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Results: 78791
Dietary stearic acid regulates mitochondria in vivo in humans.
Deniz Senyilmaz-Tiebe, Daniel H Pfaff, Sam Virtue, Kathrin V Schwarz, Thomas Fleming, Sandro Altamura, Martina U Muckenthaler, Jürgen G Okun, Antonio Vidal-Puig, Peter Nawroth, Aurelio A Teleman
Mar 28, 2019
Since modern foods are unnaturally enriched in single metabolites, it is important to understand which metabolites are sensed by the human body and which are not. We previously showed that the fatty acid stearic acid (C18:0)...
High-flow nasal oxygen vs. standard oxygen therapy for patients undergoing transcatheter aortic valve replacement with conscious sedation
S Scheuermann, A Tan, P Govender, M Mckie, J Pack, G Martinez, F Falter, S George, A A. Klein
Apr 14, 2023
A cryptic targeting signal creates a mitochondrial FEN1 isoform with tailed R-Loop binding properties.
Lawrence Kazak, Aurelio Reyes, Jiuya He, Stuart R Wood, Gloria Brea-Calvo, Torgeir T Holen, Ian J Holt
Nov 23, 2017
A growing number of DNA transacting proteins is found in the nucleus and in mitochondria, including the DNA repair and replication protein Flap endonuclease 1, FEN1. Here we show a truncated FEN1 isoform is generated by...
Fabrication of a 3D Nanomagnetic Circuit with Multi-Layered Materials for Applications in Spintronics.
Fanfan Meng, Claire Donnelly, Luka Skoric, Aurelio Hierro-Rodriguez, Jung-Wei Liao, Amalio Fernández-Pacheco
Oct 04, 2021
Three-dimensional (3D) spintronic devices are attracting significant research interest due to their potential for both fundamental studies and computing applications. However, their implementations face great challenges...
RNase H1 Regulates Mitochondrial Transcription and Translation via the Degradation of 7S RNA
RNase H1 is able to recognize DNA/RNA heteroduplexes and to degrade their RNA component. As a consequence, it has been implicated in different aspects of mtDNA replication such as primer formation, primer removal, and...
Achieving robustness to aleatoric uncertainty with heteroscedastic Bayesian optimisation
Ryan-Rhys Griffiths, Alexander A Aldrick, Miguel Garcia-Ortegon, Vidhi Lalchand, Alpha A Lee
Nov 23, 2021
Abstract: Bayesian optimisation is a sample-efficient search methodology that holds great promise for accelerating drug and materials discovery programs. A frequently-overlooked modelling consideration in Bayesian optimisation...
Environmentally-framed eWOM messages of different valence
Consumers are increasingly interested to know about the environmental impact of products and, at the same time, they form attitudes after reading online consumer reviews (OCRs). Researchers have investigated the influence of...
Environmentally-framed eWOM messages of different valence
Consumers are increasingly interested to know about the environmental impact of products and, at the same time, they form attitudes after reading online consumer reviews (OCRs). Researchers have investigated the influence of...
The Role of DNA Repair in Maintaining Mitochondrial DNA Stability.
Mitochondria are vital double-membrane organelles that act as a "powerhouse" inside the cell and have essential roles to maintain cellular functions, e.g., ATP production, iron-sulfur synthesis metabolism, and steroid synthesis....
A Model of Cloud Forensic Application With Assurance of Cloud Log
The key concepts of digital forensic investigation in cloud computing are examination and investigation. Cybercriminals target cloud-based web applications due to presence of vulnerabilities. Forensic investigation is a complex...
Published by: IGI Global Scientific Publishing
Fabrication of a 3D Nanomagnetic Circuit with Multi-Layered Materials for Applications in Spintronics
Fanfan Meng, Claire Donnelly, Luka Skoric, Aurelio Hierro-Rodriguez, Jung-Wei Liao, Amalio Fernández-Pacheco
Jul 28, 2021
Three-dimensional (3D) spintronic devices are attracting significant research interest due to their potential for both fundamental studies and computing applications. However, their implementations face great challenges...
Depression amongst interns working in a tertiary care teaching Hospital in Maharashtra
Background: Internship is a crucial stage of medical school regarding student stress which can affect thepatient care negatively. Retrieving knowledge about presence of depression is therefore important in itself and iffound...
Published by: IJHS Medical Association
Depression amongst interns working in a tertiary care teaching Hospital in Maharashtra
Background: Internship is a crucial stage of medical school regarding student stress which can affect the patient care negatively. Retrieving knowledge about presence of depression is therefore important in itself and if found...
Published by: IJHS Medical Association
Phylogenetic analyses of complete mitochondrial genome sequences suggest a basal divergence of the enigmatic rodent Anomalurus.
David S Horner, Konstantinos Lefkimmiatis, Aurelio Reyes, Carmela Gissi, Cecilia Saccone, Graziano Pesole
Nov 23, 2017
BACKGROUND: Phylogenetic relationships between Lagomorpha, Rodentia and Primates and their allies (Euarchontoglires) have long been debated. While it is now generally agreed that Rodentia constitutes a monophyletic sister-group...
Mitochondrial DNA replication proceeds via a 'bootlace' mechanism involving the incorporation of processed transcripts.
Aurelio Reyes, Lawrence Kazak, Stuart R Wood, Takehiro Yasukawa, Howard T Jacobs, Ian J Holt
Nov 23, 2017
The observation that long tracts of RNA are associated with replicating molecules of mitochondrial DNA (mtDNA) suggests that the mitochondrial genome of mammals is copied by an unorthodox mechanism. Here we show that these...
Knowledge and Attitude among High School Students towards HIV / AIDS in Rural areas of Belagavi–A Cross Sectional Study
Asha A. Bellad and Rajesh R Kulkarni
Mar 25, 2015
Introduction Since its emergence in 1981, the HIV/AIDS pandemic, which poses a serious challenge to mankind, without doubt, has become one of the most serious infectious diseases. Many adolescents around the world are sexually...
Published by: IJHS Medical Association
Sentiment Analysis on Movie Reviews Dataset Using Support Vector Machines and Ensemble Learning
The internet makes it easier for people to connect to each other and has become a platform to express ideas and share information with the world. The growth of the internet has indirectly led to the development of social...
Published by: IGI Global Scientific Publishing
Right sided eventration of diaphragm with clinodactyly
A. Sareen and K. Mahajan
Apr 21, 2015
Diaphragmatic hernia can be of two types-absence or deficiency of the diaphragm, or eventration resulting in elevation of a portion of the diaphragm as a result of incomplete muscularization. Complete eventration almost...
Published by: IJHS Medical Association
Knowledge and Attitude among High School Students towards HIV / AIDS in Rural areas of Belagavi–A Cross Sectional Study
Asha A. Bellad and Rajesh R Kulkarni
Mar 25, 2015
Introduction Since its emergence in 1981, the HIV/AIDS pandemic, which poses a serious challenge to mankind, without doubt, has become one of the most serious infectious diseases. Many adolescents around the world are sexually...
Published by: IJHS Medical Association
Sustainable Supply Chain Management Practices in Ghana
The study assessed the sustainable supply chain management (SSCM) practices of 303 manufacturing firms in Ghana with an annual turnover of not less than $1,000,000, which were purposively selected for the study. A questionnaire...
Published by: Indonesia Strategic Sustainability
Right sided eventration of diaphragm with clinodactyly
A. Sareen and K. Mahajan
Apr 21, 2015
Diaphragmatic hernia can be of two types-absence or deficiency of the diaphragm, or eventration resulting in elevation of a portion of the diaphragm as a result of incomplete muscularization. Complete eventration almost...
Published by: IJHS Medical Association
Mice expressing an error-prone DNA polymerase in mitochondria display elevated replication pausing and chromosomal breakage at fragile sites of mitochondrial DNA.
Laura J Bailey, Tricia J Cluett, Aurelio Reyes, Tom A Prolla, Joanna Poulton, Christiaan Leeuwenburgh, Ian J Holt
Nov 23, 2017
Expression of a proof-reading deficient form of mitochondrial DNA (mtDNA) polymerase gamma, POLG, causes early death accompanied by features of premature ageing in mouse. However, the mechanism of cellular senescence remains...
Physical Exercise (Riyazat) a Boon for Expecting Mothers
Creation has endowed the female of the species with the gift of pro-creation. Therefore this unique gift is the greatest happiness for a woman, who is aware that she and her kind are the ones who have brought mankind in this...
Published by: IJHS Medical Association
Students' Performance Prediction in Higher Education Using Multi-Agent Framework-Based Distributed Data Mining Approach
An effective educational program warrants the inclusion of an innovative construction that enhances the higher education efficacy in such a way that accelerates the achievement of desired results and reduces the risk of...
Published by: IGI Global Scientific Publishing
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