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Results: 484
Variation in dermcidin expression in a range of primary human tumours and in hypoxic/oxidatively stressed human cell lines.
GD Stewart, RJE Skipworth, CJ Pennington, AG Lowrie, DAC Deans, DR Edwards, FK Habib, ACP Riddick, KCH Fearon, JA Ross
May 14, 2020
Dermcidin acts as a survival factor in a variety of cancer cell lines under hypoxia or oxidative stress. The aim of this study was to evaluate dermcidin expression in cell lines following simulation of tumour microenvironmental...
mRNA profiling of the cancer degradome in oesophago-gastric adenocarcinoma.
JP Baren, GD Stewart, A Stokes, K Gray, CJ Pennington, R O'Neill, DAC Deans, S Paterson-Brown, ACP Riddick, DR Edwards, KCH Fearon, JA Ross, RJE Skipworth
May 14, 2020
BACKGROUND: Degradation of the extracellular matrix is fundamental to tumour development, invasion and metastasis. Several protease families have been implicated in the development of a broad range of tumour types, including...
The Accuracy and Validity of the Simplified Pairs Method of Comparative Judgement in Highly Structured Papers
Comparative judgement (CJ) is often said to be more suitable for judging exam questions inviting extended responses, as it is easier for judges to make holistic judgements on a small number of large, extended tasks than...
Interactive effects of DRD2 rs6277 polymorphism, environment and sex on impulsivity in a population-representative study
Previous research has shown that dopaminergic dysregulation and early life stress interact to impact on aspects of impulse control. This study aimed to explore the potentially interactive effects of the rs6277 polymorphism of...
Beyond online participant crowdsourcing
Charlotte R. Pennington, Andrew J. Jones, Loukia Tzavella, Christopher D Chambers, Katherine S Button
Aug 31, 2022
Participant crowdsourcing platforms (e.g., MTurk, Prolific) offer numerous advantages to addiction science, permitting access to hard-to-reach populations and enhancing the feasibility of complex experimental, longitudinal...
What is the evidence that differences in ‘control over destiny’ lead to socioeconomic inequalities in health? A theory-led systematic review of high-quality longitudinal studies on pathways in the living environment
Lois Catherine Orton, Andy Pennington, Shilpa Nayak, Amanda Sowden, Mark Petticrew, Martin White, Margaret Whitehead
Jun 25, 2019
Exploring the Validity of Comparative Judgement
When completing a comparative judgment (CJ) exercise, judges are asked to make holistic decisions about the quality of the work they are comparing. A key consideration is the validity of expert judgements. This article...
CACNA1C methylation
Kyla Pennington, Kristel Klaus, Helene A Fachim, Kevin Butler, Ksenia Trischel, Caroline F Dalton, Adrian Heald, Gavin P Reynolds
Nov 10, 2020
Aim: We investigated morning cortisol, stress, rs1006737 and childhood trauma relationship with CACNA1C methylation. Materials & methods: Morning cortisol release, childhood trauma and perceived stress were collected and...
Beyond online participant crowdsourcing
Charlotte R. Pennington, Andrew J. Jones, Loukia Tzavella, Christopher D Chambers, Katherine S Button
Aug 31, 2022
Participant crowdsourcing platforms (e.g., MTurk, Prolific) offer numerous advantages to addiction science, permitting access to hard-to-reach populations and enhancing the feasibility of complex experimental, longitudinal...
Rise and Recharge
Abigail S Morris, Kelly A Mackintosh, David Dunstan, Neville Owen, Paddy Dempsey, Thomas Pennington, Melitta A McNarry
Dec 12, 2020
This feasibility study evaluated the effects of an individual-level intervention to target office workers total and prolonged sedentary behaviour during working hours, using an e-health smartphone application. A three-arm...
The Ursinus Weekly, May 23, 1927
"Jing" Johnson to hurl for alumni in annual tilt on Saturday, June 4 Little bears trounce Pennington Prep, 7-2 Tennis team wins five straight tilts, drops one to Moravian, Saturday Commencement week promises events of...
Ursinus College Collegeville Pennsylvania newspaper freshman customs Russell C. Johnson tennis Ted LaClair Theodore Heysham Men's Glee Club YMCA YWCA baseball cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Characterizing optimal sampling of binary contingency tables via the configuration model
A binary contingency table is an m × n array of binary entries with row sums r = (r1,..., rm) and column sums c = (c1,..., cn). The configuration model generates a contingency table by considering ri tokens of type 1 for each...
Characterizing optimal sampling of binary contingency tables via the configuration model
A binary contingency table is an m × n array of binary entries with row sums r = (r1,..., rm) and column sums c = (c1,..., cn). The configuration model generates a contingency table by considering ri tokens of type 1 for each...
CACNA1C methylation
Kyla Pennington, Kristel Klaus, Helene A Fachim, Kevin Butler, Ksenia Trischel, Caroline F Dalton, Adrian Heald, Gavin P Reynolds
Dec 10, 2020
Aim: We investigated morning cortisol, stress, rs1006737 and childhood trauma relationship with CACNA1C methylation. Materials & methods: Morning cortisol release, childhood trauma and perceived stress were collected and...
Cost-effectiveness of alternative minimum recall intervals between whole blood donations.
Zia Sadique, Sarah Willis, Kaat De Corte, Mark Pennington, Carmel Moore, Stephen Kaptoge, Emanuele Di Angelantonio, Gail Miflin, David J Roberts, Richard Grieve
Aug 17, 2022
BACKGROUND: The INTERVAL trial showed shorter inter-donation intervals could safely increase the frequency of whole-blood donation. We extended the INTERVAL trial to consider the relative cost-effectiveness of reduced...
The Ursinus Weekly, November 21, 1927
Many visitors expected to attend opening of new buildings on Tuesday Cast and technicians of Schaff play at work Fine talks given at H.-P. meeting Tuesday evening Will Durant main speaker at convention of voters Girls'...
Ursinus College Collegeville Pennsylvania newspaper Schaff literary society field hockey debate team Football YMCA YWCA cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The health impacts of women's low control in their living environment
Andy Pennington, Lois Orton, Shilpa Nayak, Adele Ring, Mark Petticrew, Amanda Sowden, Martin White, Margaret Whitehead
Jun 15, 2018
We conducted a systematic review of observational evidence on the health impacts of women's low control/autonomy in the living environment in societies with profound gender discrimination and gender bias. Thirty observational...
Adjusting for cross-cultural differences in computer-adaptive tests of quality of life.
PURPOSE: Previous studies using the WHOQOL measures have demonstrated that the relationship between individual items and the underlying quality of life (QoL) construct may differ between cultures. If unaccounted for, these...
Tetrahedral intrinsic structure of Oxygen-16 revisited
Abstract
A model for vibrational and rotational excitations of an intrinsic tetrahedral structure of the Oxygen-16 nucleus has been investigated, building on classic work of...
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