Recombinant human monoclonal HLA antibodies of different IgG subclasses recognising the same epitope
Cynthia SM Kramer,
Marry EI Franke-van Dijk,
Ashley J Priddey,
Tamás Pongrácz,
Elena Gnudi,
Helena Car,
Gonca E Karahan,
Els van Beelen,
Chalana CC Zilvold-van den Oever,
Hendrik J Rademaker,
Noortje de Haan,
Manfred Wuhrer,
Vasilis Kosmoliaptsis,
Paul WHI Parren,
Arend Mulder,
Dave L Roelen,
Frans HJ Claas,
Sebastiaan Heidt
Oct 29, 2019
In the field of transplantation, the humoural immune response against mismatched HLA antigens of the donor is associated with inferior graft survival, but not in every patient. Donor-specific HLA antibodies (DSA) of different...