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EEG alpha reactivity and cholinergic system integrity in Lewy body dementia and Alzheimer's disease.
Julia Schumacher, Alan J Thomas, Luis R Peraza, Michael Firbank, Ruth Cromarty, Calum A Hamilton, Paul C Donaghy, John T O'Brien, John-Paul Taylor
May 24, 2020
BACKGROUND:Lewy body dementia (LBD), which includes dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD), is characterised by marked deficits within the cholinergic system which are more severe than in...
Nucleus basalis of Meynert Structural MRI dementia with Lewy bodies Resting state EEG Parkinson’s disease dementia
Published by: Alzheimer's research & therapy
EEG alpha reactivity and cholinergic system integrity in Lewy body dementia and Alzheimer’s disease
Julia Schumacher, Alan J. Thomas, Luis R. Peraza, Michael Firbank, Ruth Cromarty, Calum A. Hamilton, Paul C. Donaghy, John T. O’Brien, John-Paul Taylor
Jun 06, 2020
Abstract: Background: Lewy body dementia (LBD), which includes dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD), is characterised by marked deficits within the cholinergic system which are more severe than...
Quantitative EEG as a biomarker in mild cognitive impairment with Lewy bodies.
Julia Schumacher, John-Paul Taylor, Calum A Hamilton, Michael Firbank, Ruth A Cromarty, Paul C Donaghy, Gemma Roberts, Louise Allan, Jim Lloyd, Rory Durcan, Nicola Barnett, John T O'Brien, Alan J Thomas
Sep 21, 2020
OBJECTIVES: To investigate using quantitative EEG the (1) differences between patients with mild cognitive impairment with Lewy bodies (MCI-LB) and MCI with Alzheimer's disease (MCI-AD) and (2) its utility as a potential...
David Hume, Adam Smith, and William Hamilton of Bangour
Felix Waldmann
Jan 10, 2019
National Library of Scotland, MS 23159.7 is a thirty-two line poem in the hand of David Hume (1711–76), the philosopher. The poem is conserved within a collection of manuscripts devised to the Royal Society of Edinburgh in 1838...
The Ursinus Weekly, May 2, 1955
Richard Winchester, Eleanor R. McKelvie, Ray Hamilton, Spencer Foreman, Helen A. Stevenson, Hazel Okino, Dick Bowman, David Subin
Jan 01, 0001
Spring play May 12-14 in T-G gym "Y" installs officers at vespers Sunday Pre-meds to hear polio expert tonite Hamilton to head pre-legal society Meistersingers end season with "Music for you" National music frat installed...
Ursinus College Collegeville Pennsylvania newspaper Curtain Club YMCA YWCA Robert M. McAllister Brownback-Anders pre-medical society Ray Hamilton Pre-legal Society Meistersingers Pi Nu Epsilon May Day pageant Bulletin Sasha Siemal Ruby Louis Krug Collegeville-Trappe school district vandalism sororities fraternities track team Karl Herwig Lee Lawhead tennis Ted Sholl baseball Debating team Alpha Phi Omega Canterbury Club Franklin Watts cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Prospective predictors of decline v. stability in mild cognitive impairment with Lewy bodies or Alzheimer's disease.
Calum A Hamilton, Fiona E Matthews, Paul C Donaghy, John-Paul Taylor, John T O'Brien, Nicola Barnett, Kirsty Olsen, Ian G McKeith, Alan J Thomas
Apr 14, 2020
BACKGROUND: Mild cognitive impairment (MCI) may gradually worsen to dementia, but often remains stable for extended periods of time. Little is known about the predictors of decline to help explain this variation. We aimed to...
Alzheimer's Disease dementia with Lewy bodies latent class mixture modelling longitudinal decline mild cognitive impairment Aged Aged 80 and over Alzheimer Disease Cognitive Dysfunction Disease Progression England Female Humans latent class analysis Lewy Bodies Lewy Body Disease Longitudinal Studies Male Middle Aged Prospective Studies
EEG alpha reactivity and cholinergic system integrity in Lewy body dementia and Alzheimer's disease.
Julia Schumacher, Alan J Thomas, Luis R Peraza, Michael Firbank, Ruth Cromarty, Calum A Hamilton, Paul C Donaghy, John T O'Brien, John-Paul Taylor
Apr 07, 2020
BACKGROUND: Lewy body dementia (LBD), which includes dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD), is characterised by marked deficits within the cholinergic system which are more severe than in...
EEG alpha reactivity and cholinergic system integrity in Lewy body dementia and Alzheimer’s disease
Julia Schumacher, Alan J. Thomas, Luis R. Peraza, Michael Firbank, Ruth Cromarty, Calum A. Hamilton, Paul C. Donaghy, John T. O’Brien, John-Paul Taylor
Apr 22, 2021
Abstract: Background: Lewy body dementia (LBD), which includes dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD), is characterised by marked deficits within the cholinergic system which are more severe than...
Prospective longitudinal evaluation of cytokines in mild cognitive impairment due to AD and Lewy body disease.
Alan J Thomas, Calum A Hamilton, Paul C Donaghy, Carmen Martin-Ruiz, Chris M Morris, Nicola Barnett, Kirsty Olsen, John-Paul Taylor, John T O'Brien
Jun 18, 2020
OBJECTIVES: We conducted a prospective longitudinal study of plasma cytokines during the Mild Cognitive Impairment (MCI) stage of Lewy body disease and Alzheimer's disease, hypothesizing that cytokine levels would decrease over...
HBCU Technology Transfer Supply Chair Networks' Sustainability: Budget Resource Planning Tool Development
Clovia Hamilton
Jan 01, 0001
This study describes the development of a university technology transfer supply chain network sustainability tool that Historically Black Colleges and Universities (HBCUs) can use to become more self-reliant financially. HBCUs...
HBCU black colleges supply chain network technology transfer commercialization budget resource planning OPTIMIZATION Linear programming Business Administration, Management, and Operations Management Sciences and Quantitative Methods Operations and Supply Chain Management
Published by: Winthrop University
In vivo nucleus basalis of Meynert degeneration in mild cognitive impairment with Lewy bodies.
Julia Schumacher, John-Paul Taylor, Calum A Hamilton, Michael Firbank, Ruth A Cromarty, Paul C Donaghy, Gemma Roberts, Louise Allan, Jim Lloyd, Rory Durcan, Nicola Barnett, John T O'Brien, Alan J Thomas
May 10, 2021
OBJECTIVES: To investigate in vivo degeneration of the cholinergic system in mild cognitive impairment with Lewy bodies (MCI-LB), we studied nucleus basalis of Meynert (NBM) volumes from structural MR images and its relation to...
Cognitive Decline in Mild Cognitive Impairment With Lewy Bodies or Alzheimer Disease
Calum A Hamilton, Fiona E Matthews, Paul C Donaghy, John-Paul Taylor, John T O'Brien, Nicola Barnett, Kirsty Olsen, Jim Lloyd, George Petrides, Ian G McKeith, Alan J Thomas
Aug 07, 2020
OBJECTIVE: We explored whether the mild cognitive impairment (MCI) stages of dementia with Lewy bodies (DLB) and Alzheimer disease (AD) differ in their cognitive profiles, and longitudinal progression. DESIGN: A prospective...
Secular dynamics of binaries in stellar clusters - II. Dynamical evolution
Dense stellar clusters are natural sites for the origin and evolution of
exotic objects such as relativistic binaries (potential gravitational wave
sources), blue stragglers, etc. We investigate the secular dynamics of a...
Accuracy of dopaminergic imaging as a biomarker for mild cognitive impairment with Lewy bodies.
Gemma Roberts, Paul C Donaghy, Jim Lloyd, Rory Durcan, George Petrides, Sean J Colloby, Sarah Lawley, Joanna Ciafone, Calum A Hamilton, Michael Firbank, Louise Allan, Nicola Barnett, Sally Barker, Kirsty Olsen, Kim Howe, Tamir Ali, John-Paul Taylor, John O'Brien, Alan J Thomas
Nov 12, 2020
BACKGROUND: Dopaminergic imaging is an established biomarker for dementia with Lewy bodies, but its diagnostic accuracy at the mild cognitive impairment (MCI) stage remains uncertain. AIMS: To provide robust prospective evidence...
Mild cognitive impairment with Lewy bodies
Paul C Donaghy, Joanna Ciafone, Rory Durcan, Calum A Hamilton, Sally Barker, Jim Lloyd, Michael Firbank, Louise M Allan, John T O'Brien, John-Paul Taylor, Alan J Thomas
Aug 03, 2020
BACKGROUND: Recently published diagnostic criteria for mild cognitive impairment with Lewy bodies (MCI-LB) include five neuropsychiatric supportive features (non-visual hallucinations, systematised delusions, apathy, anxiety and...
Free water imaging of the cholinergic system in dementia with Lewy bodies and Alzheimer's disease.
Julia Schumacher, Nicola J Ray, Calum A Hamilton, Maurizio Bergamino, Paul C Donaghy, Michael Firbank, Rosie Watson, Gemma Roberts, Louise Allan, Nicola Barnett, John T O'Brien, Alan J Thomas, John-Paul Taylor
Mar 15, 2023
INTRODUCTION: Degeneration of cortical cholinergic projections from the nucleus basalis of Meynert (NBM) is characteristic of dementia with Lewy bodies (DLB) and Alzheimer's disease (AD), whereas involvement of cholinergic...
Slowing on quantitative EEG is associated with transition to dementia in mild cognitive impairment.
Calum A Hamilton, Julia Schumacher, Fiona Matthews, John-Paul Taylor, Louise Allan, Nicola Barnett, Ruth A Cromarty, Paul C Donaghy, Rory Durcan, Michael Firbank, Sarah Lawley, John T O'Brien, Gemma Roberts, Alan J Thomas
Aug 18, 2021
Electroencephalographic (EEG) abnormalities are greater in mild cognitive impairment (MCI) with Lewy bodies (MCI-LB) than in MCI due to Alzheimer's disease (MCI-AD) and may anticipate the onset of dementia. We aimed to assess...
Progression to Dementia in Mild Cognitive Impairment With Lewy Bodies or Alzheimer Disease.
Calum A Hamilton, Fiona E Matthews, Paul C Donaghy, John-Paul Taylor, John T O'Brien, Nicola Barnett, Kirsty Olsen, Rory Durcan, Gemma Roberts, Joanna Ciafone, Sally AH Barker, Michael Firbank, Ian G McKeith, Alan J Thomas
Mar 04, 2021
Dementia Alzheimer's Disease Related Dementias (ADRD) Acquired Cognitive Impairment Neurosciences Clinical Research Neurodegenerative Alzheimer's Disease Brain Disorders aging 4.1 Discovery and preclinical testing of markers and technologies 4 Detection screening and diagnosis 2.1 Biological and endogenous factors 2 Aetiology Neurological
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