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Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2.
Sadam Yaseen, Gregory Demopulos, Thomas Dudler, Munehisa Yabuki, Christi L Wood, W Jason Cummings, Larry W Tjoelker, Teizo Fujita, Steven Sacks, Peter Garred, Peter Andrew, Robert B Sim, Peter J Lachmann, Russell Wallis, Nicholas Lynch, Wilhelm J Schwaeble
Aug 05, 2019
All 3 activation pathways of complement-the classic pathway (CP), the alternative pathway, and the lectin pathway (LP)- converge into a common central event: the cleavage and activation of the abundant third complement...
Biochemical resolving power of fluorescence lifetime imaging
A deeper understanding of spatial resolution has led to innovations in microscopy and the disruption of biomedical research, as with super-resolution microscopy. To foster similar advances in time-resolved and spectral imaging...
Correction to
Jonathan M Lawton, Mariam Habib, Bingkui Ma, Roger A Brooks, Serena M Best, Andrew L Lewis, Neil Rushton, William Bonfield
Jun 11, 2018
The article "The effect of cationically modified phosphorylcholine polymers on human osteoblasts in vitro and their effect on bone formation in vivo", written by Jonathan M. Lawton, Mariam Habib, Bingkui Ma, Roger A. Brooks...
Gravity-capillary waves in reduced models for wave-structure interactions
This paper is concerned with steady-state subcritical gravity-capillary waves that are produced by potential flow past a wave-making body. Such flows are characterised by two non-dimensional parameters: the Froude number, and...
Gravity-capillary waves in reduced models for wave-structure interactions
This paper is concerned with steady-state subcritical gravity-capillary waves that are produced by potential flow past a wave-making body. Such flows are characterised by two non-dimensional parameters: the Froude number, and...
Biochemical resolving power of fluorescence lifetime imaging
A deeper understanding of spatial resolution has led to innovations in microscopy and the disruption of biomedical research, as with super-resolution microscopy. To foster similar advances in time-resolved and spectral imaging...
Published by: Biomedical optics express
Andrew Carnegie and the foundations of contemporary entrepreneurial philanthropy
This paper focuses upon the relationship between the business and philanthropic endeavours of world-making entrepreneurs; asking why, how and to what ends these individuals seek to extend their reach in society beyond...
Conrad Russell, Richard Cust, and Andrew Thrush, eds. King James VI/I and His English Parliaments. New York
David L Smith
May 08, 2019
This book is a revised and extended version of the six Trevelyan Lectures that Conrad Russell delivered at Cambridge University in the Lent Term of 1995. Between then and his death in October 2004, Russell developed the lectures...
Andrew Carnegie and the foundations of contemporary entrepreneurial philanthropy
This paper focuses upon the relationship between the business and philanthropic endeavours of world-making entrepreneurs; asking why, how and to what ends these individuals seek to extend their reach in society beyond...
Hydration and N-acetyl-l-cysteine alter the microstructure of human nail and bovine hoof
This work aimed to (a) characterize the microstructure and porosity of human nail and bovine hoof by mercury intrusion porosimetry and SEM image analysis, (b) study the effects of hydration and of N-acetyl-l-cysteine treatment...
Corinna PMG 655 (= P.Oxy. 2370) fr.1 l. 13 κόσμ[εισα λόγυ]ς
L Prauscello
May 02, 2017
0. Fr. 1 of P.Oxy. 2370 (= MP3
249; LDAB 573), published by Lobel in 1956, is so far the only papyrus
fragment among those extant in Boeotian dialect1
whose authorship can be securely ascribed to
Corinna thanks to the overlap...
Floer Simple Manifolds and L-Space Intervals
An oriented three-manifold with torus boundary admits either no L-space Dehn filling, a unique L-space filling, or an interval of L-space fillings. In the latter case, which we call “Floer simple,” we construct an invariant...
Hydration and N-acetyl-l-cysteine alter the microstructure of human nail and bovine hoof
This work aimed to (a) characterize the microstructure and porosity of human nail and bovine hoof by mercury intrusion porosimetry and SEM image analysis, (b) study the effects of hydration and of N-acetyl-l-cysteine treatment...
Eugene L. Opie, 1910
The Rockefeller University
Jan 01, 0001
Eugene L. Opie, M.D. Inflammation
Lecture delivered February 10th, 1910
Bacterial Infection inflammation reaction macrophage Lymphatic Vessels polynuclear leucocytes enzyme
Published by: J.B. Lippincott Company
L q -spectra of self-affine measures
Abstract: We study L q -spectra of planar self-affine measures generated by diagonal matrices. We introduce a new technique for constructing and understanding examples based on combinatorial estimates for the exponential growth...
S-2-Amino-4-cyanobutanoic acid (β-cyanomethyl-L-Ala) as an atom-efficient solubilising synthon for L-glutamine
Glutamine (Gln) is often a difficult amino acid to incorporate during solution-phase peptide synthesis, owing to poor solubility and unwanted dehydrations as side-reactions. Current approaches to solving these problems are...
Frank L. Horsfall, Jr., 1952
The Rockefeller University
Jan 01, 0001
Frank L. Horsfall, Jr. Experiments on chemical alteration of virus infections.
Lecture delivered November 20, 1952
Posted with permission
Published by: Academic Press Inc., Publishers
Rapid sensing of l-leucine by human and murine hypothalamic neurons
Nicholas Heeley, Peter Kirwan, Tamana Darwish, Marion Arnaud, Mark L Evans, Florian T Merkle, Frank Reimann, Fiona M Gribble, Clemence Blouet
Apr 05, 2018
OBJECTIVE: Dietary proteins are sensed by hypothalamic neurons and strongly influence multiple aspects of metabolic health, including appetite, weight gain, and adiposity. However, little is known about the mechanisms by which...
S-2-Amino-4-cyanobutanoic acid (β-cyanomethyl-L-Ala) as an atom-efficient solubilising synthon for L-glutamine
Glutamine (Gln) is often a difficult amino acid to incorporate during solution-phase peptide synthesis, owing to poor solubility and unwanted dehydrations as side-reactions. Current approaches to solving these problems are...
Microbial regulation of the L cell transcriptome.
Tulika Arora, Rozita Akrami, Ramona Pais, Linda Bergqvist, Bengt R Johansson, Thue W Schwartz, Frank Reimann, Fiona M Gribble, Fredrik Bäckhed
Apr 26, 2018
L cells are an important class of enteroendocrine cells secreting hormones such as glucagon like peptide-1 and peptide YY that have several metabolic and physiological effects. The gut is home to trillions of bacteria affecting...
Dr. Herman L. Frick Promotion
Winthrop News Service
Jan 01, 0001
Dr. Herman L. Frick, superintendent of Winthrop Training School, was named Director of Teacher Education and Graduate Study at Winthrop in October 1946 Dr. Frick worked at Winthrop from 1941 to 1949 except for 1944-1946 when he...
Winthrop College of Education Winthrop Training School Higher Education Teacher Education and Professional Development
Published by: Winthrop University
IPR Policy Brief - Extending working life
Andrew Weyman
Mar 01, 2013
Despite recently announced rises in the minimum age at which the State Pension is claimable, many people continue to leave the labour market before their State Pension age (SPA).
Indeed, although a significant...
Indeed, although a significant...
Published by: University of Bath
IPR Policy Brief - Extending working life
Andrew Weyman
Mar 01, 2013
Despite recently announced rises in the minimum age at which the State Pension is claimable, many people continue to leave the labour market before their State Pension age (SPA).
Indeed, although a significant...
Indeed, although a significant...
Published by: University of Bath
Experimental analysis of the V-Charge variable drive supercharger system on a 1.0 L GTDI engine
Bo Hu, Sam Akehurst, Andrew G.J. Lewis, Pengfei Lu, Darren Millwood, Colin Copeland, Edward Chappell, Andrew De Freitas, James Shawe, Dave Burtt
Mar 01, 2018
A compound charging system that pairs a turbocharger with a supercharger seems to be a potential trend for future passenger car gasoline engines, as the strength of both could be enhanced and the deficiencies of each could be...
Travel demand management policies
This research study investigates the travel demand management (TDM) strategies and solutions and associated policies through a case study of Singapore to gain knowledge and experiences, and to evaluate the potentials for policy...
Comprehensive framework Policy transfer Transferability Transport policy Travel demand management /dk/atira/pure/subjectarea/asjc/3300/3305 name=Geography, Planning and Development /dk/atira/pure/subjectarea/asjc/3300/3313 name=Transportation /dk/atira/pure/subjectarea/asjc/3300/3322 name=Urban Studies /dk/atira/pure/sustainabledevelopmentgoals/sustainable_cities_and_communities name=SDG 11 - Sustainable Cities and Communities
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