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Results: 47
In Vivo Predictive Dissolution and Simulation Workshop Report
Yasuhiro Tsume, Sanjaykumar Patel, Nikoletta Fotaki, Christel Bergstrӧm, Gordon L. Amidon, James G. Brasseur, Deanna M. Mudie, Duxin Sun, Marival Bermejo, Ping Gao, Wei Zhu, David C. Sperry, Maria Vertzoni, Neil Parrott, Robert Lionberger, Atsushi Kambayashi, Andre Hermans, Xujin Lu, Gregory E. Amidon
Nov 01, 2018
In Vivo Predictive Dissolution and Simulation Workshop Report
Yasuhiro Tsume, Sanjaykumar Patel, Nikoletta Fotaki, Christel Bergstrӧm, Gordon L. Amidon, James G. Brasseur, Deanna M. Mudie, Duxin Sun, Marival Bermejo, Ping Gao, Wei Zhu, David C. Sperry, Maria Vertzoni, Neil Parrott, Robert Lionberger, Atsushi Kambayashi, Andre Hermans, Xujin Lu, Gregory E. Amidon
Nov 01, 2018
Infant neural sensitivity to eye gaze depends on early experience of gaze communication.
Angélina Vernetti, Nataşa Ganea, Leslie Tucker, Tony Charman, Mark H Johnson, Atsushi Senju
Sep 05, 2018
A fundamental question in functional brain development is how the brain acquires specialised processing optimised for its individual environment. The current study is the first to demonstrate that distinct experience of eye gaze...
Thermal physics of the lead chalcogenides PbS, PbSe, and PbTe from first principles
The lead chalcogenides represent an important family of functional materials, in particular due to the benchmark high-temperature thermoelectric performance of PbTe. A number of recent investigations, experimental and...
Measurement of caveolin-1 densities in the cell membrane for quantification of caveolar deformation after exposure to hypotonic membrane tension.
Masashi Tachikawa, Nobuhiro Morone, Yosuke Senju, Tadao Sugiura, Kyoko Hanawa-Suetsugu, Atsushi Mochizuki, Shiro Suetsugu
May 24, 2019
Caveolae are abundant flask-shaped invaginations of plasma membranes that buffer membrane tension through their deformation. Few quantitative studies on the deformation of caveolae have been reported. Each caveola contains...
Influence of the exchange-correlation functional on the quasi-harmonic lattice dynamics of II-VI semiconductors
Jonathan M. Skelton, Davide Tiana, Stephen C. Parker, Atsushi Togo, Isao Tanaka, Aron Walsh
Aug 14, 2015
We perform a systematic comparison of the finite-temperature structure and properties of four bulk semiconductors (PbS, PbTe, ZnS, and ZnTe) predicted by eight popular exchange-correlation functionals from quasi-harmonic...
Thermal physics of the lead chalcogenides PbS, PbSe, and PbTe from first principles
The lead chalcogenides represent an important family of functional materials, in particular due to the benchmark high-temperature thermoelectric performance of PbTe. A number of recent investigations, experimental and...
Simulating interaction
Angelina Vernetti, Atsushi Senju, Tony Charman, Mark H Johnson, Teodora Gliga, BASIS Team
May 09, 2019
Several accounts have been proposed to explain difficulties with social interaction in autism spectrum disorder (ASD), amongst which atypical social orienting, decreased social motivation or difficulties with understanding the...
Development of adaptive communication skills in infants of blind parents.
Nataşa Ganea, Kristelle Hudry, Angélina Vernetti, Leslie Tucker, Tony Charman, Mark H Johnson, Atsushi Senju
Sep 08, 2018
Suppression of lattice thermal conductivity by mass-conserving cation mutation in multi-component semiconductors
Taizo Shibuya, Jonathan M. Skelton, Adam J. Jackson, Kenji Yasuoka, Atsushi Togo, Isao Tanaka, Aron Walsh
Oct 01, 2016
In semiconductors almost all heat is conducted by phonons (lattice vibrations), which is limited by their quasi-particle lifetimes. Phonon-phonon interactions represent scattering mechanisms that produce thermal resistance. In...
Suppression of lattice thermal conductivity by mass-conserving cation mutation in multi-component semiconductors
Taizo Shibuya, Jonathan M. Skelton, Adam J. Jackson, Kenji Yasuoka, Atsushi Togo, Isao Tanaka, Aron Walsh
Oct 01, 2016
In semiconductors almost all heat is conducted by phonons (lattice vibrations), which is limited by their quasi-particle lifetimes. Phonon-phonon interactions represent scattering mechanisms that produce thermal resistance. In...
Influence of the exchange-correlation functional on the quasi-harmonic lattice dynamics of II-VI semiconductors
Jonathan M. Skelton, Davide Tiana, Stephen C. Parker, Atsushi Togo, Isao Tanaka, Aron Walsh
Aug 14, 2015
We perform a systematic comparison of the finite-temperature structure and properties of four bulk semiconductors (PbS, PbTe, ZnS, and ZnTe) predicted by eight popular exchange-correlation functionals from quasi-harmonic...
Ancient Jomon genome sequence analysis sheds light on migration patterns of early East Asian populations
Takashi Gakuhari, Shigeki Nakagome, Simon Rasmussen, Morten E. Allentoft, Takehiro Sato, Thorfinn Korneliussen, Blánaid Ní Chuinneagáin, Hiromi Matsumae, Kae Koganebuchi, Ryan Schmidt, Souichiro Mizushima, Osamu Kondo, Nobuo Shigehara, Minoru Yoneda, Ryosuke Kimura, Hajime Ishida, Tadayuki Masuyama, Yasuhiro Yamada, Atsushi Tajima, Hiroki Shibata, Atsushi Toyoda, Toshiyuki Tsurumoto, Tetsuaki Wakebe, Hiromi Shitara, Tsunehiko Hanihara, Eske Willerslev, Martin Sikora, Hiroki Oota
Aug 26, 2021
Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice.
Hiromi Yamazaki, Shuya Kasai, Junsei Mimura, Peng Ye, Atsushi Inose-Maruyama, Kunikazu Tanji, Koichi Wakabayashi, Seiya Mizuno, Fumihiro Sugiyama, Satoru Takahashi, Tsubasa Sato, Taku Ozaki, Douglas R Cavener, Masayuki Yamamoto, Ken Itoh
Apr 23, 2020
Amino acids exert many biological functions, serving as allosteric regulators and neurotransmitters, as constituents in proteins and as nutrients. GCN2-mediated phosphorylation of eukaryotic initiation factor 2 alpha (elF2α)...
Ancient Jomon genome sequence analysis sheds light on migration patterns of early East Asian populations
Takashi Gakuhari, Shigeki Nakagome, Simon Rasmussen, Morten E. Allentoft, Takehiro Sato, Thorfinn Korneliussen, Blánaid Ní Chuinneagáin, Hiromi Matsumae, Kae Koganebuchi, Ryan Schmidt, Souichiro Mizushima, Osamu Kondo, Nobuo Shigehara, Minoru Yoneda, Ryosuke Kimura, Hajime Ishida, Tadayuki Masuyama, Yasuhiro Yamada, Atsushi Tajima, Hiroki Shibata, Atsushi Toyoda, Toshiyuki Tsurumoto, Tetsuaki Wakebe, Hiromi Shitara, Tsunehiko Hanihara, Eske Willerslev, Martin Sikora, Hiroki Oota
Aug 25, 2020
Anharmonicity in the High-Temperature Cmcm Phase of SnSe
Jonathan Skelton, Lee Burton, Stephen Parker, Aron Walsh, Chang-eun Kim, Aloysius Soon, John Buckeridge, Alexey A. Sokol, C. Richard A. Catlow, Atsushi Togo, Isao Tanaka
Aug 12, 2016
The layered semiconductor SnSe is one of the highest-performing thermoelectric materials known. We demonstrate, through a first-principles lattice-dynamics study, that the high-temperature Cmcm phase is a dynamic average over...
Masato Miyake, Akitoshi Nomura, Atsushi Ogura, Kenji Takehana, Yoshihiro Kitahara, Kazuna Takahara, Kazue Tsugawa, Chinobu Miyamoto, Naoko Miura, Ryosuke Sato, Kiyoe Kurahashi, Heather P Harding, Miho Oyadomari, David Ron, Seiichi Oyadomari
Apr 28, 2016
Anharmonicity in the High-Temperature Cmcm Phase of SnSe
Jonathan Skelton, Lee Burton, Stephen Parker, Aron Walsh, Chang-eun Kim, Aloysius Soon, John Buckeridge, Alexey A. Sokol, C. Richard A. Catlow, Atsushi Togo, Isao Tanaka
Aug 12, 2016
The layered semiconductor SnSe is one of the highest-performing thermoelectric materials known. We demonstrate, through a first-principles lattice-dynamics study, that the high-temperature Cmcm phase is a dynamic average over...
The mouse C9ORF72 ortholog is enriched in neurons known to degenerate in ALS and FTD.
Naoki Suzuki, Asif M Maroof, Florian T Merkle, Kathryn Koszka, Atsushi Intoh, Ian Armstrong, Rob Moccia, Brandi N Davis-Dusenbery, Kevin Eggan
Oct 12, 2020
Using transgenic mice harboring a targeted LacZ insertion, we studied the expression pattern of the C9ORF72 mouse ortholog (3110043O21Rik). Unlike most genes that are mutated in amyotrophic lateral sclerosis (ALS), which are...
Acetylcholinesterase Aged Amyotrophic Lateral Sclerosis Animals Animals Newborn Brain C9orf72 Protein Cells Cultured Embryo Mammalian frontotemporal dementia Gene Expression Regulation Genotype Guanine Nucleotide Exchange Factors Homeodomain Proteins Humans Male Mice Mice Transgenic Mutation Nerve Tissue Proteins Neurons Nuclear Proteins Proteins Repressor Proteins Transcription Factors Transfection
The Subaru HSC Galaxy Clustering with Photometric Redshift. I. Dark Halo Masses versus Baryonic Properties of Galaxies at 0.3≤z≤ 1.4
Shogo Ishikawa, Nobunari Kashikawa, Masayuki Tanaka, Jean Coupon, Alexie Leauthaud, Jun Toshikawa, Kohei Ichikawa, Taira Oogi, Hisakazu Uchiyama, Yuu Niino, Atsushi J. Nishizawa
Nov 26, 2020
We present the clustering properties of low-z (z ≤ 1.4) galaxies selected by the Hyper Suprime-Cam Subaru Strategic Program Wide layer over 145 deg2. The wide-field and multiwavelength observation yields 5,064,770 galaxies at...
Energetics of lipid transport by the ABC transporter MsbA is lipid dependent.
Dawei Guo, Himansha Singh, Atsushi Shimoyama, Charlotte Guffick, Yakun Tang, Sam M Rowe, Timothy Noel, David R Spring, Koichi Fukase, Hendrik W van Veen
Jan 04, 2022
Ancient Jomon genome sequence analysis sheds light on migration patterns of early East Asian populations.
Takashi Gakuhari, Shigeki Nakagome, Simon Rasmussen, Morten E Allentoft, Takehiro Sato, Thorfinn Korneliussen, Blánaid Ní Chuinneagáin, Hiromi Matsumae, Kae Koganebuchi, Ryan Schmidt, Souichiro Mizushima, Osamu Kondo, Nobuo Shigehara, Minoru Yoneda, Ryosuke Kimura, Hajime Ishida, Tadayuki Masuyama, Yasuhiro Yamada, Atsushi Tajima, Hiroki Shibata, Atsushi Toyoda, Toshiyuki Tsurumoto, Tetsuaki Wakebe, Hiromi Shitara, Tsunehiko Hanihara, Eske Willerslev, Martin Sikora, Hiroki Oota
Oct 12, 2020
Anatomically modern humans reached East Asia more than 40,000 years ago. However, key questions still remain unanswered with regard to the route(s) and the number of wave(s) in the dispersal into East Eurasia. Ancient genomes at...
The Subaru HSC Galaxy Clustering with Photometric Redshift. I. Dark Halo Masses versus Baryonic Properties of Galaxies at 0.3≤z≤ 1.4
Shogo Ishikawa, Nobunari Kashikawa, Masayuki Tanaka, Jean Coupon, Alexie Leauthaud, Jun Toshikawa, Kohei Ichikawa, Taira Oogi, Hisakazu Uchiyama, Yuu Niino, Atsushi J. Nishizawa
Nov 26, 2020
We present the clustering properties of low-z (z ≤ 1.4) galaxies selected by the Hyper Suprime-Cam Subaru Strategic Program Wide layer over 145 deg2. The wide-field and multiwavelength observation yields 5,064,770 galaxies at...
Regulation of cargo-selective endocytosis by dynamin 2 GTPase-activating protein girdin.
Liang Weng, Atsushi Enomoto, Hiroshi Miyoshi, Kiyofumi Takahashi, Naoya Asai, Nobuhiro Morone, Ping Jiang, Jian An, Takuya Kato, Keisuke Kuroda, Takashi Watanabe, Masato Asai, Maki Ishida-Takagishi, Yoshiki Murakumo, Hideki Nakashima, Kozo Kaibuchi, Masahide Takahashi
May 28, 2019
In clathrin-mediated endocytosis (CME), specificity and selectivity for cargoes are thought to be tightly regulated by cargo-specific adaptors for distinct cellular functions. Here, we show that the actin-binding protein girdin...
Comparison of the Pharmacokinetics of RIPK1 Inhibitor GSK2982772 in Healthy Western and Japanese Subjects.
Debra J Tompson, Carwyn Davies, Nicola E Scott, Edward P Cannons, Michalis Kostapanos, Annette S Gross, Marcy Powell, Hiroko Ino, Ryutaro Shimamura, Hirofumi Ogura, Takashi Nagakubo, Harue Igarashi, Atsushi Nakano
Jan 18, 2021
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