial philanthropy
This paper focuses upon the relationship between the business and philanthropic endeavours of world-making entrepreneurs; asking why, how and to what ends these individuals seek to extend their reach in society beyond...
Translational autoregulation of BZW1 and BZW2 expression by modulating the stringency of start codon selection.
The efficiency of start codon selection during ribosomal scanning in eukaryotic translation initiation is influenced by the context or flanking nucleotides surrounding the AUG codon. The levels of eukaryotic translation...
Identification of RNA virus-derived RdRp sequences in publicly available transcriptomic datasets.
RNA viruses are abundant, highly diverse, and infect all or most eukaryotic organisms. However, only a tiny fraction of the number and diversity of RNA virus species have been catalogued. To cost effectively expand the diversity...
CIAlign
BACKGROUND: Throughout biology, multiple sequence alignments (MSAs) form the basis of much investigation into biological features and relationships. These alignments are at the heart of many bioinformatics analyses. However...
E-e-e-e-asy Does It
Mark Y. Herring
Jan 01, 0001
Is it just my e-magination, or are we in an e-lust for e-books? E-verywhere I look, now, I seem to e-ncounter something about eBooks. I have been ebombarded recently with a glut of eBook offers.
Published by: Winthrop University
Perceived Barriers to Business-to-Government (B2G) E-Commerce Adoption
There are several studies that assess the influence of factors on citizens' intention to adopt e-government services in various contexts. However, there is a lack of research that examines the perceived barriers to B2G...
Published by: IGI Global Scientific Publishing
Andrew Carnegie and the foundations of contemporary entrepreneurial philanthropy
This paper focuses upon the relationship between the business and philanthropic endeavours of world-making entrepreneurs; asking why, how and to what ends these individuals seek to extend their reach in society beyond...
Transcriptional slippage in the positive-sense RNA virus family Potyviridae.
P3N‐PIPO Potyvirus RNA virus Gene Expression transcriptional slippage DNA-Directed RNA Polymerases Frameshifting Ribosomal Gene Expression Regulation Viral Genome Viral High-Throughput Nucleotide Sequencing Open Reading Frames Plant Leaves Potyvirus RNA Viral Tobacco Transcription Genetic Viral Proteins
Characterization of the stimulators of protein-directed ribosomal frameshifting in Theiler's murine encephalomyelitis virus.
Many viruses utilize programmed -1 ribosomal frameshifting (-1 PRF) to express additional proteins or to produce frameshift and non-frameshift protein products at a fixed stoichiometric ratio. PRF is also utilized in the...
Discovery of frameshifting in Alphavirus 6K resolves a 20-year enigma.
BACKGROUND: The genus Alphavirus includes several potentially lethal human viruses. Additionally, species such as Sindbis virus and Semliki Forest virus are important vectors for gene therapy, vaccination and cancer research...
Amino Acid Sequence Animals Base Sequence Cell Line Conserved Sequence Cricetinae Fluorescent Antibody Technique Frameshifting Ribosomal Gene Order Immunoprecipitation Isotope Labeling Mass Spectrometry Molecular Sequence Data Nucleic Acid Conformation RNA Viral Semliki forest virus Viral Structural Proteins Virion
A case for a negative-strand coding sequence in a group of positive-sense RNA viruses.
Positive-sense single-stranded RNA viruses form the largest and most diverse group of eukaryote-infecting viruses. Their genomes comprise one or more segments of coding-sense RNA that function directly as messenger RNAs upon...
Published by: Virus evolution
Developing A Holistic Approach For E-Learning Accessibility
The importance of accessibility to digital resources is now widely acknowledged. The W3C WAI has played a significant role in promoting the importance of accessibility and developing a framework for accessible Web resources. The...
Comparative Analysis of Gene Expression in Virulent and Attenuated Strains of Infectious Bronchitis Virus at Subcodon Resolution.
RNA virus RNASeq avian coronavirus differential gene expression ribosome profiling Translation Animals Chickens Codon Coronavirus Infections Frameshifting Ribosomal Gene Expression Gene Expression Profiling Gene Expression Regulation Viral Infectious bronchitis virus Open Reading Frames Poultry Diseases RNA Messenger RNA Viral Ribosomes Transcriptome Virulence Exome Sequencing
Evidence for a novel overlapping coding sequence in POLG initiated at a CUG start codon
Yousuf A. Khan, Irwin Jungreis, James C. Wright, Jonathan M. Mudge, Jyoti S. Choudhary, Andrew E. Firth, Manolis Kellis
Mar 06, 2021
Abstract: Background: POLG, located on nuclear chromosome 15, encodes the DNA polymerase γ(Pol γ). Pol γ is responsible for the replication and repair of mitochondrial DNA (mtDNA). Pol γ is the only DNA polymerase found in...
Effect of 5'UTR introns on gene expression in Arabidopsis thaliana.
BACKGROUND: The majority of introns in gene transcripts are found within the coding sequences (CDSs). A small but significant fraction of introns are also found to reside within the untranslated regions (5'UTRs and 3'UTRs) of...
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