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Suitcases, keys and handkerchiefs
This article examines the particular challenges that are associated with collecting and exhibiting objects to represent immigrant narratives. Everyday objects play a crucial role in migration history and curators need to...
Heritage-based tribalism in Big Data ecologies
This article presents a conceptual and methodological framework to study heritage-based tribalism in Big Data ecologies by combining approaches from the humanities, social and computing sciences. We use such a framework...
Dissociation between arithmetic relatedness and distance effects is modulated by task properties
Suitcases, keys and handkerchiefs
This article examines the particular challenges that are associated with collecting and exhibiting objects to represent immigrant narratives. Everyday objects play a crucial role in migration history and curators need to...
Effects of low-level laser therapy on impaired mobility in dogs with naturally occurring osteoarthritis.
BACKGROUND: Osteoarthritis is common in the aging dog and is associated with chronic pain and impaired mobility. The main objective of this study was to determine whether low-level laser therapy (LLLT) would increase physical...
Advances in Engineering Human Tissue Models.
Research in cell biology greatly relies on cell-based in vitro assays and models that facilitate the investigation and understanding of specific biological events and processes under different conditions. The quality of such...
Role of VHL, HIF1A and SDH on the expression of miR-210
A Merlo, C Bernardo-Castiñeira, I Sáenz-de-Santa-María, AS Pitiot, M Balbín, A Astudillo, N Valdés, B Scola, R Del Toro, S Mendez-Ferrer, JI Piruat, C Suarez, M-D Chiara
Aug 16, 2017
The hypoxia-inducible factor 1α (HIF-1α) and its microRNA target, miR-210, are candidate tumor-drivers of metabolic reprogramming in cancer. Neuroendocrine neoplasms such as paragangliomas (PGLs) are particularly appealing for...
Addictive behaviour in experimental animals
Since the introduction of intravenous drug self-administration methodology over 50 years ago, experimental investigation of addictive behaviour has delivered an enormous body of data on the neural, psychological and molecular...
On de Sitter string vacua from anti-d3-branes in the large volume scenario
Abstract
We consider de Sitter vacua realised in concrete type IIB Calabi-Yau compactifications with an anti D3-brane at the tip of a warped throat of...
Advances in Engineering Human Tissue Models
Research in cell biology greatly relies on cell-based in vitro assays and models that facilitate the investigation and understanding of specific biological events and processes under different conditions. The quality of such...
Compulsive Alcohol Seeking Results from a Failure to Disengage Dorsolateral Striatal Control over Behavior.
Lattice strain effects on doping, hydration and proton transport in scheelite-type electrolytes for solid oxide fuel cells
Lattice strain is considered a promising approach to modulate the structural and functional properties of oxide materials. In this study we investigate the effect of lattice strain on doping, hydration and proton transport...
An Observational Survey Study on the Use of Locoregional Anaesthesia in Non-Conventional Species
The objectives of this study were to investigate the current attitudes of veterinarians towards the use of locoregional anaesthesia in non-conventional animal species and to identify areas for future useful research on this...
Cerebral Autoregulation, Cerebral Hemodynamics, and Injury Biomarkers, in Patients with COVID-19 Treated with Veno-Venous Extracorporeal Membrane Oxygenation.
Małgorzata Burzyńska, Agnieszka Uryga, Magdalena Kasprowicz, Marek Czosnyka, Waldemar Goździk, Chiara Robba
Apr 17, 2023
BACKGROUND: This study aimed to describe the cerebrovascular dynamics, in particular cerebral autoregulation (CA), and cerebral biomarkers as neuron-specific enolase (NSE) in patients with a diagnosis of coronavirus disease 2019...
Embedding Recovery to Transform Inpatient Mental Health Care
OBJECTIVE: The 333 model is a radical redesign of acute mental health care. Time-limited inpatient pathways for assessment (≤3 days), treatment (≤3 weeks), and recovery (≤3 months) replaced traditional geographical-sector wards....
Misfolded protein oligomers induce an increase of intracellular Ca 2+ causing an escalation of reactive oxidative species
Giulia Fani, Chiara Ester La Torre, Roberta Cascella, Cristina Cecchi, Michele Vendruscolo, Fabrizio Chiti
Sep 15, 2022
Original Article NMDA receptors AMPA receptors Membrane destabilization Calcium homeostasis Oxidative Stress protein misfolding Neurodegenerative Diseases
Published by: Springer International Publishing
Misfolded protein oligomers induce an increase of intracellular Ca2+ causing an escalation of reactive oxidative species.
Giulia Fani, Chiara Ester La Torre, Roberta Cascella, Cristina Cecchi, Michele Vendruscolo, Fabrizio Chiti
Sep 27, 2022
Technology Emergence as a Structuring Process
Drawing on complexity theory, we investigate the structuring processes and underlying mechanisms underpinning the emergence of a new technology. Empirically, we track the emergence of blockchain technology by examining...
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