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Results: 151
Whole-blood expression of inflammasome- and glucocorticoid-related mRNAs correctly separates treatment-resistant depressed patients from drug-free and responsive patients in the BIODEP study
Annamaria Cattaneo, Clarissa Ferrari, Lorinda Turner, Nicole Mariani, Daniela Enache, Caitlin Hastings, Melisa Kose, Giulia Lombardo, Anna P. McLaughlin, Maria A. Nettis, Naghmeh Nikkheslat, Luca Sforzini, Courtney Worrell, Zuzanna Zajkowska, Nadia Cattane, Nicola Lopizzo, Monica Mazzelli, Linda Pointon, Philip J. Cowen, Jonathan Cavanagh, Neil A. Harrison, Peter de Boer, Declan Jones, Wayne C. Drevets, Valeria Mondelli, Edward T. Bullmore, Carmine M. Pariante
Jul 23, 2020
Whole-blood expression of inflammasome- and glucocorticoid-related mRNAs correctly separates treatment-resistant depressed patients from drug-free and responsive patients in the BIODEP study
Annamaria Cattaneo, Clarissa Ferrari, Lorinda Turner, Nicole Mariani, Daniela Enache, Caitlin Hastings, Melisa Kose, Giulia Lombardo, Anna P. McLaughlin, Maria A. Nettis, Naghmeh Nikkheslat, Luca Sforzini, Courtney Worrell, Zuzanna Zajkowska, Nadia Cattane, Nicola Lopizzo, Monica Mazzelli, Linda Pointon, Philip J. Cowen, Jonathan Cavanagh, Neil A. Harrison, Peter de Boer, Declan Jones, Wayne C. Drevets, Valeria Mondelli, Edward T. Bullmore, Carmine M. Pariante
Jul 28, 2021
Whole-blood expression of inflammasome- and glucocorticoid-related mRNAs correctly separates treatment-resistant depressed patients from drug-free and responsive patients in the BIODEP study
Annamaria Cattaneo, Clarissa Ferrari, Lorinda Turner, Nicole Mariani, Daniela Enache, Caitlin Hastings, Melisa Kose, Giulia Lombardo, Anna P. McLaughlin, Maria A. Nettis, Naghmeh Nikkheslat, Luca Sforzini, Courtney Worrell, Zuzanna Zajkowska, Nadia Cattane, Nicola Lopizzo, Monica Mazzelli, Linda Pointon, Philip J. Cowen, Jonathan Cavanagh, Neil A. Harrison, Peter de Boer, Declan Jones, Wayne C. Drevets, Valeria Mondelli, Edward T. Bullmore, Carmine M. Pariante
Oct 19, 2020
Whole-blood expression of inflammasome- and glucocorticoid-related mRNAs correctly separates treatment-resistant depressed patients from drug-free and responsive patients in the BIODEP study
Annamaria Cattaneo, Clarissa Ferrari, Lorinda Turner, Nicole Mariani, Daniela Enache, Caitlin Hastings, Melisa Kose, Giulia Lombardo, Anna P. McLaughlin, Maria A. Nettis, Naghmeh Nikkheslat, Luca Sforzini, Courtney Worrell, Zuzanna Zajkowska, Nadia Cattane, Nicola Lopizzo, Monica Mazzelli, Linda Pointon, Philip J. Cowen, Jonathan Cavanagh, Neil A. Harrison, Peter de Boer, Declan Jones, Wayne C. Drevets, Valeria Mondelli, Edward T. Bullmore, Carmine M. Pariante
Feb 09, 2021
Whole-blood expression of inflammasome- and glucocorticoid-related mRNAs correctly separates treatment-resistant depressed patients from drug-free and responsive patients in the BIODEP study
Annamaria Cattaneo, Clarissa Ferrari, Lorinda Turner, Nicole Mariani, Daniela Enache, Caitlin Hastings, Melisa Kose, Giulia Lombardo, Anna P. McLaughlin, Maria A. Nettis, Naghmeh Nikkheslat, Luca Sforzini, Courtney Worrell, Zuzanna Zajkowska, Nadia Cattane, Nicola Lopizzo, Monica Mazzelli, Linda Pointon, Philip J. Cowen, Jonathan Cavanagh, Neil A. Harrison, Peter de Boer, Declan Jones, Wayne C. Drevets, Valeria Mondelli, Edward T. Bullmore, Carmine M. Pariante
Oct 20, 2020
The mouse genome displays highly dynamic populations of KRAB-zinc finger protein genes and related genetic units.
Annamaria Kauzlaric, Gabriela Ecco, Marco Cassano, Julien Duc, Michael Imbeault, Didier Trono
Dec 12, 2019
KRAB-containing poly-zinc finger proteins (KZFPs) constitute the largest family of transcription factors encoded by mammalian genomes, and growing evidence indicates that they fulfill functions critical to both embryonic...
A continuous model of physiological prion aggregation suggests a role for Orb2 in gating long-term synaptic information.
The regulation of mRNA translation at the level of the synapse is believed to be fundamental in memory and learning at the cellular level. The family of cytoplasmic polyadenylation element binding (CPEB) proteins emerged as an...
Whole-blood expression of inflammasome- and glucocorticoid-related mRNAs correctly separates treatment-resistant depressed patients from drug-free and responsive patients in the BIODEP study.
Annamaria Cattaneo, Clarissa Ferrari, Lorinda Turner, Nicole Mariani, Daniela Enache, Caitlin Hastings, Melisa Kose, Giulia Lombardo, Anna P McLaughlin, Maria A Nettis, Naghmeh Nikkheslat, Luca Sforzini, Courtney Worrell, Zuzanna Zajkowska, Nadia Cattane, Nicola Lopizzo, Monica Mazzelli, Linda Pointon, Philip J Cowen, Jonathan Cavanagh, Neil A Harrison, Peter de Boer, Declan Jones, Wayne C Drevets, Valeria Mondelli, Edward T Bullmore, Neuroimmunology of Mood Disorders and Alzheimer’s Disease (NIMA) Consortium, Carmine M Pariante
Jun 01, 2020
Effects of immunomodulatory drugs on depressive symptoms
Gayle M. Wittenberg, Annie Stylianou, Yun Zhang, Yu Sun, Ashutosh Gupta, P. S. Jagannatha, Dai Wang, Benjamin Hsu, Mark E. Curran, Shahid Khan, Guang Chen, Edward T. Bullmore, Wayne C. Drevets, Petra E. Vértes, Rudolf Cardinal, Sylvia Richardson, Gwenael Leday, Tom Freeman, David Hume, Tim Regan, Zhaozong Wu, Carmine Pariante, Annamaria Cattaneo, Patricia Zunszain, Alessandra Borsini, Robert Stewart, David Chandran, Livia Carvalho, Joshua Bell, Luis Henrique Souza-Teodoro, Hugh Perry, Neil Harrison, Declan Jones, Robert B Henderson
Aug 18, 2020
Body structural and cellular aging of women with low socioeconomic status in Hungary
Dorina Annar, Piroska Feher, Anna Madarasi, Nicholas Mascie-Taylor, Anna Kekesi, Irina Kalabiska, Agota Muzsnai, Annamaria Zsakai
Aug 11, 2021
OBJECTIVES: The health status of an individual is determined not only by their genetic background but also by their physical environment, social environment and access and use of the health care system. The Roma are one of the...
Cinnamaldehyde hydrogenation using Au–Pd catalysts prepared by sol immobilisation
Stefano Cattaneo, Simon J Freakley, David J Morgan, Meenakshisundaram Sankar, Nikolaos Dimitratos, Graham J Hutchings
Mar 21, 2018
We report the catalytic performance of Au–Pd nanoparticles prepared via a sol immobilisation technique for the catalytic hydrogenation of cinnamaldehyde under mild reaction conditions. We synthesised a series of bimetallic Au–Pd...
Cinnamaldehyde hydrogenation using Au–Pd catalysts prepared by sol immobilisation
Stefano Cattaneo, Simon J Freakley, David J Morgan, Meenakshisundaram Sankar, Nikolaos Dimitratos, Graham J Hutchings
Mar 21, 2018
We report the catalytic performance of Au–Pd nanoparticles prepared via a sol immobilisation technique for the catalytic hydrogenation of cinnamaldehyde under mild reaction conditions. We synthesised a series of bimetallic Au–Pd...
Role of microstructure in the electron–hole interaction of hybrid lead halide perovskites
Giulia Grancini, Ajay Ram Srimath Kandada, Jarvist M. Frost, Alex J. Barker, Michele De Bastiani, Marina Gandini, Sergio Marras, Guglielmo Lanzani, Aron Walsh, Annamaria Petrozza
Oct 01, 2015
Organic–inorganic metal halide perovskites have demonstrated high power conversion efficiencies in solar cells and promising performance in a wide range of optoelectronic devices. The existence and stability of bound...
Tumor Necrosis Factor α Influences Phenotypic Plasticity and Promotes Epigenetic Changes in Human Basal Forebrain Cholinergic Neuroblasts.
Giulia Guarnieri, Erica Sarchielli, Paolo Comeglio, Erika Herrera-Puerta, Irene Piaceri, Benedetta Nacmias, Matteo Benelli, Gavin Kelsey, Mario Maggi, Pasquale Gallina, Gabriella Barbara Vannelli, Annamaria Morelli
Nov 09, 2020
TNFα is the main proinflammatory cytokine implicated in the pathogenesis of neurodegenerative disorders, but it also modulates physiological functions in both the developing and adult brain. In this study, we investigated a...
Alzheimer’s disease DNA Methylation NGF TNFα receptors ciliogenesis human fetal neurons Neurogenesis Neuroinflammation Nucleus basalis of Meynert Basal Forebrain basal nucleus of Meynert Cell Line Cholinergic Neurons DNA Methylation Epigenesis Genetic Humans Microtubule-Associated Proteins Nerve Tissue Proteins Neuronal Plasticity Receptors Nerve Growth Factor Receptors Tumor Necrosis Factor Type II Tumor Necrosis Factor-alpha whole genome sequencing
Synthesis of highly uniform and composition-controlled gold-palladium supported nanoparticles in continuous flow
Stefano Cattaneo, Sultan Althahban, Simon J. Freakley, Meenakshisundaram Sankar, Thomas Davies, Qian He, Nikolaos Dimitratos, Christopher J. Kiely, Graham J. Hutchings
May 07, 2019
The synthesis of supported bimetallic nanoparticles with well-defined size and compositional parameters has long been a challenge. Although batch colloidal methods are commonly used to pre-form metal nanoparticles with the...
Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds.
Jutta Zimmer, Eliana MC Tacconi, Cecilia Folio, Sophie Badie, Manuela Porru, Kerstin Klare, Manuela Tumiati, Enni Markkanen, Swagata Halder, Anderson Ryan, Stephen P Jackson, Kristijan Ramadan, Sergey G Kuznetsov, Annamaria Biroccio, Julian E Sale, Madalena Tarsounas
Jan 13, 2016
Aminoquinolines Animals Antineoplastic Agents BRCA1 Protein BRCA2 Protein Biomarkers Tumor Cell Proliferation DNA Breaks Double-Stranded Dose-Response Relationship Drug Drug Resistance Neoplasm G-Quadruplexes G2 Phase Cell Cycle Checkpoints HEK293 Cells Humans Intracellular Signaling Peptides and Proteins Mad2 Proteins Male Mice Nude Molecular Targeted Therapy Neoplasms Picolinic Acids Poly(ADP-ribose) Polymerase Inhibitors RNA Interference Telomere Time Factors Transfection Tumor Burden Tumor Suppressor p53-Binding Protein 1 Xenograft Model Antitumor Assays
Role of microstructure in the electron–hole interaction of hybrid lead halide perovskites
Giulia Grancini, Ajay Ram Srimath Kandada, Jarvist M. Frost, Alex J. Barker, Michele De Bastiani, Marina Gandini, Sergio Marras, Guglielmo Lanzani, Aron Walsh, Annamaria Petrozza
Oct 01, 2015
Organic–inorganic metal halide perovskites have demonstrated high power conversion efficiencies in solar cells and promising performance in a wide range of optoelectronic devices. The existence and stability of bound...
Synthesis of highly uniform and composition-controlled gold-palladium supported nanoparticles in continuous flow
Stefano Cattaneo, Sultan Althahban, Simon J. Freakley, Meenakshisundaram Sankar, Thomas Davies, Qian He, Nikolaos Dimitratos, Christopher J. Kiely, Graham J. Hutchings
May 07, 2019
The synthesis of supported bimetallic nanoparticles with well-defined size and compositional parameters has long been a challenge. Although batch colloidal methods are commonly used to pre-form metal nanoparticles with the...
Tumor Necrosis Factor α Influences Phenotypic Plasticity and Promotes Epigenetic Changes in Human Basal Forebrain Cholinergic Neuroblasts
Giulia Guarnieri, Erica Sarchielli, Paolo Comeglio, Erika Herrera-Puerta, Irene Piaceri, Benedetta Nacmias, Matteo Benelli, Gavin Kelsey, Mario Maggi, Pasquale Gallina, Gabriella Barbara Vannelli, Annamaria Morelli
Aug 26, 2020
TNFα is the main proinflammatory cytokine implicated in the pathogenesis of neurodegenerative disorders, but it also modulates physiological functions in both the developing and adult brain. In this study, we investigated a...
Polymers of Z α1-antitrypsin are secreted in cell models of disease.
Annamaria Fra, Francesca Cosmi, Adriana Ordoñez, Romina Berardelli, Juan Perez, Noemi A Guadagno, Luciano Corda, Stefan J Marciniak, David A Lomas, Elena Miranda
Feb 12, 2019
Assessment of antibody library diversity through next generation sequencing and technical error compensation
M Fantini, L Pandolfini, S Lisi, M Chirichella, I Arisi, M Terrigno, M Goracci, F Cremisi, A Cattaneo
Aug 18, 2017
MiR-211 is essential for adult cone photoreceptor maintenance and visual function.
Sara Barbato, Elena Marrocco, Daniela Intartaglia, Mariateresa Pizzo, Sabrina Asteriti, Federica Naso, Danila Falanga, Rajeshwari S Bhat, Nicola Meola, Annamaria Carissimo, Marianthi Karali, Haydn M Prosser, Lorenzo Cangiano, Enrico Maria Surace, Sandro Banfi, Ivan Conte
Apr 20, 2018
MicroRNAs (miRNAs) are key post-transcriptional regulators of gene expression that play an important role in the control of fundamental biological processes in both physiological and pathological conditions. Their function in...
Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance.
Eliana MC Tacconi, Sophie Badie, Giuliana De Gregoriis, Timo Reisländer, Xianning Lai, Manuela Porru, Cecilia Folio, John Moore, Arnaud Kopp, Júlia Baguña Torres, Deborah Sneddon, Marcus Green, Simon Dedic, Jonathan W Lee, Ankita Sati Batra, Oscar M Rueda, Alejandra Bruna, Carlo Leonetti, Carlos Caldas, Bart Cornelissen, Laurent Brino, Anderson Ryan, Annamaria Biroccio, Madalena Tarsounas
Jul 31, 2019
BRCA1 BRCA2 DNA damage responses alkylating agents cisplatin Animals BRCA1 Protein BRCA2 Protein Cell Line Tumor Chlorambucil Cricetinae Drug Delivery Systems Drug Resistance Neoplasm Humans Leukemia Lymphocytic Chronic B-Cell Male Mice Mice SCID Peroxisome Proliferator-Activated Receptors Phthalazines Piperazines Xenograft Model Antitumor Assays
Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL.
Maria Giovanna De Leo, Leopoldo Staiano, Mariella Vicinanza, Alessandro Luciani, Annamaria Carissimo, Margherita Mutarelli, Antonella Di Campli, Elena Polishchuk, Giuseppe Di Tullio, Valentina Morra, Elena Levtchenko, Francesca Oltrabella, Tobias Starborg, Michele Santoro, Diego di Bernardo, Olivier Devuyst, Martin Lowe, Diego L Medina, Andrea Ballabio, Maria Antonietta De Matteis
Sep 03, 2019
Phosphoinositides (PtdIns) control fundamental cell processes, and inherited defects of PtdIns kinases or phosphatases cause severe human diseases, including Lowe syndrome due to mutations in OCRL, which encodes a PtdIns(4,5)P2...
MiR-182-3p targets TRF2 and impairs tumor growth of triple-negative breast cancer.
Roberto Dinami, Luca Pompili, Eleonora Petti, Manuela Porru, Carmen D'Angelo, Serena Di Vito, Angela Rizzo, Virginia Campani, Giuseppe De Rosa, Alejandra Bruna, Violeta Serra, Miguel Mano, Mauro Giacca, Carlo Leonetti, Gennaro Ciliberto, Madalena Tarsounas, Antonella Stoppacciaro, Stefan Schoeftner, Annamaria Biroccio
Nov 25, 2022
The telomeric repeat-binding factor 2 (TRF2) is a telomere-capping protein that plays a key role in the maintenance of telomere structure and function. It is highly expressed in different cancer types, and it contributes to...
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