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Second messenger analogues highlight unexpected substrate sensitivity of CD38
The multifunctional, transmembrane glycoprotein human CD38 catalyses the synthesis of three key Ca2+-mobilising messengers, including cyclic adenosine 5′-diphosphate ribose (cADPR), and CD38 knockout studies have...
Second messenger analogues highlight unexpected substrate sensitivity of CD38
The multifunctional, transmembrane glycoprotein human CD38 catalyses the synthesis of three key Ca2+-mobilising messengers, including cyclic adenosine 5′-diphosphate ribose (cADPR), and CD38 knockout studies have...
Winter is coming
Sanja Bojic, Alex Murray, Barry L Bentley, Ralf Spindler, Piotr Pawlik, José L Cordeiro, Roman Bauer, João Pedro de Magalhães
Mar 24, 2021
The preservative effects of low temperature on biological materials have been long recognised, and cryopreservation is now widely used in biomedicine, including in organ transplantation, regenerative medicine and drug discovery....
Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4'-Phosphopantothenoyl-l-cysteine Synthetase (CoaB) Activity.
Joanna C Evans, Dinakaran Murugesan, John M Post, Vitor Mendes, Zhe Wang, Navid Nahiyaan, Sasha L Lynch, Stephen Thompson, Simon R Green, Peter C Ray, Jeannine Hess, Christina Spry, Anthony G Coyne, Chris Abell, Helena IM Boshoff, Paul G Wyatt, Kyu Y Rhee, Tom L Blundell, Clifton E Barry, Valerie Mizrahi
May 10, 2021
Coenzyme A (CoA) is a ubiquitous cofactor present in all living cells and estimated to be required for up to 9% of intracellular enzymatic reactions. Mycobacterium tuberculosis (Mtb) relies on its own ability to biosynthesize...
The Multilayer Connectome of Caenorhabditis elegans.
Barry Bentley, Robyn Branicky, Christopher L Barnes, Yee Lian Chew, Eviatar Yemini, Edward T Bullmore, Petra E Vértes, William R Schafer
Nov 23, 2017
Connectomics has focused primarily on the mapping of synaptic links in the brain; yet it is well established that extrasynaptic volume transmission, especially via monoamines and neuropeptides, is also critical to brain function...
Ursinus College Alumni Journal, July 1961
Richard T. Schellhase, J. William D. Wright, Calvin D. Yost, Roger P. Staiger, Raymond V. Gurzynski, Blanche B. Schultz, Donald L. Helfferich, H. Lloyd Jones, Jane R. Estabrook, Charles David Mattern, Morton J. Oppenheimer
Jan 01, 0001
The President writes Thirty years of champions and their coach Were we wrong about the Victorians? A view of Vietnam A philosopher looks at Barry Goldwater The alumni seminar Dr. Paisley dies William D. Reimert elected...
Ursinus College Collegeville Pennsylvania alumni Deaths Marriages Eleanor Frost Snell Vietnam Barry Goldwater Harry E. Paisley William D. Reimert Norman E. McClure John Richardson Peirce Morton J. Oppenheimer Harry L. Showalter track team baseball tennis Clarence A. Warden Jr. Alfred L. Creager Higher Education Social History United States History
Published by: Ursinus College
Hydration and N-acetyl-l-cysteine alter the microstructure of human nail and bovine hoof
This work aimed to (a) characterize the microstructure and porosity of human nail and bovine hoof by mercury intrusion porosimetry and SEM image analysis, (b) study the effects of hydration and of N-acetyl-l-cysteine treatment...
Corinna PMG 655 (= P.Oxy. 2370) fr.1 l. 13 κόσμ[εισα λόγυ]ς
L Prauscello
May 02, 2017
0. Fr. 1 of P.Oxy. 2370 (= MP3
249; LDAB 573), published by Lobel in 1956, is so far the only papyrus
fragment among those extant in Boeotian dialect1
whose authorship can be securely ascribed to
Corinna thanks to the overlap...
Floer Simple Manifolds and L-Space Intervals
An oriented three-manifold with torus boundary admits either no L-space Dehn filling, a unique L-space filling, or an interval of L-space fillings. In the latter case, which we call “Floer simple,” we construct an invariant...
Hydration and N-acetyl-l-cysteine alter the microstructure of human nail and bovine hoof
This work aimed to (a) characterize the microstructure and porosity of human nail and bovine hoof by mercury intrusion porosimetry and SEM image analysis, (b) study the effects of hydration and of N-acetyl-l-cysteine treatment...
Eugene L. Opie, 1910
The Rockefeller University
Jan 01, 0001
Eugene L. Opie, M.D. Inflammation
Lecture delivered February 10th, 1910
Bacterial Infection inflammation reaction macrophage Lymphatic Vessels polynuclear leucocytes enzyme
Published by: J.B. Lippincott Company
L q -spectra of self-affine measures
Abstract: We study L q -spectra of planar self-affine measures generated by diagonal matrices. We introduce a new technique for constructing and understanding examples based on combinatorial estimates for the exponential growth...
S-2-Amino-4-cyanobutanoic acid (β-cyanomethyl-L-Ala) as an atom-efficient solubilising synthon for L-glutamine
Glutamine (Gln) is often a difficult amino acid to incorporate during solution-phase peptide synthesis, owing to poor solubility and unwanted dehydrations as side-reactions. Current approaches to solving these problems are...
The Ursinus Weekly, November 18, 1940
Johnson depicts the Ursinus grad as a substantial citizen Forum completing plans for Wallace's address McClure tells Bath parish of "work of Christian college" Class of '41 meets to perfect weekend plans Tyson will speak to...
Ursinus College Collegeville Pennsylvania newspaper Russell Johnson Norman E. McClure George R. Tyson Lawrence B. Rentschler debate team International Relations Club Sprankle Hall J. Howard Graham Nevin C. Harner Henry A. Wallace Women's Club Natalie Hogeland Soccer Football field hockey Franklin I. Sheeder cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Frank L. Horsfall, Jr., 1952
The Rockefeller University
Jan 01, 0001
Frank L. Horsfall, Jr. Experiments on chemical alteration of virus infections.
Lecture delivered November 20, 1952
Posted with permission
Published by: Academic Press Inc., Publishers
Rapid sensing of l-leucine by human and murine hypothalamic neurons
Nicholas Heeley, Peter Kirwan, Tamana Darwish, Marion Arnaud, Mark L Evans, Florian T Merkle, Frank Reimann, Fiona M Gribble, Clemence Blouet
Apr 05, 2018
OBJECTIVE: Dietary proteins are sensed by hypothalamic neurons and strongly influence multiple aspects of metabolic health, including appetite, weight gain, and adiposity. However, little is known about the mechanisms by which...
S-2-Amino-4-cyanobutanoic acid (β-cyanomethyl-L-Ala) as an atom-efficient solubilising synthon for L-glutamine
Glutamine (Gln) is often a difficult amino acid to incorporate during solution-phase peptide synthesis, owing to poor solubility and unwanted dehydrations as side-reactions. Current approaches to solving these problems are...
Microbial regulation of the L cell transcriptome.
Tulika Arora, Rozita Akrami, Ramona Pais, Linda Bergqvist, Bengt R Johansson, Thue W Schwartz, Frank Reimann, Fiona M Gribble, Fredrik Bäckhed
Apr 26, 2018
L cells are an important class of enteroendocrine cells secreting hormones such as glucagon like peptide-1 and peptide YY that have several metabolic and physiological effects. The gut is home to trillions of bacteria affecting...
Dr. Herman L. Frick Promotion
Winthrop News Service
Jan 01, 0001
Dr. Herman L. Frick, superintendent of Winthrop Training School, was named Director of Teacher Education and Graduate Study at Winthrop in October 1946 Dr. Frick worked at Winthrop from 1941 to 1949 except for 1944-1946 when he...
Winthrop College of Education Winthrop Training School Higher Education Teacher Education and Professional Development
Published by: Winthrop University
Review of David Bentley Hart, The Experience of God: Being, Consciousness, Bliss (New Haven and London
Michelle Rebidoux
May 16, 2016
One thing, certainly, can be said about David Bentley Hart’s book and it is this: that its author takes atheism very seriouslyor rather, the “New Atheism,” as it is called, a recent ideologico-cultural “movement” whose...
Published by: Memorial University of Newfoundland
Review of David Bentley Hart, The Experience of God: Being, Consciousness, Bliss (New Haven and London
Michelle Rebidoux
May 16, 2016
One thing, certainly, can be said about David Bentley Hart’s book and it is this: that its author takes atheism very seriouslyor rather, the “New Atheism,” as it is called, a recent ideologico-cultural “movement” whose...
Published by: Memorial University of Newfoundland
Amygdala volume and hypothalamic-pituitary-adrenal axis reactivity to social stress
Tom J. Barry, Lynne Murray, Pasco Fearon, Christina Moutsiana, Tom Johnstone, Sarah L. Halligan
Nov 01, 2017
The amygdala plays a central role in emotional processing and has an activating influence on the hypothalamic-pituitary-adrenal (HPA) axis. Structural changes in the amygdala have been associated with early adversity and, in...
Amygdala Cortisol Depression hypothalamic-pituitary-adrenal axis Stress sensitivity /dk/atira/pure/subjectarea/asjc/2700/2712 name=Endocrinology, Diabetes and Metabolism /dk/atira/pure/subjectarea/asjc/1300/1310 name=Endocrinology /dk/atira/pure/subjectarea/asjc/2800/2807 name=Endocrine and Autonomic Systems /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/subjectarea/asjc/2800/2803 name=Biological Psychiatry /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
L(3)mbt and the LINT complex safeguard cellular identity in the Drosophila ovary.
Maintenance of cellular identity is essential for tissue development and homeostasis. At the molecular level, cell identity is determined by the coordinated activation and repression of defined sets of genes. The tumor...
L<sup>q</sup>-spectra of self-affine measures
Abstract
We study L
q
-spectra of planar...
L<sup>q</sup>-spectra of self-affine measures
Abstract
We study L
q
-spectra of planar...
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