Search
Results: 2
High-dimensional changepoint estimation with heterogeneous missingness
We propose a new method for changepoint estimation in partially-observed,
high-dimensional time series that undergo a simultaneous change in mean in a
sparse subset of coordinates. Our first methodological contribution is...
Whole-genome analysis of diverse Chlamydia trachomatis strains identifies phylogenetic relationships masked by current clinical typing.
Simon R Harris, Ian N Clarke, Helena MB Seth-Smith, Anthony W Solomon, Lesley T Cutcliffe, Peter Marsh, Rachel J Skilton, Martin J Holland, David Mabey, Rosanna W Peeling, David A Lewis, Brian G Spratt, Magnus Unemo, Kenneth Persson, Carina Bjartling, Robert Brunham, Henry JC de Vries, Servaas A Morré, Arjen Speksnijder, Cécile M Bébéar, Maïté Clerc, Bertille de Barbeyrac, Julian Parkhill, Nicholas R Thomson
Sep 06, 2019
Chlamydia trachomatis is responsible for both trachoma and sexually transmitted infections, causing substantial morbidity and economic cost globally. Despite this, our knowledge of its population and evolutionary genetics is...
Bacterial Outer Membrane Proteins Base Sequence Chlamydia Infections Chlamydia trachomatis DNA Bacterial Gene Transfer Horizontal Genome Bacterial Humans Lymphogranuloma Venereum Molecular Sequence Data Phylogeny Plasmids Polymorphism Single Nucleotide RNA Ribosomal 16S Recombination Genetic Sequence Analysis DNA Trachoma