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Results: 431
DDX3X loss is an adverse prognostic marker in diffuse large B-cell lymphoma and is associated with chemoresistance in aggressive non-Hodgkin lymphoma subtypes.
Atish Kizhakeyil, Nurmahirah Binte Mohammed Zaini, Zhi Sheng Poh, Brandon Han Siang Wong, Xinpeng Loh, Aik Seng Ng, Zun Siong Low, Praseetha Prasannan, Chun Gong, Michelle Guet Khim Tan, Chandramouli Nagarajan, Dachuan Huang, Pang Wan Lu, Jing Quan Lim, Sharon Barrans, Choon Kiat Ong, Soon Thye Lim, Wee Joo Chng, George Follows, Daniel J Hodson, Ming Qing Du, Yeow Tee Goh, Suat Hoon Tan, Nicholas Francis Grigoropoulos, Navin Kumar Verma
Oct 22, 2021
DDX3X mutation Drug Resistance Hematolymphoid malignancy Prognosis Tumour metastasis Antineoplastic Agents Biomarkers Tumor Cell Line Tumor Cyclin D1 DEAD-box RNA Helicases Disease Progression Drug Resistance Neoplasm Humans Lymphoma Large B-Cell Diffuse Lymphoma Non-Hodgkin Mitogen-Activated Protein Kinases Mutation Prognosis STAT3 Transcription Factor Exome Sequencing
Rising within the leadership of an orthopaedic society
Gowreeson Thevendran, Mark Glazebrook, Deborah Eastwood, Kristy Weber, David Choon Siew Kit, Ashok Johari, Shanmuganathan Rajasekaran, Vikas Khanduja
Feb 04, 2022
Orthopaedic societies, with their diverse membership from across the world, serve a mission to endorse the progress and innovation in the field of orthopaedics and traumatology with a focus on improving patient care, as well as...
Refractory Lactic Acidosis and an Approach to its Management - A Case Report.
BACKGROUND: Lactic acidosis (LA) is a complication of diseases commonly seen in intensive care patients which carries an increased risk of mortality. It is classified by its pathophysiology; Type A results from tissue...
SIRS Triggered by Acute Right Ventricular Function, Mimicked Septic Shock.
BACKGROUND: The systemic inflammatory response syndrome (SIRS) is a complex immune response which can be precipitated by non-infectious aetiologies such as trauma, burns or pancreatitis. Addressing the underlying cause is...
Burnout and work-related stressors in gastroenterology
John Ong, Andrew Ming Liang Ong, Sharon Ong, Xiaohui Xin, Yeong Yeh Lee, Nonthalee Pausawasdi, Mark Anthony De Lusong, Dadang Makmun, Vui Heng Chong, Shiaw Hooi Ho, Wan Yen Lim, Calvin Jianyi Koh, David Ong, Christopher Khor, Yock Young Dan
Nov 09, 2020
BACKGROUND: Clinician burnout is an important occupational hazard that may be exacerbated by the novel COVID-19 pandemic. Within Southeast Asia, burnout in gastroenterology is understudied. The primary objective of this study is...
The impact of the coronavirus disease 2019 pandemic on gastroenterologists in Southeast Asia
John Ong, Andrew Ming Liang Ong, Sharon Ong, Xiaohui Xin, Yeong Yeh Lee, Nonthalee Pausawasdi, Mark Anthony De Lusong, Dadang Makmun, Vui Heng Chong, Shiaw Hooi Ho, Wanyen Lim, David Ong, Yock Young Dan, Christopher Khor
Jul 07, 2021
Service Evaluation of the Impact of Capnography on the Safety of Procedural Sedation.
Gareth Corbett, Peter Pugh, Jurgen Herre, Teik Choon See, David de Monteverde-Robb, Rafael Torrejon Torres, Rhodri Saunders, Catherine Leonard, Amit Prakash
May 20, 2022
Background: Capnography has been associated with a reduced incidence of events related to respiratory compromise during procedural sedation. Methods: A prospective service evaluation was conducted at a large United Kingdom (UK)...
Service Evaluation of the Impact of Capnography on the Safety of Procedural Sedation.
Gareth Corbett, Peter Pugh, Jurgen Herre, Teik Choon See, David de Monteverde-Robb, Rafael Torrejon Torres, Rhodri Saunders, Catherine Leonard, Amit Prakash
Aug 18, 2022
BACKGROUND: Capnography has been associated with a reduced incidence of events related to respiratory compromise during procedural sedation. METHODS: A prospective service evaluation was conducted at a large United Kingdom (UK)...
The Abbreviated Maslach Burnout Inventory Can Overestimate Burnout
Wan Yen Lim, John Ong, Sharon Ong, Ying Hao, Hairil Rizal Abdullah, Darren Lk Koh, Un Sam May Mok
Dec 27, 2019
The Maslach Burnout Inventory for healthcare professionals (MBI-HSS) and its abbreviated version (aMBI), are the most common tools to detect burnout in clinicians. A wide range in burnout prevalence is reported in...
Burnout in gastroenterology registrars
OBJECTIVE: The scale of burnout in UK gastroenterology trainees and the feasibility to determine its prevalence using the validated Maslach Burnout Inventory-Human Services Survey (MBI-HSS) tool are unknown. The primary...
health service research psychological stress Psychology Quality of life screening Achievement administrative personnel Adult awareness Burnout Professional Cross-Sectional Studies Depersonalization Emotions England Feasibility Studies Female Gastroenterology Humans Male Physicians prevalence Surveys and Questionnaires Workload
Bouveret Syndrome
John Ong, Carla Swift, Benjamin G Stokell, Sharon Ong, Pierino Lucarelli, Arun Shankar, Foad J Rouhani, Yasseen Al-Naeeb
Sep 09, 2021
BACKGROUND AND GOALS: Bouveret syndrome is characterized by gastroduodenal obstruction caused by an impacted gallstone. Current literature recommends endoscopic therapy as the first line of intervention despite significantly...
WHO Growth Standards – Suitable for Everyone? Yes
K Ong
Oct 02, 2017
Growth assessment and monitoring are cornerstones of paediatrics and child health. As critical as making accurate measurements are the availability of robust growth charts and the appropriate interpretation of percentiles to...
An Evaluation of the Performance of Five Burnout Screening Tools
Burnout is an important occupational hazard and early detection is paramount in preventing negative sequelae in physicians, patients, and healthcare systems. Several screening tools have been developed to replace lengthy...
The prevalence of burnout, risk factors, and job-related stressors in gastroenterologists
John Ong, Carla Swift, Michael Bath, Sharon Ong, Wanyen Lim, Yasseen Al-Naeeb, Arun Shankar, Yock Young Dan
Sep 10, 2021
Heterometallic Benzenehexathiolato Coordination Nanosheets
Ryojun Toyoda, Naoya Fukui, Dionisius HL Tjhe, Ekaterina Selezneva, Hiroaki Maeda, Cédric Bourgès, Choon Meng Tan, Kenji Takada, Yuanhui Sun, Ian Jacobs, Kazuhide Kamiya, Hiroyasu Masunaga, Takao Mori, Sono Sasaki, Henning Sirringhaus, Hiroshi Nishihara
Feb 21, 2022
Mentoring and Supervision in Academia
Dear Editor,
We read with interest the article entitled “Great Expectations: Principal Investigator and Trainee Perspectives on Hiring, Supervision, and Mentoring” by Kaps et al. We agree that a good mentor–mentee relationship...
Associations between Maternal Iron Supplementation in Pregnancy and Changes in Offspring Size at Birth Reflect Those of Multiple Micronutrient Supplementation.
It was previously observed that in a population of a high-income country, dietary multiple micronutrient supplementation in pregnancy was associated with an increased risk of gestational diabetes (GDM) and increased offspring...
Published by: Nutrients
Systematic review and meta-analysis of the association between childhood physical activity and age at menarche.
AIM: To systematically appraise and summarise published evidence on the association between childhood physical activity (PA) and subsequent age at menarche (AAM). METHODS: We searched PubMed (1990-2018) for studies that reported...
The association between mentoring and training outcomes in junior doctors in medicine
John Ong, Carla Swift, Nicholas Magill, Sharon Ong, Anne Day, Yasseen Al-Naeeb, Arun Shankar
Mar 18, 2020
OBJECTIVE: To determine quantitatively if a positive association exists between the mentoring of junior doctors and better training outcomes in postgraduate medical training within the UK. DESIGN: Observational study....
Developing a lifestyle intervention program for overweight or obese preconception, pregnant and postpartum women using qualitative methods.
Chee Wai Ku, Shu Hui Leow, Lay See Ong, Christina Erwin, Isabella Ong, Xiang Wen Ng, Jacinth JX Tan, Fabian Yap, Jerry Kok Yen Chan, See Ling Loy
Feb 15, 2022
The time period before, during and after pregnancy represents a unique opportunity for interventions to cultivate sustained healthy lifestyle behaviors to improve the metabolic health of mothers and their offspring. However, the...
Disease-associated XMRV sequences are consistent with laboratory contamination.
Stéphane Hué, Eleanor R Gray, Astrid Gall, Aris Katzourakis, Choon Ping Tan, Charlotte J Houldcroft, Stuart McLaren, Deenan Pillay, Andrew Futreal, Jeremy A Garson, Oliver G Pybus, Paul Kellam, Greg J Towers
Oct 03, 2018
BACKGROUND: Xenotropic murine leukaemia viruses (MLV-X) are endogenous gammaretroviruses that infect cells from many species, including humans. Xenotropic murine leukaemia virus-related virus (XMRV) is a retrovirus that has been...
Association of puberty timing with type 2 diabetes
Background: Emerging studies have investigated the association between puberty timing, particularly age at menarche (AAM), and type 2 diabetes. However, whether this association is independent of adiposity is unclear. We aimed...
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