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Results: 6
Solvent exposure of Tyr10 as a probe of structural differences between monomeric and aggregated forms of the amyloid-β peptide.
Pablo Aran Terol, Janet R Kumita, Sharon C Hook, Christopher M Dobson, Elin K Esbjörner
Nov 11, 2015
Metabolomics Fingerprint Induced by the Intranigral Inoculation of Exogenous Human Alpha-Synuclein Oligomers in a Rat Model of Parkinson's Disease.
Federica Murgia, Luigi Atzori, Ezio Carboni, Maria Laura Santoru, Aran Hendren, Augusta Pisanu, Pierluigi Caboni, Laura Boi, Giuliana Fusco, Anna R Carta
Sep 15, 2020
Parkinson's disease (PD) is considered a synucleinopathy because of the intraneuronal accumulation of aggregated α-synuclein (αSyn). Recent evidence points to soluble αSyn-oligomers (αSynO) as the main cytotoxic species...
Parkinson model Biomarkers gas chromatography mass spectrometry mesencephalic tissue Metabolomics serum α-synuclein oligomers Animals Biomarkers Corpus Striatum Disease Models Animal Dopamine Humans Male Metabolome Metabolomics Neurons Oxidative Stress Parkinson Disease Rats Rats Sprague-Dawley Substantia Nigra ALPHA-SYNUCLEIN
Mitochondrial PITRM1 peptidase loss-of-function in childhood cerebellar atrophy.
Yeshaya Langer, Adi Aran, Suleyman Gulsuner, Bassam Abu Libdeh, Paul Renbaum, Dario Brunetti, Pedro-Filipe Teixeira, Tom Walsh, Sharon Zeligson, Roberta Ruotolo, Rachel Beeri, Imad Dweikat, Maher Shahrour, Ariella Weinberg-Shukron, Fouad Zahdeh, Enrico Baruffini, Elzbieta Glaser, Mary-Claire King, Ephrat Levy-Lahad, Massimo Zeviani, Reeval Segel
Nov 21, 2018
OBJECTIVE: To identify the genetic basis of a childhood-onset syndrome of variable severity characterised by progressive spinocerebellar ataxia, mental retardation, psychotic episodes and cerebellar atrophy. METHODS...
PITML cerebellar atrophy Mitochondria Next generation sequencing Whole exome sequencing Adolescent Age of Onset Arabs Atrophy Cerebellar Diseases cerebellum Child Humans Loss of Function Mutation Male Metalloendopeptidases Mitochondria Mitochondrial Proteins Pedigree Exome Sequencing whole genome sequencing Young Adult
How Reproducible are Surface Areas Calculated from the BET Equation?
Johannes WM Osterrieth, James Rampersad, David Madden, Nakul Rampal, Luka Skoric, Bethany Connolly, Mark D Allendorf, Vitalie Stavila, Jonathan L Snider, Rob Ameloot, João Marreiros, Conchi Ania, Diana Azevedo, Enrique Vilarrasa-Garcia, Bianca F Santos, Xian-He Bu, Ze Chang, Hana Bunzen, Neil R Champness, Sarah L Griffin, Banglin Chen, Rui-Biao Lin, Benoit Coasne, Seth Cohen, Jessica C Moreton, Yamil J Colón, Linjiang Chen, Rob Clowes, François-Xavier Coudert, Yong Cui, Bang Hou, Deanna M D'Alessandro, Patrick W Doheny, Mircea Dincă, Chenyue Sun, Christian Doonan, Michael Thomas Huxley, Jack D Evans, Paolo Falcaro, Raffaele Ricco, Omar Farha, Karam B Idrees, Timur Islamoglu, Pingyun Feng, Huajun Yang, Ross S Forgan, Dominic Bara, Shuhei Furukawa, Eli Sanchez, Jorge Gascon, Selvedin Telalović, Sujit K Ghosh, Soumya Mukherjee, Matthew R Hill, Muhammed Munir Sadiq, Patricia Horcajada, Pablo Salcedo-Abraira, Katsumi Kaneko, Radovan Kukobat, Jeff Kenvin, Seda Keskin, Susumu Kitagawa, Ken-Ichi Otake, Ryan P Lively, Stephen JA DeWitt, Phillip Llewellyn, Bettina V Lotsch, Sebastian T Emmerling, Alexander M Pütz, Carlos Martí-Gastaldo, Natalia M Padial, Javier García-Martínez, Noemi Linares, Daniel Maspoch, Jose A Suárez Del Pino, Peyman Moghadam, Rama Oktavian, Russel E Morris, Paul S Wheatley, Jorge Navarro, Camille Petit, David Danaci, Matthew J Rosseinsky, Alexandros P Katsoulidis, Martin Schröder, Xue Han, Sihai Yang, Christian Serre, Georges Mouchaham, David S Sholl, Raghuram Thyagarajan, Daniel Siderius, Randall Q Snurr, Rebecca B Goncalves, Shane Telfer, Seok J Lee, Valeska P Ting, Jemma L Rowlandson, Takashi Uemura, Tomoya Iiyuka, Monique A van der Veen, Davide Rega, Veronique Van Speybroeck, Sven MJ Rogge, Aran Lamaire, Krista S Walton, Lukas W Bingel, Stefan Wuttke, Jacopo Andreo, Omar Yaghi, Bing Zhang, Cafer T Yavuz, Thien S Nguyen, Felix Zamora, Carmen Montoro, Hongcai Zhou, Angelo Kirchon, David Fairen-Jimenez
May 23, 2022