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Results: 14998
Multidrug resistant enteric fever in South Asia
Christopher M Parry, Isabela Ribeiro, Kamini Walia, Priscilla Rupali, Stephen Baker, Buddha Basnyat
Apr 10, 2019
Investments in newer diagnostics and antimicrobial treatments are critical to improve management of enteric fever in South Asia, say Christopher Parry and colleagues
Computation Provides Chemical Insight into the Diverse Hydride NMR Chemical Shifts of [Ru(NHC)<sub>4</sub>(L)H]<sup>0/+</sup> Species (NHC = N-heterocyclic carbene; L = vacant, H<sub>2</sub>, N<sub>2</sub>, CO, MeCN, O<sub>2</sub>, P<sub>4</sub>, SO<sub>2</sub>, H<sup>-</sup>, F<sup>-</sup> and Cl<sup>-</sup>) and their [Ru(R<sub>2</sub>PCH<sub>2</sub>CH<sub>2</sub>PR<sub>2</sub>)<sub>2</sub>(L)H]<sup>+</sup> Congeners
L J L Haller, Elena Mas-Marza, Mateusz K Cybulski, Rajashekharayya A Sanguramath, Stuart A Macgregor, Mary F Mahon, Christophe Raynaud, Christopher A Russell, Michael K Whittlesey
Mar 07, 2017
Relativistic density functional theory calculations, both with and without the effects of spin–orbit coupling, have been employed to model hydride NMR chemical shifts for a series of [Ru(NHC)4(L)H]0/+ species (NHC =...
Poly (4-Vinylpyridine) Synthesis and Solution Properties
Warren L. Robinson, Jr.
Jan 01, 0001
This 28 page thesis reports the synthesis of poly (4-vinylpyridine) by cationic and free radical initiators, concentrated sulfuric acid and benzoylperoxide, respectively. The molecular weights of the various samples were...
Viscosity ionic strength Molecular Weight monomer purification cationic initiation free radical initiation Chemistry Physical Sciences and Mathematics
Published by: Ursinus College
Computation Provides Chemical Insight into the Diverse Hydride NMR Chemical Shifts of [Ru(NHC)<sub>4</sub>(L)H]<sup>0/+</sup> Species (NHC = N-heterocyclic carbene; L = vacant, H<sub>2</sub>, N<sub>2</sub>, CO, MeCN, O<sub>2</sub>, P<sub>4</sub>, SO<sub>2</sub>, H<sup>-</sup>, F<sup>-</sup> and Cl<sup>-</sup>) and their [Ru(R<sub>2</sub>PCH<sub>2</sub>CH<sub>2</sub>PR<sub>2</sub>)<sub>2</sub>(L)H]<sup>+</sup> Congeners
L J L Haller, Elena Mas-Marza, Mateusz K Cybulski, Rajashekharayya A Sanguramath, Stuart A Macgregor, Mary F Mahon, Christophe Raynaud, Christopher A Russell, Michael K Whittlesey
Mar 07, 2017
Relativistic density functional theory calculations, both with and without the effects of spin–orbit coupling, have been employed to model hydride NMR chemical shifts for a series of [Ru(NHC)4(L)H]0/+ species (NHC =...
Hydration and N-acetyl-l-cysteine alter the microstructure of human nail and bovine hoof
This work aimed to (a) characterize the microstructure and porosity of human nail and bovine hoof by mercury intrusion porosimetry and SEM image analysis, (b) study the effects of hydration and of N-acetyl-l-cysteine treatment...
Neurodevelopmental regression, severe generalized dystonia, and metabolic acidosis caused by POLR3A mutations.
Vanessa Zanette, Aurelio Reyes, Mark Johnson, Daniel do Valle, Alan J Robinson, Vaneisse Monteiro, Bruno Augusto Telles, Ricardo L R Souza, Mara L S F Santos, Cristiane Benincá, Massimo Zeviani
Nov 09, 2020
OBJECTIVE: To expand the clinical phenotype of POLR3A mutations by assessing the functional consequences of a missense and a splicing acceptor mutation. METHODS: We performed whole-exome sequencing for identification of likely...
Corinna PMG 655 (= P.Oxy. 2370) fr.1 l. 13 κόσμ[εισα λόγυ]ς
L Prauscello
May 02, 2017
0. Fr. 1 of P.Oxy. 2370 (= MP3
249; LDAB 573), published by Lobel in 1956, is so far the only papyrus
fragment among those extant in Boeotian dialect1
whose authorship can be securely ascribed to
Corinna thanks to the overlap...
Floer Simple Manifolds and L-Space Intervals
An oriented three-manifold with torus boundary admits either no L-space Dehn filling, a unique L-space filling, or an interval of L-space fillings. In the latter case, which we call “Floer simple,” we construct an invariant...
Hydration and N-acetyl-l-cysteine alter the microstructure of human nail and bovine hoof
This work aimed to (a) characterize the microstructure and porosity of human nail and bovine hoof by mercury intrusion porosimetry and SEM image analysis, (b) study the effects of hydration and of N-acetyl-l-cysteine treatment...
Eugene L. Opie, 1910
The Rockefeller University
Jan 01, 0001
Eugene L. Opie, M.D. Inflammation
Lecture delivered February 10th, 1910
Bacterial Infection inflammation reaction macrophage Lymphatic Vessels polynuclear leucocytes enzyme
Published by: J.B. Lippincott Company
L q -spectra of self-affine measures
Abstract: We study L q -spectra of planar self-affine measures generated by diagonal matrices. We introduce a new technique for constructing and understanding examples based on combinatorial estimates for the exponential growth...
S-2-Amino-4-cyanobutanoic acid (β-cyanomethyl-L-Ala) as an atom-efficient solubilising synthon for L-glutamine
Glutamine (Gln) is often a difficult amino acid to incorporate during solution-phase peptide synthesis, owing to poor solubility and unwanted dehydrations as side-reactions. Current approaches to solving these problems are...
L-Cell Expression of Melanocortin-4-Receptor Is Marginal in Most of the Small Intestine in Mice and Humans and Direct Stimulation of Small Intestinal Melanocortin-4-Receptors in Mice and Rats Does Not Affect GLP-1 Secretion
Rune E. Kuhre, Ida M. Modvig, Sara L. Jepsen, Hüsün S. Kizilkaya, Cecilie Bæch-Laursen, Christopher A. Smith, Frank Reimann, Fiona M. Gribble, Mette M. Rosenkilde, Jens J. Holst
Aug 19, 2021
The molecular sensors underlying nutrient-stimulated GLP-1 secretion are currently being investigated. Peripheral administration of melanocortin-4 receptor (MC4R) agonists have been reported to increase GLP-1 plasma...
L-Cell Expression of Melanocortin-4-Receptor Is Marginal in Most of the Small Intestine in Mice and Humans and Direct Stimulation of Small Intestinal Melanocortin-4-Receptors in Mice and Rats Does Not Affect GLP-1 Secretion.
Rune E Kuhre, Ida M Modvig, Sara L Jepsen, Hüsün S Kizilkaya, Cecilie Bæch-Laursen, Christopher A Smith, Frank Reimann, Fiona M Gribble, Mette M Rosenkilde, Jens J Holst
Sep 13, 2021
The molecular sensors underlying nutrient-stimulated GLP-1 secretion are currently being investigated. Peripheral administration of melanocortin-4 receptor (MC4R) agonists have been reported to increase GLP-1 plasma...
The use of third-party packed red blood cells during ex situ normothermic machine perfusion of organs for transplantation
Chris J Callaghan, Benedict L Phillips, Theodora Foukaneli, Susan Robinson, Christopher JE Watson
Oct 05, 2020
Ex situ normothermic machine perfusion (NMP) is being used increasingly in the assessment of higher risk deceased donor organs and to facilitate prolonged organ storage. Third-party packed red blood cells (pRBCs) are often used...
Frank L. Horsfall, Jr., 1952
The Rockefeller University
Jan 01, 0001
Frank L. Horsfall, Jr. Experiments on chemical alteration of virus infections.
Lecture delivered November 20, 1952
Posted with permission
Published by: Academic Press Inc., Publishers
L-Cell Expression of Melanocortin-4-Receptor Is Marginal in Most of the Small Intestine in Mice and Humans and Direct Stimulation of Small Intestinal Melanocortin-4-Receptors in Mice and Rats Does Not Affect GLP-1 Secretion.
Rune E Kuhre, Ida M Modvig, Sara L Jepsen, Hüsün S Kizilkaya, Cecilie Bæch-Laursen, Christopher A Smith, Frank Reimann, Fiona M Gribble, Mette M Rosenkilde, Jens J Holst
Sep 23, 2021
The molecular sensors underlying nutrient-stimulated GLP-1 secretion are currently being investigated. Peripheral administration of melanocortin-4 receptor (MC4R) agonists have been reported to increase GLP-1 plasma...
Published by: Frontiers in endocrinology
Rapid sensing of l-leucine by human and murine hypothalamic neurons
Nicholas Heeley, Peter Kirwan, Tamana Darwish, Marion Arnaud, Mark L Evans, Florian T Merkle, Frank Reimann, Fiona M Gribble, Clemence Blouet
Apr 05, 2018
OBJECTIVE: Dietary proteins are sensed by hypothalamic neurons and strongly influence multiple aspects of metabolic health, including appetite, weight gain, and adiposity. However, little is known about the mechanisms by which...
S-2-Amino-4-cyanobutanoic acid (β-cyanomethyl-L-Ala) as an atom-efficient solubilising synthon for L-glutamine
Glutamine (Gln) is often a difficult amino acid to incorporate during solution-phase peptide synthesis, owing to poor solubility and unwanted dehydrations as side-reactions. Current approaches to solving these problems are...
A structure determination protocol based on combined analysis of 3D-ED data, powder XRD data, solid-state NMR data and DFT-D calculations reveals the structure of a new polymorph of L-tyrosine
Christopher Smalley, Harriet Hoskynes, Colan Hughes, Duncan Johnstone, Tom Willhammer, Mark Young, Christopher Pickard, Andrew Logsdail, Paul Midgley, Kenneth Harris
Jul 03, 2022
We report the crystal structure of a new polymorph of L-tyrosine (denoted the β polymorph), prepared by crystallization from the gas phase following vacuum sublimation. Structure determination was carried out by combined...
Microbial regulation of the L cell transcriptome.
Tulika Arora, Rozita Akrami, Ramona Pais, Linda Bergqvist, Bengt R Johansson, Thue W Schwartz, Frank Reimann, Fiona M Gribble, Fredrik Bäckhed
Apr 26, 2018
L cells are an important class of enteroendocrine cells secreting hormones such as glucagon like peptide-1 and peptide YY that have several metabolic and physiological effects. The gut is home to trillions of bacteria affecting...
Dr. Herman L. Frick Promotion
Winthrop News Service
Jan 01, 0001
Dr. Herman L. Frick, superintendent of Winthrop Training School, was named Director of Teacher Education and Graduate Study at Winthrop in October 1946 Dr. Frick worked at Winthrop from 1941 to 1949 except for 1944-1946 when he...
Winthrop College of Education Winthrop Training School Higher Education Teacher Education and Professional Development
Published by: Winthrop University
Syncollin is an antibacterial polypeptide.
Syncollin is a 16-kDa protein found predominantly in the zymogen granules of pancreatic acinar cells, with expression at lower levels in intestinal epithelial cells and neutrophils. Here, we used Strep-tagged syncollin isolated...
Genes encoding ACE2, TMPRSS2 and related proteins mediating SARS-CoV-2 viral entry are upregulated with age in human cardiomyocytes.
Emma L Robinson, Kanar Alkass, Olaf Bergmann, Janet J Maguire, H Llewelyn Roderick, Anthony P Davenport
Aug 20, 2020
Age (>70 years), case fatality rate (CFR,10.2%) and coexisting conditions, particularly cardiovascular disease (CFR,10.5%) and hypertension (CFR,6.0%), are independent predictors of adverse outcome for 45,000 COVID-19 patients...
angiotensin apelin Bradykinin covid-19 Human cardiomyocytes RNA-sequencing SARS-CoV-2 aging Angiotensin-Converting Enzyme 2 Angiotensins apelin Betacoronavirus Bradykinin covid-19 Cathepsin B Cathepsin L Coronavirus Infections Humans Myocardium Myocytes Cardiac Pandemics Peptidyl-Dipeptidase A Pneumonia Viral SARS-CoV-2 Serine Endopeptidases Virus Attachment Virus Internalization
Analytical validation of new ELISAs for the quantitation of polyclonal free light chains and comparison to existing assays for healthy and patient samples
Jennifer L J Heaney, John Campbell, Margaret Goodall, Tim Plant, Meena Shemar, Christopher Hand, Mark T. Drayson
Mar 31, 2020
Background: Polyclonal FLCs can be used as a biomarker of inflammation and immune activation in a range of diseases. This study evaluated the performance of new FLC ELISAs (Seralite FLC ELISA) for the quantitation of...
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