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Brief Sensory Deprivation Triggers Cell Type-Specific Structural and Functional Plasticity in Olfactory Bulb Neurons.
Elisa Galliano, Christiane Hahn, Lorcan P Browne, Paula R Villamayor, Candida Tufo, Andres Crespo, Matthew S Grubb
Dec 03, 2020
Can alterations in experience trigger different plastic modifications in neuronal structure and function, and if so, how do they integrate at the cellular level? To address this question, we interrogated circuitry in the mouse...
Prevalence of Candida Non albicans Species Associated with Vulvovaginal Candidiasis in Egyptian Women
Mona M.A. Haleim1, Elham AM El-Feky1, Amal Sayed1, Dalia Kadry Ismail1, Ahmed Mahmoud Sayed2 and Rana MA Abdella2
May 11, 2015
Background: The prevalence of vulvovaginal candidiasis (VVC) caused by Candida non-albicans (CNA) species has increased dramatically in the recent decades. This study aimed to identify and to test antifungal susceptibility...
Published by: IJHS Medical Association
Comparative genome analysis and gene finding in Candida species using CGOB.
Sarah L Maguire, Seán S ÓhÉigeartaigh, Kevin P Byrne, Markus S Schröder, Peadar O'Gaora, Kenneth H Wolfe, Geraldine Butler
Aug 20, 2020
The Candida Gene Order Browser (CGOB) was developed as a tool to visualize and analyze synteny relationships in multiple Candida species, and to provide an accurate, manually curated set of orthologous Candida genes for...
Prevalence of Candida Non albicans Species Associated with Vulvovaginal Candidiasis in Egyptian Women
Mona M.A. Haleim1, Elham AM El-Feky1, Amal Sayed1, Dalia Kadry Ismail1, Ahmed Mahmoud Sayed2 and Rana MA Abdella2
May 11, 2015
Background: The prevalence of vulvovaginal candidiasis (VVC) caused by Candida non-albicans (CNA) species has increased dramatically in the recent decades. This study aimed to identify and to test antifungal susceptibility...
Published by: IJHS Medical Association
Detection of <em>Candida albicans</em> DNA from blood samples using a novel electrochemical assay
The genus Candida contains a number of yeast species which are opportunistic pathogens and are associated with life-threatening infections in immunocompromised individuals. Provision of appropriate therapy relies on the rapid...
Detection of <em>Candida albicans</em> DNA from blood samples using a novel electrochemical assay
The genus Candida contains a number of yeast species which are opportunistic pathogens and are associated with life-threatening infections in immunocompromised individuals. Provision of appropriate therapy relies on the rapid...
Global analysis of the evolution and mechanism of echinocandin resistance in <em>Candida glabrata</em>
S.D. Singh-Babak, T. Babak, S. Diezmann, J. A. Hill, J. L. Xie, Y.-L. Chen, S. M. Poutanen, R. P. Rennie, J. Heitman, L. E. Cowen
May 01, 2012
The evolution of drug resistance has a profound impact on human health. Candida glabrata is a leading human fungal pathogen that can rapidly evolve resistance to echinocandins, which target cell wall biosynthesis and are...
Global analysis of the evolution and mechanism of echinocandin resistance in <em>Candida glabrata</em>
S.D. Singh-Babak, T. Babak, S. Diezmann, J. A. Hill, J. L. Xie, Y.-L. Chen, S. M. Poutanen, R. P. Rennie, J. Heitman, L. E. Cowen
May 01, 2012
The evolution of drug resistance has a profound impact on human health. Candida glabrata is a leading human fungal pathogen that can rapidly evolve resistance to echinocandins, which target cell wall biosynthesis and are...
In Candida albicans, the Nim1 kinases Gin4 and Hsl1 negatively regulate pseudohypha formation and Gin4 also controls septin organization.
In the development of hyphal germ tubes of Candida albicans, a band of septin forms at the base of the germ tube (basal septin band). Later, a septin ring forms, which organizes the first septum within the germ tube (septin...
Candida albicans Cell Cycle Proteins Cell Division Cyclin-Dependent Kinases Cytoskeletal Proteins Fungal Proteins GTP Phosphohydrolases Humans Hyphae Phenotype Protein Serine-Threonine Kinases Protein-Tyrosine Kinases Recombinant Fusion Proteins Saccharomyces cerevisiae Proteins Schizosaccharomyces pombe Proteins
Mapping the Hsp90 genetic interaction network in <em>Candida albicans</em> reveals environmental contingency and rewired circuitry
The molecular chaperone Hsp90 regulates the folding of diverse signal transducers in all eukaryotes, profoundly affecting cellular circuitry. In fungi, Hsp90 influences development, drug resistance, and evolution. Hsp90...
Mapping the Hsp90 genetic interaction network in <em>Candida albicans</em> reveals environmental contingency and rewired circuitry
The molecular chaperone Hsp90 regulates the folding of diverse signal transducers in all eukaryotes, profoundly affecting cellular circuitry. In fungi, Hsp90 influences development, drug resistance, and evolution. Hsp90...
An Erg11 lanosterol 14-α-demethylase-Arv1 complex is required for Candida albicans virulence
Michelle L. Villasmil, Antonio Daniel Barbosa, Jessie Lee Cunningham, Symeon Siniossoglou, Joseph T. Nickels
Jul 17, 2020
Azole resistant fungal infections remain a health problem for the immune compromised. Current therapies are limited due to rises in new resistance mechanisms. Therefore, it is important to identify new drug targets for drug...
An Erg11 lanosterol 14-α-demethylase-Arv1 complex is required for Candida albicans virulence.
Michelle L Villasmil, Antonio Daniel Barbosa, Jessie Lee Cunningham, Symeon Siniossoglou, Joseph T Nickels
Sep 15, 2020
Azole resistant fungal infections remain a health problem for the immune compromised. Current therapies are limited due to rises in new resistance mechanisms. Therefore, it is important to identify new drug targets for drug...
Amino Acid Sequence Animals Antifungal Agents Candida albicans Candidiasis Cytochrome P-450 Enzyme System Drug Resistance Fungal Fungal Proteins Male Membrane Proteins Mice Mice Inbred BALB C Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins Sequence Homology Sterol 14-Demethylase Virulence
Molecular phylogeny of sequenced <i>Saccharomycetes</i> reveals polyphyly of the alternative yeast codon usage
The universal genetic code defines the translation of nucleotide triplets, called codons, into amino acids. In many Saccharomycetes a unique alteration of this code affects the translation of the CUG codon, which is normally...
Molecular phylogeny of sequenced <i>Saccharomycetes</i> reveals polyphyly of the alternative yeast codon usage
The universal genetic code defines the translation of nucleotide triplets, called codons, into amino acids. In many Saccharomycetes a unique alteration of this code affects the translation of the CUG codon, which is normally...
Tolerance of pentose utilising yeast to hydrogen peroxide-induced oxidative stress.
BACKGROUND: Bioethanol fermentations follow traditional beverage fermentations where the yeast is exposed to adverse conditions such as oxidative stress. Lignocellulosic bioethanol fermentations involve the conversion of pentose...
Bodily changes and sensory sensitivity in complex regional pain syndrome and fibromyalgia
Antonia F Ten Brink, Louisa Peters, Paraskevi-Ioanna Kompouli, Abbie Jordan, Candida S McCabe, Andreas Goebel, Janet H Bultitude
Jun 01, 2020
Complex regional pain syndrome (CRPS) and fibromyalgia are chronic pain conditions of unexplained origins. In addition to symptoms in the diagnostic criteria, patients can report changes to vision and other sensations or...
Bodily changes and sensory sensitivity in complex regional pain syndrome and fibromyalgia
Antonia F Ten Brink, Louisa Peters, Paraskevi-Ioanna Kompouli, Abbie Jordan, Candida S McCabe, Andreas Goebel, Janet H Bultitude
Jun 01, 2020
Complex regional pain syndrome (CRPS) and fibromyalgia are chronic pain conditions of unexplained origins. In addition to symptoms in the diagnostic criteria, patients can report changes to vision and other sensations or...
A CRISPR/Cas9-Based Mutagenesis Protocol for Brachypodium distachyon and Its Allopolyploid Relative, Brachypodium hybridum.
Karolina Hus, Alexander Betekhtin, Artur Pinski, Magdalena Rojek-Jelonek, Ewa Grzebelus, Candida Nibau, Mingjun Gao, Katja E Jaeger, Glyn Jenkins, John H Doonan, Robert Hasterok
Jun 03, 2020
The CRISPR/Cas9 system enables precise genome editing and is a useful tool for functional genomic studies. Here we report a detailed protocol for targeted genome editing in the model grass Brachypodium distachyon and its...
Structure of crystalline and amorphous materials in the NASICON system Na<sub>1+x</sub>Al<sub>x</sub>Ge<sub>2- x</sub>(PO<sub>4</sub>)<sub>3</sub>
Lawrence V.D. Gammond, Henry Auer, Rita Mendes Da Silva, Anita Zeidler, Jairo F. Ortiz-Mosquera, Adriana M. Nieto-Muñoz, Ana Candida M. Rodrigues, Igor D'Anciães Almeida Silva, Hellmut Eckert, Chris J. Benmore, Philip S. Salmon
Aug 21, 2021
The structure of crystalline and amorphous materials in the sodium (Na) super-ionic conductor system Na1+xAlxGe2-x(PO4)3 with x = 0, 0.4, and 0.8 was investigated by combining (i) neutron and x-ray powder diffraction and...
Structure of crystalline and amorphous materials in the NASICON system Na<sub>1+x</sub>Al<sub>x</sub>Ge<sub>2- x</sub>(PO<sub>4</sub>)<sub>3</sub>
Lawrence V.D. Gammond, Henry Auer, Rita Mendes Da Silva, Anita Zeidler, Jairo F. Ortiz-Mosquera, Adriana M. Nieto-Muñoz, Ana Candida M. Rodrigues, Igor D'Anciães Almeida Silva, Hellmut Eckert, Chris J. Benmore, Philip S. Salmon
Aug 21, 2021
The structure of crystalline and amorphous materials in the sodium (Na) super-ionic conductor system Na1+xAlxGe2-x(PO4)3 with x = 0, 0.4, and 0.8 was investigated by combining (i) neutron and x-ray powder diffraction and...
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