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Cover Image for Brain responses to different types of salience in antipsychotic naïve first episode psychosis View Article
Brain responses to different types of salience in antipsychotic naïve first episode psychosis
Franziska Knolle, Anna O Ermakova, Azucena Justicia, Paul C Fletcher, Nico Bunzeck, Emrah Düzel, Graham K Murray
Oct 03, 2018
Abnormal salience processing has been suggested to contribute to the formation of positive psychotic symptoms in schizophrenia and related conditions. Previous research utilising reward learning or anticipation paradigms has...
Adolescent Adult Amygdala Antipsychotic Agents Applied Behavior Analysis Brain Mapping Case-Control Studies Female Gyrus Cinguli Humans Magnetic Resonance Imaging Male motivation Photic Stimulation Reward Schizophrenia Substantia Nigra Ventral Tegmental Area Young Adult
Cover Image for Abnormal reward prediction-error signalling in antipsychotic naive individuals with first-episode psychosis or clinical risk for psychosis. View Article
Abnormal reward prediction-error signalling in antipsychotic naive individuals with first-episode psychosis or clinical risk for psychosis.
Anna O Ermakova, Franziska Knolle, Azucena Justicia, Edward T Bullmore, Peter B Jones, Trevor W Robbins, Paul C Fletcher, Graham K Murray
Jun 04, 2018
Ongoing research suggests preliminary, though not entirely consistent, evidence of neural abnormalities in signalling prediction errors in schizophrenia. Supporting theories suggest mechanistic links between the disruption of...
Anticipation Psychological Brain Brain Mapping Female Humans Magnetic Resonance Imaging Male Neural Pathways Prodromal Symptoms Psychotic Disorders Reward risk Young Adult
Cover Image for Analysis of the role of the Rac/Cdc42 GTPases during planar cell polarity generation in <em>Drosophila</em> View Article
Analysis of the role of the Rac/Cdc42 GTPases during planar cell polarity generation in <em>Drosophila</em>
Silvia Munoz-Descalzo, Azucena Gomez-Cabrero, Marek Mlodzik, Nuria Paricio
Jan 01, 0001
Initial genetic studies in Drosophila suggested that several members of the Rho subfamily (RhoA, Rac1 and Cdc42) are involved in planar cell polarity (PCP) establishment. However, analyses of Rac1, Rac2 and Mtl loss-of-function...
Cover Image for Analysis of the role of the Rac/Cdc42 GTPases during planar cell polarity generation in <em>Drosophila</em> View Article
Analysis of the role of the Rac/Cdc42 GTPases during planar cell polarity generation in <em>Drosophila</em>
Silvia Munoz-Descalzo, Azucena Gomez-Cabrero, Marek Mlodzik, Nuria Paricio
Jan 01, 0001
Initial genetic studies in Drosophila suggested that several members of the Rho subfamily (RhoA, Rac1 and Cdc42) are involved in planar cell polarity (PCP) establishment. However, analyses of Rac1, Rac2 and Mtl loss-of-function...
Cover Image for An Autocatalytic System of Photooxidation-Driven Substitution Reactions on a Fe<sup>II</sup><sub>4</sub>L<sub>6</sub>Cage Framework View Article
An Autocatalytic System of Photooxidation-Driven Substitution Reactions on a Fe<sup>II</sup><sub>4</sub>L<sub>6</sub>Cage Framework
Prakash P Neelakandan, Azucena Jiménez, John D Thoburn, Jonathan R Nitschke
Sep 29, 2015
Self-assembly metal-organic capsules photosensitizers autocatalysis
Cover Image for Altered subcortical emotional salience processing differentiates Parkinson’s patients with and without psychotic symptoms View Article
Altered subcortical emotional salience processing differentiates Parkinson’s patients with and without psychotic symptoms
Franziska Knolle, A Justicia, G Arrondo, C Tudor-Sfetea, Roger Barker, GK Murray
May 13, 2020
Adult Aged Amygdala Brain Diagnosis Differential Emotions Female Humans Magnetic Resonance Imaging Male Middle Aged Parkinson Disease Psychotic Disorders Schizophrenia
Cover Image for TNFα Impairs Rhabdoviral Clearance by Inhibiting the Host Autophagic Antiviral Response. View Article
TNFα Impairs Rhabdoviral Clearance by Inhibiting the Host Autophagic Antiviral Response.
Raquel Espín-Palazón, Alicia Martínez-López, Francisco J Roca, Azucena López-Muñoz, Sylwia D Tyrkalska, Sergio Candel, Diana García-Moreno, Alberto Falco, José Meseguer, Amparo Estepa, Victoriano Mulero
May 13, 2019
TNFα is a pleiotropic pro-inflammatory cytokine with a key role in the activation of the immune system to fight viral infections. Despite its antiviral role, a few viruses might utilize the host produced TNFα to their benefit....
Animals Autophagy Blotting Western Disease Models Animal Fluorescent Antibody Technique host-parasite interactions Organisms Genetically Modified Polymerase Chain Reaction rhabdoviridae Rhabdoviridae Infections Tumor Necrosis Factor-alpha Virus Replication Zebrafish
Cover Image for Cortical and Striatal Reward Processing in Parkinson's Disease Psychosis View Article
Cortical and Striatal Reward Processing in Parkinson's Disease Psychosis
S Garofalo, A Justicia, G Arrondo, AO Ermakova, P Ramachandra, C Tudor-Sfetea, TW Robbins, RA Barker, PC Fletcher, GK Murray
Jul 03, 2017
fMRI posterior cingulate cortex prediction error reinforcement learning Ventral Striatum