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Results: 238
A phase I trial of the γ-secretase inhibitor MK-0752 in combination with gemcitabine in patients with pancreatic ductal adenocarcinoma.
Natalie Cook, Bristi Basu, Donna-Michelle Smith, Aarthi Gopinathan, Jeffry Evans, William P Steward, Daniel Palmer, David Propper, Balaji Venugopal, Mirela Hategan, D Alan Anthoney, Lisa V Hampson, Michael Nebozhyn, David Tuveson, Hayley Farmer-Hall, Helen Turner, Robert McLeod, Sarah Halford, Duncan Jodrell
Sep 20, 2018
BACKGROUND: The Notch pathway is frequently activated in cancer. Pathway inhibition by γ-secretase inhibitors has been shown to be effective in pre-clinical models of pancreatic cancer, in combination with gemcitabine. METHODS...
Adult Aged Amyloid Precursor Protein Secretases Antineoplastic Combined Chemotherapy Protocols Bayes Theorem Benzene Derivatives Carcinoma Pancreatic Ductal Deoxycytidine Drug Administration Schedule Female Humans Infusions Intravenous Male Middle Aged Pancreatic Neoplasms Propionates Receptors Notch Signal Transduction Sulfones Gemcitabine
High resolution soft x-ray spectroscopy and the quest for the hot (5-10 MK) plasma in solar active regions
We discuss the diagnostics available to study the 5-10 MK plasma in the solar
corona, which is key to understanding the heating in the cores of solar active
regions. We present several simulated spectra, and show that...
Transcriptional characterization of human megakaryocyte polyploidization and lineage commitment.
Fizzah A Choudry, Frederik O Bagger, Iain C Macaulay, Samantha Farrow, Frances Burden, Carly Kempster, Harriet McKinney, Lars R Olsen, Ni Huang, Kate Downes, Thierry Voet, Rakesh Uppal, John F Martin, Anthony Mathur, Willem H Ouwehand, Elisa Laurenti, Sarah A Teichmann, Mattia Frontini
Mar 15, 2021
BACKGROUND: Megakaryocytes (MKs) originate from cells immuno-phenotypically indistinguishable from hematopoietic stem cells (HSCs), bypassing intermediate progenitors. They mature within the adult bone marrow and release...
Doctoral Education, Pedagogy, and Autoethnography
This special issue of the Morning Watch brings together papers written for a doctoral course in the Faculty of Education. As facilitators of ED 702A/B Advanced Research Methodology in Education, a core course in the Faculty of...
Published by: The Morning Watch: Educational and Social Analysis
Designing Learning Environments That Support Diverse Students' Needs in a Teacher Education Program
The need to design learning environments (virtual, hybrid, and face-to-face) that support racial and ethnic minority students' academic success has increased tremendously. The data presented here were collected via a...
Published by: IGI Global Scientific Publishing
Crowded at the Summit: The Future of Infectious Disease
The Rockefeller University
Jan 01, 0001
On January 26, 2001, The Rockefeller University presented Raymond and Beverly Sackler Lecture by Joshua Lederberg, Professor Emeritus (The Rockefeller University)
Published by: The Rockefeller University
Hematopoietic Stem Cell Heterogeneity Is Linked to the Initiation and Therapeutic Response of Myeloproliferative Neoplasms.
Jingyuan Tong, Ting Sun, Shihui Ma, Yanhong Zhao, Mankai Ju, Yuchen Gao, Ping Zhu, Puwen Tan, Rongfeng Fu, Anqi Zhang, Ding Wang, Di Wang, Zhijian Xiao, Jiaxi Zhou, Renchi Yang, Stephen J Loughran, Juan Li, Anthony R Green, Emery H Bresnick, Dong Wang, Tao Cheng, Lei Zhang, Lihong Shi
Feb 24, 2021
The implications of stem cell heterogeneity for disease pathogenesis and therapy are poorly defined. JAK2V617F+ myeloproliferative neoplasms (MPNs), harboring the same mutation in hematopoietic stem cells (HSCs), display diverse...
Doctoral Education, Pedagogy, and Autoethnography
This special issue of the Morning Watch brings together papers written for a doctoral course in the Faculty of Education. As facilitators of ED 702A/B Advanced Research Methodology in Education, a core course in the Faculty of...
Published by: The Morning Watch: Educational and Social Analysis
Analysis of microbial keratitis incidence, isolates and in-vitro antimicrobial susceptibility in the East of England
Malik Moledina, Harry W Roberts, Achyut Mukherjee, David Spokes, Dimitris Pimenides, Christopher Stephenson, Ramy Bassily, Madhavan S Rajan, James Myerscough
Feb 28, 2023
BACKGROUND/OBJECTIVES: To report the incidence, microbiological profile and in-vitro antimicrobial susceptibilities of microbial keratitis (MK) in the East of England (EoE) over a 6-year period. SUBJECTS/METHODS: A retrospective...
Emerging researcher pedagogies
This special edition of the Morning Watch is the second collection of papers from the Faculty of Education doctoral students who are participating in ED 702 A/B Advanced Research Methodology in Education in 2017/18. ED 702 is a...
Published by: The Morning Watch: Educational and Social Analysis
The Ursinus Weekly, November 15, 1943
We must not lose this peace, urges Miss Sigrid Schultz Who's Who honors Ursinus seniors Arsenic and Old Lace scores hit before two capacity audiences Middleton celebrates fifth year in Navy St. Luke's holds special services...
Ursinus College Collegeville Pennsylvania newspaper Curtain Club William Middleton Navy V-12 Sigrid Schultz Who's who debating club Arthur C. Ohl St. Luke's Reformed Church William H. Ludwick English Club Lantern student housing field hockey Soccer Women's Athletic Association cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The Ursinus Weekly, June 6, 1949
Record class receives diplomas today Helfferich speaks on "Brother Aaron" at seventy-ninth baccalaureate service Governor Driscoll addresses graduates at annual commencement day service Forty-one students win honors, prizes...
Ursinus College Collegeville Pennsylvania newspaper commencement Alfred E. Driscoll Reginald Helfferich Alfred Roberts Helen Pechter Harry E. Paisley Eugene H. Miller LIBRARY summer school student government Harry M. Frosberg Eugene Blum Alumni Association Reuben Sanchez baseball softball track team Ray Gurzynski Russ Binder Bill Turner Women's Athletic Association golf tennis Bill Forsyth cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The Ursinus Weekly, May 1, 1944
Senate proposes government plan with revised laws Whelan describes sinking of "Wasp" Characters selected for May Day pageant Junior Miss, former Broadway success, to be presented here May 19 and 20 Max Lerner to talk here...
Ursinus College Collegeville Pennsylvania newspaper student government May Day pageant George R. Whelan Henry K. Haines Max Lerner Janet Shoemaker Curtain Club Lantern Franklin I. Sheeder May H. Rauch Martha Franklin Roy F. Walz baseball English Club Dining Hall International Relations Club cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Emerging researcher pedagogies
This special edition of the Morning Watch is the second collection of papers from the Faculty of Education doctoral students who are participating in ED 702 A/B Advanced Research Methodology in Education in 2017/18. ED 702 is a...
Published by: The Morning Watch: Educational and Social Analysis
The Grizzly, January 27, 1989
Kevin Murphy, Michelle L. Grande, Todd Koser, Richard P. Richter, Coleen Casciano, Bob Gonnella, Matt Weintraub, Bridget Algeo, Lora L. Hart, Sharon Festa, Judd Woytek, Lenore Bailey, Gabriel Laboca, Steven Grim, Katherine Grim
Jan 01, 0001
Constructium Ursini Ad Hoc Hoists Honor New GPA: 2.25 or Dive! Letter: Green Shirt Makes Reed Red Fair Not Just for Freshmen Security Shacks in Reimert Beverly Oehlert Named to Pottstown Board of Directors Final Red and...
Ursinus College Collegeville Pennsylvania newspaper Wismer dining hall Jonny King Quintet Robin Greenstein campus security George Bush board of directors Llewellyn F. Dryfoos David J. Knauer field hockey Adele Boyd Swimming Basketball Beverly Oehlert Pottstown Memorial Medical Center Reimert Hall Red and Gold day activities fair grading system Olin Hall construction honor code cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
A Consensus on the Diagnosis and Treatment of Acromegaly Comorbidities
Andrea Giustina, Ariel Barkan, Albert Beckers, Nienke Biermasz, Beverly MK Biller, Cesar Boguszewski, Marek Bolanowski, Vivien Bonert, Marcello D Bronstein, Felipe F Casanueva, David Clemmons, Annamaria Colao, Diego Ferone, Maria Fleseriu, Stefano Frara, Monica R Gadelha, Ezio Ghigo, Mark Gurnell, Anthony P Heaney, Ken Ho, Adriana Ioachimescu, Laurence Katznelson, Fahrettin Kelestimur, John Kopchick, Michal Krsek, Steven Lamberts, Marco Losa, Anton Luger, Pietro Maffei, Monica Marazuela, Gherardo Mazziotti, Moises Mercado, Pietro Mortini, Sebastian Neggers, Alberto M Pereira, Stephan Petersenn, Manel Puig-Domingo, Roberto Salvatori, Ilan Shimon, Christian Strasburger, Stylianos Tsagarakis, AJ van der Lely, John Wass, Maria Chiara Zatelli, Shlomo Melmed
Dec 17, 2019
OBJECTIVE: The aim of the Acromegaly Consensus Group was to revise and update the consensus on diagnosis and treatment of acromegaly comorbidities last published in 2013. PARTICIPANTS: The Consensus Group, convened by 11...
The Ursinus Weekly, April 17, 1944
Curtain Club chooses comedy, Junior Miss for May production Juniors to present " A spring night" at annual prom this Friday evening Girls will present "The land of Oz" John McClellan named first vice-president for coming...
Ursinus College Collegeville Pennsylvania newspaper Curtain Club May Day pageant John McClellan Navy V-12 Marion G. Spangler United Nations Donald G. Baker debating club H. M. Leinbach Frank B. Reynolds Ray Cranston Music Club baseball softball Basketball William C. Hampton YMCA YWCA cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The Ursinus Weekly, November 6, 1944
Fleet men and Penn transfers comprise new group of seventy-five Navy trainees Old timers to return for reunion Saturday Student body is third largest in history with 107 freshmen Weekly ranks high in press rating Lecturer to...
Ursinus College Collegeville Pennsylvania newspaper Navy V-12 freshmen customs Old Timers Day Robert Heckert enrollment William Shafer National War Fund Sam Villanova YMCA YWCA student housing Patricia Middleton Alberto Flores alumni Perkiomen Creek Football field hockey Norman Thomas cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Improving Imaging Modalities in Early Psoriatic Arthritis
Tania Gudu, Beverly Ng, Hannah Jethwa, Catherine Graham, Veda Kudva, Jashmitha Rammanohar, Chen Zhang, Mark Sapsford, Deepak R Jadon
Jan 28, 2022
Objective: Despite recent advances, early diagnosis of psoriatic arthritis (PsA) remains a challenge in clinical practice. Ultrasound (US) could be a useful tool for the diagnosis and management of PsA. The objective of this...
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