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Results: 65
Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.
Kapil Gupta, Aleksandra A Watson, Tiago Baptista, Elisabeth Scheer, Anna L Chambers, Christine Koehler, Juan Zou, Ima Obong-Ebong, Eaazhisai Kandiah, Arturo Temblador, Adam Round, Eric Forest, Petr Man, Christoph Bieniossek, Ernest D Laue, Edward A Lemke, Juri Rappsilber, Carol V Robinson, Didier Devys, Làszlò Tora, Imre Berger
Jan 24, 2018
General transcription factor TFIID is a key component of RNA polymerase II transcription initiation. Human TFIID is a megadalton-sized complex comprising TATA-binding protein (TBP) and 13 TBP-associated factors (TAFs). TBP binds...
S. cerevisiae TBP associated factors TFIID Biochemistry biophysics core promoter DNA Gene regulation histone fold domain human structural biology Transcription Factors Crystallography X-Ray DNA Histone Acetyltransferases Humans Mass Spectrometry Promoter Regions Genetic Protein Binding Protein Conformation Protein Interaction Mapping TATA-Binding Protein Associated Factors TATA-Box Binding Protein Transcription Factor TFIID
Radial Glia and the Migration of Young Neurons in the Adult Avian Brain
Arturo Alvarez-Buylla
Jan 01, 0001
The adult bird brain continues to produce new neurons and integrate them into functional circuits. These cells are born in the ventricular zone (VZ) of the lateral ventricle, sometimes up to 5-6 mm away from the location were...
Published by: Rockefeller University
Reverse engineering of ceramic anthropomorphic figurines from the Tumaco archaeological tradition in southwest Colombia.
Traditional studies of archaeological ceramics in Colombia have been largely based on visual and stylistic analyses. Here we introduce frameworks and concepts of reverse engineering as a complementary strategy to develop...
Reverse engineering of ceramic anthropomorphic figurines from the Tumaco archaeological tradition in southwest Colombia.
Traditional studies of archaeological ceramics in Colombia have been largely based on visual and stylistic analyses. Here we introduce frameworks and concepts of reverse engineering as a complementary strategy to develop...
Published by: PLOS ONE
The heterochromatic chromosome caps in great apes impact telomere metabolism.
Clara Novo, Nausica Arnoult, Win-Yan Bordes, Luis Castro-Vega, Anne Gibaud, Bernard Dutrillaux, Silvia Bacchetti, Arturo Londoño-Vallejo
Jun 28, 2019
In contrast with the limited sequence divergence accumulated after separation of higher primate lineages, marked cytogenetic variation has been associated with the genome evolution in these species. Studying the impact of such...
Allergic disease, corticosteroid use, and risk of Hodgkin lymphoma
Meena Rafiq, Andrew Hayward, Charlotte Warren-Gash, Spiros Denaxas, Arturo Gonzalez-Izquierdo, Georgios Lyratzopoulos, Sara Thomas
Feb 07, 2020
BACKGROUND: Immunodeficiency syndromes (acquired/congenital/iatrogenic) are known to increase Hodgkin lymphoma (HL) risk, but the effects of allergic immune dysregulation and corticosteroids are poorly understood. OBJECTIVE: We...
allergic disease Hodgkin lymphoma allergic rhinitis Asthma Atopic dermatitis corticosteroids eczema risk Adolescent Adrenal Cortex Hormones Adult Case-Control Studies Child Child Preschool Female Hodgkin Disease Humans Hypersensitivity Immediate Immunocompromised Host Immunosuppressive Agents Male United Kingdom Young Adult
Adult neural stem cells in distinct microdomains generate previously unknown interneuron types.
Florian T Merkle, Luis C Fuentealba, Timothy A Sanders, Lorenza Magno, Nicoletta Kessaris, Arturo Alvarez-Buylla
Oct 14, 2020
Throughout life, neural stem cells (NSCs) in different domains of the ventricular-subventricular zone (V-SVZ) of the adult rodent brain generate several subtypes of interneurons that regulate the function of the olfactory bulb....
Age Factors Animals Cerebral Ventricles Gene Expression Regulation Developmental Glial Fibrillary Acidic Protein Green Fluorescent Proteins Homeodomain Proteins Interneurons Kruppel-Like Transcription Factors Membrane Microdomains Mice Neural Stem Cells Neuroglia RNA Untranslated Transcription Factors Transduction Genetic Zinc Finger Protein GLI1
Origins and Proliferative States of Human Oligodendrocyte Precursor Cells.
Wei Huang, Aparna Bhaduri, Dmitry Velmeshev, Shaohui Wang, Li Wang, Catherine A Rottkamp, Arturo Alvarez-Buylla, David H Rowitch, Arnold R Kriegstein
Aug 05, 2020
Human cerebral cortex size and complexity has increased greatly during evolution. While increased progenitor diversity and enhanced proliferative potential play important roles in human neurogenesis and gray matter expansion...
EGFR OPC PCDH15 cortical expansion oligodendrogenesis self-repulsion Cadherin Related Proteins Cadherins Cell Proliferation Cells Cultured Cerebral Cortex Ependymoglial Cells ErbB Receptors HEK293 Cells Humans Immunohistochemistry Neurogenesis oligodendrocyte precursor cells RNA Small Interfering RNA-seq Single-Cell Analysis white matter
Influence of mild-moderate hypocapnia on intracranial pressure slow waves activity in TBI.
Erta Beqiri, Marek Czosnyka, Afroditi D Lalou, Frederick A Zeiler, Marta Fedriga, Luzius A Steiner, Arturo Chieregato, Peter Smielewski
Nov 11, 2019
BACKGROUND: In traumatic brain injury (TBI) the patterns of intracranial pressure (ICP) waveforms may reflect pathological processes that ultimately lead to unfavorable outcome. In particular, ICP slow waves (sw) (0.005-0.05 Hz)...
MPK6 Kinase Regulates Plasma Membrane H<sup>+</sup>-ATPase Activity in Cold Acclimation.
Ilian Giordano Ponce-Pineda, Laura Carmona-Salazar, Mariana Saucedo-García, Dora Cano-Ramírez, Francisco Morales-Cedillo, Araceli Peña-Moral, Ángel Arturo Guevara-García, Sobeida Sánchez-Nieto, Marina Gavilanes-Ruíz
Aug 02, 2021
Cold and freezing stresses severely affect plant growth, development, and survival rate. Some plant species have evolved a process known as cold acclimation, in which plants exposed to temperatures above 0 °C trigger biochemical...
plasma membrane Cold acclimation MAPK freezing tolerance Mitogen Activated Protein Kinases H+-atpase Mpk3 Mpk6 Cell Membrane Arabidopsis Proton-Translocating ATPases Mitogen-Activated Protein Kinases Arabidopsis Proteins Acclimatization Protein Biosynthesis Transcription Genetic Membrane Fluidity Kinetics Freezing Cold Temperature
Published by: International journal of molecular sciences
MPK6 Kinase Regulates Plasma Membrane H + -ATPase Activity in Cold Acclimation
Ilian Giordano Ponce-Pineda, Laura Carmona-Salazar, Mariana Saucedo-García, Dora Cano-Ramírez, Francisco Morales-Cedillo, Araceli Peña-Moral, Ángel Arturo Guevara-García, Sobeida Sánchez-Nieto, Marina Gavilanes-Ruíz
Jun 14, 2021
Cold and freezing stresses severely affect plant growth, development, and survival rate. Some plant species have evolved a process known as cold acclimation, in which plants exposed to temperatures above 0 °C trigger biochemical...
MPK6 Kinase Regulates Plasma Membrane H+-ATPase Activity in Cold Acclimation.
Ilian Giordano Ponce-Pineda, Laura Carmona-Salazar, Mariana Saucedo-García, Dora Cano-Ramírez, Francisco Morales-Cedillo, Araceli Peña-Moral, Ángel Arturo Guevara-García, Sobeida Sánchez-Nieto, Marina Gavilanes-Ruíz
Sep 01, 2021
Cold and freezing stresses severely affect plant growth, development, and survival rate. Some plant species have evolved a process known as cold acclimation, in which plants exposed to temperatures above 0 °C trigger biochemical...
H+-atpase MAPK Mpk3 Mpk6 Cold acclimation freezing tolerance Mitogen Activated Protein Kinases plasma membrane Acclimatization Arabidopsis Arabidopsis Proteins Cell Membrane Cold Temperature Freezing Kinetics Membrane Fluidity Mitogen-Activated Protein Kinases Protein Biosynthesis Proton-Translocating ATPases Transcription Genetic
The influence of time on the sensitivity of SARS-CoV-2 serological testing.
Arturo Torres Ortiz, Fernanda Fenn Torrente, Adam Twigg, James Hatcher, Anja Saso, Tanya Lam, Marina Johnson, Helen Wagstaffe, Rishi Dhillon, Anabelle Lea Mai, David Goldblatt, Rachel Still, Matthew Buckland, Kimberly Gilmour, Louis Grandjean
Jun 29, 2022
Sensitive serological testing is essential to estimate the proportion of the population exposed or infected with SARS-CoV-2, to guide booster vaccination and to select patients for treatment with anti-SARS-CoV-2 antibodies. The...
Transcriptional silencing of long noncoding RNA GNG12-AS1 uncouples its transcriptional and product-related functions.
Lovorka Stojic, Malwina Niemczyk, Arturo Orjalo, Yoko Ito, Anna Elisabeth Maria Ruijter, Santiago Uribe-Lewis, Nimesh Joseph, Stephen Weston, Suraj Menon, Duncan T Odom, John Rinn, Fanni Gergely, Adele Murrell
Nov 24, 2015
The influence of time on the sensitivity of SARS-CoV-2 serological testing.
Arturo Torres Ortiz, Fernanda Fenn Torrente, Adam Twigg, James Hatcher, Anja Saso, Tanya Lam, Marina Johnson, Helen Wagstaffe, Rishi Dhillon, Anabelle Lea Mai, David Goldblatt, Rachel Still, Matthew Buckland, Kimberly Gilmour, Louis Grandjean
Jul 23, 2022
Sensitive serological testing is essential to estimate the proportion of the population exposed or infected with SARS-CoV-2, to guide booster vaccination and to select patients for treatment with anti-SARS-CoV-2 antibodies. The...
Genomic imprinting variations in the mouse type 3 deiodinase gene between tissues and brain regions.
M Elena Martinez, Marika Charalambous, Aabida Saferali, Steven Fiering, Anna K Naumova, Donald St Germain, Anne C Ferguson-Smith, Arturo Hernandez
Oct 02, 2014
In vivo visualization of age-related differences in the locus coeruleus.
Kathy Y Liu, Julio Acosta-Cabronero, Arturo Cardenas-Blanco, Clare Loane, Alex J Berry, Matthew J Betts, Rogier A Kievit, Richard N Henson, Emrah Düzel, Cam-CAN, Robert Howard, Dorothea Hämmerer
Dec 18, 2018
The locus coeruleus (LC), the major origin of noradrenergic modulation of the central nervous system, may play an important role in neuropsychiatric disorders including Parkinson's disease and Alzheimer's disease. The pattern of...
Influence of mild-moderate hypocapnia on intracranial pressure slow waves activity in TBI
Erta Beqiri, Marek Czosnyka, Afroditi D. Lalou, Frederick A. Zeiler, Marta Fedriga, Luzius A. Steiner, Arturo Chieregato, Peter Smielewski
Dec 22, 2020
The Bilayer Collective Properties Govern the Interaction of an HIV-1 Antibody with the Viral Membrane
Pablo Carravilla, Leonardo Darré, Itziar R Oar-Arteta, Arturo G Vesga, Edurne Rujas, Gloria de Las Heras-Martínez, Carmen Domene, Jose L Nieva, Jose Requejo-Isidro
Jan 07, 2020
Efficient engagement with the envelope glycoprotein membrane-proximal external region (MPER) results in robust blocking of viral infection by a class of broadly neutralizing antibodies (bnAbs) against human immunodeficiency...
Influence of mild-moderate hypocapnia on intracranial pressure slow waves activity in TBI
Erta Beqiri, Marek Czosnyka, Afroditi D. Lalou, Frederick A. Zeiler, Marta Fedriga, Luzius A. Steiner, Arturo Chieregato, Peter Smielewski
Jun 06, 2020
The Bilayer Collective Properties Govern the Interaction of an HIV-1 Antibody with the Viral Membrane
Pablo Carravilla, Leonardo Darré, Itziar R Oar-Arteta, Arturo G Vesga, Edurne Rujas, Gloria de Las Heras-Martínez, Carmen Domene, Jose L Nieva, Jose Requejo-Isidro
Jan 07, 2020
Efficient engagement with the envelope glycoprotein membrane-proximal external region (MPER) results in robust blocking of viral infection by a class of broadly neutralizing antibodies (bnAbs) against human immunodeficiency...
Extensive migration of young neurons into the infant human frontal lobe.
Mercedes F Paredes, David James, Sara Gil-Perotin, Hosung Kim, Jennifer A Cotter, Carissa Ng, Kadellyn Sandoval, David H Rowitch, Duan Xu, Patrick S McQuillen, Jose-Manuel Garcia-Verdugo, Eric J Huang, Arturo Alvarez-Buylla
Nov 21, 2017
The first few months after birth, when a child begins to interact with the environment, are critical to human brain development. The human frontal lobe is important for social behavior and executive function; it has increased in...
Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age
Amitava Banerjee, Laura Pasea, Steve Harris, Arturo Gonzalez-Izquierdo, Ana Torralbo, Laura Shallcross, Mahdad Noursadeghi, Deenan Pillay, Neil Sebire, Chris Holmes, Christina Pagel, Wai Keong Wong, Claudia Langenberg, Bryan Williams, Spiros Denaxas, Harry Hemingway
Jan 14, 2021
BACKGROUND: The medical, societal, and economic impact of the coronavirus disease 2019 (COVID-19) pandemic has unknown effects on overall population mortality. Previous models of population mortality are based on death over days...
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