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Dendritic Cells Initiate Immune Control of Epstein-Barr Virus Transformation of B Lymphocytes in Vitro
The initiation of cell-mediated immunity to Epstein-Barr virus (EBV) has been analyzed with cells from EBV-seronegative blood donors in culture. The addition of dendritic cells (DCs) is essential to prime naive T cells that...
Published by: Rockefeller University
An efficient arabinoxylan-debranching α-L-arabinofuranosidase of family GH62 from Aspergillus nidulans contains a secondary carbohydrate binding site.
Casper Wilkens, Susan Andersen, Bent O Petersen, An Li, Marta Busse-Wicher, Johnny Birch, Darrell Cockburn, Hiroyuki Nakai, Hans EM Christensen, Birthe B Kragelund, Paul Dupree, Barry McCleary, Ole Hindsgaul, Maher Abou Hachem, Birte Svensson
Mar 21, 2016
Affinity gel electrophoresis Arabinoxylan Arabinoxylooligosaccharides Glycoside hydrolase family 62 Inverting mechanism Surface binding site Arabinose Aspergillus nidulans Binding Sites Catalytic Domain Cloning Molecular Fungal Proteins Gene Expression Regulation Fungal Glycoside Hydrolases Phylogeny Pichia Polysaccharides Protein Conformation Streptomyces Substrate Specificity Triticum Xylans Xylose beta-Glucans
Wnt Gene Expression During Early Embryogenesis in the Nymphalid Butterfly Bicyclus anynana
Wnt signaling pathways are involved in many important cellular processes including proliferation and differentiation. Wnt ligands are released by source cells and signal to target cells by binding to the Frizzled receptor family...
A novel framework for inferring parameters of transmission from viral sequence data.
Transmission between hosts is a critical part of the viral lifecycle. Recent studies of viral transmission have used genome sequence data to evaluate the number of particles transmitted between hosts, and the role of selection...
Adaptation in Work and Family Roles Link Support to Mental Health During a Pandemic
We address a key unresolved issue in the social support literature—how social support relates to psychological health—by examining behavioural adaptation as a mechanism through which support from work and family domains...
Adaptation Work and family social support Mental Health pandemic Covid 19 /dk/atira/pure/subjectarea/asjc/3200/3202 name=Applied Psychology /dk/atira/pure/subjectarea/asjc/1400/1407 name=Organizational Behavior and Human Resource Management /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being /dk/atira/pure/sustainabledevelopmentgoals/decent_work_and_economic_growth name=SDG 8 - Decent Work and Economic Growth
A large effective population size for established within-host influenza virus infection.
effective population size evolutionary biology Genetic Drift infectious disease microbiology selection Virus within-host evolution Child Preschool Genetic Drift Genome Viral Humans Immunocompromised Host Infant Influenza B virus Influenza Human Population Density selection Genetic Stochastic Processes whole genome sequencing
Inferring Transmission Bottleneck Size from Viral Sequence Data Using a Novel Haplotype Reconstruction Method.
Simulation of primary particle size distributions in a premixed ethylene stagnation flame
Dingyu Hou, Casper S Lindberg, Mengda Wang, Manoel Y Manuputty, Xiaoqing You, Markus Kraft
Mar 19, 2020
Numerical simulation of soot formation in a laminar premixed burner-stabilized ethylene stagnation flame was performed with a detailed population balance model (DPBM) capable of tracking full structural details of aggregates as...
Compulsive sexual behavior
Casper Schmidt, Laurel S Morris, Timo L Kvamme, Paula Hall, Thaddeus Birchard, Valerie Voon
Dec 13, 2016
BACKGROUND: Compulsive sexual behaviors (CSB) are relatively common and associated with significant personal and social dysfunction. The underlying neurobiology is still poorly understood. The present study examines brain...
A bias towards natural rewards away from gambling cues in gamblers undergoing active treatment.
Casper Schmidt, Carsten Gleesborg, Hema Schmidt, Timo L Kvamme, Torben E Lund, Valerie Voon, Arne Møller
Apr 20, 2021
BACKGROUND: Disorders of substance and behavioral addiction are believed to be associated with a myopic bias towards the incentive salience of addiction-related cues away from general rewards in the environment. In non-treatment...
gambling disorder MID task orbitofrontal cortex Reward dissociation Striatum fMRI Adult Anticipation Psychological Brain Mapping Cognitive Behavioral Therapy Cues dorsolateral prefrontal cortex echo-planar imaging Erotica Female Gambling Gyrus Cinguli Humans Male motivation Reward Treatment Outcome Ventral Striatum Young Adult
Mapping gene by early life stress interactions on child subcortical brain structures
Koen Bolhuis, Rosa H Mulder, Casper Louk de Mol, Serena Defina, Varun Warrier, Tonya White, Henning Tiemeier, Ryan L Muetzel, Charlotte AM Cecil
Nov 17, 2022
BACKGROUND: Although it is well-established that both genetics and the environment influence brain development, they are typically examined separately. Here, we aimed to prospectively investigate the interactive effects of...
Adaptation in Work and Family Roles Link Support to Mental Health During a Pandemic
We address a key unresolved issue in the social support literature—how social support relates to psychological health—by examining behavioural adaptation as a mechanism through which support from work and family domains...
Adaptation Work and family social support Mental Health pandemic Covid 19 /dk/atira/pure/subjectarea/asjc/3200/3202 name=Applied Psychology /dk/atira/pure/subjectarea/asjc/1400/1407 name=Organizational Behavior and Human Resource Management /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being /dk/atira/pure/sustainabledevelopmentgoals/decent_work_and_economic_growth name=SDG 8 - Decent Work and Economic Growth
Reference values for intracranial pressure and lumbar cerebrospinal fluid pressure
Nicolas Hernandez Norager, Markus Harboe Olsen, Sarah Hornshoej Pedersen, Casper Schwartz Riedel, Marek Czosnyka, Marianne Juhler
Apr 13, 2021
Sexually dimorphic brain volume interaction in college-aged binge drinkers.
Timo L Kvamme, Casper Schmidt, Daniela Strelchuk, Yee Chien Chang-Webb, Kwangyeol Baek, Valerie Voon
Dec 18, 2015
Fcα Receptor-1-Activated Monocytes Promote B Lymphocyte Migration and IgA Isotype Switching.
Amélie V Bos, Melissa MJ van Gool, Annelot C Breedveld, Richard van der Mast, Casper Marsman, Gerd Bouma, Mark A van de Wiel, S Marieke van Ham, Reina E Mebius, Marjolein van Egmond
Oct 06, 2022
Fcα Receptor-1-Activated Monocytes Promote B Lymphocyte Migration and IgA Isotype Switching.
Amélie V Bos, Melissa MJ van Gool, Annelot C Breedveld, Richard van der Mast, Casper Marsman, Gerd Bouma, Mark A van de Wiel, S Marieke van Ham, Reina E Mebius, Marjolein van Egmond
Nov 16, 2022
Patients with inflammatory bowel disease (IBD) produce enhanced immunoglobulin A (IgA) against the microbiota compared to healthy individuals, which has been correlated with disease severity. Since IgA complexes can potently...
Mapping gene by early life stress interactions on child subcortical brain structures
Koen Bolhuis, Rosa H Mulder, Casper Louk de Mol, Serena Defina, Varun Warrier, Tonya White, Henning Tiemeier, Ryan L Muetzel, Charlotte A M Cecil
Mar 16, 2023
Background
Although it is well-established that both genetics and the environment influence brain development, they are typically examined separately. Here, we aimed to prospectively investigate the interactive effects...
Published by: JCPP advances
Exclusion of integrins from CNS axons is regulated by Arf6 activation and the AIS.
Elske HP Franssen, Rong-Rong Zhao, Hiroaki Koseki, Venkateswarlu Kanamarlapudi, Casper C Hoogenraad, Richard Eva, James W Fawcett
May 21, 2015
Motion estimation and correction for simultaneous PET/MR using SIRF and CIL
Richard Brown, Christoph Kolbitsch, Claire Delplancke, Evangelos Papoutsellis, Johannes Mayer, Evgueni Ovtchinnikov, Edoardo Pasca, Radhouene Neji, Casper da Costa-Luis, Ashley G Gillman, Matthias J Ehrhardt, Jamie R McClelland, Bjoern Eiben, Kris Thielemans
Aug 23, 2021
SIRF is a powerful PET/MR image reconstruction research tool for processing data and developing new algorithms. In this research, new developments to SIRF are presented, with focus on motion estimation and correction. SIRF's...
SIRF
Evgueni Ovtchinnikov, Richard Brown, Christoph Kolbitsch, Edoardo Pasca, Casper da Costa-Luis, Ashley G. Gillman, Benjamin A. Thomas, Nikos Efthimiou, Johannes Mayer, Palak Wadhwa, Matthias J. Ehrhardt, Sam Ellis, Jakob S. Jørgensen, Julian Matthews, Claudia Prieto, Andrew J. Reader, Charalampos Tsoumpas, Martin Turner, David Atkinson, Kris Thielemans
Apr 30, 2020
The combination of positron emission tomography (PET) with magnetic resonance (MR) imaging opens the way to more accurate diagnosis and improved patient management. At present, the data acquired by PET-MR scanners are...
Motion estimation and correction for simultaneous PET/MR using SIRF and CIL
Richard Brown, Christoph Kolbitsch, Claire Delplancke, Evangelos Papoutsellis, Johannes Mayer, Evgueni Ovtchinnikov, Edoardo Pasca, Radhouene Neji, Casper da Costa-Luis, Ashley G Gillman, Matthias J Ehrhardt, Jamie R McClelland, Bjoern Eiben, Kris Thielemans
Aug 23, 2021
SIRF is a powerful PET/MR image reconstruction research tool for processing data and developing new algorithms. In this research, new developments to SIRF are presented, with focus on motion estimation and correction. SIRF's...
Macroevolutionary shifts of WntA function potentiate butterfly wing-pattern diversity.
Anyi Mazo-Vargas, Carolina Concha, Luca Livraghi, Darli Massardo, Richard WR Wallbank, Linlin Zhang, Joseph D Papador, Daniel Martinez-Najera, Chris D Jiggins, Marcus R Kronforst, Casper J Breuker, Robert D Reed, Nipam H Patel, W Owen McMillan, Arnaud Martin
Jan 17, 2018
Butterfly wing patterns provide a rich comparative framework to study how morphological complexity develops and evolves. Here we used CRISPR/Cas9 somatic mutagenesis to test a patterning role for WntA, a signaling ligand gene...
Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive multiple sclerosis (MS-STAT)
Jeremy Chataway, Nadine Schuerer, Ali Alsanousi, Dennis Chan, David MacManus, Kelvin Hunter, Val Anderson, Charles RM Bangham, Shona Clegg, Casper Nielsen, Nick C Fox, David Wilkie, Jennifer M Nicholas, Virginia L Calder, John Greenwood, Chris Frost, Richard Nicholas
Oct 10, 2018
BACKGROUND: Secondary progressive multiple sclerosis, for which no satisfactory treatment presently exists, accounts for most of the disability in patients with multiple sclerosis. Simvastatin, which is widely used for treatment...
SIRF
Evgueni Ovtchinnikov, Richard Brown, Christoph Kolbitsch, Edoardo Pasca, Casper da Costa-Luis, Ashley G. Gillman, Benjamin A. Thomas, Nikos Efthimiou, Johannes Mayer, Palak Wadhwa, Matthias J. Ehrhardt, Sam Ellis, Jakob S. Jørgensen, Julian Matthews, Claudia Prieto, Andrew J. Reader, Charalampos Tsoumpas, Martin Turner, David Atkinson, Kris Thielemans
Apr 30, 2020
The combination of positron emission tomography (PET) with magnetic resonance (MR) imaging opens the way to more accurate diagnosis and improved patient management. At present, the data acquired by PET-MR scanners are...
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