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The Influence of the Sports Events Industry on Sichuan's Economic Growth
The sports industry occupies an important position in China's national economy, and the sports event industry is its core industry, and its role in regional economic development has received more and more attention from all...
Published by: IGI Global Scientific Publishing
Boosting care and knowledge about hereditary cancer
Janet R Vos, Lisette Giepmans, Claas Röhl, Nicoline Geverink, Nicoline Hoogerbrugge, ERN GENTURIS
Feb 07, 2020
Approximately 27-36 million patients in Europe have one of the ~ 5.000-8.000 known rare diseases. These patients often do not receive the care they need or they have a substantial delay from diagnosis to treatment. In March...
Cross border health care European Reference Network Genetic Hereditary cancer Rare Diseases Syndrome Clinical Competence Databases Factual Europe Genetic Predisposition to Disease Genetic Testing Humans Information Dissemination Information Services International Cooperation Medical Oncology Neoplastic Syndromes Hereditary Quality Improvement Rare Diseases Registries Remote Consultation Time-to-Treatment
Monitoring Ca2+ elevations in individual astrocytes upon local release of amyloid beta in acute brain slices.
Olga Tyurikova, Kaiyu Zheng, Annika Rings, Anna Drews, David Klenerman, Dmitri A Rusakov
May 29, 2018
The pathogenesis of Alzheimer's disease (AD) is thought to involve acute neurotoxic effects exerted by oligomeric forms of amyloid-β 1-42 (Aβ). Application of Aβ oligomers in physiological concentrations have been shown to...
amyloid beta Astroglia calcium imaging fluorescence lifetime imaging Hippocampus Amyloid beta-Peptides Animals Astrocytes Calcium cations Divalent Central Nervous System Agents Hippocampus Membrane Potentials Microscopy Fluorescence Neurons Patch-Clamp Techniques Peptide Fragments Rats Sprague-Dawley Single-Cell Analysis Tissue Culture Techniques
Smoking cessation for improving mental health
Gemma Taylor, Nicola Lindson, Amanda Farley, Andrea Leinberger-Jabari, Katherine Sawyer, Rebecca te Water Naudé, Annika Theodoulou, Naomi King, Chloe Burke, Paul Aveyard
Mar 09, 2021
Background
There is a common perception that smoking generally helps people to manage stress, and may be a form of 'self‐medication' in people with mental health conditions. However, there are biologically plausible reasons...
There is a common perception that smoking generally helps people to manage stress, and may be a form of 'self‐medication' in people with mental health conditions. However, there are biologically plausible reasons...
Identification and bioinformatic analysis of neprilysin and neprilysin-like metalloendopeptidases in Drosophila melanogaster.
Heiko Meyer, Annika Buhr, Patrick Callaerts, Ronja Schiemann, Mariana F Wolfner, Steven J Marygold
Jul 08, 2021
The neprilysin (M13) family of metalloendopeptidases comprises highly conserved ectoenzymes that cleave and thereby inactivate many physiologically relevant peptides in the extracellular space. Impaired neprilysin activity is...
Published by: MicroPubl Biol
Smoking cessation for improving mental health
Gemma Taylor, Nicola Lindson, Amanda Farley, Andrea Leinberger-Jabari, Katherine Sawyer, Rebecca te Water Naudé, Annika Theodoulou, Naomi King, Chloe Burke, Paul Aveyard
Mar 09, 2021
Background
There is a common perception that smoking generally helps people to manage stress, and may be a form of 'self‐medication' in people with mental health conditions. However, there are biologically plausible reasons...
There is a common perception that smoking generally helps people to manage stress, and may be a form of 'self‐medication' in people with mental health conditions. However, there are biologically plausible reasons...
Capillary-scale solid rebounds
Carlos A. Galeano-Rios, Radu Cimpeanu, Isabelle A. Bauman, Annika MacEwen, Paul A. Milewski, Daniel M. Harris
Apr 10, 2021
A millimetre-size superhydrophobic sphere impacting on the free surface of a quiescent bath can be propelled back into the air by capillary effects and dynamic fluid forces, whilst transferring part of its energy to the...
Is subarctic forest advance able to keep pace with climate change?
W Gareth Rees, Annika Hofgaard, Stéphane Boudreau, David M Cairns, Karen Harper, Steven Mamet, Ingrid Mathisen, Zuzanna Swirad, Olga Tutubalina
Apr 06, 2020
Charge accumulation kinetics in multi-redox molecular catalysts immobilised on TiO2.
Carlota Bozal-Ginesta, Camilo A Mesa, Annika Eisenschmidt, Laia Francàs, Ravi B Shankar, Daniel Antón-García, Julien Warnan, Janina Willkomm, Anna Reynal, Erwin Reisner, James R Durrant
Jul 28, 2021
Multi-redox catalysis requires the accumulation of more than one charge carrier and is crucial for solar energy conversion into fuels and valuable chemicals. In photo(electro)chemical systems, however, the necessary accumulation...
Capillary-scale solid rebounds
Carlos A. Galeano-Rios, Radu Cimpeanu, Isabelle A. Bauman, Annika MacEwen, Paul A. Milewski, Daniel M. Harris
Apr 10, 2021
A millimetre-size superhydrophobic sphere impacting on the free surface of a quiescent bath can be propelled back into the air by capillary effects and dynamic fluid forces, whilst transferring part of its energy to the...
Urban Foraging: A Ubiquitous Human Practice Overlooked by Urban Planners, Policy, and Research
Charlie M. Shackleton, Patrick T. Hurley, Annika C. Dahlberg, Marla R. Emery, Harini Nagendra
Jan 01, 0001
Although hardly noticed or formally recognized, urban foraging by humans probably occurs in all urban settings around the world. We draw from research in India, South Africa, Sweden, and the United States to demonstrate the...
actors benefits dynamics tenure urban foraging Urban spaces Environmental Studies Food Studies Nature and Society Relations sustainability Urban Studies and Planning
Published by: Ursinus College
Translational adaptation to heat stress is mediated by RNA 5-methylcytosine in Caenorhabditis elegans.
Isabela Cunha Navarro, Francesca Tuorto, David Jordan, Carine Legrand, Jonathan Price, Fabian Braukmann, Alan G Hendrick, Alper Akay, Annika Kotter, Mark Helm, Frank Lyko, Eric A Miska
Nov 12, 2020
Methylation of carbon-5 of cytosines (m5 C) is a post-transcriptional nucleotide modification of RNA found in all kingdoms of life. While individual m5 C-methyltransferases have been studied, the impact of the global cytosine-5...
Caenorhabditis elegans 5-Methylcytosine NSUN RNA modifications translation efficiency 5-Methylcytosine Adaptation Physiological Animals CRISPR-Cas Systems Caenorhabditis elegans Cytosine Gene Editing Heat-Shock Response Hot Temperature Leucine Methyltransferases Mitochondria Proline Protein Biosynthesis RNA RNA processing Post-Transcriptional Ribosomes
BA.2 and BA.5 omicron differ immunologically from both BA.1 omicron and pre-omicron variants.
Annika Rössler, Antonia Netzl, Ludwig Knabl, Helena Schäfer, Samuel H Wilks, David Bante, Barbara Falkensammer, Wegene Borena, Dorothee von Laer, Derek J Smith, Janine Kimpel
Dec 13, 2022
Several studies have shown that SARS-CoV-2 BA.1 omicron is an immune escape variant. Meanwhile, however, omicron BA.2 and BA.5 became dominant in many countries and replaced BA.1. As both have several mutations compared to BA.1...
BA.2 and BA.5 omicron differ immunologically from both BA.1 omicron and pre-omicron variants.
Annika Rössler, Antonia Netzl, Ludwig Knabl, Helena Schäfer, Samuel H Wilks, David Bante, Barbara Falkensammer, Wegene Borena, Dorothee von Laer, Derek J Smith, Janine Kimpel
Jan 21, 2023
Several studies have shown that SARS-CoV-2 BA.1 omicron is an immune escape variant. Meanwhile, however, omicron BA.2 and BA.5 became dominant in many countries and replaced BA.1. As both have several mutations compared to BA.1...
Seroprevalence of SARS-CoV-2 infection in the Tyrolean district of Schwaz at the time of the rapid mass vaccination in March 2021 following B.1.351-variant outbreak.
Peter Willeit, Janine Kimpel, Hannes Winner, Teresa Harthaller, Helena Schäfer, David Bante, Barbara Falkensammer, Annika Rössler, Lydia Riepler, Cornelia Ower, Magdalena Sacher, Dorothee von Laer, Wegene Borena
Sep 23, 2022
Elevated Plasma Levels of 3-Hydroxyisobutyric Acid Are Associated With Incident Type 2 Diabetes.
Adil Mardinoglu, Silvia Gogg, Luca A Lotta, Alena Stančáková, Annika Nerstedt, Jan Boren, Matthias Blüher, Ele Ferrannini, Claudia Langenberg, Nicholas J Wareham, Markku Laakso, Ulf Smith
Mar 02, 2018
Branched-chain amino acids (BCAAs) metabolite, 3-Hydroxyisobutyric acid (3-HIB) has been identified as a secreted mediator of endothelial cell fatty acid transport and insulin resistance (IR) using animal models. To identify if...
3-Hydroxyisobutyric acid (3-HIB) Branched-chain amino acids (BCAAs) Insulin Resistance Insulin Secretion T2D Adipose Tissue Amino Acids Branched-Chain Biological Transport Body Mass Index Diabetes mellitus Type 2 Endothelial Cells Fatty Acids Humans Hydroxybutyrates Incidence Metabolome Microvessels
Secreted Toxins From Staphylococcus aureus Strains Isolated From Keratinocyte Skin Cancers Mediate Pro-tumorigenic Inflammatory Responses in the Skin.
Annika Krueger, Julian Zaugg, Sarah Chisholm, Richard Linedale, Nancy Lachner, Siok Min Teoh, Zewen K Tuong, Samuel W Lukowski, Mark Morrison, H Peter Soyer, Philip Hugenholtz, Michelle M Hill, Ian H Frazer
Feb 08, 2022
Squamous cell carcinoma (SCC) is a common type of skin cancer that typically arises from premalignant precursor lesions named actinic keratoses (AK). Chronic inflammation is a well-known promoter of skin cancer progression. AK...
An astronomically dated record of Earth's climate and its predictability over the last 66 million years.
Thomas Westerhold, Norbert Marwan, Anna Joy Drury, Diederik Liebrand, Claudia Agnini, Eleni Anagnostou, James SK Barnet, Steven M Bohaty, David De Vleeschouwer, Fabio Florindo, Thomas Frederichs, David A Hodell, Ann E Holbourn, Dick Kroon, Vittoria Lauretano, Kate Littler, Lucas J Lourens, Mitchell Lyle, Heiko Pälike, Ursula Röhl, Jun Tian, Roy H Wilkens, Paul A Wilson, James C Zachos
Oct 06, 2020
Much of our understanding of Earth's past climate comes from the measurement of oxygen and carbon isotope variations in deep-sea benthic foraminifera. Yet, long intervals in existing records lack the temporal resolution and age...
The flavivirus polymerase NS5 regulates translation of viral genomic RNA.
Teodoro Fajardo, Thomas J Sanford, Harriet V Mears, Annika Jasper, Skye Storrie, Daniel S Mansur, Trevor R Sweeney
Apr 02, 2020
Automatic analysis (aa)
Rhodri Cusack, Alejandro Vicente-Grabovetsky, Daniel J Mitchell, Conor J Wild, Tibor Auer, Annika C Linke, Jonathan E Peelle
Jun 26, 2018
Recent years have seen neuroimaging data sets becoming richer, with larger cohorts of participants, a greater variety of acquisition techniques, and increasingly complex analyses. These advances have made data analysis pipelines...
A Swedish Genome-Wide Haplotype Association Analysis Identifies a Novel Breast Cancer Susceptibility Locus in 8p21.2 and Characterizes Three Loci on Chromosomes 10, 11 and 16.
Elin Barnekow, Wen Liu, Hafdis T Helgadottir, Kyriaki Michailidou, Joseph Dennis, Patrick Bryant, Jessada Thutkawkorapin, Camilla Wendt, Kamila Czene, Per Hall, Sara Margolin, Annika Lindblom
Mar 02, 2022
(1) Background: The heritability of breast cancer is partly explained but much of the genetic contribution remains to be identified. Haplotypes are often used as markers of ethnicity as they are preserved through generations. We...
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