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Mislocalization of neuronal tau in the absence of tangle pathology in phosphomutant tau knockin mice.
Jonathan Gilley, Kunie Ando, Anjan Seereeram, Teresa Rodríguez-Martín, Amy M Pooler, Laura Sturdee, Brian H Anderton, Jean-Pierre Brion, Diane P Hanger, Michael P Coleman
Jun 18, 2018
Hyperphosphorylation and fibrillar aggregation of the microtubule-associated protein tau are key features of Alzheimer's disease and other tauopathies. To investigate the involvement of tau phosphorylation in the pathological...
Dual role of nanoparticles as drug carrier and drug.
Hirak Kumar Patra, Anjan Kr Dasgupta, Sounik Sarkar, Indranil Biswas, Arnab Chattopadhyay
Jul 31, 2019
The conventional chemotherapeutic agents used in the treatment of human malignancies are directed nonspecifically against both malignant and nonmalignant cells, often limiting their efficacy with having serious side effects....
The True Identity of Putative Tooth Alveoli in a Cenozoic Crown Bird, the Gastornithid Omorhamphus
All extant birds are toothless, and recent molecular evidence suggests that edentulism in extant birds is the product of a single evolutionary transition to toothlessness on the line to crown birds in the Cretaceous. However, a...
A transitional snake from the Late Cretaceous period of North America
Snakes are the most diverse group of lizards, but their origins and early evolution remain poorly understood owing to a lack of transitional forms. Several major issues remain outstanding, such as whether snakes originated in a...
A transitional snake from the Late Cretaceous period of North America
Snakes are the most diverse group of lizards, but their origins and early evolution remain poorly understood owing to a lack of transitional forms. Several major issues remain outstanding, such as whether snakes originated in a...
RETRACTED
This paper explores the dynamics of justification in the wake of a rumor outbreak on social media. Specifically, it examines the extent to which the five types of justification—descriptive argumentation, presumptive...
Published by: IGI Global Scientific Publishing
Complete Ichthyornis skull illuminates mosaic assembly of the avian head
Daniel Field, Michael Hanson, David Burnham, Laura Wilson, Kristopher Super, Dana Ehret, Jun Ebersole, Bhart-Anjan S Bhullar
May 03, 2018
The skull of living birds is greatly modified from the condition found in their dinosaurian antecedents. Bird skulls have an enlarged, toothless premaxillary beak and an intricate kinetic system that includes a mobile palate...
Forty new specimens of Ichthyornis provide unprecedented insight into the postcranial morphology of crownward stem group birds.
Juan Benito, Albert Chen, Laura E Wilson, Bhart-Anjan S Bhullar, David Burnham, Daniel J Field
Jan 22, 2023
Ichthyornis has long been recognized as a pivotally important fossil taxon for understanding the latest stages of the dinosaur-bird transition, but little significant new postcranial material has been brought to light since...
Complete Ichthyornis skull illuminates mosaic assembly of the avian head
Daniel Field, Michael Hanson, David Burnham, Laura Wilson, Kristopher Super, Dana Ehret, Jun Ebersole, Bhart-Anjan S Bhullar
May 03, 2018
The skull of living birds is greatly modified from the condition found in their dinosaurian antecedents. Bird skulls have an enlarged, toothless premaxillary beak and an intricate kinetic system that includes a mobile palate...
Visualizing the strongly reshaped skyrmion Hall effect in multilayer wire devices.
Anthony KC Tan, Pin Ho, James Lourembam, Lisen Huang, Hang Khume Tan, Cynthia JO Reichhardt, Charles Reichhardt, Anjan Soumyanarayanan
Aug 13, 2021
Magnetic skyrmions are nanoscale spin textures touted as next-generation computing elements. When subjected to lateral currents, skyrmions move at considerable speeds. Their topological charge results in an additional transverse...
Visualizing the strongly reshaped skyrmion Hall effect in multilayer wire devices
Anthony K. C. Tan, Pin Ho, James Lourembam, Lisen Huang, Hang Khume Tan, Cynthia J. O. Reichhardt, Charles Reichhardt, Anjan Soumyanarayanan
Jul 28, 2021
Abstract: Magnetic skyrmions are nanoscale spin textures touted as next-generation computing elements. When subjected to lateral currents, skyrmions move at considerable speeds. Their topological charge results in an additional...
The skull roof tracks the brain during the evolution and development of reptiles including birds
Matteo Fabbri, Nicolás Mongiardino Koch, Adam C. Pritchard, Michael Hanson, Eva Hoffman, Gabriel S. Bever, Amy M. Balanoff, Zachary S. Morris, Daniel Field, Jasmin Camacho, Timothy B. Rowe, Mark A. Norell, Roger M. Smith, Arhat Abzhanov, Bhart-Anjan S. Bhullar
Oct 01, 2017
Major transformations in brain size and proportions, such as the Enlargement of the brain during the evolution of birds, are
accompanied by profound modifications to the skull roof. However, the hypothesis of concerted...
accompanied by profound modifications to the skull roof. However, the hypothesis of concerted...
The skull roof tracks the brain during the evolution and development of reptiles including birds
Matteo Fabbri, Nicolás Mongiardino Koch, Adam C. Pritchard, Michael Hanson, Eva Hoffman, Gabriel S. Bever, Amy M. Balanoff, Zachary S. Morris, Daniel Field, Jasmin Camacho, Timothy B. Rowe, Mark A. Norell, Roger M. Smith, Arhat Abzhanov, Bhart-Anjan S. Bhullar
Oct 01, 2017
Major transformations in brain size and proportions, such as the Enlargement of the brain during the evolution of birds, are
accompanied by profound modifications to the skull roof. However, the hypothesis of concerted...
accompanied by profound modifications to the skull roof. However, the hypothesis of concerted...
Evaluation of a minimally invasive cell sampling device coupled with assessment of trefoil factor 3 expression for diagnosing Barrett's esophagus
Caryn S Ross-Innes, Irene Debiram-Beecham, Maria O'Donovan, Elaine Walker, Sibu Varghese, Pierre Lao-Sirieix, Laurence Lovat, Michael Griffin, Krish Ragunath, Rehan Haidry, Sarmed S Sami, Philip Kaye, Marco Novelli, Babett Disep, Richard Ostler, Benoit Aigret, Bernard V North, Pradeep Bhandari, Adam Haycock, Danielle Morris, Stephen Attwood, Anjan Dhar, Colin Rees, Matthew DD Rutter, Peter D Sasieni, Rebecca C Fitzgerald, BEST2 study group
Feb 05, 2020
BACKGROUND: Barrett's esophagus (BE) is a commonly undiagnosed condition that predisposes to esophageal adenocarcinoma. Routine endoscopic screening for BE is not recommended because of the burden this would impose on the health...
Risk stratification of Barrett's oesophagus using a non-endoscopic sampling method coupled with a biomarker panel
Caryn S Ross-Innes, Hamza Chettouh, Achilleas Achilleos, Nuria Galeano-Dalmau, Irene Debiram-Beecham, Shona MacRae, Petros Fessas, Elaine Walker, Sibu Varghese, Theodore Evan, Pierre S Lao-Sirieix, Maria O'Donovan, Shalini Malhotra, Marco Novelli, Babett Disep, Phillip V Kaye, Laurence B Lovat, Rehan Haidry, Michael Griffin, Krish Ragunath, Pradeep Bhandari, Adam Haycock, Danielle Morris, Stephen Attwood, Anjan Dhar, Colin Rees, Matt D Rutter, Richard Ostler, Benoit Aigret, Peter D Sasieni, Rebecca C Fitzgerald, BEST2 study group
Nov 01, 2016
The Bangladesh Risk of Acute Vascular Events (BRAVE) Study
Rajiv Chowdhury, Dewan S Alam, Ismail Ibrahim Fakir, Sheikh Daud Adnan, Aliya Naheed, Ishrat Tasmin, Md Mostafa Monower, Farzana Hossain, Fatema Mahjabin Hossain, Md Mostafizur Rahman, Sadia Afrin, Anjan Kumar Roy, Minara Akter, Sima Akter Sume, Ajoy Kumer Biswas, Lisa Pennells, Praveen Surendran, Robin D Young, Sarah A Spackman, Khaled Hasan, Eric Harshfield, Nasir Sheikh, Richard Houghton, Danish Saleheen, Joanna MM Howson, Adam S Butterworth, Cardiology Research Group, Rubhana Raqib, Abdulla Al Shafi Majumder, John Danesh, Emanuele Di Angelantonio
Jun 05, 2015
Tempo and Pattern of Avian Brain Size Evolution.
Daniel T Ksepka, Amy M Balanoff, N Adam Smith, Gabriel S Bever, Bhart-Anjan S Bhullar, Estelle Bourdon, Edward L Braun, J Gordon Burleigh, Julia A Clarke, Matthew W Colbert, Jeremy R Corfield, Federico J Degrange, Vanesa L De Pietri, Catherine M Early, Daniel J Field, Paul M Gignac, Maria Eugenia Leone Gold, Rebecca T Kimball, Soichiro Kawabe, Louis Lefebvre, Jesús Marugán-Lobón, Carrie S Mongle, Ashley Morhardt, Mark A Norell, Ryan C Ridgely, Ryan S Rothman, R Paul Scofield, Claudia P Tambussi, Christopher R Torres, Marcel van Tuinen, Stig A Walsh, Akinobu Watanabe, Lawrence M Witmer, Alexandra K Wright, Lindsay E Zanno, Erich D Jarvis, Jeroen B Smaers
Apr 28, 2020
Relative brain sizes in birds can rival those of primates, but large-scale patterns and drivers of avian brain evolution remain elusive. Here, we explore the evolution of the fundamental brain-body scaling relationship across...
Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus.
Claire Palles, Laura Chegwidden, Xinzhong Li, John M Findlay, Garry Farnham, Francesc Castro Giner, Maikel P Peppelenbosch, Michal Kovac, Claire L Adams, Hans Prenen, Sarah Briggs, Rebecca Harrison, Scott Sanders, David MacDonald, Chris Haigh, Art Tucker, Sharon Love, Manoj Nanji, John deCaestecker, David Ferry, Barrie Rathbone, Julie Hapeshi, Hugh Barr, Paul Moayyedi, Peter Watson, Barbara Zietek, Neera Maroo, Laura Gay, Tim Underwood, Lisa Boulter, Hugh McMurtry, David Monk, Praful Patel, Krish Ragunath, David Al Dulaimi, Iain Murray, Konrad Koss, Andrew Veitch, Nigel Trudgill, Chuka Nwokolo, Bjorn Rembacken, Paul Atherfold, Elaine Green, Yeng Ang, Ernst J Kuipers, Wu Chow, Stuart Paterson, Sudarshan Kadri, Ian Beales, Charles Grimley, Paul Mullins, Conrad Beckett, Mark Farrant, Andrew Dixon, Sean Kelly, Matthew Johnson, Shahjehan Wajed, Anjan Dhar, Elinor Sawyer, Rebecca Roylance, Lynn Onstad, Marilie D Gammon, Douglas A Corley, Nicholas J Shaheen, Nigel C Bird, Laura J Hardie, Brian J Reid, Weimin Ye, Geoffrey Liu, Yvonne Romero, Leslie Bernstein, Anna H Wu, Alan G Casson, Rebecca Fitzgerald, David C Whiteman, Harvey A Risch, David M Levine, Tom L Vaughan, Auke P Verhaar, Jan van den Brande, Eelke L Toxopeus, Manon C Spaander, Bas PL Wijnhoven, Luc JW van der Laan, Kausilia Krishnadath, Cisca Wijmenga, Gosia Trynka, Ross McManus, John V Reynolds, Jacintha O'Sullivan, Padraic MacMathuna, Sarah A McGarrigle, Dermot Kelleher, Severine Vermeire, Isabelle Cleynen, Raf Bisschops, Ian Tomlinson, Janusz Jankowski
Feb 05, 2020
BACKGROUND & AIMS: Barrett's esophagus (BE) increases the risk of esophageal adenocarcinoma (EAC). We found the risk to be BE has been associated with single nucleotide polymorphisms (SNPs) on chromosome 6p21 (within the HLA...
Thiopurine monotherapy is effective in ulcerative colitis but significantly less so in Crohn’s disease
Evangelos Stournaras, Wendi Qian, Apostolos Pappas, You Yi Hong, Rasha Shawky, UK IBD BioResource Investigators, Tim Raine, Miles Parkes, UK IBD BioResource Investigators, Tariq Ahmad, Nick Kennedy, Peter Irving, Natalie Prescott, Charlie Lees, John Mansfield, Chris Lamb, Jack Satsangi, Alison Simmons, Alisa Hart, Sreedhar Subramanian, Chris Probert, Richard Shenderey, Anton Gunasekera, Klaartje Bel Kok, Babur Javaid, Leena Sinha, Salil Singh, Cathryn Preston, Mark Jarvis, Ruth Penn, Anjan Dhar, Achuth Shenoy, Kath Phillis, Arabis Oglesby, Jude Tilbury, Glyn Scott, Joseph Collum, Martyn Carter, Jamie Barbour, John Gordon, John Ramage, Ganesh Sivagi, Phil Roberts, Monica Bose, Shaji Sebastian, Joy Wilkins, Paul Banim, Alexana Kent, Ajay Verma, Dawn Warren, Alan Wiles, Matthew Johnson, Konrad Koss, Chirag Oza, Khalid Elamin, Annette Woods, Bijay Baburajan, Chris MacDonald, Byron Theron, Mark Tremelling, Udi Shmueli, Roisin Bevan, Jimmy Limdi, Prakash Nair, Deven Vani, Stephen Lewis, Michelle Baker-Moffat, Gordon Moran, Simon McLaughlin, Aminda de Silva, John Beckly, Anew Cole, Charles Murray, Alan Lobo, Melissa Smith, Sanju Mathew, John Saunders, Helen Steed, Matthew Brookes, Juliette Loehry, Monira Rahman, Jeff Butterworth, Ajay Muddu, Katie Clark, Christian Selinger, Arvind Ramadas, John McLaughlin, Richard Pollok, Colin Rees, Simon Panter, David Hobday, Stephen Foley, Vinod Patel, Emma Wesley, Daniel Gavin, Cathryn Edwards, Stuart Bloom, Chuka Nwokolo, John deCaestecker, Mina Hanna, Albert Davies, Laura Hancock, Fraser Cummings, Subramaniam Ramakrishnan, Theresa Tindall, Jonathan Landy, Richard Appleby, Dan Sharpstone, Andy Li, Richard Keld, Lin Mear, Anne Philips, Horace Willia, Laura Hancock Ben Warner, Dharmaraj Durai, Elaine Brinkworth, Zahid Mahmood, Rachel Cooney
Oct 06, 2020
Objective: Thiopurines are widely used as maintenance therapy in inflammatory bowel disease (IBD) but the evidence base for their use is sparse and their role increasingly questioned. Using the largest series reported to date...