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Subclassifying ANCA-associated vasculitis
This editorial refers to Clinical impact of subgrouping
ANCA-associated vasculitis according to antibody
specificity beyond the clinicopathological classification,
Deshayes et al.
Allograft rejection is associated with development of functional IgE specific for donor MHC antigens.
Andreas M Farkas, Ulrike Baranyi, Georg A Böhmig, Lukas Unger, Stefan Hopf, Markus Wahrmann, Heinz Regele, Benedikt Mahr, Christoph Schwarz, Karin Hock, Nina Pilat, Ivan Kristo, Jasmin Mraz, Christian Lupinek, Josef Thalhamer, Gregor Bond, Lorenz Kuessel, Elizabeth Wlodek, Jack Martin, Menna Clatworthy, Gavin Pettigrew, Rudolf Valenta, Thomas Wekerle
Dec 17, 2018
BACKGROUND: Donor-specific antibodies of the IgG isotype are measured routinely for diagnostic purposes in renal transplant recipients and are associated with antibody-mediated rejection and long-term graft loss. OBJECTIVE: This...
IgE Transplantation alloreactivity donor-specific antibodies humoral rejection immunology Allografts Animals Female Graft Rejection Heart Transplantation Histocompatibility Antigens Class I Histocompatibility Antigens Class II Humans Immunoglobulin E Immunoglobulin G Kidney Transplantation Male Mice Mice Inbred BALB C Skin Transplantation
Morgan's canon is not evidence
Mahr & Csibra's (M&C's) account of the communicative function of episodic memory relies more heavily on the case against episodic memory in nonhumans than their description suggests. Although the communicative function of...
<em>Homo homini lupus</em>? Explaining antisocial punishment
Punishing group members who parasitize their own group’s resources is an almost universal human behavior, as evidenced by multiple cross-cultural and theoretical studies. Recently, researchers in social and behavioral sciences...
Constructing illoyal algebra-valued models of set theory
Abstract An algebra-valued model of set theory is called loyal to its algebra if the model and its algebra have the same propositional logic; it is called...
Sustained neural rhythms reveal endogenous oscillations supporting speech perception
Rhythmic sensory or electrical stimulation will produce rhythmic brain responses. These rhythmic responses are often interpreted as endogenous neural oscillations aligned (or “entrained”) to the stimulus rhythm. However...
Sustained neural rhythms reveal endogenous oscillations supporting speech perception.
Rhythmic sensory or electrical stimulation will produce rhythmic brain responses. These rhythmic responses are often interpreted as endogenous neural oscillations aligned (or "entrained") to the stimulus rhythm. However...
Volunteer Conservation Action Data Reveals Large-Scale and Long-Term Negative Population Trends of a Widespread Amphibian, the Common Toad (Bufo bufo).
Rare and threatened species are the most frequent focus of conservation science and action. With the ongoing shift from single-species conservation towards the preservation of ecosystem services, there is a greater need to...
Phase Entrainment of Brain Oscillations Causally Modulates Neural Responses to Intelligible Speech.
Due to their periodic nature, neural oscillations might represent an optimal "tool" for the processing of rhythmic stimulus input [1-3]. Indeed, the alignment of neural oscillations to a rhythmic stimulus, often termed phase...
Transcranial electric stimulation for the investigation of speech perception and comprehension.
Transcranial electric stimulation (tES), comprising transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS), involves applying weak electrical current to the scalp, which can be...
How to test for phasic modulation of neural and behavioural responses.
Research on whether perception or other processes depend on the phase of neural oscillations is rapidly gaining popularity. However, it is unknown which methods are optimally suited to evaluate the hypothesized phase effect....
<em>Homo homini lupus</em>? Explaining antisocial punishment
Punishing group members who parasitize their own group’s resources is an almost universal human behavior, as evidenced by multiple cross-cultural and theoretical studies. Recently, researchers in social and behavioral sciences...
Constructing illoyal algebra-valued models of set theory
Abstract: An algebra-valued model of set theory is called loyal to its algebra if the model and its algebra have the same propositional logic; it is called faithful if all elements of the algebra are truth values of a sentence...
Inverse-Designed Narrowband THz Radiator for Ultrarelativistic Electrons.
Benedikt Hermann, Urs Haeusler, Gyanendra Yadav, Adrian Kirchner, Thomas Feurer, Carsten Welsch, Peter Hommelhoff, Rasmus Ischebeck
May 30, 2022
THz radiation finds various applications in science and technology. Pump-probe experiments at free-electron lasers typically rely on THz radiation generated by optical rectification of ultrafast laser pulses in electro-optic...
WildLab
Neural mechanisms of face perception are predominantly studied in well-controlled experimental settings that involve random stimulus sequences and fixed eye positions. Although powerful, the employed paradigms are far from what...
The COVID-19 pandemic and ANCA-associated vasculitis - reports from the EUVAS meeting and EUVAS education forum.
Andreas Kronbichler, Duvuru Geetha, Rona M Smith, Allyson C Egan, Ingeborg M Bajema, Ulf Schönermarck, Alfred Mahr, Hans-Joachim Anders, Annette Bruchfeld, Maria C Cid, David RW Jayne
Jan 06, 2022
The Coronavirus Disease 2019 (COVID-19) pandemic influenced the management of patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis. A paucity of data exists on outcome of patients with vasculitis...
Cultured subventricular zone progenitor cells transduced with neurogenin-2 become mature glutamatergic neurons and integrate into the dentate gyrus.
Coronavirus Pseudotypes for All Circulating Human Coronaviruses for Quantification of Cross-Neutralizing Antibody Responses.
Alexander Thomas Sampson, Jonathan Heeney, Diego Cantoni, Matteo Ferrari, Maria Suau Sans, Charlotte George, Cecilia Di Genova, Martin Mayora Neto, Sebastian Einhauser, Benedikt Asbach, Ralf Wagner, Helen Baxendale, Nigel Temperton, George Carnell
Sep 28, 2021
The novel coronavirus SARS-CoV-2 is the seventh identified human coronavirus. Understanding the extent of pre-existing immunity induced by seropositivity to endemic seasonal coronaviruses and the impact of cross-reactivity on...
coronavirus neutralization pseudotyped virus covid-19 SARS-CoV-2 Cell Line Animals Humans Coronavirus 229E Human Coronavirus OC43 Human Lentivirus Antibodies Viral Neutralization Tests Transfection Cross Reactions Plasmids Virus Internalization Coronavirus NL63 Human Spike Glycoprotein Coronavirus Middle East Respiratory Syndrome Coronavirus Broadly Neutralizing Antibodies covid-19 SARS-CoV-2
Published by: Viruses
The deubiquitylating enzyme UCHL3 regulates Ku80 retention at sites of DNA damage.
Ryotaro Nishi, Paul WG Wijnhoven, Yusuke Kimura, Misaki Matsui, Rebecca Konietzny, Qian Wu, Keisuke Nakamura, Tom L Blundell, Benedikt M Kessler
Feb 14, 2019
Developing a composite outcome tool to measure response to treatment in ANCA-associated vasculitis
Kaitlin A Quinn, Sara Monti, Robin Christensen, David Jayne, Carol A Langford, Georgia E Lanier, Alfred Mahr, Christian Pagnoux, Beverley Shea, Peter Tugwell, Maria Bjork Viðarsdóttir, Gunnar Tomasson, Peter A Merkel
Nov 16, 2021
OBJECTIVE: The Outcome Measures in Rheumatology (OMERACT) Vasculitis Working Group aims to develop composite response criteria for ANCA-Associated Vasculitis (AAV). METHODS: The project follows the OMERACT approach for composite...
Network Interventions for Changing Physical Activity Behaviour in Preadolescents.
Antonios Proestakis, Eugenia Polizzi di Sorrentino, Helen Elizabeth Brown, Esther van Sluijs, Ankur Mani, Sandra Caldeira, Benedikt Herrmann
Nov 19, 2018
Network interventions can help achieve behavioural change by inducing peer-pressure in the network. However, inducing peer-pressure without considering the structure of the existing social network may render the intervention...
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