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Results: 25
Teenagers want to be told when a parent's death is near
Tove Bylund-Grenklo, Ulrika Kreicbergs, Charlotta Uggla, Unnur A Valdimarsdóttir, Tommy Nyberg, Gunnar Steineck, Carl Johan Fürst
Jun 21, 2018
BACKGROUND: We aimed to investigate cancer-bereaved youths' opinions and experiences of being told about a parent's imminent death from cancer and of barriers to this communication. MATERIAL AND METHODS: This nationwide...
Reprogramming Human Adult Fibroblasts into GABAergic Interneurons.
Andreas Bruzelius, Srisaiyini Kidnapillai, Janelle Drouin-Ouellet, Tom Stoker, Roger Barker, Daniella Rylander Ottosson
Jan 04, 2022
Direct reprogramming is an appealing strategy to generate neurons from a somatic cell by forced expression of transcription factors. The generated neurons can be used for both cell replacement strategies and disease modelling....
Healthy lifestyle and the risk of pancreatic cancer in the EPIC study.
Sabine Naudin, Vivian Viallon, Dana Hashim, Heinz Freisling, Mazda Jenab, Elisabete Weiderpass, Flavie Perrier, Fiona McKenzie, H Bas Bueno-De-Mesquita, Anja Olsen, Anne Tjønneland, Christina C Dahm, Kim Overvad, Francesca R Mancini, Vinciane Rebours, Marie-Christine Boutron-Ruault, Verena Katzke, Rudolf Kaaks, Manuela Bergmann, Heiner Boeing, Eleni Peppa, Anna Karakatsani, Antonia Trichopoulou, Valeria Pala, Giovana Masala, Salvatore Panico, Rosario Tumino, Carlotta Sacerdote, Anne M May, Carla H van Gils, Charlotta Rylander, Kristin Benjaminsen Borch, María Dolores Chirlaque López, Maria-Jose Sánchez, Eva Ardanaz, José Ramón Quirós, Pilar Amiano Exezarreta, Malin Sund, Isabel Drake, Sara Regnér, Ruth C Travis, Nick Wareham, Dagfinn Aune, Elio Riboli, Marc J Gunter, Eric J Duell, Paul Brennan, Pietro Ferrari
Oct 03, 2019
Pancreatic cancer (PC) is a highly fatal cancer with currently limited opportunities for early detection and effective treatment. Modifiable factors may offer pathways for primary prevention. In this study, the association...
Epic Healthy Lifestyle Index pancreatic cancer population attributable fraction prospective study Alcohol Drinking Cohort Studies Exercise Female Healthy lifestyle Humans Incidence Male Nutritional Status obesity obesity Abdominal Pancreatic Neoplasms Proportional Hazards Models Prospective Studies Risk Factors Smoking Waist-Hip Ratio
Reprogramming Human Adult Fibroblasts into GABAergic Interneurons.
Andreas Bruzelius, Srisaiyini Kidnapillai, Janelle Drouin-Ouellet, Tom Stoker, Roger A Barker, Daniella Rylander Ottosson
Jan 28, 2022
Direct reprogramming is an appealing strategy to generate neurons from a somatic cell by forced expression of transcription factors. The generated neurons can be used for both cell replacement strategies and disease modelling....
adult skin cells calbindin direct reprogramming disease-modelling Electrophysiology iN neuronal conversion Adult Brain Diseases Cell Differentiation Cellular Reprogramming Cognitive Dysfunction FIBROBLASTS GABAergic Neurons Gene Expression Regulation Humans Interneurons Neurogenesis Neuroglia Repressor Proteins Skin gamma-Aminobutyric Acid
Arbuscular cell invasion coincides with extracellular vesicles and membrane tubules.
Ronelle Roth, Stefan Hillmer, Charlotta Funaya, Marco Chiapello, Karin Schumacher, Libera Lo Presti, Regine Kahmann, Uta Paszkowski
May 29, 2020
Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain.
Marcella Birtele, Petter Storm, Yogita Sharma, Janko Kajtez, Jenny Nelander Wahlestedt, Edoardo Sozzi, Fredrik Nilsson, Simon Stott, Xiaoling L He, Bengt Mattsson, Daniella Rylander Ottosson, Roger A Barker, Alessandro Fiorenzano, Malin Parmar
Dec 12, 2022
Comparative validation of the BOADICEA and Tyrer-Cuzick breast cancer risk models incorporating classical risk factors and polygenic risk in a population-based prospective cohort of women of European ancestry
Parichoy Pal Choudhury, Mark N. Brook, Amber N. Hurson, Andrew Lee, Charlotta V. Mulder, Penny Coulson, Minouk J. Schoemaker, Michael E. Jones, Anthony J. Swerdlow, Nilanjan Chatterjee, Antonis C. Antoniou, Montserrat Garcia-Closas
Feb 16, 2021
Abstract: Background: The Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) and the Tyrer-Cuzick breast cancer risk prediction models are commonly used in clinical practice and have...
Age-related pathological impairments in directly reprogrammed dopaminergic neurons derived from patients with idiopathic Parkinson's disease.
Janelle Drouin-Ouellet, Emilie M Legault, Fredrik Nilsson, Karolina Pircs, Julie Bouquety, Florence Petit, Shelby Shrigley, Marcella Birtele, Maria Pereira, Petter Storm, Yogita Sharma, Andreas Bruzelius, Romina Vuono, Malin Kele, Thomas B Stoker, Daniella Rylander Ottosson, Anna Falk, Johan Jakobsson, Roger A Barker, Malin Parmar
Oct 24, 2022
We have developed an efficient approach to generate functional induced dopaminergic (DA) neurons from adult human dermal fibroblasts. When performing DA neuronal conversion of patient fibroblasts with idiopathic Parkinson's...
Comparative validation of the BOADICEA and Tyrer-Cuzick breast cancer risk models incorporating classical risk factors and polygenic risk in a population-based prospective cohort of women of European ancestry
Parichoy Pal Choudhury, Mark N. Brook, Amber N. Hurson, Andrew Lee, Charlotta V. Mulder, Penny Coulson, Minouk J. Schoemaker, Michael E. Jones, Anthony J. Swerdlow, Nilanjan Chatterjee, Antonis C. Antoniou, Montserrat Garcia-Closas
May 05, 2021
Abstract: Background: The Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) and the Tyrer-Cuzick breast cancer risk prediction models are commonly used in clinical practice and have...
Nutritional quality of food as represented by the FSAm-NPS nutrient profiling system underlying the Nutri-Score label and cancer risk in Europe
Mélanie Deschasaux, Inge Huybrechts, Neil Murphy, Chantal Julia, Serge Hercberg, Bernard Srour, Emmanuelle Kesse-Guyot, Paule Latino-Martel, Carine Biessy, Corinne Casagrande, Mazda Jenab, Heather Ward, Elisabete Weiderpass, Christina C Dahm, Kim Overvad, Cecilie Kyrø, Anja Olsen, Aurélie Affret, Marie-Christine Boutron-Ruault, Yahya Mahamat-Saleh, Rudolf Kaaks, Tilman Kühn, Heiner Boeing, Lukas Schwingshackl, Christina Bamia, Eleni Peppa, Antonia Trichopoulou, Giovanna Masala, Vittorio Krogh, Salvatore Panico, Rosario Tumino, Carlotta Sacerdote, Bas Bueno-de-Mesquita, Petra H Peeters, Anette Hjartåker, Charlotta Rylander, Guri Skeie, J Ramón Quirós, Paula Jakszyn, Elena Salamanca-Fernández, José María Huerta, Eva Ardanaz, Pilar Amiano, Ulrika Ericson, Emily Sonestedt, Ena Huseinovic, Ingegerd Johansson, Kay-Tee Khaw, Nick Wareham, Kathryn E Bradbury, Aurora Perez-Cornago, Konstantinos K Tsilidis, Pietro Ferrari, Elio Riboli, Marc J Gunter, Mathilde Touvier
Nov 21, 2018
BACKGROUND: Helping consumers make healthier food choices is a key issue for the prevention of cancer and other diseases. In many countries, political authorities are considering the implementation of a simplified labelling...
Plasma concentrations of persistent organic pollutants and pancreatic cancer risk.
Miquel Porta, Magda Gasull, José Pumarega, Hannu Kiviranta, Panu Rantakokko, Ole Raaschou-Nielsen, Ingvar A Bergdahl, Torkjel Manning Sandanger, Antoni Agudo, Charlotta Rylander, Therese Haugdahl Nøst, Carolina Donat-Vargas, Dagfinn Aune, Alicia K Heath, Lluís Cirera, Fernando Goñi-Irigoyen, Juan Alguacil, Àlex Giménez-Robert, Anne Tjønneland, Malin Sund, Kim Overvad, Francesca Romana Mancini, Vinciane Rebours, Marie-Christine Boutron-Ruault, Rudolf Kaaks, Matthias B Schulze, Antonia Trichopoulou, Domenico Palli, Sara Grioni, Rosario Tumino, Alessio Naccarati, Salvatore Panico, Roel Vermeulen, J Ramón Quirós, Miguel Rodríguez-Barranco, Sandra M Colorado-Yohar, María-Dolores Chirlaque, Eva Ardanaz, Nick Wareham, Tim Key, Mattias Johansson, Neil Murphy, Pietro Ferrari, Inge Huybrechts, Veronique Chajes, Carlos Alberto Gonzalez, Bas Bueno-de-Mesquita, Marc Gunter, Elisabete Weiderpass, Elio Riboli, Eric J Duell, Verena Katzke, Paolo Vineis
Jul 20, 2021
BACKGROUND: Findings and limitations of previous studies on persistent organic pollutants (POPs) and pancreatic cancer risk support conducting further research in prospective cohorts. METHODS: We conducted a prospective...
Heterogeneity of Associations between Total and Types of Fish Intake and the Incidence of Type 2 Diabetes
Silvia Pastorino, Tom Bishop, Stephen J Sharp, Matthew Pearce, Tasnime Akbaraly, Natalia B Barbieri, Maira Bes-Rastrollo, Joline WJ Beulens, Zhengming Chen, Huaidong Du, Bruce B Duncan, Atsushi Goto, Tommi Härkänen, Maryam Hashemian, Daan Kromhout, Ritva Järvinen, Mika Kivimaki, Paul Knekt, Xu Lin, Eiliv Lund, Dianna J Magliano, Reza Malekzadeh, Miguel Ángel Martínez-González, Gráinne O'Donoghue, Donal O'Gorman, Hossein Poustchi, Charlotta Rylander, Norie Sawada, Jonathan E Shaw, Maria Schmidt, Sabita S Soedamah-Muthu, Liang Sun, Wanqing Wen, Alicja Wolk, Xiao-Ou Shu, Wei Zheng, Nicholas J Wareham, Nita G Forouhi
Apr 19, 2021
The association between fish consumption and new-onset type 2 diabetes is inconsistent and differs according to geographical location. We examined the association between the total and types of fish consumption and type 2...
Heterogeneity of Associations between Total and Types of Fish Intake and the Incidence of Type 2 Diabetes
Silvia Pastorino, Tom Bishop, Stephen J. Sharp, Matthew Pearce, Tasnime Akbaraly, Natalia B. Barbieri, Maira Bes-Rastrollo, Joline W. J. Beulens, Zhengming Chen, Huaidong Du, Bruce B. Duncan, Atsushi Goto, Tommi Härkänen, Maryam Hashemian, Daan Kromhout, Ritva Järvinen, Mika Kivimaki, Paul Knekt, Xu Lin, Eiliv Lund, Dianna J. Magliano, Reza Malekzadeh, Miguel Ángel Martínez-González, Gráinne O’Donoghue, Donal O’Gorman, Hossein Poustchi, Charlotta Rylander, Norie Sawada, Jonathan E. Shaw, Maria Schmidt, Sabita S. Soedamah-Muthu, Liang Sun, Wanqing Wen, Alicja Wolk, Xiao-Ou Shu, Wei Zheng, Nicholas J. Wareham, Nita G. Forouhi
Apr 08, 2021
The association between fish consumption and new-onset type 2 diabetes is inconsistent and differs according to geographical location. We examined the association between the total and types of fish consumption and type 2...
REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways.
Janelle Drouin-Ouellet, Shong Lau, Per Ludvik Brattås, Daniella Rylander Ottosson, Karolina Pircs, Daniela A Grassi, Lucy M Collins, Romina Vuono, Annika Andersson Sjöland, Gunilla Westergren-Thorsson, Caroline Graff, Lennart Minthon, Håkan Toresson, Roger A Barker, Johan Jakobsson, Malin Parmar
Nov 27, 2017
Direct conversion of human fibroblasts into mature and functional neurons, termed induced neurons (iNs), was achieved for the first time 6 years ago. This technology offers a promising shortcut for obtaining patient- and...
Comparative validation of the BOADICEA and Tyrer-Cuzick breast cancer risk models incorporating classical risk factors and polygenic risk in a population-based prospective cohort of women of European ancestry.
Parichoy Pal Choudhury, Mark N Brook, Amber N Hurson, Andrew Lee, Charlotta V Mulder, Penny Coulson, Minouk J Schoemaker, Michael E Jones, Anthony J Swerdlow, Nilanjan Chatterjee, Antonis C Antoniou, Montserrat Garcia-Closas
Jan 28, 2021
BACKGROUND: The Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) and the Tyrer-Cuzick breast cancer risk prediction models are commonly used in clinical practice and have recently been...
Comparative validation of the BOADICEA and Tyrer-Cuzick breast cancer risk models incorporating classical risk factors and polygenic risk in a population-based prospective cohort of women of European ancestry
Parichoy Pal Choudhury, Mark N. Brook, Amber N. Hurson, Andrew Lee, Charlotta V. Mulder, Penny Coulson, Minouk J. Schoemaker, Michael E. Jones, Anthony J. Swerdlow, Nilanjan Chatterjee, Antonis C. Antoniou, Montserrat Garcia-Closas
Apr 13, 2021
Abstract: Background: The Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) and the Tyrer-Cuzick breast cancer risk prediction models are commonly used in clinical practice and have...
Regulome analysis in B-acute lymphoblastic leukemia exposes Core Binding Factor addiction as a therapeutic vulnerability.
Jason P Wray, Elitza M Deltcheva, Charlotta Boiers, Simon Е Richardson, Jyoti Bikram Chhetri, John Brown, Sladjana Gagrica, Yanping Guo, Anuradha Illendula, Joost HA Martens, Hendrik G Stunnenberg, John H Bushweller, Rachael Nimmo, Tariq Enver
Dec 22, 2022
Associations between maternal physical activity in early and late pregnancy and offspring birth size
Silvia Pastorino, Tom Bishop, Sarah R Crozier, Charlotta Granström, Katarzyna Kordas, Leanne K Küpers, Eileen O'Brien, Kinga Polanska, Katherine A Sauder, Mohammad Hadi Zafarmand, Becca Wilson, Charles Agyemang, Paul R Burton, Cyrus Cooper, Eva Corpeleijn, Dana Dabelea, Wojciech Hanke, Hazel M Inskip, Fionnuala McAuliffe, Sjurdur Frodi Olsen, Tanja G Vrijkotte, Soren Brage, Aileen Kennedy, Donal O'Gorman, Paul Scherer, Katrien Wijndaele, Nick J Wareham, Gernot Desoye, Ken K Ong
Nov 21, 2018
Demonstrating trustworthiness when collecting and sharing genomic data
Richard Milne, Katherine I Morley, Mohamed A Almarri, Shamim Anwer, Jerome Atutornu, Elena E Baranova, Paul Bevan, Maria Cerezo, Yali Cong, Alessia Costa, Christine Critchley, Josepine Fernow, Peter Goodhand, Qurratulain Hasan, Aiko Hibino, Gry Houeland, Heidi C Howard, S Zakir Hussain, Charlotta Ingvoldstad Malmgren, Vera L Izhevskaya, Aleksandra Jędrzejak, Cao Jinhong, Megumi Kimura, Erika Kleiderman, Brandi Leach, Keying Liu, Deborah Mascalzoni, Álvaro Mendes, Jusaku Minari, Dianne Nicol, Emilia Niemiec, Christine Patch, Jack Pollard, Barbara Prainsack, Marie Rivière, Lauren Robarts, Jonathan Roberts, Virginia Romano, Haytham A Sheerah, James Smith, Alexandra Soulier, Claire Steed, Vigdis Stefànsdóttir, Cornelia Tandre, Adrian Thorogood, Torsten H Voigt, Nan Wang, Anne V West, Go Yoshizawa, Anna Middleton
Jun 27, 2021
BACKGROUND: Public trust is central to the collection of genomic and health data and the sustainability of genomic research. To merit trust, those involved in collecting and sharing data need to demonstrate they are trustworthy....
Demonstrating trustworthiness when collecting and sharing genomic data
Richard Milne, Katherine I. Morley, Mohamed A. Almarri, Shamim Anwer, Jerome Atutornu, Elena E. Baranova, Paul Bevan, Maria Cerezo, Yali Cong, Alessia Costa, Christine Critchley, Josepine Fernow, Peter Goodhand, Qurratulain Hasan, Aiko Hibino, Gry Houeland, Heidi C. Howard, S. Zakir Hussain, Charlotta Ingvoldstad Malmgren, Vera L. Izhevskaya, Aleksandra Jędrzejak, Cao Jinhong, Megumi Kimura, Erika Kleiderman, Brandi Leach, Keying Liu, Deborah Mascalzoni, Álvaro Mendes, Jusaku Minari, Dianne Nicol, Emilia Niemiec, Christine Patch, Jack Pollard, Barbara Prainsack, Marie Rivière, Lauren Robarts, Jonathan Roberts, Virginia Romano, Haytham A. Sheerah, James Smith, Alexandra Soulier, Claire Steed, Vigdis Stefànsdóttir, Cornelia Tandre, Adrian Thorogood, Torsten H. Voigt, Nan Wang, Anne V. West, Go Yoshizawa, Anna Middleton
May 25, 2021
Abstract: Background: Public trust is central to the collection of genomic and health data and the sustainability of genomic research. To merit trust, those involved in collecting and sharing data need to demonstrate they are...
Sweet-beverage consumption and risk of pancreatic cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)
EM Navarrete-Muñoz, PA Wark, D Romaguera, N Bhoo-Pathy, D Michaud, E Molina-Montes, A Tjønneland, A Olsen, K Overvad, M-C Boutron-Ruault, F Clavel-Chapelon, G Fagherazzi, VA Katzke, T Kühn, A Steffen, A Trichopoulou, E Klinaki, E-M Papatesta, G Masala, V Krogh, R Tumino, A Naccarati, A Mattiello, PH Peeters, C Rylander, CL Parr, G Skeie, E Weiderpass, JR Quirós, EJ Duell, M Dorronsoro, JM Huerta, E Ardanaz, N Wareham, K-T Khaw, RC Travis, T Key, M Stepien, H Freisling, E Riboli, HB Bueno-De-Mesquita
Apr 07, 2017
Designing a broad-spectrum integrative approach for cancer prevention and treatment.
Keith I Block, Charlotte Gyllenhaal, Leroy Lowe, Amedeo Amedei, ARM Ruhul Amin, Amr Amin, Katia Aquilano, Jack Arbiser, Alexandra Arreola, Alla Arzumanyan, S Salman Ashraf, Asfar S Azmi, Fabian Benencia, Dipita Bhakta, Alan Bilsland, Anupam Bishayee, Stacy W Blain, Penny B Block, Chandra S Boosani, Thomas E Carey, Amancio Carnero, Marianeve Carotenuto, Stephanie C Casey, Mrinmay Chakrabarti, Rupesh Chaturvedi, Georgia Zhuo Chen, Helen Chen, Sophie Chen, Yi Charlie Chen, Beom K Choi, Maria Rosa Ciriolo, Helen M Coley, Andrew R Collins, Marisa Connell, Sarah Crawford, Colleen S Curran, Charlotta Dabrosin, Giovanna Damia, Santanu Dasgupta, Ralph J DeBerardinis, William K Decker, Punita Dhawan, Anna Mae E Diehl, Jin-Tang Dong, Q Ping Dou, Janice E Drew, Eyad Elkord, Bassel El-Rayes, Mark A Feitelson, Dean W Felsher, Lynnette R Ferguson, Carmela Fimognari, Gary L Firestone, Christian Frezza, Hiromasa Fujii, Mark M Fuster, Daniele Generali, Alexandros G Georgakilas, Frank Gieseler, Michael Gilbertson, Michelle F Green, Brendan Grue, Gunjan Guha, Dorota Halicka, William G Helferich, Petr Heneberg, Patricia Hentosh, Matthew D Hirschey, Lorne J Hofseth, Randall F Holcombe, Kanya Honoki, Hsue-Yin Hsu, Gloria S Huang, Lasse D Jensen, Wen G Jiang, Lee W Jones, Phillip A Karpowicz, W Nicol Keith, Sid P Kerkar, Gazala N Khan, Mahin Khatami, Young H Ko, Omer Kucuk, Rob J Kulathinal, Nagi B Kumar, Byoung S Kwon, Anne Le, Michael A Lea, Ho-Young Lee, Terry Lichtor, Liang-Tzung Lin, Jason W Locasale, Bal L Lokeshwar, Valter D Longo, Costas A Lyssiotis, Karen L MacKenzie, Meenakshi Malhotra, Maria Marino, Maria L Martinez-Chantar, Ander Matheu, Christopher Maxwell, Eoin McDonnell, Alan K Meeker, Mahya Mehrmohamadi, Kapil Mehta, Gregory A Michelotti, Ramzi M Mohammad, Sulma I Mohammed, D James Morre, Vinayak Muralidhar, Irfana Muqbil, Michael P Murphy, Ganji Purnachandra Nagaraju, Rita Nahta, Elena Niccolai, Somaira Nowsheen, Carolina Panis, Francesco Pantano, Virginia R Parslow, Graham Pawelec, Peter L Pedersen, Brad Poore, Deepak Poudyal, Satya Prakash, Mark Prince, Lizzia Raffaghello, Jeffrey C Rathmell, W Kimryn Rathmell, Swapan K Ray, Jörg Reichrath, Sarallah Rezazadeh, Domenico Ribatti, Luigi Ricciardiello, R Brooks Robey, Francis Rodier, HP Vasantha Rupasinghe, Gian Luigi Russo, Elizabeth P Ryan, Abbas K Samadi, Isidro Sanchez-Garcia, Andrew J Sanders, Daniele Santini, Malancha Sarkar, Tetsuro Sasada, Neeraj K Saxena, Rodney E Shackelford, HMC Shantha Kumara, Dipali Sharma, Dong M Shin, David Sidransky, Markus David Siegelin, Emanuela Signori, Neetu Singh, Sharanya Sivanand, Daniel Sliva, Carl Smythe, Carmela Spagnuolo, Diana M Stafforini, John Stagg, Pochi R Subbarayan, Tabetha Sundin, Wamidh H Talib, Sarah K Thompson, Phuoc T Tran, Hendrik Ungefroren, Matthew G Vander Heiden, Vasundara Venkateswaran, Dass S Vinay, Panagiotis J Vlachostergios, Zongwei Wang, Kathryn E Wellen, Richard L Whelan, Eddy S Yang, Huanjie Yang, Xujuan Yang, Paul Yaswen, Clement Yedjou, Xin Yin, Jiyue Zhu, Massimo Zollo
Feb 16, 2016
Exome-wide association study of plasma lipids in >300,000 individuals.
Dajiang J Liu, Gina M Peloso, Haojie Yu, Adam S Butterworth, Xiao Wang, Anubha Mahajan, Danish Saleheen, Connor Emdin, Dewan Alam, Alexessander Couto Alves, Philippe Amouyel, Emanuele Di Angelantonio, Dominique Arveiler, Themistocles L Assimes, Paul L Auer, Usman Baber, Christie M Ballantyne, Lia E Bang, Marianne Benn, Joshua C Bis, Michael Boehnke, Eric Boerwinkle, Jette Bork-Jensen, Erwin P Bottinger, Ivan Brandslund, Morris Brown, Fabio Busonero, Mark J Caulfield, John C Chambers, Daniel I Chasman, Y Eugene Chen, Yii-Der Ida Chen, Rajiv Chowdhury, Cramer Christensen, Audrey Y Chu, John M Connell, Francesco Cucca, L Adrienne Cupples, Scott M Damrauer, Gail Davies, Ian J Deary, George Dedoussis, Joshua C Denny, Anna Dominiczak, Marie-Pierre Dubé, Tapani Ebeling, Gudny Eiriksdottir, Tõnu Esko, Aliki-Eleni Farmaki, Mary F Feitosa, Marco Ferrario, Jean Ferrieres, Ian Ford, Myriam Fornage, Paul W Franks, Timothy M Frayling, Ruth Frikke-Schmidt, Lars G Fritsche, Philippe Frossard, Valentin Fuster, Santhi K Ganesh, Wei Gao, Melissa E Garcia, Christian Gieger, Franco Giulianini, Mark O Goodarzi, Harald Grallert, Niels Grarup, Leif Groop, Megan L Grove, Vilmundur Gudnason, Torben Hansen, Tamara B Harris, Caroline Hayward, Joel N Hirschhorn, Oddgeir L Holmen, Jennifer Huffman, Yong Huo, Kristian Hveem, Sehrish Jabeen, Anne U Jackson, Johanna Jakobsdottir, Marjo-Riitta Jarvelin, Gorm B Jensen, Marit E Jørgensen, J Wouter Jukema, Johanne M Justesen, Pia R Kamstrup, Stavroula Kanoni, Fredrik Karpe, Frank Kee, Amit V Khera, Derek Klarin, Heikki A Koistinen, Jaspal S Kooner, Charles Kooperberg, Kari Kuulasmaa, Johanna Kuusisto, Markku Laakso, Timo Lakka, Claudia Langenberg, Anne Langsted, Lenore J Launer, Torsten Lauritzen, David Cm Liewald, Li An Lin, Allan Linneberg, Ruth JF Loos, Yingchang Lu, Xiangfeng Lu, Reedik Mägi, Anders Malarstig, Ani Manichaikul, Alisa K Manning, Pekka Mäntyselkä, Eirini Marouli, Nicholas GD Masca, Andrea Maschio, James B Meigs, Olle Melander, Andres Metspalu, Andrew P Morris, Alanna C Morrison, Antonella Mulas, Martina Müller-Nurasyid, Patricia B Munroe, Matt J Neville, Jonas B Nielsen, Sune F Nielsen, Børge G Nordestgaard, Jose M Ordovas, Roxana Mehran, Christoper J O'Donnell, Marju Orho-Melander, Cliona M Molony, Pieter Muntendam, Sandosh Padmanabhan, Colin NA Palmer, Dorota Pasko, Aniruddh P Patel, Oluf Pedersen, Markus Perola, Annette Peters, Charlotta Pisinger, Giorgio Pistis, Ozren Polasek, Neil Poulter, Bruce M Psaty, Daniel J Rader, Asif Rasheed, Rainer Rauramaa, Dermot F Reilly, Alex P Reiner, Frida Renström, Stephen S Rich, Paul M Ridker, John D Rioux, Neil R Robertson, Dan M Roden, Jerome I Rotter, Igor Rudan, Veikko Salomaa, Nilesh J Samani, Serena Sanna, Naveed Sattar, Ellen M Schmidt, Robert A Scott, Peter Sever, Raquel S Sevilla, Christian M Shaffer, Xueling Sim, Suthesh Sivapalaratnam, Kerrin S Small, Albert V Smith, Blair H Smith, Sangeetha Somayajula, Lorraine Southam, Timothy D Spector, Elizabeth K Speliotes, John M Starr, Kathleen E Stirrups, Nathan Stitziel, Konstantin Strauch, Heather M Stringham, Praveen Surendran, Hayato Tada, Alan R Tall, Hua Tang, Jean-Claude Tardif, Kent D Taylor, Stella Trompet, Philip S Tsao, Jaakko Tuomilehto, Anne Tybjaerg-Hansen, Natalie R Van Zuydam, Anette Varbo, Tibor V Varga, Jarmo Virtamo, Melanie Waldenberger, Nan Wang, Nick J Wareham, Helen R Warren, Peter E Weeke, Joshua Weinstock, Jennifer Wessel, James G Wilson, Peter WF Wilson, Ming Xu, Hanieh Yaghootkar, Robin Young, Eleftheria Zeggini, He Zhang, Neil S Zheng, Weihua Zhang, Yan Zhang, Wei Zhou, Yanhua Zhou, Magdalena Zoledziewska, Charge Diabetes Working Group, EPIC-InterAct Consortium, EPIC-CVD Consortium, GOLD Consortium, VA Million Veteran Program, Joanna MM Howson, John Danesh, Mark I McCarthy, Chad A Cowan, Goncalo Abecasis, Panos Deloukas, Kiran Musunuru, Cristen J Willer, Sekar Kathiresan
May 21, 2018
We screened variants on an exome-focused genotyping array in >300,000 participants (replication in >280,000 participants) and identified 444 independent variants in 250 loci significantly associated with total cholesterol (TC)...
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.
Nicole M Warrington, Robin N Beaumont, Momoko Horikoshi, Felix R Day, Øyvind Helgeland, Charles Laurin, Jonas Bacelis, Shouneng Peng, Ke Hao, Bjarke Feenstra, Andrew R Wood, Anubha Mahajan, Jessica Tyrrell, Neil R Robertson, N William Rayner, Zhen Qiao, Gunn-Helen Moen, Marc Vaudel, Carmen J Marsit, Jia Chen, Michael Nodzenski, Theresia M Schnurr, Mohammad H Zafarmand, Jonathan P Bradfield, Niels Grarup, Marjolein N Kooijman, Ruifang Li-Gao, Frank Geller, Tarunveer S Ahluwalia, Lavinia Paternoster, Rico Rueedi, Ville Huikari, Jouke-Jan Hottenga, Leo-Pekka Lyytikäinen, Alana Cavadino, Sarah Metrustry, Diana L Cousminer, Ying Wu, Elisabeth Thiering, Carol A Wang, Christian T Have, Natalia Vilor-Tejedor, Peter K Joshi, Jodie N Painter, Ioanna Ntalla, Ronny Myhre, Niina Pitkänen, Elisabeth M van Leeuwen, Raimo Joro, Vasiliki Lagou, Rebecca C Richmond, Ana Espinosa, Sheila J Barton, Hazel M Inskip, John W Holloway, Loreto Santa-Marina, Xavier Estivill, Wei Ang, Julie A Marsh, Christoph Reichetzeder, Letizia Marullo, Berthold Hocher, Kathryn L Lunetta, Joanne M Murabito, Caroline L Relton, Manolis Kogevinas, Leda Chatzi, Catherine Allard, Luigi Bouchard, Marie-France Hivert, Ge Zhang, Louis J Muglia, Jani Heikkinen, EGG Consortium, Camilla S Morgen, Antoine HC van Kampen, Barbera DC van Schaik, Frank D Mentch, Claudia Langenberg, Jian'an Luan, Robert A Scott, Jing Hua Zhao, Gibran Hemani, Susan M Ring, Amanda J Bennett, Kyle J Gaulton, Juan Fernandez-Tajes, Natalie R Van Zuydam, Carolina Medina-Gomez, Hugoline G de Haan, Frits R Rosendaal, Zoltán Kutalik, Pedro Marques-Vidal, Shikta Das, Gonneke Willemsen, Hamdi Mbarek, Martina Müller-Nurasyid, Marie Standl, Emil VR Appel, Cilius E Fonvig, Caecilie Trier, Catharina EM van Beijsterveldt, Mario Murcia, Mariona Bustamante, Sílvia Bonas-Guarch, David M Hougaard, Josep M Mercader, Allan Linneberg, Katharina E Schraut, Penelope A Lind, Sarah E Medland, Beverley M Shields, Bridget A Knight, Jin-Fang Chai, Kalliope Panoutsopoulou, Meike Bartels, Friman Sánchez, Jakob Stokholm, David Torrents, Rebecca K Vinding, Sara M Willems, Mustafa Atalay, Bo L Chawes, Peter Kovacs, Inga Prokopenko, Marcus A Tuke, Hanieh Yaghootkar, Katherine S Ruth, Samuel E Jones, Po-Ru Loh, Anna Murray, Michael N Weedon, Anke Tönjes, Michael Stumvoll, Kim F Michaelsen, Aino-Maija Eloranta, Timo A Lakka, Cornelia M van Duijn, Wieland Kiess, Antje Körner, Harri Niinikoski, Katja Pahkala, Olli T Raitakari, Bo Jacobsson, Eleftheria Zeggini, George V Dedoussis, Yik-Ying Teo, Seang-Mei Saw, Grant W Montgomery, Harry Campbell, James F Wilson, Tanja GM Vrijkotte, Martine Vrijheid, Eco JCN de Geus, M Geoffrey Hayes, Haja N Kadarmideen, Jens-Christian Holm, Lawrence J Beilin, Craig E Pennell, Joachim Heinrich, Linda S Adair, Judith B Borja, Karen L Mohlke, Johan G Eriksson, Elisabeth E Widén, Andrew T Hattersley, Tim D Spector, Mika Kähönen, Jorma S Viikari, Terho Lehtimäki, Dorret I Boomsma, Sylvain Sebert, Peter Vollenweider, Thorkild IA Sørensen, Hans Bisgaard, Klaus Bønnelykke, Jeffrey C Murray, Mads Melbye, Ellen A Nohr, Dennis O Mook-Kanamori, Fernando Rivadeneira, Albert Hofman, Janine F Felix, Vincent WV Jaddoe, Torben Hansen, Charlotta Pisinger, Allan A Vaag, Oluf Pedersen, André G Uitterlinden, Marjo-Riitta Järvelin, Christine Power, Elina Hyppönen, Denise M Scholtens, William L Lowe, George Davey Smith, Nicholas J Timpson, Andrew P Morris, Nicholas J Wareham, Hakon Hakonarson, Struan FA Grant, Timothy M Frayling, Debbie A Lawlor, Pål R Njølstad, Stefan Johansson, Ken K Ong, Mark I McCarthy, John RB Perry, David M Evans, Rachel M Freathy
Apr 12, 2019
Adult Birth Weight blood pressure Body Height Diabetes mellitus Type 2 Female Fetal Development Genetic Predisposition to Disease Genome-Wide Association Study Heart Diseases Humans Infant Newborn Male Maternal Inheritance Maternal-Fetal Exchange Metabolic Diseases Models Genetic Polymorphism Single Nucleotide Pregnancy Risk Factors