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An energy and carbon life cycle assessment of tidal power case study
Under the Kyoto Protocol many countries have targets to reduce carbon emissions and increase renewable energy production. In order to do this effectively the impact and efficacy of differing schemes must be determined. One...
An energy and carbon life cycle assessment of tidal power case study
Under the Kyoto Protocol many countries have targets to reduce carbon emissions and increase renewable energy production. In order to do this effectively the impact and efficacy of differing schemes must be determined. One...
Receptor Activity-modifying Protein-directed G Protein Signaling Specificity for the Calcitonin Gene-related Peptide Family of Receptors.
Cathryn Weston, Ian Winfield, Matthew Harris, Rose Hodgson, Archna Shah, Simon J Dowell, Juan Carlos Mobarec, David A Woodlock, Christopher A Reynolds, David R Poyner, Harriet A Watkins, Graham Ladds
Oct 21, 2016
CGRP G protein-coupled receptor (GPCR) RAMP adrenomedullin adrenomedullin 2 Molecular dynamics molecular modeling signal bias Signal Transduction Yeast Adrenomedullin Cyclic AMP GTP-Binding Protein alpha Subunits HEK293 Cells Humans Nuclear Proteins Receptors Calcitonin Gene-Related Peptide Second Messenger Systems
Modulation of Glucagon Receptor Pharmacology by Receptor Activity-modifying Protein-2 (RAMP2).
Cathryn Weston, Jing Lu, Naichang Li, Kerry Barkan, Gareth O Richards, David J Roberts, Timothy M Skerry, David Poyner, Meenakshi Pardamwar, Christopher A Reynolds, Simon J Dowell, Gary B Willars, Graham Ladds
Jul 24, 2015
New method for tracking the movement of ionospheric plasma
A method to track the flow of plasma in the Earth's ionosphere is presented. This takes maps of total electron content (TEC) at various times, and by comparing them derives a map of bulk velocities. The method is a modification...
A comparison of the relative effect of the Earth’s Quasi-D.C. and A.C. electric field on Gradient Drift Waves in large-scale plasma structures in the polar regions
Radio signals traversing polar-cap plasma patches and other large-scale plasma structures in polar regions are prone to scintillation. This implies that irregularities in electron concentration often form within such structures....
Isolating the multipath component in GNSS signal-to-noise data and locating reflecting objects
A filter to separate the effect of multipath in Global Navigation Satellite System (GNSS) signal-to-noise ratio (SNR) data is presented. The filter removes multipath cleanly, and affects neither slowly varying trends (such as...
Polar-cap plasma patch primary linear instability growth-rates compared
Four primary plasma instability processes have been proposed in the literature to explain the generation of phase scintillation associated with polar-cap plasma patches. These are the Gradient Drift, Current Convective and...
Tomographic Imaging of Traveling Ionospheric Disturbances Using GNSS and Geostationary Satellite Observations
Abstract Traveling ionospheric disturbances (TIDs) are the manifestations of atmospheric gravity waves in the ionosphere. These disturbances have practical importance because they affect satellite navigation technologies such as...
Imaging of 3-D plasmaspheric electron density using GPS to LEO satellite differential phase observations
This paper outlines a new mathematical approach to imaging the electron density distribution in the high regions of the topside ionosphere and the plasmasphere from 800 km up to 20,200 km altitude using GPS measurements from low...
New method for tracking the movement of ionospheric plasma
A method to track the flow of plasma in the Earth's ionosphere is presented. This takes maps of total electron content (TEC) at various times, and by comparing them derives a map of bulk velocities. The method is a modification...
Reduction in the ionospheric error for a single-frequency GPS timing solution using tomography
Single-frequency Global Positioning System (GPS) receivers do not accurately compensate for the ionospheric delay imposed upon a GPS signal. They rely upon models to compensate for the ionosphere. This delay compensation can be...
Polar-cap plasma patch primary linear instability growth-rates compared
Four primary plasma instability processes have been proposed in the literature to explain the generation of phase scintillation associated with polar-cap plasma patches. These are the Gradient Drift, Current Convective and...
Tomographic Imaging of Traveling Ionospheric Disturbances Using GNSS and Geostationary Satellite Observations
Abstract Traveling ionospheric disturbances (TIDs) are the manifestations of atmospheric gravity waves in the ionosphere. These disturbances have practical importance because they affect satellite navigation technologies such as...
Isolating the multipath component in GNSS signal-to-noise data and locating reflecting objects
A filter to separate the effect of multipath in Global Navigation Satellite System (GNSS) signal-to-noise ratio (SNR) data is presented. The filter removes multipath cleanly, and affects neither slowly varying trends (such as...
A comparison of the relative effect of the Earth’s Quasi-D.C. and A.C. electric field on Gradient Drift Waves in large-scale plasma structures in the polar regions
Radio signals traversing polar-cap plasma patches and other large-scale plasma structures in polar regions are prone to scintillation. This implies that irregularities in electron concentration often form within such structures....
Four-dimensional electrical capacitance tomography imaging using experimental data
Electrical capacitance tomography (ECT) is a relatively mature non-invasive imaging technique that attempts to map dielectric permittivity of materials. ECT has become a promising monitoring technique in industrial process...
GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation.
Makoto Shigeto, Reshma Ramracheya, Andrei I Tarasov, Chae Young Cha, Margarita V Chibalina, Benoit Hastoy, Koenraad Philippaert, Thomas Reinbothe, Nils Rorsman, Albert Salehi, William R Sones, Elisa Vergari, Cathryn Weston, Julia Gorelik, Masashi Katsura, Viacheslav O Nikolaev, Rudi Vennekens, Manuela Zaccolo, Antony Galione, Paul RV Johnson, Kohei Kaku, Graham Ladds, Patrik Rorsman
Nov 19, 2015
A 12 year comparison of MIDAS and IRI 2007 ionospheric Total Electron Content
Data assimilation in conventional meteorological applications uses measurements in conjunction with a physical model. In the case of the ionised region of the upper atmosphere, the ionosphere, assimilation techniques are much...
Rapid and Accurate Measurement of Polarization and Fading of Weak VHF Signals Obliquely Reflected from Sporadic-E Layers
In the E-region of the ionosphere, at heights between 90 and 130 km, thin patches of enhanced ionization occur intermittently. The electron density in these sporadic-E (Es) clouds can sometimes be so high that radio waves...
Genetics of stroke in a UK African ancestry case-control study
Matthew Traylor, Loes Rutten-Jacobs, Charles Curtis, Hamel Patel, Gerome Breen, Stephen Newhouse, Cathryn M Lewis, Hugh S Markus
Nov 20, 2018
OBJECTIVE: Despite epidemiologic data showing an increased stroke incidence in African ancestry populations, genetic studies in this group have so far been limited, and there has been little characterization of the genetic...
Pharmacogenetic testing through the direct-to-consumer genetic testing company 23andMe.
BACKGROUND: Rapid advances in scientific research have led to an increase in public awareness of genetic testing and pharmacogenetics. Direct-to-consumer (DTC) genetic testing companies, such as 23andMe, allow consumers to...
Imaging of 3-D plasmaspheric electron density using GPS to LEO satellite differential phase observations
This paper outlines a new mathematical approach to imaging the electron density distribution in the high regions of the topside ionosphere and the plasmasphere from 800 km up to 20,200 km altitude using GPS measurements from low...
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