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Pathogen selection drives nonoverlapping associations between HLA loci
Pathogen-mediated selection is commonly invoked as an explanation for the exceptional polymorphism of the HLA gene cluster, but its role in generating and maintaining linkage disequilibrium between HLA loci is unclear. Here we...
Pathogen selection drives nonoverlapping associations between HLA loci
Pathogen-mediated selection is commonly invoked as an explanation for the exceptional polymorphism of the HLA gene cluster, but its role in generating and maintaining linkage disequilibrium between HLA loci is unclear. Here we...
The erythrocyte membrane properties of beta thalassaemia heterozygotes and their consequences for Plasmodium falciparum invasion.
Viola Introini, Alejandro Marin-Menendez, Guilherme Nettesheim, Yen-Chun Lin, Silvia N Kariuki, Adrian L Smith, Letitia Jean, John N Brewin, David C Rees, Pietro Cicuta, Julian C Rayner, Bridget S Penman
Jun 29, 2022
Malaria parasites such as Plasmodium falciparum have exerted formidable selective pressures on the human genome. Of the human genetic variants associated with malaria protection, beta thalassaemia (a haemoglobinopathy) was the...
The erythrocyte membrane properties of beta thalassaemia heterozygotes and their consequences for Plasmodium falciparum invasion.
Charlotte Dance Festival Welcomes Winthrop Students' Original Choreography
Winthrop University
Jan 01, 0001
The four students are Mason Diaz, Kristin Ramirez, Kristin Ward and Bridget O'Connor. Their performance will be at 6 p.m. Sunday, March 22. The Charlotte Dance Festival will feature a few familiar faces this weekend.
Published by: Winthrop University
Fine Arts Students Take Home Photography Awards
Winthrop University
Jan 01, 0001
Junior fine arts major Rebecca Jacobs won second place in the undergraduate category, while art and design student Bridget Kirkland took second place in the graduate division. A total of nine students' work was accepted.
Published by: Winthrop University
Marine siliceous ecosystem decline led to sustained anomalous Early Triassic warmth.
Terry T Isson, Shuang Zhang, Kimberly V Lau, Sofia Rauzi, Nicholas J Tosca, Donald E Penman, Noah J Planavsky
Jun 18, 2022
In the wake of rapid CO2 release tied to the emplacement of the Siberian Traps, elevated temperatures were maintained for over five million years during the end-Permian biotic crisis. This protracted recovery defies our current...
Marine siliceous ecosystem decline led to sustained anomalous Early Triassic warmth.
Terry T Isson, Shuang Zhang, Kimberly V Lau, Sofia Rauzi, Nicholas J Tosca, Donald E Penman, Noah J Planavsky
Jul 19, 2022
In the wake of rapid CO2 release tied to the emplacement of the Siberian Traps, elevated temperatures were maintained for over five million years during the end-Permian biotic crisis. This protracted recovery defies our current...
The Grizzly, November 1, 2018
Courtney A DuChene, Madison Rodak, Skylar Haas, Kim Corona, Sophia DiBattista, Thomas Bantley, Shelsea Deravil, David Mendelsohn
Jan 01, 0001
Midterm Elections November 6 IDC Opening Honors Past President Fong, Celebrates Campus Milestone Deadline for "The Lantern" is Here Board of Trustees Comes to Campus Geology Professors go Under the IDC Meet the Charles Rice...
Ursinus College Collegeville Pennsylvania newspaper IDC Ryan Costello Lantern Board of Trustees Tristan Ashcroft Leah Joseph Doug Hickey Charles Rice Roseangela Hartford dress code Swimming Bridget Sherry field hockey cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The Grizzly, February 6, 2003
Anne Antanavage, '04, Kelly Gray, Quinn Dinsmore, Julia Campbell, Bart Brooks, Trevor Mohr, Fallon Szarko, Leslie Hoffman, Terri Wehnert, Lindsey Fund, Greg Pellish, Jerel Smith, Marie DiFeliciantonio
Jan 01, 0001
Fallen Heroes: Space Shuttle Columbia Disaster Best Buddies Goes "Under da Sea" A New Semester Means New Members for Ursinus Greeks The World Beyond Ursinus: Study Abroad Experience Plans in Progress: Contemporary Design...
Ursinus College Collegeville Pennsylvania newspaper Basketball Jen Nolan Bridget Hussey pledging Hoh Daiko drummers East Asian film J. D. Salinger study abroad Best Buddies cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Nursing in an age of multimorbidity.
BACKGROUND: A changing sociodemographic landscape has seen rising numbers of people with two or more long-term health conditions. Multimorbidity presents numerous challenges for patients and families and those who work in...
The effects of manipulating goal content and autonomy support climate on outcomes of a PE fitness class
Objectives: The present study tested the potential for manipulating adolescents' goals and motives for participation in a school physical education (PE) lesson, and explored the subsequent outcomes on participant experience....
Is mRNA decapping by ApaH like phosphatases present in eukaryotes beyond the Kinetoplastida?
BACKGROUND: ApaH like phosphatases (ALPHs) originate from the bacterial ApaH protein and have been identified in all eukaryotic super-groups. Only two of these proteins have been functionally characterised. We have shown that...
Multispecies reconstructions uncover widespread conservation, and lineage-specific elaborations in eukaryotic mRNA metabolism.
The degree of conservation and evolution of cytoplasmic mRNA metabolism pathways across the eukaryotes remains incompletely resolved. In this study, we describe a comprehensive genome and transcriptome-wide analysis of proteins...
The effects of manipulating goal content and autonomy support climate on outcomes of a PE fitness class
Objectives: The present study tested the potential for manipulating adolescents' goals and motives for participation in a school physical education (PE) lesson, and explored the subsequent outcomes on participant experience....
Synovium-Derived Mesenchymal Stem Cell Transplantation in Cartilage Regeneration
Articular cartilage damaged through trauma or disease has a limited ability to repair. Untreated, focal lesions progress to generalized changes including osteoarthritis. Musculoskeletal disorders including osteoarthritis are the...
Detection of neutralising antibodies to SARS-CoV-2 to determine population exposure in Scottish blood donors between March and May 2020.
Craig P Thompson, Nicholas E Grayson, Robert S Paton, Jai S Bolton, José Lourenço, Bridget S Penman, Lian N Lee, Valerie Odon, Juthathip Mongkolsapaya, Senthil Chinnakannan, Wanwisa Dejnirattisai, Matthew Edmans, Alex Fyfe, Carol Imlach, Kreepa Kooblall, Nicholas Lim, Chang Liu, César López-Camacho, Carol McInally, Anna L McNaughton, Narayan Ramamurthy, Jeremy Ratcliff, Piyada Supasa, Oliver Sampson, Beibei Wang, Alexander J Mentzer, Marc Turner, Malcolm G Semple, Kenneth Baillie, ISARIC4C investigators, Heli Harvala, Gavin R Screaton, Nigel Temperton, Paul Klenerman, Lisa M Jarvis, Sunetra Gupta, Peter Simmonds
Jan 18, 2021
BackgroundThe progression and geographical distribution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the United Kingdom (UK) and elsewhere is unknown because typically only symptomatic individuals...
Covid19 SARS-CoV-2 pandemic serology SURVEILLANCE Scotland Adult Antibodies Neutralizing Antibodies Viral Betacoronavirus Blood Donors covid-19 Cluster Analysis Coronavirus Infections Enzyme-Linked Immunosorbent Assay Female Geography Medical Humans Inhibitory Concentration 50 Male Models Immunological Neutralization Tests Pandemics Pneumonia Viral Population Surveillance prevalence SARS-CoV-2 Scotland Sensitivity and Specificity Seroepidemiologic Studies Urban Population
Mitochondrial Neurogastrointestinal Encephalomyopathy
Dario Pacitti, Michelle Levene, Caterina Garone, Niranjanan Nirmalananthan, Bridget E Bax
Apr 17, 2019
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an ultra-rare metabolic autosomal recessive disease, caused by mutations in the nuclear gene TYMP which encodes the enzyme thymidine phosphorylase. The resulting...
So very really variable
James Bulgin, Nicole Elford, Lindsay Harding, Bridget Henley, Suzanne Power, Crystal Walters
Nov 20, 2013
Previous studies have shown that one of the linguistic tools that individuals use to identify themselves is adjectival intensification (e.g., so cool, very cool, really cool). We assembled and analyzed a corpus of over 3000...
Published by: Atlantic Provinces Linguistic Association
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