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Repeated daily restraint stress induces adaptive behavioural changes in both adult and juvenile mice
Chronic stress is known to be a risk factor for the development of depression and anxiety, disorders which often begin during adolescence. Restraint stress is a commonly used stressor in adult rodents, however the effects of...
Repeated daily restraint stress induces adaptive behavioural changes in both adult and juvenile mice
Chronic stress is known to be a risk factor for the development of depression and anxiety, disorders which often begin during adolescence. Restraint stress is a commonly used stressor in adult rodents, however the effects of...
Sequence-dependent attack on peptides by photoactivated platinum anticancer complexes.
Christopher A Wootton, Carlos Sanchez-Cano, Andrea F Lopez-Clavijo, Evyenia Shaili, Mark P Barrow, Peter J Sadler, Peter B O'Connor
Jun 27, 2019
Octahedral platinum(iv) complexes such as trans,trans,trans-[Pt(N3)2(OH)2(pyridine)2] (1) are stable in the dark, but potently cytotoxic to a range of cancer cells when activated by UVA or visible light, and active in vivo....
The role of radiology in anatomy teaching in UK medical schools
AIMS: To investigate the current use of radiology in anatomy teaching across the UK, and to determine the level of interest expressed in expanding its role in medical education. MATERIALS AND METHODS: A 22-question electronic...
Re: the role of radiology in anatomy teaching in UK medical schools
Sir – We thank Raja and colleagues1 for their interest in our article and share their enthusiasm for the integration of radiology in anatomy teaching. This is something that we feel passionate about. Two of our authors are...
Active pulmonary tuberculosis
Tuberculosis remains a major global health issue affecting all countries and age groups. Radiology plays a crucial role in the diagnosis and management of pulmonary tuberculosis (PTB). This review aims to improve understanding...
Active pulmonary tuberculosis
Tuberculosis remains a major global health issue affecting all countries and age groups. Radiology plays a crucial role in the diagnosis and management of pulmonary tuberculosis (PTB). This review aims to improve understanding...
Rapid screening of photoactivatable metallodrugs
Ruth J McQuitty, Sarah Unterkofler, Tijmen G Euser, Philip St J Russell, Peter J Sadler
Dec 11, 2017
We explore the efficacy of a hyphenated photonic crystal fibre microflow reactor - high-resolution mass spectrometer system as a method for screening the activity of potential new photoactivatable drugs. The use of light to...
The functions of the A1A2A3 domains in von Willebrand factor include multimerin 1 binding.
D'Andra N Parker, Subia Tasneem, Richard W Farndale, Dominique Bihan, J Evan Sadler, Silvie Sebastian, Philip G de Groot, Catherine PM Hayward
Apr 26, 2016
adhesion molecules collagens platelet glycoproteins von Willebrand factor Blood Platelets Blood Proteins Enzyme-Linked Immunosorbent Assay Humans In Vitro Techniques Microfluidic Analytical Techniques Mutant Proteins Platelet Activation Platelet Adhesiveness Platelet Glycoprotein GPIb-IX Complex Protein Binding Protein Domains Recombinant Proteins Ristocetin Surface Plasmon Resonance von Willebrand Factor
What underlies the difference between self-reported health and disability after stroke? A qualitative study in the UK.
Nahal Mavaddat, Euan Sadler, Lisa Lim, Kate Williams, Elizabeth Warburton, Ann Louise Kinmonth, Chris Mckevitt, Jonathan Mant
Oct 18, 2021
BACKGROUND: Levels of self-reported health do not always correlate with levels of physical disability in stroke survivors. We aimed to explore what underlies the difference between subjective self-reported health and objectively...
Workshop to identify critical windows of exposure for children's health
The work group on cardiovascular and endocrine effects was asked to review the current state of knowledge about children's windows of vulnerability to developmental toxicants and to recommend how that information may be used to...
The different faces of metastatic melanoma in the gastrointestinal tract
Abstract Melanoma is the most aggressive form of skin cancer, with tendency to spread to any organ of the human body, including the gastrointestinal tract (GIT). The diagnosis of metastases to the...
Eva Mendes Serrao, Ana Maria Costa, Sergio Ferreira, Victoria McMorran, Emma Cargill, Caroline Hough, Ashley S Shaw, Brent O’Carrigan, Christine A Parkinson, Pippa G Corrie, Timothy J Sadler
Oct 05, 2022
Provision and Perception of Physiotherapy in the Nonoperative Management of Degenerative Cervical Myelopathy (DCM)
Max B Butler, Oliver D Mowforth, Abdul Badran, Michelle Starkey, Timothy Boerger, Iwan Sadler, Julia Tabrah, Caroline Treanor, Lucy Cameron Grad Dip Phys, Sukhvinder Kalsi-Ryan, Rodney J Laing, Benjamin M Davies, Mark RN Kotter
Sep 04, 2020
STUDY DESIGN: Cross-sectional survey. OBJECTIVES: Degenerative cervical myelopathy (DCM) is a common syndrome of acquired spinal cord impairment caused by canal stenosis secondary to arthritic changes of the spine. International...
Perceptions of self-rated health among stroke survivors
N Mavaddat, E Sadler, L Lim, K Williams, E Warburton, AL Kinmonth, J Mant, J Burt, C McKevitt
May 29, 2018
How does the increase in eating difficulties according to the Development and Well-Being Assessment screening items relate to the population prevalence of eating disorders? An analysis of the 2017 Mental Health in Children and Young People survey.
Jessica O'Logbon, Tamsin Newlove-Delgado, Sally McManus, Frances Mathews, Suzanne Hill, Katharine Sadler, Tamsin Ford
Oct 24, 2022
The forgotten appearance of metastatic melanoma in the small bowel
Eva Mendes Serrao, Emily Joslin, Victoria McMorran, Caroline Hough, Cheryl Palmer, Sarah McDonald, Emma Cargill, Ashley S Shaw, Brent O’Carrigan, Christine A Parkinson, Pippa G Corrie, Timothy J Sadler
Jun 14, 2022
Abstract: Background: Melanoma is the most aggressive form of skin cancer, with a tendency to metastasise to any organ of the human body. While the most common body organs affected include liver, lungs, brain and soft tissues...
What underlies the difference between self-reported health and disability after stroke? A qualitative study in the UK.
Nahal Mavaddat, Euan Sadler, Lisa Lim, Kate Williams, Elizabeth Warburton, Ann Louise Kinmonth, Chris Mckevitt, Jonathan Mant
Sep 14, 2021
Background
Levels of self-reported health do not always correlate with levels of physical disability in stroke survivors. We aimed to explore what underlies the difference between subjective self-reported health and...
Published by: BMC neurology
In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer.
Ruthenium complexes offer the potential of reduced toxicity, a novel mechanism of action, non-cross resistance and a different spectrum of activity compared to platinum containing compounds. Thirteen novel ruthenium(II)...
ATP Binding Cassette Transporter Subfamily B Member 1 Animals Antimetabolites Antineoplastic Antineoplastic Agents Azacitidine Calcium Channel Blockers Carboplatin cisplatin Decitabine Drug Design Drug Resistance Multiple Drug Resistance Neoplasm Drug Screening Assays Antitumor Edetic Acid Female Humans Ligands Mice Mice Nude Neoplasm Proteins Organometallic Compounds Ovarian Neoplasms Ruthenium Compounds Structure-Activity Relationship Verapamil Xenograft Model Antitumor Assays
What underlies the difference between self-reported health and disability after stroke? A qualitative study in the UK
Nahal Mavaddat, Euan Sadler, Lisa Lim, Kate Williams, Elizabeth Warburton, Ann Louise Kinmonth, Chris Mckevitt, Jonathan Mant
Aug 13, 2021
The Ursinus Weekly, March 13, 1933
Men's debate teams have eventful week Weekly reporters talk to Bomberger's chairs Resume shows successful 1933 wrestling season Intra-mural wrestling tourney on Wed. and Thurs. Freshmen complete fairly successful court...
Ursinus College Collegeville Pennsylvania newspaper May Day pageant debate team YMCA YWCA Basketball wrestling cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Current provision of myelopathy education in medical schools in the UK
Oliver Mowforth, Benjamin Davies, Max Stewart, Sam Smith, Alice Willison, Shahzaib Ahmed, Michelle Starkey, Iwan Sadler, Ellen Sarewitz, Sybil Stacpoole, Mark Kotter
Jul 06, 2020
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