BACKGROUND: Discontinuation of metformin therapy, if started beyond menarche in adolescents or young women with hyperinsulinaemia following low birthweight, is rapidly followed by rebound deteriorations in body fat, insulin...
In his epistle Les "Vous" et les "Tu", Voltaire calls his sweetheart "tu" and"valls" alternately. He could use the familiar address when she was youngand unambitious, but now that she has become a rich and distant lady...
In his epistle Les "Vous" et les "Tu", Voltaire calls his sweetheart "tu" and"valls" alternately. He could use the familiar address when she was youngand unambitious, but now that she has become a rich and distant lady...
PURPOSE: The translation of genome sequencing into routine health care has been slow, partly because of concerns about affordability. The aspirational cost of sequencing a genome is $1000, but there is little evidence to support...
BACKGROUND: In mammalians, HIF is a master regulator of hypoxia gene expression through direct binding to DNA, while its role in microRNA expression regulation, critical in the hypoxia response, is not elucidated genome wide....
The primary aim of the Obemat2.0 trial was to evaluate the efficacy of a multicomponent motivational program for the treatment of childhood obesity, coordinated between primary care and hospital specialized services, compared to...
Recent studies have provided evidence for rapid pathogen genome diversification, some of which could potentially affect the course of disease. We have previously described such variation seen between isolates infecting the blood...
Abstract: Purpose: The translation of genome sequencing into routine health care has been slow, partly because of concerns about affordability. The aspirational cost of sequencing a genome is $1000, but there is little evidence...
BACKGROUND & AIMS: The aim was to generate a predictive equation to assess body composition (BC) in children with obesity using bioimpedance (BIA), and avoid bias produced by different density levels of fat free mass (FFM) in...
Education has been related to various advantageous lifetime outcomes. Here, using longitudinal structural MRI data (4,422 observations), we tested the influential hypothesis that higher education translates into slower rates of...
Streptococcus pneumoniae is a common nasopharyngeal colonizer, but can also cause life-threatening invasive diseases such as empyema, bacteremia and meningitis. Genetic variation of host and pathogen is known to play a role in...
The Global Alliance for Genomics and Health (GA4GH) aims to accelerate biomedical advances by enabling the responsible sharing of clinical and genomic data through both harmonized data aggregation and federated approaches. The...
The first full angular analysis of the $B^0 \to D^{*-} D_s^{*+}$ decay is
performed using 6 fb$^{-1}$ of $pp$ collision data collected with the LHCb
experiment at a centre-of-mass energy of 13 TeV. The $D_s^{*+} \to...
Searches for $CP$ violation in the two-body decays $D_{(s)}^{+}\rightarrow
h^{+}\pi^{0}$ and $D_{(s)}^{+} \rightarrow h^{+}\eta$ (where $h^{+}$ denotes a
$\pi^{+}$ or $K^{+}$ meson) are performed using $pp$ collision data...
Abstract: A branching fraction measurement of the B0→Ds+π- decay is presented using proton–proton collision data collected with the LHCb experiment, corresponding to an integrated luminosity of 5.0fb-1. The branching fraction is...
Abstract: Long-lived particles decaying to e±μ∓ν, with masses between 7 and 50GeV/c2 and lifetimes between 2 and 50ps, are searched for by looking at displaced vertices containing electrons and muons of opposite charges. The...
A measurement of $CP$-violating observables is performed using the decays
$B^\pm\to D K^\pm$ and $B^\pm\to D \pi^\pm$, where the $D$ meson is
reconstructed in one of the self-conjugate three-body final states...
A search is performed for massive long-lived particles (LLP) decaying
semileptonically into a muon and two quarks. Two kinds of LLP production
processes were considered. In the first, a Higgs-like boson with mass from 30
to 200...
Abstract: A structure is observed in the B±K∓ mass spectrum in a sample of proton–proton collisions at centre-of-mass energies of 7, 8, and 13 TeV, collected with the LHCb detector and corresponding to a total integrated...
Abstract: An angular analysis of the B0 → K*0e+e− decay is performed using a data sample corresponding to an integrated luminosity of 9 fb−1 of pp collisions collected with the LHCb experiment. The analysis is conducted in the...