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A hexa-species transcriptome atlas of mammalian embryogenesis delineates metabolic regulation across three different implantation modes
Abstract: Mammalian embryogenesis relies on glycolysis and oxidative phosphorylation to balance the generation of biomass with energy production. However, the dynamics of metabolic regulation in the postimplantation embryo in...
Multidrug resistant enteric fever in South Asia
Christopher M Parry, Isabela Ribeiro, Kamini Walia, Priscilla Rupali, Stephen Baker, Buddha Basnyat
Apr 10, 2019
Investments in newer diagnostics and antimicrobial treatments are critical to improve management of enteric fever in South Asia, say Christopher Parry and colleagues
A hexa-species transcriptome atlas of mammalian embryogenesis delineates metabolic regulation across three different implantation modes
Mammalian embryogenesis relies on glycolysis and oxidative phosphorylation to balance the generation of biomass with energy production. However, the dynamics of metabolic regulation in the postimplantation embryo in vivo have...
Microgel culture and spatial identity mapping elucidate the signalling requirements for primate epiblast and amnion formation.
Inferring the perturbation time from biological time course data.
MOTIVATION: Time course data are often used to study the changes to a biological process after perturbation. Statistical methods have been developed to determine whether such a perturbation induces changes over time, e.g....
Building a stem cell-based primate uterus.
Sophie Bergmann, Magdalena Schindler, Clara Munger, Christopher A Penfold, Thorsten E Boroviak
Jul 29, 2021
The uterus is the organ for embryo implantation and fetal development. Most current models of the uterus are centred around capturing its function during later stages of pregnancy to increase the survival in pre-term births....
A Comparative Analysis of Deep Learning Approaches for Network Intrusion Detection Systems (N-IDSs)
Recently, due to the advance and impressive results of deep learning techniques in the fields of image recognition, natural language processing and speech recognition for various long-standing artificial intelligence (AI) tasks...
Published by: IGI Global Scientific Publishing
Modeling meiotic chromosomes indicates a size dependent contribution of telomere clustering and chromosome rigidity to homologue juxtaposition.
Meiosis is the cell division that halves the genetic component of diploid cells to form gametes or spores. To achieve this, meiotic cells undergo a radical spatial reorganisation of chromosomes. This reorganisation is a...
Building a stem cell-based primate uterus
Sophie Bergmann, Magdalena Schindler, Clara Munger, Christopher A. Penfold, Thorsten E. Boroviak
Jun 17, 2021
Abstract: The uterus is the organ for embryo implantation and fetal development. Most current models of the uterus are centred around capturing its function during later stages of pregnancy to increase the survival in pre-term...
The neural basis of hot and cold cognition in depressed patients, unaffected relatives, and low-risk healthy controls
BACKGROUND: Modern cognitive neuropsychological models of depression posit that negatively biased emotional ("hot") processing confers risk for depression, while preserved executive function ("cold") cognition promotes...
Epigenetic resetting in the human germ line entails histone modification remodeling.
Wolfram H Gruhn, Walfred WC Tang, Sabine Dietmann, João P Alves-Lopes, Christopher A Penfold, Frederick CK Wong, Navin B Ramakrishna, M Azim Surani
Feb 19, 2023
Epigenetic resetting in the mammalian germ line entails acute DNA demethylation, which lays the foundation for gametogenesis, totipotency, and embryonic development. We characterize the epigenome of hypomethylated human...
Developmental programming by maternal obesity in 2015
Non-Lorentzian SU(1, n) Spacetime Symmetry In Various Dimensions
We discuss non-Lorentzian Lagrangian field theories in $2n-1$ dimensions that
admit an $SU(1,n)$ spacetime symmetry which includes a scaling transformation.
These can be obtained by a conformal compactification of a...
Diagnosing adult primary brain tumours
Clarissa Penfold is supported by funding from the Brain Tumour Charity (grant no. GN-000316).
The disruptive effects of pain on n-back task performance in a large general population sample
Abstract: Pain captures attention, displaces current concerns, and prioritises escape and repair. This attentional capture can be measured by its effects on general cognition. Studies on induced pain, naturally occurring acute...
The Arabidopsis thaliana N-recognin E3 ligase PROTEOLYSIS1 influences the immune response.
Christopher J Till, Jorge Vicente, Hongtao Zhang, Maria Oszvald, Michael J Deery, Victoria Pastor, Kathryn S Lilley, Rumiana V Ray, Frederica L Theodoulou, Michael J Holdsworth
Feb 24, 2020
N-degron pathways of ubiquitin-mediated proteolysis (formerly known as the N-end rule pathway) control the stability of substrate proteins dependent on the amino-terminal (Nt) residue. Unlike yeast or mammalian N-recognin E3...
The disruptive effects of pain on n-back task performance in a large general population sample
Abstract: Pain captures attention, displaces current concerns, and prioritises escape and repair. This attentional capture can be measured by its effects on general cognition. Studies on induced pain, naturally occurring acute...
The Arabidopsis thaliana N-recognin E3 ligase PROTEOLYSIS1 influences the immune response.
Christopher J Till, Jorge Vicente, Hongtao Zhang, Maria Oszvald, Michael J Deery, Victoria Pastor, Kathryn S Lilley, Rumiana V Ray, Frederica L Theodoulou, Michael J Holdsworth
Feb 02, 2020
N-degron pathways of ubiquitin-mediated proteolysis (formerly known as the N-end rule pathway) control the stability of substrate proteins dependent on the amino-terminal (Nt) residue. Unlike yeast or mammalian N-recognin E3...
Published by: Plant direct, volume 3, issue 12
Exact properties of an integrated correlator in N = 4 SU( N ) SYM
Abstract: We present a novel expression for an integrated correlation function of four superconformal primaries in SU(N) N = 4 supersymmetric Yang-Mills (N = 4 SYM) theory. This integrated correlator, which is based on...
Factorisation of 3d N = 4 twisted indices and the geometry of vortex moduli space
We study the twisted indices of $\mathcal{N}=4$ supersymmetric gauge theories
in three dimensions on spatial $S^{2}$ with an angular momentum refinement. We
demonstrate factorisation of the index into holomorphic blocks for...
Bottom-up growth of n-type monolayer molecular crystals on polymeric substrate for optoelectronic device applications.
Yanjun Shi, Lang Jiang, Jie Liu, Zeyi Tu, Yuanyuan Hu, Qinghe Wu, Yuanping Yi, Eliot Gann, Christopher R McNeill, Hongxiang Li, Wenping Hu, Daoben Zhu, Henning Sirringhaus
Nov 21, 2018
Self-assembly of monolayers of functional molecules on dielectric surfaces is a promising approach for the development of molecular devices proposed in the 1970s. Substrate chemically bonded self-assembled monolayers of...
HONORING TORSEN N. WIESEL
The Rockefeller University
Jan 01, 0001
A Celebration in Honor of Torsten N. Wiesel: Entering his Tenth Decade
Published by: The Rockefeller University
Voltammetric Monitoring of a Solid-Liquid Phase Transition in N,N,N’,N’-Tetraoctyl-2,6-diamino-9,10-anthraquinone (TODAQ)
Sun Yhik Ahn, Thomas Forder, Matthew Jones, Richard Blackburn, Paul Fordred, Steven Bull, Frank Marken
Jan 31, 2020
Exploratory experiments on effects from a phase transition are reported for a low-melting microcrystalline anthraquinone (N,N,N′,N′-tetraoctyl-2,6-diamino-9,10-anthraquinone or TODAQ). Data for the solid-liquid phase...
Battery materials Calorimetry Melting point Phase Transition Plastic crystalline solids Triple phase boundary Voltammetry /dk/atira/pure/subjectarea/asjc/2500/2500 name=General Materials Science /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/1600/1603 name=Electrochemistry /dk/atira/pure/subjectarea/asjc/2200/2208 name=Electrical and Electronic Engineering
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