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Cover Image for Genome-wide DNA methylation and gene expression patterns reflect genetic ancestry and environmental differences across the Indonesian archipelago.

Genome-wide DNA methylation and gene expression patterns reflect genetic ancestry and environmental differences across the Indonesian archipelago.

Heini M Natri, Katalina S Bobowik, Pradiptajati Kusuma, Chelzie Crenna Darusallam, Guy S Jacobs, Georgi Hudjashov, J Stephen Lansing, Herawati Sudoyo, Nicholas E Banovich, Murray P Cox, Irene Gallego Romero

Jul 03, 2020

Indonesia is the world's fourth most populous country, host to striking levels of human diversity, regional patterns of admixture, and varying degrees of introgression from both Neanderthals and Denisovans. However, it has been...

CpG Islands DNA Methylation Environment Epigenesis Genetic Ethnicity Gene Expression Profiling Gene-Environment Interaction Genetics Population Genome-Wide Association Study Genomics Humans Indonesia Islands Pacific Islands Pedigree Phenotype Polymorphism Single Nucleotide RNA-seq Transcriptome

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Multiple Deeply Divergent Denisovan Ancestries in Papuans

Guy S Jacobs, Georgi Hudjashov, Lauri Saag, Pradiptajati Kusuma, Chelzie C Darusallam, Daniel J Lawson, Mayukh Mondal, Luca Pagani, François-Xavier Ricaut, Mark Stoneking, Mait Metspalu, Herawati Sudoyo, J Stephen Lansing, Murray P Cox

Feb 17, 2020

Genome sequences are known for two archaic hominins—Neanderthals and Denisovans—which interbred with anatomically modern humans as they dispersed out of Africa. We identified high-confidence archaic haplotypes in 161 new...

Denisovan Indonesia Island Southeast Asia Neanderthal New Guinea archaic ancestry Animals Asian People Biological Evolution Gene Flow Genetic Introgression genetic variation Genome Human Haplotypes Hominidae Humans Indonesia Neanderthals Oceania

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