Search
Results: 272
A disease-linked lncRNA mutation in RNase MRP inhibits ribosome synthesis.
Nic Robertson, Vadim Shchepachev, David Wright, Tomasz W Turowski, Christos Spanos, Aleksandra Helwak, Rose Zamoyska, David Tollervey
Mar 07, 2022
RMRP encodes a non-coding RNA forming the core of the RNase MRP ribonucleoprotein complex. Mutations cause Cartilage Hair Hypoplasia (CHH), characterized by skeletal abnormalities and impaired T cell activation. Yeast RNase MRP...
Animals Base Sequence Cell Proliferation Cells Cultured Endoribonucleases FIBROBLASTS Hair Hirschsprung Disease Humans K562 Cells Mice Inbred C57BL Mice Knockout Mutation Osteochondrodysplasias Primary Immunodeficiency Diseases RNA Folding RNA Precursors RNA Long Noncoding RNA Ribosomal Ribosomes T-Lymphocytes
Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation.
Abdulrahim A Sajini, Nila Roy Choudhury, Rebecca E Wagner, Susanne Bornelöv, Tommaso Selmi, Christos Spanos, Sabine Dietmann, Juri Rappsilber, Gracjan Michlewski, Michaela Frye
Apr 18, 2019
A disease-linked lncRNA mutation in RNase MRP inhibits ribosome synthesis.
Nic Robertson, Vadim Shchepachev, David Wright, Tomasz W Turowski, Christos Spanos, Aleksandra Helwak, Rose Zamoyska, David Tollervey
Feb 03, 2022
RMRP encodes a non-coding RNA forming the core of the RNase MRP ribonucleoprotein complex. Mutations cause Cartilage Hair Hypoplasia (CHH), characterized by skeletal abnormalities and impaired T cell activation. Yeast RNase MRP...
Student Engagement and Educational Benefits of Web GIS-Based Projects
The evolution of geographic information systems (GIS) based on the internet (Web GIS) created new opportunities for the use of GIS technology in education. In the present study a learning environment was developed which...
Published by: IGI Global Scientific Publishing
Effect of Base on the Facile Hydrothermal Preparation of Highly Active IrO<sub>x</sub> Oxygen Evolution Catalysts
Jonathan Ruiz Esquius, David J. Morgan, Ioannis Spanos, Daniel G. Hewes, Simon J. Freakley, Graham J. Hutchings
Jan 27, 2020
The efficient electrochemical splitting of water is limited by the anodic oxygen evolution reaction (OER). IrO2 is a potential catalyst with sufficient activity and stability in acidic conditions to be applied in...
amorphous iridium oxo-hydroxide Electrocatalysis hydrothermal synthesis iridium oxide Oxygen Evolution Reaction /dk/atira/pure/subjectarea/asjc/1500/1501 name=Chemical Engineering (miscellaneous) /dk/atira/pure/subjectarea/asjc/2100/2102 name=Energy Engineering and Power Technology /dk/atira/pure/subjectarea/asjc/1600/1603 name=Electrochemistry /dk/atira/pure/subjectarea/asjc/2500/2505 name=Materials Chemistry /dk/atira/pure/subjectarea/asjc/2200/2208 name=Electrical and Electronic Engineering
Preparation of Solid Solution and Layered IrO <sub>x</sub>-Ni(OH)<sub>2</sub>Oxygen Evolution Catalysts
Jonathan Ruiz Esquius, Gerardo Algara-Siller, Ioannis Spanos, Simon J. Freakley, Robert Schlögl, Graham J. Hutchings
Dec 18, 2020
Minimizing iridium loading in oxygen evolution reaction (OER) catalysts, without impairing electrocatalytic activity and stability is crucial to reduce the cost of water electrolysis. In this work, two Ir0.5Ni0.5Ox mixed...
Preparation of Solid Solution and Layered IrO <sub>x</sub>-Ni(OH)<sub>2</sub>Oxygen Evolution Catalysts
Jonathan Ruiz Esquius, Gerardo Algara-Siller, Ioannis Spanos, Simon J. Freakley, Robert Schlögl, Graham J. Hutchings
Dec 18, 2020
Minimizing iridium loading in oxygen evolution reaction (OER) catalysts, without impairing electrocatalytic activity and stability is crucial to reduce the cost of water electrolysis. In this work, two Ir0.5Ni0.5Ox mixed...
Effect of Base on the Facile Hydrothermal Preparation of Highly Active IrO<sub>x</sub> Oxygen Evolution Catalysts
Jonathan Ruiz Esquius, David J. Morgan, Ioannis Spanos, Daniel G. Hewes, Simon J. Freakley, Graham J. Hutchings
Jan 27, 2020
The efficient electrochemical splitting of water is limited by the anodic oxygen evolution reaction (OER). IrO2 is a potential catalyst with sufficient activity and stability in acidic conditions to be applied in...
amorphous iridium oxo-hydroxide Electrocatalysis hydrothermal synthesis iridium oxide Oxygen Evolution Reaction /dk/atira/pure/subjectarea/asjc/1500/1501 name=Chemical Engineering (miscellaneous) /dk/atira/pure/subjectarea/asjc/2100/2102 name=Energy Engineering and Power Technology /dk/atira/pure/subjectarea/asjc/1600/1603 name=Electrochemistry /dk/atira/pure/subjectarea/asjc/2500/2505 name=Materials Chemistry /dk/atira/pure/subjectarea/asjc/2200/2208 name=Electrical and Electronic Engineering
Setting up a rapid diagnostic clinic for patients with vague symptoms of cancer
Background
The study sought to evaluate the impact of a Rapid Diagnostic Clinic (RDC) service designed to improve general practitioner (GP) referral processes for patients who do not meet existing referral criteria yet...
The study sought to evaluate the impact of a Rapid Diagnostic Clinic (RDC) service designed to improve general practitioner (GP) referral processes for patients who do not meet existing referral criteria yet...
The efficiency of multivariate macroeconomic forecasts
We examine the efficiency of multivariate macroeconomic forecasts by estimating a vector autoregressive model on the forecast revisions of four variables (GDP, inflation, unemployment and wages). Using a data set of professional...
The efficiency of multivariate macroeconomic forecasts
We examine the efficiency of multivariate macroeconomic forecasts by estimating a vector autoregressive model on the forecast revisions of four variables (GDP, inflation, unemployment and wages). Using a data set of professional...
An Evaluation of the Effectiveness of Labor Market Integration Policies in EU Member States Using PROMETHEE
From an economic point of view, the rational response towards migration is the labor market integration of immigrants. Within the above framework, several actions have been developed by the European Union member states over the...
Published by: IGI Global Scientific Publishing
An Open Source Decision Support System for Facility Location Analysis
This paper introduces FLP Spreadsheet Solver, an open source spreadsheet based Decision Support System for Facility Location Problems. Structure of the spreadsheets, interface of the solver, and a Tabu Search algorithm...
Facility location analysis Health Services open source Spreadsheets /dk/atira/pure/subjectarea/asjc/1400/1404 name=Management Information Systems /dk/atira/pure/subjectarea/asjc/1700/1710 name=Information Systems /dk/atira/pure/subjectarea/asjc/3200/3204 name=Developmental and Educational Psychology /dk/atira/pure/subjectarea/asjc/1200/1201 name=Arts and Humanities (miscellaneous) /dk/atira/pure/subjectarea/asjc/1800/1802 name=Information Systems and Management
Busy academics share less
Although academics are increasingly expected to share their research data and materials with other academics, many appear reluctant to do so. While extant research emphasises commercial involvement and peer influence as...
Conclusion
Christos Lynteris
May 12, 2020
The Conclusion returns to the larger question of the role of ethnography in the development of plague science during the third pandemic. Discussing the challenges of rendering ethnographic data into epidemiological evidence...
Systems modelling and simulation in health service design, delivery and decision making
The ever increasing pressures to ensure the most efficient and effective use of limited health service resources will, over time, encourage policy makers to turn to system modelling solutions. Such techniques have been available...
Relativistic approach to the kinematics of large-scale peculiar motions
Abstract: We consider the linear kinematics of large-scale peculiar motions in a perturbed Friedmann universe. In so doing, we take the viewpoint of the “real” observers that move along with the peculiar flow, relative to the...
Neglecting Structural Breaks when Estimating and Valuing Dynamic Correlations for Asset Allocation
This paper assesses the econometric and economic value consequences of neglecting structural breaks in dynamic correlation models and in the context of asset allocation framework. It is shown that changes in the parameters of...
Photography and the Unseen
Drawing on works such as Shawn Michelle Smith’s At the Edge of Sight (2013), we explore the idea that photography, in supporting new kinds of seeing, even more importantly provokes expanded cultural concern with that which is...
The impact of increased outpatient telehealth during COVID-19
In response to societal restrictions due to the COVID-19 pandemic, a significant proportion of physical outpatient consultations were replaced with virtual appointments within the Bristol, North Somerset and South...
Managing the surge in demand for blood following mass casualty events. Early automatic restocking may preserve red cell supply
Background: Traumatic hemorrhage is a leading preventable cause of mortality following mass casualty events (MCEs). Improving outcomes requires adequate in-hospital provision of high volume red blood cell (RBC) transfusions....
Strategic management and regional industrial strategy
This study critically revisits extant perspectives and theories on strategic management (SM) and regional industrial strategy (RIS) and considers the scope for cross-fertilization to mutual advantage. Despite an extensive...
Innovation and Upheaval
The establishment and growth of the Greek stock market were coincident with development episodes, financial upheavals, and geographic expansions of the country's economy over the period 1880–1940. This article explores the...
|
|< |
< |
1 |