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Twelve-month effects of everolimus on renal and lung function in lung transplantation
Filippo Patrucco, Elias Allara, Massimo Boffini, Mauro Rinaldi, Cristina Costa, Carlo Albera, Paolo Solidoro
Feb 26, 2021
BACKGROUND: Chronic lung allograft dysfunction (CLAD), a complication affecting the survival of lung transplanted patients, includes two clinical phenotypes: bronchiolitis obliterans syndrome (BOS) and restrictive allograft...
Autoantibodies against cytokines
Anti-cytokine autoantibodies may cause immunodeficiency and have been recently recognized as 'autoimmune phenocopies of primary immunodeficiencies' and are found in particular, but not exclusively in adult patients. By blocking...
Autoantibodies against cytokines
Abstract: Anti-cytokine autoantibodies may cause immunodeficiency and have been recently recognized as ‘autoimmune phenocopies of primary immunodeficiencies’ and are found in particular, but not exclusively in adult patients. By...
Performance Enhancement of the Unbalanced Text Classification Problem Through a Modified Chi Square-Based Feature Selection Technique
This paper proposes a modified chi square-based feature selection algorithm in conjunction with a random vector functional link network-based text classifier for improving the classification performance of multi-labeled text...
Published by: IGI Global Scientific Publishing
Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity.
Linh T Bui, Nichelle I Winters, Mei-I Chung, Chitra Joseph, Austin J Gutierrez, Arun C Habermann, Taylor S Adams, Jonas C Schupp, Sergio Poli, Lance M Peter, Chase J Taylor, Jessica B Blackburn, Bradley W Richmond, Andrew G Nicholson, Doris Rassl, William A Wallace, Ivan O Rosas, R Gisli Jenkins, Naftali Kaminski, Jonathan A Kropski, Nicholas E Banovich, Human Cell Atlas Lung Biological Network
Jul 28, 2021
Patients with chronic lung disease (CLD) have an increased risk for severe coronavirus disease-19 (COVID-19) and poor outcomes. Here, we analyze the transcriptomes of 611,398 single cells isolated from healthy and CLD lungs to...
UK Lung Cancer RCT Pilot Screening Trial
JK Field, SW Duffy, DR Baldwin, DK Whynes, A Devaraj, KE Brain, T Eisen, J Gosney, BA Green, JA Holemans, T Kavanagh, KM Kerr, M Ledson, KJ Lifford, FE McRonald, A Nair, RD Page, MKB Parmar, DM Rassl, RC Rintoul, NJ Screaton, NJ Wald, D Weller, PR Williamson, G Yadegarfar, DM Hansell
Sep 05, 2018
BACKGROUND: Lung cancer screening using low-dose CT (LDCT) was shown to reduce lung cancer mortality by 20% in the National Lung Screening Trial. METHODS: The pilot UK Lung Cancer Screening (UKLS) is a randomised controlled...
User's Segmentation on Continued Knowledge Management System Use in the Public Sector
Chi-Cheng Huang
Jan 01, 2020
Knowledge management systems (KMS) can help an organization support knowledge management activities and thereby increase organizational performance. This study extends the expectation-confirmation model for predicting mandatory...
Published by: IGI Global Scientific Publishing
Surfactant protein D is a causal risk factor for COPD
Ma'en Obeidat, Xuan Li, Stephen Burgess, Guohai Zhou, Nick Fishbane, Nadia N Hansel, Yohan Bossé, Philippe Joubert, Ke Hao, David C Nickle, Maarten van den Berge, Wim Timens, Michael H Cho, Brian D Hobbs, Kim de Jong, Marike Boezen, Rayjean J Hung, Nicholas Rafaels, Rasika Mathias, Ingo Ruczinski, Terri H Beaty, Kathleen C Barnes, Peter D Paré, Don D Sin, Lung eQTL Consortium, Lung Health Study International COPD Genetics Consortium
Jul 25, 2018
Surfactant protein D (SP-D) is produced primarily in the lung and is involved in regulating pulmonary surfactants, lipid homeostasis and innate immunity. Circulating SP-D levels in blood are associated with chronic obstructive...
Measurement of extravascular lung water to diagnose severe reperfusion lung injury following pulmonary endarterectomy
The measurement of extravascular lung water is a relatively new technology which has not yet been well validated as a clinically useful tool. We studied its utility in patients undergoing pulmonary endarterectomy as they...
Winthrop's Psi Chi Chapter Wins Southeastern Regional Chapter Award
Winthrop University
Jan 01, 0001
The award recognizes chapters that serve as role models and promote Psi Chi's purposes. This is the first time Winthrop's Psi Chi chapter has received the Southeastern Regional Award.
Published by: Winthrop University
Sequential screening for lung cancer in a high-risk group: randomised controlled trial: LungSEARCH
Stephen G Spiro, Pallav L Shah, Robert C Rintoul, Jeremy George, Samuel Janes, Matthew Callister, Marco Novelli, Penny Shaw, Gabrijela Kocjan, Chris Griffiths, Mary Falzon, Richard Booton, Nicholas Magee, Michael Peake, Paul Dhillon, Kishore Sridharan, Andrew G Nicholson, Simon Padley, Magali N Taylor, Asia Ahmed, Jack Allen, Yenting Ngai, Nyasha Chinyanganya, Victoria Ashford-Turner, Sarah Lewis, Dahmane Oukrif, Pamela Rabbitts, Nicholas Counsell, Allan Hackshaw
Feb 08, 2021
BACKGROUND: Low-dose computed tomography (LDCT) screening detects early-stage lung cancer and reduces mortality. We proposed a sequential approach targeted to a high-risk group as a potentially efficient screening strategy....
Adenocarcinoma of Lung Bronchoscopy Carcinoma Large Cell Carcinoma Non-Small-Cell Lung Carcinoma Small Cell Carcinoma Squamous Cell Cytological Techniques Early Detection of Cancer Female Humans Lung Neoplasms Male Middle Aged Neoplasm Staging Optical Imaging Pulmonary Disease Chronic Obstructive Risk Assessment Sensitivity and Specificity Sputum Tomography X-Ray Computed United Kingdom
Behavior Analysis of Customer Churn for a Customer Relationship System
This article describes how the bank industry in Taiwan must function in today's tough and fiercely competitive domestic credit card market and subdued global market. Banks are increasingly emphasizing the importance of retaining...
Published by: IGI Global Scientific Publishing
Metabolic rewiring in mutant Kras lung cancer.
Lung cancer is the leading cause of cancer-related death worldwide, reflecting an unfortunate combination of very high prevalence and low survival rates, as most cases are diagnosed at advanced stages when treatment efficacy is...
Winthrop's Psi Chi Advisor Wins 2010-11 Denmark Award
Winthrop University
Jan 01, 0001
Sleigh will receive her award plaque at the Psi Chi Award Ceremony in Washington, D.C., in early August. The associate professor of psychology came to Winthrop in 2003.
Published by: Winthrop University
Early respiratory diagnosis
INTRODUCTION: The National Health Service for England Long Term Plan identifies respiratory disease as one of its priority workstreams. To assist with earlier and more accurate diagnosis of lung disease they recommend...
Effect of Tai Chi Exercise on Healthcare and Quality of Life of Middle-Aged and Elderly Patients With Hypertension
Hypertension, as a cardiovascular and cerebrovascular disease, is endangering human life and health. To address this issue, this article conducted a study on the impact of Tai Chi exercise on middle-aged and elderly hypertensive...
Published by: IGI Global Scientific Publishing
Psychological Disturbances in Lung Cancer Patients
Introduction: Lung cancer may be conceptualized as a stressor with psychological, behavioral and biological components that can severely impact upon quality of life (QOL). Lung cancer patients generally experience decreased QOL...
Published by: IJHS Medical Association
Developmental mechanisms and adult stem cells for therapeutic lung regeneration.
Chronic degenerative lung diseases are essentially untreatable pathological conditions. By contrast, the healthy lung has numerous mechanisms that allow for rapid repair and restoration of function following minor acute...
Comparative performance of lung cancer risk models to define lung screening eligibility in the United Kingdom
Hilary A. Robbins, Karine Alcala, Anthony J. Swerdlow, Minouk J. Schoemaker, Nick Wareham, Ruth C. Travis, Philip A. J. Crosbie, Matthew Callister, David R. Baldwin, Rebecca Landy, Mattias Johansson
Aug 02, 2021
Abstract: Background: The National Health Service England (NHS) classifies individuals as eligible for lung cancer screening using two risk prediction models, PLCOm2012 and Liverpool Lung Project-v2 (LLPv2). However, no study...
Psychological Disturbances in Lung Cancer Patients
Introduction: Lung cancer may be conceptualized as a stressor with psychological, behavioral and biological components that can severely impact upon quality of life (QOL). Lung cancer patients generally experience decreased QOL...
Published by: IJHS Medical Association
Comparative performance of lung cancer risk models to define lung screening eligibility in the United Kingdom.
Hilary A Robbins, Karine Alcala, Anthony J Swerdlow, Minouk J Schoemaker, Nick Wareham, Ruth C Travis, Philip AJ Crosbie, Matthew Callister, David R Baldwin, Rebecca Landy, Mattias Johansson
May 03, 2021
BACKGROUND: The National Health Service England (NHS) classifies individuals as eligible for lung cancer screening using two risk prediction models, PLCOm2012 and Liverpool Lung Project-v2 (LLPv2). However, no study has compared...
Intestine in the lung
JMW Slack
Jun 01, 2004
The phenomenon of metaplasia, in which one tissue type is converted into another, is beginning to be explained in molecular terms. The transformation of lung to intestinal tissue has not previously been described, but it is now...
Endoplasmic reticulum stress in lung disease.
Stefan J Marciniak
Mar 26, 2018
Exposure to inhaled pollutants, including fine particulates and cigarette smoke is a major cause of lung disease in Europe. While it is established that inhaled pollutants have devastating effects on the genome, it is now...
Lung function and microbiota diversity in cystic fibrosis
Leah Cuthbertson, Alan W. Walker, Anna E. Oliver, Geraint B. Rogers, Damian W. Rivett, Thomas H. Hampton, Alix Ashare, J. Stuart Elborn, Anthony De Soyza, Mary P. Carroll, Lucas R. Hoffman, Clare Lanyon, Samuel M. Moskowitz, George A. O’Toole, Julian Parkhill, Paul J. Planet, Charlotte C. Teneback, Michael M. Tunney, Jonathan B. Zuckerman, Kenneth D. Bruce, Christopher J. van der Gast
Jun 06, 2020
Abstract: Background: Chronic infection and concomitant airway inflammation is the leading cause of morbidity and mortality for people living with cystic fibrosis (CF). Although chronic infection in CF is undeniably...
Assessment of Breathlessness in Lung Cancer
Jing-Yu Tan, Janelle Yorke, Amelie Harle, Jacky Smith, Fiona Blackhall, Mark Pilling, Alex Molassiotis
May 30, 2018
CONTEXT: The Dyspnea-12 (D-12) Questionnaire is a well-validated instrument in respiratory illnesses for breathlessness assessment, but its psychometric properties have not been tested in lung cancer. OBJECTIVE: To demonstrate...
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