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Results: 239
Translational adaptation to heat stress is mediated by RNA 5-methylcytosine in Caenorhabditis elegans.
Isabela Cunha Navarro, Francesca Tuorto, David Jordan, Carine Legrand, Jonathan Price, Fabian Braukmann, Alan G Hendrick, Alper Akay, Annika Kotter, Mark Helm, Frank Lyko, Eric A Miska
Nov 12, 2020
Methylation of carbon-5 of cytosines (m5 C) is a post-transcriptional nucleotide modification of RNA found in all kingdoms of life. While individual m5 C-methyltransferases have been studied, the impact of the global cytosine-5...
Caenorhabditis elegans 5-Methylcytosine NSUN RNA modifications translation efficiency 5-Methylcytosine Adaptation Physiological Animals CRISPR-Cas Systems Caenorhabditis elegans Cytosine Gene Editing Heat-Shock Response Hot Temperature Leucine Methyltransferases Mitochondria Proline Protein Biosynthesis RNA RNA processing Post-Transcriptional Ribosomes
The Influence of the Sports Events Industry on Sichuan's Economic Growth
The sports industry occupies an important position in China's national economy, and the sports event industry is its core industry, and its role in regional economic development has received more and more attention from all...
Published by: IGI Global Scientific Publishing
Lessons from recruitment to an internet based survey for Degenerative Cervical Myelopathy
The Prevalence of Asymptomatic and Symptomatic Spinal Cord Compression on Magnetic Resonance Imaging
"I am not delusional!" Sensory dysaesthesia secondary to degenerative cervical myelopathy.
Degenerative cervical myelopathy (DCM) is the most common cause of adult spinal cord dysfunction, most classically presenting with a broad-based gait and clumsy hands. Limb sensory loss and paraesthesia are considered common...
The Value of Emotional Intelligence in Transformational Change
The article offers insight to the issues surrounding organizational change while discussing reasons for change failure, and the ways for managing the same. Topics include using team approach for initiating change, and the value...
organizational change management business planning Emotional Intelligence Interpersonal and Small Group Communication Leadership Studies
Published by: Harrisburg University of Science and Technology
Therapeutic Potential of Astrocyte Transplantation.
Cell transplantation is an attractive treatment strategy for a variety of brain disorders, as it promises to replenish lost functions and rejuvenate the brain. In particular, transplantation of astrocytes has come into light...
Research Inefficiency in Degenerative Cervical Myelopathy
STUDY DESIGN: Scoping review. OBJECTIVE: To describe activity, themes and trends in degenerative cervical myelopathy (DCM) research over the past 20 years with a view to considering DCM research inefficiency. METHODS: A...
Energetic substrate availability regulates synchronous activity in an excitatory neural network.
David S Tourigny, Muhammad Kaiser Abdul Karim, Rodrigo Echeveste, Mark RN Kotter, John S O'Neill
Oct 22, 2019
Neural networks are required to meet significant metabolic demands associated with performing sophisticated computational tasks in the brain. The necessity for efficient transmission of information imposes stringent constraints...
Degenerative Cervical Myelopathy and the Aging Spine
Degenerative Cervical Myelopathy (DCM) is the most common cause of spinal cord injury in the world, but despite this, there remains many areas of uncertainty regarding the management of the condition. This special issue was...
Quantitative analysis of medical students' and physicians' knowledge of degenerative cervical myelopathy.
OBJECTIVES: We have previously identified a delay in general practitioner (GP) referrals for patients with degenerative cervical myelopathy (DCM). The aim of this study was to evaluate whether an education gap existed for DCM...
Tackling Research Inefficiency in Degenerative Cervical Myelopathy
BACKGROUND: Degenerative cervical myelopathy (DCM) is widely accepted as the most common cause of adult myelopathy worldwide. Despite this, there is no specific term or diagnostic criteria in the International Classification of...
Therapeutic Potential of Astrocyte Transplantation.
Cell transplantation is an attractive treatment strategy for a variety of brain disorders, as it promises to replenish lost functions and rejuvenate the brain. In particular, transplantation of astrocytes has come into light...
Characterization of glucose-related metabolic pathways in differentiated rat oligodendrocyte lineage cells.
13C acetate Energy Metabolism Glucose Glycolysis Mitochondria Oligodendroglia pyruvate carboxylation Acetates Acetyl Coenzyme A Animals Carbon Radioisotopes Cells Cultured Citric Acid Cycle Cytosol Glucose Lactic Acid Malates Mitochondria Neural Stem Cells Oligodendroglia Oxaloacetic Acid pentose phosphate pathway Phosphoenolpyruvate Pyruvic Acid Radiopharmaceuticals Rats Sprague-Dawley
Assessment of degenerative cervical myelopathy differs between specialists and may influence time to diagnosis and clinical outcomes.
INTRODUCTION: Degenerative Cervical Myelopathy [DCM] often presents with non-specific symptoms and signs. It progresses insidiously and leads to permanent neurological dysfunction. Decompressive surgery can halt disease...
Characterization of glucose-related metabolic pathways in differentiated rat oligodendrocyte lineage cells
Ana Amaral Porem Amaral, Mussie G Hadera, Joana M Tavares, Mark Kotter, Ursula Sonnewald
Sep 03, 2015
The Pathophysiology of Degenerative Cervical Myelopathy and the Physiology of Recovery Following Decompression.
Farhana Akter, Xinming Yu, Xingping Qin, Shun Yao, Parisa Nikrouz, Yasir Ahmed Syed, Mark Kotter
Jul 31, 2020
Background: Degenerative cervical myelopathy (DCM), also known as cervical spondylotic myelopathy is the leading cause of spinal cord compression in adults. The mainstay of treatment is surgical decompression, which leads to...
Degenerative Cervical Myelopathy
Aria Nouri, Joseph S. Cheng, Benjamin Davies, Mark Kotter, Karl Schaller, Enrico Tessitore
Feb 19, 2020
Degenerative cervical myelopathy (DCM) is the most common cause of spinal cord injury in developed countries; its prevalence is increasing due to the ageing of the population. DCM causes neurological dysfunction and is a...
Succinate supplementation improves metabolic performance of mixed glial cell cultures with mitochondrial dysfunction
Mitochondrial dysfunction, the inability to efficiently utilise metabolic fuels and oxygen, contributes to pathological changes following traumatic spinal cord or traumatic brain injury (TBI). In the present study, we tested the...
Quantitative analysis of medical students’ and physicians’ knowledge of degenerative cervical myelopathy
Objectives: We have previously identified a delay in general practitioner (GP) referrals for patients with degenerative cervical myelopathy (DCM). The aim of this study was to evaluate whether an education gap existed for DCM...
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