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Results: 36
Evolutionary genomics of Staphylococcus aureus reveals insights into the origin and molecular basis of ruminant host adaptation
CM Guinane, NL Ben Zakour, MA Tormo-Mas, LA Weinert, BV Lowder, RA Cartwright, DS Smyth, CJ Smyth, JA Lindsay, KA Gould, A Witney, J Hinds, JP Bollback, A Rambaut, JR Penadés, JR Fitzgerald
Apr 12, 2017
Investigating the role of restoration plantings in introducing disease—a case study using phytophthora
Translocating plants to natural habitats is a long-standing conservation practice but is growing in magnitude to deliver international targets to mitigate climate change and reverse biodiversity loss. Concurrently...
The Segond fracture occurs at the site of lowest sub-entheseal trabecular bone volume fraction on the tibial plateau.
William Mullins, Gavin E Jarvis, Daniel Oluboyede, Linda Skingle, Ken Poole, Tom Turmezei, Cecilia Brassett
Jul 13, 2020
In a series of human cadaveric experiments, Dr. Paul Segond first described the avulsion injury occurring at the anterolateral tibial plateau that later took his name. The fracture is thought to arise as a consequence of...
Examining the Phagocytic Activity of HIV-1 Tat Exposed Microglia: Possible Chemokine Receptor Activation
Joshua T Straka
Jan 01, 0001
Anti-retroviral therapy (ART) has been successful in increasing the survival rate of HIV-infected patients, however the incidence of moderate cognitive impairment among patients remains high. The occurrence of HIV-Associated...
Published by: Ursinus College
Structure and rigidity of functions in BVloc2(R2) with gradients taking only three values
Roger Moser
Apr 06, 2018
Consider a function u ∈ BV 2 loc(R 2 such that ∇u takes values in a fixed set of three vectors almost everywhere. This condition implies that u is piecewise affine away from a closed set of...
Dynamic cerebral autoregulation estimates derived from near infrared spectroscopy and transcranial Doppler are similar after correction for transit time and blood flow and blood volume oscillations.
We analysed mean arterial blood pressure, cerebral blood flow velocity, oxygenated haemoglobin and deoxygenated haemoglobin signals to estimate dynamic cerebral autoregulation. We compared macrovascular (mean arterial blood...
Dynamic cerebral autoregulation group delay microvascular transit time near infrared spectroscopy Transcranial Doppler Adult Blood Flow Velocity blood pressure Blood Volume Cerebrovascular Circulation Female Hemodynamics Homeostasis Humans Hypercapnia Hypocapnia Male Oxyhemoglobins Rest spectroscopy Near-Infrared Ultrasonography Doppler Transcranial
Evidence for Ongoing Modeling-Based Bone Formation in Human Femoral Head Trabeculae via Forming Minimodeling Structures
Hiroshige Sano, Naoki Kondo, Taketoshi Shimakura, Junichi Fujisawa, Yasufumi Kijima, Tomotake Kanai, Kenneth ES Poole, Noriaki Yamamoto, Hideaki E Takahashi, Naoto Endo
May 15, 2018
Bone modeling is a biological process of bone formation that adapts bone size and shape to mechanical loads, especially during childhood and adolescence. Bone modeling in cortical bone can be easily detected using sequential...
BHDPC Is a Novel Neuroprotectant That Provides Anti-neuroinflammatory and Neuroprotective Effects by Inactivating NF-κB and Activating PKA/CREB.
Chuwen Li, Tongkai Chen, Hefeng Zhou, Yu Feng, Maggie PM Hoi, Dan Ma, Chao Zhao, Ying Zheng, Simon MY Lee
Oct 03, 2018
Microglia-mediated neuroinflammatory responses are inevitable and important pathological processes in several kinds of disorder of the central nervous system (CNS). Therefore, alleviating activated microglia-induced inflammatory...
Preoperative breast radiation therapy
SV Lightowlers, LJ Boersma, A Fourquet, YM Kirova, BV Offersen, P Poortmans, AN Scholten, N Somaiah, CE Coles
Nov 24, 2017
Preoperative breast radiation therapy (RT) is not a new concept, but older studies failed to change practice. More recently, there has been interest in revisiting preoperative RT using modern techniques. This current perspective...
Cadmium body burden and increased blood pressure in middle-aged American Indians
N Franceschini, RC Fry, P Balakrishnan, A Navas-Acien, C Oliver-Williams, AG Howard, SA Cole, K Haack, EM Lange, BV Howard, LG Best, KA Francesconi, W Goessler, JG Umans, M Tellez-Plaza
Jun 13, 2017
Structure and rigidity of functions in BVloc2(R2) with gradients taking only three values
Roger Moser
Apr 06, 2018
Consider a function u ∈ BV 2 loc(R 2 such that ∇u takes values in a fixed set of three vectors almost everywhere. This condition implies that u is piecewise affine away from a closed set of...
CD33M inhibits microglial phagocytosis, migration and proliferation, but the Alzheimer's disease-protective variant CD33m stimulates phagocytosis and proliferation, and inhibits adhesion.
CD33 is a Siglec (sialic acid-binding immunoglobulin-type lectin) receptor on microglia. Human CD33 can be alternatively spliced into two isoforms: the long isoform (CD33M) and a shorter isoform (CD33m) that lacks the sialic...
Alzheimer's Disease CD33 Microglia Neuroinflammation Siglec-3 Alzheimer Disease Animals Cell Adhesion Cell Line Cell Movement Cell Proliferation Encephalitis Gene Knockdown Techniques genetic variation Humans Mice Microglia Neuraminidase Phagocytosis RNA Interference Sialic Acid Binding Ig-like Lectin 3
The Financial Impact on Reimbursement of Moderately Hypofractionated Postoperative Radiation Therapy for Breast Cancer
GN Marta, D Ramiah, O Kaidar-Person, A Kirby, C Coles, R Jagsi, T Hijal, G Sancho, Y Zissiadis, J-P Pignol, AY Ho, SH-C Cheng, BV Offersen, I Meattini, P Poortmans
Jan 06, 2021
AIMS: Moderately hypofractionated breast irradiation has been evaluated in several prospective studies, resulting in wide acceptance of shorter treatment protocols for postoperative breast irradiation. Reimbursement for...
Modulation of Microglial Phagocytic Activity and Cytoskeletal Proteins Through HIV-1 Tat Induced Neuroinflammation
Courtney Burns
Jan 01, 0001
Neuroinflammation, the activation of the brain's innate immune system in response to inflammatory challenges, is characterized by a host of cellular and molecular changes within the central nervous system. During...
Neuroinflammation Microglia Phagocytosis Cytoskeleton HIV-1 Tat neurodegeneration Biology Immune System Diseases Life Sciences Nervous System Diseases Neurosciences Virus Diseases
Published by: Ursinus College
On the Hughes' model for pedestrian flow
In this paper we investigate the mathematical theory of Hughes' model for the flow of pedestrians (cf. Hughes (2002) [17]), consisting of a non-linear conservation law for the density of pedestrians coupled with an eikonal...
A system of interaction and structure V
System NEL is the mixed commutative/non-commutative linear logic BV augmented with linear logic's exponentials, or, equivalently, it is MELL augmented with the non-commutative self-dual connective seq. NEL is presented in deep...
Lipopolysaccharide activates microglia via neuraminidase 1 desialylation of Toll-like Receptor 4.
Most cell surface receptors are sialylated, i.e. have sialic acid as the terminal residue of their sugar chains, but can be desialylated by sialidases, such as neuraminidase 1 (Neu1). Desialylation by Neu1 can activate immune...
A system of interaction and structure V
System NEL is the mixed commutative/non-commutative linear logic BV augmented with linear logic's exponentials, or, equivalently, it is MELL augmented with the non-commutative self-dual connective seq. NEL is presented in deep...
Understanding conflict among experts working on controversial species
V Donfrancesco, BL Allen, R Appleby, L Behrendorff, G Conroy, MS Crowther, CR Dickman, T Doherty, BA Fancourt, CE Gordon, SM Jackson, CN Johnson, MS Kennedy, L Koungoulos, M Letnic, LKP Leung, KJ Mitchell, B Nesbitt, T Newsome, C Pacioni, J Phillip, BV Purcell, EG Ritchie, BP Smith, D Stephens, J Tatler, LM van Eeden, KM Cairns
Feb 10, 2023
On the Hughes' model for pedestrian flow
In this paper we investigate the mathematical theory of Hughes' model for the flow of pedestrians (cf. Hughes (2002) [17]), consisting of a non-linear conservation law for the density of pedestrians coupled with an eikonal...
Explaining negative kin discrimination in a cooperative mammal society.
Faye J Thompson, Michael A Cant, Harry H Marshall, Emma IK Vitikainen, Jennifer L Sanderson, Hazel J Nichols, Jason S Gilchrist, Matthew BV Bell, Andrew J Young, Sarah J Hodge, Rufus A Johnstone
Jan 07, 2021
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