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Results: 32
Short-term efficacy and safety of rituximab therapy in refractory systemic lupus erythematosus
Eoghan M McCarthy, Emily Sutton, Stephanie Nesbit, James White, Ben Parker, David Jayne, Bridget Griffiths, David A Isenberg, Anisur Rahman, Caroline Gordon, David P D'Cruz, Benjamin Rhodes, Peter Lanyon, Edward M Vital, Chee-Seng Yee, Christopher J Edwards, Lee-Suan Teh, Mohammed Akil, Neil J McHugh, Asad Zoma, Ian N Bruce, British Isles Lupus Assessment Group Biologics Register
Dec 11, 2019
OBJECTIVES: To describe the baseline characteristics of SLE patients requiring biologic therapy in the UK and to explore short term efficacy and infection rates associated with rituximab (RTX) use. METHODS: Patients commencing...
Biomarker Identification From Gene Expression Based on Symmetrical Uncertainty
In this paper, the authors present an effective information theoretic feature selection method, symmetrical uncertainty, to classify gene expression microarray data and detect biomarkers from it. Here, information gain and...
Published by: IGI Global Scientific Publishing
A Comparative Study on Therapeutic modalities in the Management of Spinal Anesthesia-Induced Hypotension in Parturient in Cesarean Delivery
Objective: was to compare the two therapeutic modalities, fluid preloading and ephedrine, in the management of spinal anesthesia-induced hypotension in patients undergoing elective cesarean delivery.
Methodology: Following...
Published by: IJHS Medical Association
Sensing and seeing associated with overlapping occipitoparietal activation in simultaneous EEG-fMRI.
The presence of a change in a visual scene can influence brain activity and behavior, even in the absence of full conscious report. It may be possible for us to sense that such a change has occurred, even if we cannot specify...
AI-Powered “Voice Recognition Avatar”
Consumers like to try innovative technologies when they perceive them to be approachable, convenient, and entertaining. The purpose of this study was to explore the adoption of AI voice recognition avatar in the gameplay. This...
Published by: IGI Global Scientific Publishing
A Comparative Study on Therapeutic modalities in the Management of Spinal Anesthesia-Induced Hypotension in Parturient in Cesarean Delivery
Objective: was to compare the two therapeutic modalities, fluid preloading and ephedrine, in the management of spinal anesthesia-induced hypotension in patients undergoing elective cesarean delivery.
Methodology: Following...
Published by: IJHS Medical Association
Sensing and seeing associated with overlapping occipitoparietal activation in simultaneous EEG-fMRI.
The presence of a change in a visual scene can influence brain activity and behavior, even in the absence of full conscious report. It may be possible for us to sense that such a change has occurred, even if we cannot...
Published by: Neuroscience of consciousness
Reversible Data Hiding with Multiple Data for Multiple Users in an Encrypted Image
This article presents a new method which embeds multiple data from multiple users in an encrypted image. Here, the data from several users is embedded into an encrypted image. Initially, the image is encrypted by the owner...
Published by: IGI Global Scientific Publishing
Psychosis in Systemic Lupus Erythematosus
John G Hanly, Qiuju Li, Li Su, Murray B Urowitz, Caroline Gordon, Sang-Cheol Bae, Juanita Romero-Diaz, Jorge Sanchez-Guerrero, Sasha Bernatsky, Ann E Clarke, Daniel J Wallace, David A Isenberg, Anisur Rahman, Joan T Merrill, Paul R Fortin, Dafna D Gladman, Ian N Bruce, Michelle Petri, Ellen M Ginzler, MA Dooley, Kristjan Steinsson, Rosalind Ramsey-Goldman, Asad A Zoma, Susan Manzi, Ola Nived, Andreas Jonsen, Munther A Khamashta, Graciela S Alarcón, Ronald F van Vollenhoven, Cynthia Aranow, Meggan Mackay, Guillermo Ruiz-Irastorza, Manuel Ramos-Casals, S Sam Lim, Murat Inanc, Kenneth C Kalunian, Soren Jacobsen, Christine A Peschken, Diane L Kamen, Anca Askanase, Chris Theriault, Vernon Farewell
Dec 12, 2018
OBJECTIVE: To determine, in a large, multiethnic/multiracial, prospective inception cohort of patients with systemic lupus erythematosus (SLE), the frequency, attribution, clinical, and autoantibody associations with lupus...
Adult Age Factors Antibodies Anticardiolipin Autoantibodies Cohort Studies Female Humans Kaplan-Meier Estimate Linear Models Lupus Coagulation Inhibitor Lupus Erythematosus Systemic Lupus Vasculitis Central Nervous System Male Middle Aged Proportional Hazards Models Prospective Studies Psychotic Disorders Receptors N-Methyl-D-Aspartate Sex Factors Young Adult beta 2-Glycoprotein I
Published by: Arthritis Rheumatol
Peripheral Nervous System Disease in Systemic Lupus Erythematosus
John G Hanly, Qiuju Li, Li Su, Murray B Urowitz, Caroline Gordon, Sang-Cheol Bae, Juanita Romero-Diaz, Jorge Sanchez-Guerrero, Sasha Bernatsky, Ann E Clarke, Daniel J Wallace, David A Isenberg, Anisur Rahman, Joan T Merrill, Paul R Fortin, Dafna D Gladman, Ian N Bruce, Michelle Petri, Ellen M Ginzler, MA Dooley, Kristjan Steinsson, Rosalind Ramsey-Goldman, Asad A Zoma, Susan Manzi, Ola Nived, Andreas Jonsen, Munther A Khamashta, Graciela S Alarcón, Elisabet Svenungsson, Ronald F van Vollenhoven, Cynthia Aranow, Meggan Mackay, Guillermo Ruiz-Irastorza, Manuel Ramos-Casals, S Sam Lim, Murat Inanc, Kenneth C Kalunian, Soren Jacobsen, Christine A Peschken, Diane L Kamen, Anca Askanase, Chris Theriault, Vernon Farewell
Aug 19, 2019
OBJECTIVE: To determine the frequency, clinical characteristics, associations, and outcomes of different types of peripheral nervous system (PNS) disease in a multiethnic/multiracial, prospective inception cohort of systemic...
Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern
Katherine A Twohig, Tommy Nyberg, Asad Zaidi, Simon Thelwall, Mary A Sinnathamby, Shirin Aliabadi, Shaun R Seaman, Ross J Harris, Russell Hope, Jamie Lopez-Bernal, Eileen Gallagher, Andre Charlett, Daniela De Angelis, Anne M Presanis, Gavin Dabrera
Oct 01, 2021
Published by: The Lancet. Infectious diseases
Mood Disorders in Systemic Lupus Erythematosus
John G Hanly, Li Su, Murray B Urowitz, Juanita Romero-Diaz, Caroline Gordon, Sang-Cheol Bae, Sasha Bernatsky, Ann E Clarke, Daniel J Wallace, Joan T Merrill, David A Isenberg, Anisur Rahman, Ellen M Ginzler, Michelle Petri, Ian N Bruce, MA Dooley, Paul Fortin, Dafna D Gladman, Jorge Sanchez-Guerrero, Kristjan Steinsson, Rosalind Ramsey-Goldman, Munther A Khamashta, Cynthia Aranow, Graciela S Alarcón, Barri J Fessler, Susan Manzi, Ola Nived, Gunnar K Sturfelt, Asad A Zoma, Ronald F van Vollenhoven, Manuel Ramos-Casals, Guillermo Ruiz-Irastorza, S Sam Lim, Kenneth C Kalunian, Murat Inanc, Diane L Kamen, Christine A Peschken, Soren Jacobsen, Anca Askanase, Chris Theriault, Kara Thompson, Vernon Farewell
Jun 12, 2018
OBJECTIVE: To examine the frequency, characteristics, and outcome of mood disorders, as well as clinical and autoantibody associations, in a multiethnic/racial, prospective inception cohort of patients with systemic lupus...
Humans Lupus Erythematosus Systemic Disease Progression Autoantibodies Incidence Regression Analysis Cohort Studies Prospective Studies Mood Disorders Internationality Quality of life Adult Middle Aged African Continental Ancestry Group Asian Continental Ancestry Group European Continental Ancestry Group Hispanic Americans Female Male
Factors associated with damage accrual in patients with systemic lupus erythematosus
Ian N Bruce, Aidan G O'Keeffe, Vern Farewell, John G Hanly, Susan Manzi, Li Su, Dafna D Gladman, Sang-Cheol Bae, Jorge Sanchez-Guerrero, Juanita Romero-Diaz, Caroline Gordon, Daniel J Wallace, Ann E Clarke, Sasha Bernatsky, Ellen M Ginzler, David A Isenberg, Anisur Rahman, Joan T Merrill, Graciela S Alarcón, Barri J Fessler, Paul R Fortin, Michelle Petri, Kristjan Steinsson, Mary Anne Dooley, Munther A Khamashta, Rosalind Ramsey-Goldman, Asad A Zoma, Gunnar K Sturfelt, Ola Nived, Cynthia Aranow, Meggan Mackay, Manuel Ramos-Casals, Ronald F van Vollenhoven, Kenneth C Kalunian, Guillermo Ruiz-Irastorza, Sam Lim, Diane L Kamen, Christine A Peschken, Murat Inanc, Murray B Urowitz
Jun 12, 2018
BACKGROUND AND AIMS: We studied damage accrual and factors determining development and progression of damage in an international cohort of systemic lupus erythematosus (SLE) patients. METHODS: The Systemic Lupus International...
corticosteroids Inflammation outcomes research Systemic Lupus Erythematosus Adult Cohort Studies Disease Progression Ethnicity Female health status Humans Kaplan-Meier Estimate Longitudinal Studies Lupus Erythematosus Systemic Male Middle Aged Proportional Hazards Models Prospective Studies Quality of life Young Adult
Accrual of Atherosclerotic Vascular Events in a Multicenter Inception Systemic Lupus Erythematosus Cohort.
Murray B Urowitz, Dafna D Gladman, Vernon Farewell, Jiandong Su, Juanita Romero-Diaz, Sang-Cheol Bae, Paul R Fortin, Jorge Sanchez-Guerrero, Ann Elaine Clarke, Sasha Bernatsky, Caroline Gordon, John G Hanly, Daniel J Wallace, David A Isenberg, Anisur Rahman, Joan T Merrill, Ellen Ginzler, Graciela S Alarcón, W Winn Chatham, Michelle A Petri, Ian N Bruce, Munther A Khamashta, Cynthia Aranow, Mary Anne Dooley, Susan Manzi, Rosalind Ramsey-Goldman, Ola Nived, Andreas Jönsen, Kristján Steinsson, Asad A Zoma, Guillermo Ruiz-Irastorza, S Sam Lim, Kenneth C Kalunian, Murat Ỉnanç, Ronald Van Vollenhoven, Manuel Ramos-Casals, Diane L Kamen, Soren Jacobsen, Christine A Peschken, Anca Askanase, Thomas Stoll
Sep 14, 2020
OBJECTIVE: In previous studies, atherosclerotic vascular events (AVEs) were shown to occur in ~10% of patients with systemic lupus erythematosus (SLE). We undertook this study to investigate the annual occurrence and potential...
Prevalence of Multiplicity and Appropriate Adjustments Among Cardiovascular Randomized Clinical Trials Published in Major Medical Journals.
Muhammad Shahzeb Khan, Maaz Shah Khan, Zunaira Navid Ansari, Tariq Jamal Siddiqi, Safi U Khan, Irbaz Bin Riaz, Zain Ul Abideen Asad, John Mandrola, James Wason, Haider J Warraich, Gregg W Stone, Deepak L Bhatt, Samir R Kapadia, Ankur Kalra
May 11, 2020
IMPORTANCE: Multiple analyses in a clinical trial can increase the probability of inaccurately concluding that there is a statistically significant treatment effect. However, to date, it is unknown how many randomized clinical...
Optimizing Sustainable Performance Green Talent Management Strategies Focused on Core Competencies
This study aims to examine the relationship among green innovation performance (GIP), sustainable performance (SP), and green talent management (GTM) through the lens of natural resource. It investigates the moderating impact of...
Published by: IGI Global Scientific Publishing
Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern
Katherine A Twohig, Tommy Nyberg, Asad Zaidi, Simon Thelwall, Mary A Sinnathamby, Shirin Aliabadi, Shaun R Seaman, Ross J Harris, Russell Hope, Jamie Lopez-Bernal, Eileen Gallagher, Andre Charlett, Daniela De Angelis, Anne M Presanis, Gavin Dabrera, COVID-19 Genomics UK (COG-UK) Consortium
Oct 06, 2021
Plasma Metabolomic Changes following PI3K Inhibition as Pharmacodynamic Biomarkers
Joo Ern Ang, Rupinder Pandher, Joo Chew Ang, Yasmin J Asad, Alan T Henley, Melanie Valenti, Gary Box, Alexis de Haven Brandon, Richard D Baird, Lori Friedman, Mika Derynck, Bart Vanhaesebroeck, Suzanne A Eccles, Stan B Kaye, Paul Workman, Johann S de Bono, Florence I Raynaud
May 27, 2016
Hospitalization and Mortality Risk for COVID-19 Cases With SARS-CoV-2 AY.4.2 (VUI-21OCT-01) Compared to Non-AY.4.2 Delta Variant Sublineages.
Tommy Nyberg, Katie Harman, Asad Zaidi, Shaun R Seaman, Nick Andrews, Sophie G Nash, Andre Charlett, Jamie Lopez Bernal, Richard Myers, Natalie Groves, Eileen Gallagher, Saheer Gharbia, Meera Chand, Simon Thelwall, Daniela De Angelis, Gavin Dabrera, Anne M Presanis
Mar 28, 2022
A Longitudinal Analysis of Outcomes of Lupus Nephritis in an International Inception Cohort Using a Multistate Model Approach.
John G Hanly, Li Su, Murray B Urowitz, Juanita Romero-Diaz, Caroline Gordon, Sang-Cheol Bae, Sasha Bernatsky, Ann E Clarke, Daniel J Wallace, Joan T Merrill, David A Isenberg, Anisur Rahman, Ellen M Ginzler, Michelle Petri, Ian N Bruce, MA Dooley, Paul Fortin, Dafna D Gladman, Jorge Sanchez-Guerrero, Kristjan Steinsson, Rosalind Ramsey-Goldman, Munther A Khamashta, Cynthia Aranow, Graciela S Alarcón, Barri J Fessler, Susan Manzi, Ola Nived, Gunnar K Sturfelt, Asad A Zoma, Ronald F van Vollenhoven, Manuel Ramos-Casals, Guillermo Ruiz-Irastorza, S Sam Lim, Kenneth C Kalunian, Murat Inanc, Diane L Kamen, Christine A Peschken, Soren Jacobsen, Anca Askanase, Chris Theriault, Vernon Farewell
Jun 11, 2018
OBJECTIVE: To study bidirectional change and predictors of change in estimated glomerular filtration rate (GFR) and proteinuria in lupus nephritis (LN) using a multistate modeling approach. METHODS: Patients in the Systemic...
Cerebrovascular Events in Systemic Lupus Erythematosus
John G Hanly, Qiuju Li, Li Su, Murray B Urowitz, Caroline Gordon, Sang-Cheol Bae, Juanita Romero-Diaz, Jorge Sanchez-Guerrero, Sasha Bernatsky, Ann E Clarke, Daniel J Wallace, David A Isenberg, Anisur Rahman, Joan T Merrill, Paul Fortin, Dafna D Gladman, Ian N Bruce, Michelle Petri, Ellen M Ginzler, MA Dooley, Kristjan Steinsson, Rosalind Ramsey-Goldman, Asad A Zoma, Susan Manzi, Ola Nived, Andreas Jonsen, Munther A Khamashta, Graciela S Alarcón, Winn Chatham, Ronald F van Vollenhoven, Cynthia Aranow, Meggan Mackay, Guillermo Ruiz-Irastorza, Manuel Ramos-Casals, S Sam Lim, Murat Inanc, Kenneth C Kalunian, Soren Jacobsen, Christine A Peschken, Diane L Kamen, Anca Askanase, Chris Theriault, Vernon Farewell
Jun 11, 2018
OBJECTIVE: To determine the frequency, characteristics, and outcomes of cerebrovascular events (CerVEs), as well as clinical and autoantibody associations in a multiethnic/racial inception cohort of patients with systemic lupus...
Economic Evaluation of Lupus Nephritis in the Systemic Lupus International Collaborating Clinics Inception Cohort Using a Multistate Model Approach.
Megan RW Barber, John G Hanly, Li Su, Murray B Urowitz, Yvan St Pierre, Juanita Romero-Diaz, Caroline Gordon, Sang-Cheol Bae, Sasha Bernatsky, Daniel J Wallace, David A Isenberg, Anisur Rahman, Ellen M Ginzler, Michelle Petri, Ian N Bruce, Paul R Fortin, Dafna D Gladman, Jorge Sanchez-Guerrero, Rosalind Ramsey-Goldman, Munther A Khamashta, Cynthia Aranow, Meggan Mackay, Graciela S Alarcón, Susan Manzi, Ola Nived, Andreas Jönsen, Asad A Zoma, Ronald F van Vollenhoven, Manuel Ramos-Casals, Guillermo Ruiz-Irastorza, S Sam Lim, Kenneth C Kalunian, Murat Inanc, Diane L Kamen, Christine A Peschken, Soren Jacobsen, Anca Askanase, Chris Theriault, Vernon Farewell, Ann E Clarke
Jun 11, 2018
OBJECTIVE: Little is known about the long-term costs of lupus nephritis (LN). The costs were compared between patients with and without LN using multistate modeling. METHODS: Patients from 32 centers in 11 countries were...
The frequency and outcome of lupus nephritis
John G Hanly, Aidan G O'Keeffe, Li Su, Murray B Urowitz, Juanita Romero-Diaz, Caroline Gordon, Sang-Cheol Bae, Sasha Bernatsky, Ann E Clarke, Daniel J Wallace, Joan T Merrill, David A Isenberg, Anisur Rahman, Ellen M Ginzler, Paul Fortin, Dafna D Gladman, Jorge Sanchez-Guerrero, Michelle Petri, Ian N Bruce, Mary Anne Dooley, Rosalind Ramsey-Goldman, Cynthia Aranow, Graciela S Alarcón, Barri J Fessler, Kristjan Steinsson, Ola Nived, Gunnar K Sturfelt, Susan Manzi, Munther A Khamashta, Ronald F van Vollenhoven, Asad A Zoma, Manuel Ramos-Casals, Guillermo Ruiz-Irastorza, S Sam Lim, Thomas Stoll, Murat Inanc, Kenneth C Kalunian, Diane L Kamen, Peter Maddison, Christine A Peschken, Soren Jacobsen, Anca Askanase, Chris Theriault, Kara Thompson, Vernon Farewell
Jun 12, 2018
OBJECTIVE: To determine nephritis outcomes in a prospective multi-ethnic/racial SLE inception cohort. METHODS: Patients in the Systemic Lupus International Collaborating Clinics inception cohort (≤15 months of SLE diagnosis)...
inception cohort lupus nephritis outcomes research Systemic Lupus Erythematosus Adult Disease Progression Ethnicity Female Follow-Up Studies Global Health Humans Incidence Lupus Nephritis Male Outcome Assessment Health Care Prospective Studies Quality of life Risk Factors Surveys and Questionnaires Survival Rate
Economic Evaluation of Damage Accrual in an International Systemic Lupus Erythematosus Inception Cohort Using a Multistate Model Approach.
Megan RW Barber, John G Hanly, Li Su, Murray B Urowitz, Yvan St Pierre, Juanita Romero-Diaz, Caroline Gordon, Sang-Cheol Bae, Sasha Bernatsky, Daniel J Wallace, Joan T Merrill, David A Isenberg, Anisur Rahman, Ellen M Ginzler, Michelle Petri, Ian N Bruce, Mary A Dooley, Paul R Fortin, Dafna D Gladman, Jorge Sanchez-Guerrero, Kristjan Steinsson, Rosalind Ramsey-Goldman, Munther A Khamashta, Cynthia Aranow, Meggan Mackay, Graciela S Alarcón, Susan Manzi, Ola Nived, Andreas Jönsen, Asad A Zoma, Ronald F van Vollenhoven, Manuel Ramos-Casals, Guillermo Ruiz-Irastorza, S Sam Lim, Kenneth C Kalunian, Murat Inanc, Diane L Kamen, Christine A Peschken, Søren Jacobsen, Anca Askanase, Vernon Farewell, Thomas Stoll, Jill Buyon, Ann E Clarke
Oct 01, 2019
OBJECTIVE: There is a paucity of data regarding health care costs associated with damage accrual in systemic lupus erythematosus. The present study was undertaken to describe costs associated with damage states across the...
Comparative analysis of the risks of hospitalisation and death associated with SARS-CoV-2 omicron (B.1.1.529) and delta (B.1.617.2) variants in England
Tommy Nyberg, Neil M Ferguson, Sophie G Nash, Harriet H Webster, Seth Flaxman, Nick Andrews, Wes Hinsley, Jamie Lopez Bernal, Meaghan Kall, Samir Bhatt, Paula Blomquist, Asad Zaidi, Erik Volz, Nurin Abdul Aziz, Katie Harman, Sebastian Funk, Sam Abbott, COVID-19 Genomics UK (COG-UK) Consortium, Russell Hope, Andre Charlett, Meera Chand, Azra C Ghani, Shaun R Seaman, Gavin Dabrera, Daniela De Angelis, Anne M Presanis, Simon Thelwall
Apr 19, 2022
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