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Animals Antineoplastic Combined Chemotherapy Protocols Benzamides Breast Neoplasms Cell Line Tumor Cell Proliferation Cyclin-Dependent Kinase 4 Cyclin-Dependent Kinase 6 E2F Transcription Factors Female Humans MCF-7 Cells Mice SCID Morpholines Piperazines Pyridines Pyrimidines Receptors Estrogen TOR Serine-Threonine Kinases Xenograft Model Antitumor Assays

In 2011, a governmental initiative driven by the Department for Business Innovation and Skills invited the British Standards Institute (BSI) to write and publish a publicly available specification (PAS) for the reuse of waste...

One route to reducing electronic waste, increasing product reuse, is dependent on the quality and functionality of discarded electronic goods (core), about which little is known or understood. This paper reports on the...

Fetus Imaging Pregnancy Radiology staging

Is it possible to say something positive about Internet filtering in libraries and not have everyone, including your mother, call you a wild-eyed, hidebound, neo-Nazi bashi-bazouk? No, of course not, but I'm going to try to...

Internet Filtering libraries First Amendment pornography Library and Information Science

One route to reducing electronic waste, increasing product reuse, is dependent on the quality and functionality of discarded electronic goods (core), about which little is known or understood. This paper reports on the...

Patients’ emotions toward health IT can play an important role in explaining their usage of it. One form of health IT is self-managing care IT, such as activity trackers that can be used by chronic patients to adopt a healthy...

End-User Computing Computer Science and Information Technology Human-Computer Interaction

In 2011, a governmental initiative driven by the Department for Business Innovation and Skills invited the British Standards Institute (BSI) to write and publish a publicly available specification (PAS) for the reuse of waste...

Investors typically build portfolios for retirement. Investment portfolios are typically based on four asset classes that are commonly managed by large investment firms. The research presented in this article involves the...

Business Information Systems Business and Management Operations and Service Management

This study aimed to formulate antibacterial dental adhesives. Phosphate‐substituted methacrylate adhesives were modified with 0–20 wt % copper‐doped glass microparticles. Two shapes of microparticles were used: regular shaped...

Adhesives biomaterials biomedical applications

This study aimed to formulate antibacterial dental adhesives. Phosphate‐substituted methacrylate adhesives were modified with 0–20 wt % copper‐doped glass microparticles. Two shapes of microparticles were used: regular shaped...

Adhesives biomaterials biomedical applications

Betacoronavirus covid-19 Coronavirus Infections Databases Genetic genetic variation Genome Viral Humans Internet Pandemics Pneumonia Viral SARS-CoV-2 Spike Glycoprotein Coronavirus

ZSM-5 was evaluated for chemical production in a reaction mixture consisting of palmitic acid and water at conditions near the critical point of water (400 °C, 23 ± 2 MPa). Two types of ZSM-5, a microscale variety with particle...

BTEX aromatic hydrocarbons pressurized water Zeolites

Understanding the role of Tau protein aggregation in the pathogenesis of Alzheimer's disease is critical for the development of new Tau-based therapeutic strategies to slow or prevent dementia. We tested the hypothesis that Tau...

Alzheimer's Disease Connectivity Graph theory MEG PET Tau Aged Aged 80 and over Alzheimer Disease Cognition Female Humans Magnetoencephalography Male Middle Aged Molecular Imaging Occipital Lobe Parietal Lobe Positron-Emission Tomography protein aggregation Pathological Synaptic Transmission tau Proteins

ZSM-5 was evaluated for chemical production in a reaction mixture consisting of palmitic acid and water at conditions near the critical point of water (400 °C, 23 ± 2 MPa). Two types of ZSM-5, a microscale variety with particle...

BTEX aromatic hydrocarbons pressurized water Zeolites

BACKGROUND: Combining PET amyloid-β (Aβ) and tau imaging may be critical for tracking disease progression in Alzheimer's disease (AD). OBJECTIVE: We sought to characterize the relationship between Aβ and tau ligands as well as...

Alzheimer’s disease Amyloid beta-Peptides Cerebrospinal Fluid Proteins positron emission tomography tau Proteins Aged aging Alzheimer Disease Amyloid beta-Peptides Analysis of Variance Aniline Compounds Carbolines Cognition Disorders Ethylene Glycols Female Humans Male Neuropsychological Tests Positron-Emission Tomography Psychiatric Status Rating Scales tau Proteins

Increased mitochondrial reactive oxygen species (ROS), particularly superoxide have been suggested to mediate hypoxic pulmonary vasoconstriction (HPV), chronic hypoxia-induced pulmonary hypertension (PH) and right ventricular...

1102 Cardiorespiratory Medicine and Haematology Lung Cardiovascular

Current genetic data are equivocal as to whether goat domestication occurred multiple times or was a singular process. We generated genomic data from 83 ancient goats (51 with genome-wide coverage) from Paleolithic to Medieval...

Africa Animals Animals Domestic Asia DNA Ancient DNA Mitochondrial domestication Europe Follistatin genetic variation Genome Goats Mosaicism Phylogeny

Optogenetics has revolutionized neuroscience in small laboratory animals, but its effect on animal models more closely related to humans, such as non-human primates (NHPs), has been mixed. To make evidence-based decisions in...

gene therapy monkey Monkeys Non-human primates nonhuman primates Open Science Optical control Optogenetic optogenetics Viral vectors Animals Brain Neurons Neurosciences optogenetics Primates