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Results: 508
Amyloid-β and APOE genotype predict memory decline in cognitively unimpaired older individuals independently of Alzheimer's disease polygenic risk score.
Jori Tomassen, Anouk den Braber, Sven J van der Lee, Lianne M Reus, Elles Konijnenberg, Stephen F Carter, Maqsood Yaqub, Bart NM van Berckel, Lyduine E Collij, Dorret I Boomsma, Eco JC de Geus, Philip Scheltens, Karl Herholz, Betty M Tijms, Pieter Jelle Visser
Dec 15, 2022
BACKGROUND: What combination of risk factors for Alzheimer's disease (AD) are most predictive of cognitive decline in cognitively unimpaired individuals remains largely unclear. We studied associations between APOE genotype...
APOE genotype Amyloid-β cognitive decline Longitudinal design neuropsychology polygenic risk score Preclinical Alzheimer’s disease Female Humans Male Alzheimer Disease Amyloid beta-Peptides Cognitive Dysfunction Genotype Apolipoproteins E Memory Disorders Risk Factors Positron-Emission Tomography Apolipoprotein E4
Weitere Beobachtungen Über den Einfluss der Befruchtung und der Zahl der Zellkeme auf die Saurebildung im Ei
Jacques Loeb
Jan 01, 0001
Jacques Loeb. Weitere Beobachtungen Über den Einfluss der Befruchtung und der Zahl der Zellkeme auf die Saurebildung im Ei
Reprinted from Biochem. Z., vol.2 (1906): 34-42
Published by: Rockefeller University
Application of DEN refinement and automated model building to a difficult case of molecular-replacement phasing
Axel T Brunger, Debanu Das, Ashley M Deacon, Joanna Grant, Thomas C Terwilliger, Randy J Read, Paul D Adams, Michael Levitt, Gunnar F Schröder
May 11, 2020
Phasing by molecular replacement remains difficult for targets that are far from the search model or in situations where the crystal diffracts only weakly or to low resolution. Here, the process of determining and refining the...
Theologische Diskussion und Entscheidung auf Synoden
Thomas Graumann
Jan 18, 2016
Wie wird auf Synoden Theologie diskutiert und Rechtgläubigkeit definiert? Was macht Synoden zum geeigneten Instrument oder Forum dieses Bemühens? Oder sollte man synodale Zusammenkünfte nicht prinzipiell als Ereignisse...
The management of acute knee dislocations
PURPOSE: Great variety and controversies surround the management strategies of acute multiligament knee injuries (aMKLIs) and no established guidelines exist for resource-limited practices. The aim of this study was to compare...
Coincident relapsing polychondritis and IgG4-related disease
Relapsing polychondritis (RP) and immunoglobulin G4–related disease (IgG4-RD) are rare multi-organ immune-mediated diseases. Both can present with nonspecific symptoms of fatigue, weight loss, arthralgia, raised inflammatory...
Visual loss in giant cell arteritis 3 weeks after steroid initiation.
Giant cell arteritis (GCA) is the most common vasculitis in adults and blindness is a common complication if left untreated. Oral glucocorticoids are the mainstay of treatment and if started promptly, loss of vision can usually...
The EU, Environmental Law and Brexit
Während der bevorstehende Brexit, also der Austritt des Vereinigten Königreiches aus der Europäischen Union, in den meisten anderen Rechtsgebieten eine große Herausforderung darstellt, wurden die Folgen des Brexit für das...
A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration.
Tobias Strunz, Susette Lauwen, Christina Kiel, International AMD Genomics Consortium (IAMDGC), Anneke den Hollander, Bernhard HF Weber
Jan 30, 2021
Genome-wide association studies (GWAS) for late stage age-related macular degeneration (AMD) have identified 52 independent genetic variants with genome-wide significance at 34 genomic loci. Typically, such an approach rarely...
Place of death and end-of-life transitions experienced by very old people with differing cognitive status
Anouk J Perrels, Jane Fleming, Jun Zhao, Stephen Barclay, Morag Farquhar, Hilde M Buiting, Carol Brayne, Cambridge City over-75s Cohort (CC75C) study collaboration
Jun 14, 2019
BACKGROUND: Despite fast-growing 'older old' populations, 'place of care' trajectories for very old people approaching death with or without dementia are poorly described and understood. AIM: To explore end-of-life transitions...
80 and over COGNITIVE IMPAIRMENT Aged Delivery of Health Care Dementia Frail Elderly Homes for the Aged Nursing Homes Patient Transfer residential characteristics Terminal Care Aged 80 and over Cognition Disorders Cohort Studies Female Hospital Mortality Humans Male Nursing Homes Terminal Care Terminally Ill United Kingdom
The Grizzly, March 16, 2023
Layla Halterman, Marie Sykes, Tatiana Kent, Chase Portaro, Ava Compagnoni, Brian Tague, Katie Cressman
Jan 01, 0001
Dean Schneider to Leave Ursinus: Announcement Raises Questions for Many Faculty Members Maker's Club Promises Creative Fun for All Majors Anarchy at Ursinus? Meet the New President, Alisa Zenchenko '25 Softball Season Back...
Ursinus College Collegeville Pennsylvania newspaper Mark Schneider makerspaces vandalism Alisa Zenchenko student government softball Intramural Sports tennis cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The Lantern Vol. 12, No. 1, January 1944
Leonard Schwartzstein, Joan Wilmot, Elizabeth Jane Cassatt, Barbara Cooke, Helen Gorson, Catherine Fremont, Constance Johnson, Carl Baumann, Beverly Cloud, Henry K. Haines, Richard Hunter, Rosine Ilgenfritz
Jan 01, 0001
In the Den of the Titans Lass of Dimoch For One Gone West Tropical New Year Nightfall Hope From the Blue Christmas Shopping, a Retrospective Glance What Makes a Wing Lift? 201 Main Street Paradox Stabilizing...
Ursinus College Collegeville Pennsylvania Lantern Literary Magazine poetry fiction Creative Nonfiction Christmas Aerodynamics Trappe Henry Melchior Muhlenberg House jazz swing music Arts and Humanities Creative Writing fiction illustration Nonfiction poetry
Published by: Ursinus College
A Neural Network Approach to Identify the Peritumoral Invasive Areas in Glioblastoma Patients by Using MR Radiomics
Jiun-Lin Yan, Chao Li, Anouk van der Hoorn, Natalie R. Boonzaier, Tomasz Matys, Stephen J. Price
Jun 17, 2021
Abstract: The challenge in the treatment of glioblastoma is the failure to identify the cancer invasive area outside the contrast-enhancing tumour which leads to the high local progression rate. Our study aims to identify its...
Hans Asperger: Held oder Bösewicht
Sarah Wonsidler
Jan 01, 0001
Hans Asperger war ein österreichischer Kinderarzt, Professor, und medizinischer Theoretiker bekannt für seinen Forschung über Autismus in Kindern. W?hrend des Zweiten Welt Kriegs und des Aufstiegs des Nationalsozialisus in Wien...
Hans Asperger Autismus sozialer Darwinismus Eugenik Bewegung am Spiegelgrund Herwig Czech Edith Scheffer Arts and Humanities European History German Language and Literature Holocaust and Genocide Studies Other Medical Sciences
Published by: Ursinus College
A Neural Network Approach to Identify the Peritumoral Invasive Areas in Glioblastoma Patients by Using MR Radiomics
Jiun-Lin Yan, Chao Li, Anouk van der Hoorn, Natalie R. Boonzaier, Tomasz Matys, Stephen J. Price
Aug 11, 2020
Abstract: The challenge in the treatment of glioblastoma is the failure to identify the cancer invasive area outside the contrast-enhancing tumour which leads to the high local progression rate. Our study aims to identify its...
The Grizzly, April 15, 1983
Perry Romer, Brad James, Rosemary Naab, Rosemary J. Wuenschel, Richard P. Richter, Sara D. Seese, Alison K. Brown, David Evans, Timothy Cosgrave, John Doyle, Ed Novick, James Tursi
Jan 01, 0001
Second Attack: Improvements Sought for Security New Senior Fund Seminar Planned The A's Come to Helfferich Hall Letter to the Editor: Most Abominable Act Faculty Promotions Approved President's Corner Sexual Assault in...
Ursinus College Collegeville Pennsylvania newspaper sexual assault scholarship fund economics seminar The A's Philadelphia Orchestra Model United Nations High Road to China Beach Boys baseball track team tennis lacrosse cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The draft genome of Ditylenchus dipsaci.
Benjamin Mimee, Etienne Lord, Pierre-Yves Véronneau, Rick Masonbrink, Qing Yu, Sebastian Eves-van den Akker
Jul 16, 2020
Ditylenchus dipsaci is a devastating pest to many crops worldwide. We present the first genome sequence for this species, produced with PacBio sequencing and assembled with CANU. Ditylenchus dipsaci is a devastating pest to many...
The Grizzly, October 24, 2013
Sabrina McGettigan, David Rogers, Bethany Mitchell, Deana Harley, Nicholas DiMuzio, Vivek Reddy, Shawn Hartigan, Brandon Patterson, Adebayo Adeyemo, Dom Roher, Briana Mullan, Mary Deliberti, Derrick Falletta, Austin Fox, James Wilson
Jan 01, 0001
Ursinus Receives Largest Private Donation in History Parking at Ursinus History Department Takes Students to Gettysburg Pennsylvania Senator Rafferty and Representative Vereb Speak in Bear's Den UC Students Volunteer to...
Ursinus College Collegeville Pennsylvania newspaper John F. Rodenbaugh James L. Boswell Parking Homecoming Ross Doughty Dallett Hemphill Mike Vereb John Rafferty Perkiomen Watershed Conservancy Lynnewood Hall sustainability Holly Hubbs Berman Art Museum campus safety Reimert Hall Anahi McIntyre Volleyball Soccer Football field hockey cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Anouk van der Hoorn, Jiun-Lin Yan, Timothy J Larkin, Natalie R Boonzaier, Tomasz Matys, Stephen J Price
May 12, 2016
Apparent diffusion coefficient Brain tumor Glioblastoma Magnetic Resonance Imaging treatment response Aged Brain Neoplasms Cohort Studies Diffusion Magnetic Resonance Imaging Female Glioblastoma Humans Image Processing Computer-Assisted Male Middle Aged Neoplasm Recurrence Local Regression Analysis Survival Analysis Treatment Outcome Tumor Burden
Validation of a semi-automatic co-registration of MRI scans in patients with brain tumors during treatment follow-up.
Anouk van der Hoorn, Jiun-Lin Yan, Timothy J Larkin, Natalie R Boonzaier, Tomasz Matys, Stephen J Price
Apr 01, 2016
MRI brain tumors high-grade gliomas linear co-registration non-linear co-registration structural similarity treatment response validation Adult Aged Algorithms Brain Neoplasms Female Follow-Up Studies Glioblastoma Humans Image Enhancement Image Interpretation Computer-Assisted Longitudinal Studies Magnetic Resonance Imaging Male Middle Aged pattern recognition Automated Sensitivity and Specificity Subtraction Technique Treatment Outcome
Ventricle contact is associated with lower survival and increased peritumoral perfusion in glioblastoma.
Bart Roelf Jan van Dijken, Peter Jan van Laar, Chao Li, Jiun-Lin Yan, Natalie Rosella Boonzaier, Stephen John Price, FCRS, Anouk van der Hoorn
Sep 05, 2018
5-ALA = 5-aminolevulinic acid ADC = apparent diffusion coefficient DWI = diffusion-weighted imaging FLAIR = fluid-attenuated inversion recovery FOV = field of view GBM = glioblastoma IDH = isocitrate dehydrogenase MGMT = O6-methylguanine-DNA-methyltransferase PWI = perfusion-weighted imaging RANO = Response Assessment in Neuro-Oncology SVZ = subventricular zone TE = echo time TI = inversion time TR = repetition time Glioblastoma Lateral Ventricles Magnetic Resonance Imaging oncology Perfusion rCBV = relative cerebral blood volume survival Adult Aged Brain Neoplasms Cerebral Ventricles Cerebrovascular Circulation Cohort Studies Female Glioblastoma Humans Magnetic Resonance Imaging Male Middle Aged Multimodal Imaging Survival Rate Treatment Outcome Young Adult
A Neural Network Approach to Identify the Peritumoral Invasive Areas in Glioblastoma Patients by Using MR Radiomics
Jiun-Lin Yan, Chao Li, Anouk van der Hoorn, Natalie R. Boonzaier, Tomasz Matys, Stephen J. Price
Jun 16, 2020
Abstract: The challenge in the treatment of glioblastoma is the failure to identify the cancer invasive area outside the contrast-enhancing tumour which leads to the high local progression rate. Our study aims to identify its...
A Neural Network Approach to Identify the Peritumoral Invasive Areas in Glioblastoma Patients by Using MR Radiomics.
Jiun-Lin Yan, Chao Li, Anouk van der Hoorn, Natalie R Boonzaier, Tomasz Matys, Stephen J Price
Jul 02, 2020
The challenge in the treatment of glioblastoma is the failure to identify the cancer invasive area outside the contrast-enhancing tumour which leads to the high local progression rate. Our study aims to identify its progression...
Adult Aged Aminolevulinic Acid Brain Neoplasms Cohort Studies Contrast Media Diffusion Magnetic Resonance Imaging Disease Progression Female Glioblastoma Humans Image Processing Computer-Assisted Magnetic Resonance Imaging Magnetic Resonance Spectroscopy Male Middle Aged Neural Networks Computer Optical Imaging Retrospective Studies
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