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Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein-Coupled Bile Acid Receptors.
Cheryl A Brighton, Juraj Rievaj, Rune E Kuhre, Leslie L Glass, Kristina Schoonjans, Jens J Holst, Fiona M Gribble, Frank Reimann
Aug 20, 2015
Animals Bile Acids and Salts Calcium Cells Cultured Cyclic AMP Enteroendocrine Cells Glucagon-Like Peptide 1 Intestine Small Intracellular Space Male Mice Knockout Mice Transgenic Microscopy Fluorescence Rats Wistar Receptors G-Protein-Coupled Taurodeoxycholic Acid Taurolithocholic Acid Tissue Culture Techniques
Psychology Professor Cheryl Fortner-Wood Elected New Chair of Faculty Conference
Winthrop University
Jan 01, 0001
Cheryl Fortner-Wood, associate professor of psychology, is the new chair of Faculty Conference. Fortner-Wood will begin her term, which expires in June 2009, in July.
Published by: Winthrop University
High fat diet impairs the function of glucagon-like peptide-1 producing L-cells.
Paul Richards, Ramona Pais, Abdella M Habib, Cheryl A Brighton, Giles SH Yeo, Frank Reimann, Fiona M Gribble
Jul 21, 2015
Inhibition of mitochondrial function by metformin increases glucose uptake, glycolysis and GDF-15 release from intestinal cells.
Ming Yang, Tamana Darwish, Pierre Larraufie, Debra Rimmington, Irene Cimino, Deborah A Goldspink, Benjamin Jenkins, Albert Koulman, Cheryl A Brighton, Marcella Ma, Brian YH Lam, Anthony P Coll, Stephen O'Rahilly, Frank Reimann, Fiona M Gribble
Jan 06, 2021
DACH1, a zona glomerulosa selective gene in the human adrenal, activates transforming growth factor-β signaling and suppresses aldosterone secretion.
Junhua Zhou, Lalarukh Haris Shaikh, Sudeshna G Neogi, Ian McFarlane, Wanfeng Zhao, Nichola Figg, Cheryl A Brighton, Carmela Maniero, Ada ED Teo, Elena AB Azizan, Morris J Brown
May 19, 2015
DACH1 protein Human aldosterone hyperaldosteronism Transforming Growth Factor beta zona glomerulosa Adrenocortical Carcinoma Aldosterone Disease Progression Eye Proteins Female Gene Expression Regulation Neoplastic Humans Immunohistochemistry Male Middle Aged RNA Neoplasm Real-Time Polymerase Chain Reaction Signal Transduction Transcription Factors Transforming Growth Factor beta Tumor Cells Cultured Zona Glomerulosa
Inhibition of mitochondrial function by metformin increases glucose uptake, glycolysis and GDF-15 release from intestinal cells
Relaxin/insulin-like family peptide receptor 4 (Rxfp4) expressing hypothalamic neurons modulate food intake and preference in mice.
Jo E Lewis, Orla RM Woodward, Danaé Nuzzaci, Christopher A Smith, Alice E Adriaenssens, Lawrence Billing, Cheryl Brighton, Benjamin U Phillips, John A Tadross, Sarah J Kinston, Ernesto Ciabatti, Berthold Göttgens, Marco Tripodi, David Hornigold, David Baker, Fiona M Gribble, Frank Reimann
Oct 21, 2022
OBJECTIVE: Insulin-like peptide 5 (INSL5) signalling, through its cognate receptor relaxin/insulin-like family peptide receptor 4 (RXFP4), has been reported to be orexigenic, and the high fat diet (HFD) preference observed in...
Using Electronic Gaming to Support Problem-Based Learning
Cheryl Blackmore
Sep 22, 2013
Published by: Technology-Mediated Learning
Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells.
Mohamed-Sami Trabelsi, Mehdi Daoudi, Janne Prawitt, Sarah Ducastel, Véronique Touche, Sama I Sayin, Alessia Perino, Cheryl A Brighton, Yasmine Sebti, Jérôme Kluza, Olivier Briand, Hélène Dehondt, Emmanuelle Vallez, Emilie Dorchies, Grégory Baud, Valeria Spinelli, Nathalie Hennuyer, Sandrine Caron, Kadiombo Bantubungi, Robert Caiazzo, Frank Reimann, Philippe Marchetti, Philippe Lefebvre, Fredrik Bäckhed, Fiona M Gribble, Kristina Schoonjans, François Pattou, Anne Tailleux, Bart Staels, Sophie Lestavel
Jan 31, 2020
Bile acids are signalling molecules, which activate the transmembrane receptor TGR5 and the nuclear receptor FXR. BA sequestrants (BAS) complex bile acids in the intestinal lumen and decrease intestinal FXR activity. The BAS-BA...
Animals Anticholesteremic Agents Basic Helix-Loop-Helix Leucine Zipper Transcription Factors Bile Acids and Salts Blood Glucose Colesevelam Hydrochloride Colon Diet High-Fat Enteroendocrine Cells Glucagon-Like Peptide 1 Glycolysis Humans Ileum Insulin Insulin Secretion Insulin-Secreting Cells Intestinal Mucosa Intestines Jejunum Mice Mice Knockout Mice Obese Nuclear Proteins obesity Proglucagon RNA Messenger Receptors Cytoplasmic and Nuclear Receptors G-Protein-Coupled Sequestering Agents Signal Transduction Transcription Factors
High-flow nasal oxygen vs. standard oxygen therapy for patients undergoing transcatheter aortic valve replacement with conscious sedation
S Scheuermann, A Tan, P Govender, M Mckie, J Pack, G Martinez, F Falter, S George, A A. Klein
Apr 14, 2023
Psychology Professor Selected for Kinard Teaching Award
Winthrop University
Jan 01, 0001
President Dan Mahony will present Cheryl Fortner-Wood with the 2017 James Pinckney Kinard and Lee Wicker Kinard Award for Excellence in Teaching during the 11 a.m. ceremony at the Winthrop Coliseum. The Kinard Award is given...
Published by: Winthrop University
Learning the Practice of Understanding Myself
Kenneth Melchin
Mar 16, 2022
Kenneth R. Melchin is Emeritus Professor in the Faculty of Theology and Director of the Lonergan Centre at Saint Paul University, Ottawa. He has authored numerous publications including Spiritualizing Politics without...
Published by: Memorial University of Newfoundland
Achieving robustness to aleatoric uncertainty with heteroscedastic Bayesian optimisation
Ryan-Rhys Griffiths, Alexander A Aldrick, Miguel Garcia-Ortegon, Vidhi Lalchand, Alpha A Lee
Nov 23, 2021
Abstract: Bayesian optimisation is a sample-efficient search methodology that holds great promise for accelerating drug and materials discovery programs. A frequently-overlooked modelling consideration in Bayesian optimisation...
Effectiveness of an online module
BACKGROUND: Climate change has significant implications for health, yet healthcare provision itself contributes significant greenhouse gas emission. Medical students need to be prepared to address impacts of the changing...
Quantum Control via a Genetic Algorithm of the Field Ionization Pathway of a Rydberg Electron
Vincent C. Gregoric, Xinyue Kang, Zhimin Cheryl Liu, Zoe A Rowley, Thomas J. Carroll, Michael W. Noel
Jan 01, 0001
Quantum control of the pathway along which a Rydberg electron field ionizes is experimentally and computationally demonstrated. Selective field ionization is typically done with a slowly rising electric field pulse. The (1/n*)4...
quantum control GA genetic algorithm Rydberg states DFI field ionization Stark Atomic, Molecular and Optical Physics Quantum physics
Published by: Ursinus College
Commencement on Dec. 15 Will Honor Graduates and Kinard Award Winner
Winthrop University
Jan 01, 0001
HIGHLIGHTS President Dan Mahony will present Carsten with the 2018 James Pinckney Kinard and Lee Wicker Kinard Award for Excellence in Teaching during the 11 a.m. ceremony at the Winthrop Coliseum. More than 285 undergraduates...
Published by: Winthrop University
Commencement Exercises for Undergraduates and Graduates Set for Dec. 16
Winthrop University
Jan 01, 0001
The speaker at the 11 a.m. ceremony will be Professor of English John Bird, Winthrop's 2017 Distinguished Professor. President Dan Mahony will preside at the event, where master's or specialist degrees will be awarded to around...
Published by: Winthrop University
Science Educators Will Be on Campus This Weekend Discussing Teaching Strategies
Winthrop University
Jan 01, 0001
Called "Connecting Core Concepts and Best Teaching Practices in Biochemistry and Molecular Biology," the workshop will help attendees develop new assessment tools for core concepts in biochemistry and molecular biology. ...
Published by: Winthrop University
Learning the Practice of Understanding Myself
Kenneth Melchin
Mar 16, 2022
Kenneth R. Melchin is Emeritus Professor in the Faculty of Theology and Director of the Lonergan Centre at Saint Paul University, Ottawa. He has authored numerous publications including Spiritualizing Politics without...
Published by: Memorial University of Newfoundland
A Model of Cloud Forensic Application With Assurance of Cloud Log
The key concepts of digital forensic investigation in cloud computing are examination and investigation. Cybercriminals target cloud-based web applications due to presence of vulnerabilities. Forensic investigation is a complex...
Published by: IGI Global Scientific Publishing
Depression amongst interns working in a tertiary care teaching Hospital in Maharashtra
Background: Internship is a crucial stage of medical school regarding student stress which can affect thepatient care negatively. Retrieving knowledge about presence of depression is therefore important in itself and iffound...
Published by: IJHS Medical Association
The State Route 520 Floating Bridge in Seattle, Washington
Cheryl L White
Apr 09, 2013
The four longest floating bridges in the world are located in Seattle, Washington on the North West Coast of the United States of America. At 2.3 km long and 35 m wide, the Evergreen Point Floating Bridge, also known as the...
Civil Engineering (ENGI 8751) (Case Study) (Civil) (Floating Bridge) (SR 520) (Concrete Pontoons) (Seattle, Washington) (Evergreen Point Bridge)
Published by: Memorial University of Newfoundland
Using Electronic Gaming to Support Problem-Based Learning
Cheryl Blackmore
Sep 22, 2013
Published by: Technology-Mediated Learning
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