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Results: 308
Effective induction therapy for anti-SRP associated myositis in childhood
E L Binns, Elena Moraitis, S Maillard, S Tansley, N McHugh, Thomas S Jacques, L R Wedderburn, Clarissa Pilkington, S A Yasin, Kiran Nistala
Oct 31, 2017
BACKGROUND: Anti-Signal Recognition Particle associated myopathy is a clinically and histopathologically distinct subgroup of Juvenile Idiopathic Inflammatory Myositis, which is under-recognised in children and fails to...
Anti-HMGCR Autoantibodies in Juvenile Idiopathic Inflammatory Myopathies Identify a Rare but Clinically Important Subset of Patients
Sarah L Tansley, Zoe E Betteridge, Stefania Simou, Thomas S Jacques, Clarissa Pilkington, Mark Wood, Kishore Warrier, Lucy R Wedderburn, Neil J McHugh
Apr 01, 2017
OBJECTIVE: We aimed to establish the prevalence and clinical associations of anti-HMG-CoA-reductase (anti-HMGCR) in a large UK cohort with juvenile myositis.
METHODS: There were 381 patients investigated for anti-HMGCR...
Effective induction therapy for anti-SRP associated myositis in childhood
E L Binns, Elena Moraitis, S Maillard, S Tansley, N McHugh, Thomas S Jacques, L R Wedderburn, Clarissa Pilkington, S A Yasin, Kiran Nistala
Oct 31, 2017
BACKGROUND: Anti-Signal Recognition Particle associated myopathy is a clinically and histopathologically distinct subgroup of Juvenile Idiopathic Inflammatory Myositis, which is under-recognised in children and fails to...
Anti-HMGCR Autoantibodies in Juvenile Idiopathic Inflammatory Myopathies Identify a Rare but Clinically Important Subset of Patients
Sarah L Tansley, Zoe E Betteridge, Stefania Simou, Thomas S Jacques, Clarissa Pilkington, Mark Wood, Kishore Warrier, Lucy R Wedderburn, Neil J McHugh
Apr 01, 2017
OBJECTIVE: We aimed to establish the prevalence and clinical associations of anti-HMG-CoA-reductase (anti-HMGCR) in a large UK cohort with juvenile myositis.
METHODS: There were 381 patients investigated for anti-HMGCR...
Diagnosing adult primary brain tumours
Clarissa Penfold is supported by funding from the Brain Tumour Charity (grant no. GN-000316).
Muscle biopsy in combination with myositis-specific autoantibodies aids prediction of outcomes in juvenile dermatomyositis
Claire T. Deakin, Shireena A. Yasin, Stefania Simou, Katie A. Arnold, Sarah L. Tansley, Zoe E. Betteridge, Neil J. McHugh, Hemlata Varsani, Janice L. Holton, Thomas S. Jacques, Clarissa A. Pilkington, Kiran Nistala, Lucy R. Wedderburn
Nov 01, 2016
Objective
Juvenile dermatomyositis (DM) is a rare and severe autoimmune condition characterized by rash and proximal muscle weakness. While some patients respond to standard treatment, others do not. This study was carried...
Juvenile dermatomyositis (DM) is a rare and severe autoimmune condition characterized by rash and proximal muscle weakness. While some patients respond to standard treatment, others do not. This study was carried...
Muscle biopsy in combination with myositis-specific autoantibodies aids prediction of outcomes in juvenile dermatomyositis
Claire T. Deakin, Shireena A. Yasin, Stefania Simou, Katie A. Arnold, Sarah L. Tansley, Zoe E. Betteridge, Neil J. McHugh, Hemlata Varsani, Janice L. Holton, Thomas S. Jacques, Clarissa A. Pilkington, Kiran Nistala, Lucy R. Wedderburn
Nov 01, 2016
Objective
Juvenile dermatomyositis (DM) is a rare and severe autoimmune condition characterized by rash and proximal muscle weakness. While some patients respond to standard treatment, others do not. This study was carried...
Juvenile dermatomyositis (DM) is a rare and severe autoimmune condition characterized by rash and proximal muscle weakness. While some patients respond to standard treatment, others do not. This study was carried...
Alternative Facts: Learning Only Happens in the Classroom
Just as learning occurs in the classroom, it also occurs out of the classroom. In Winthrop University's Department of Residence Life, professional and student staff instructs residential students in the "laboratory of life" with...
Retention academics Recruitment RECOGNITION Education Higher Education and Teaching Scholarship of Teaching and Learning
Published by: Winthrop University
The Effects of Price Regulation on Pharmaceutical R&D and Innovation
As rising health care expenditures focus government attention on slowing the growth, the pharmaceutical industry comes under increasing pressure to curb prices of ethical drugs. Pharmaceutical price regulations have been...
Japan drug exports patent protection profit regulation imitative Generics new molecular entities new chemical entities new biologic entities new active substances efficacy standards Clinical Trials mergers Business Economics Food and Drug Law Organizational Behavior and Theory Pharmacoeconomics and Pharmaceutical Economics
Published by: Ursinus College
Optimal influent N-to-P ratio for stable microalgal cultivation in water treatment and nutrient recovery
Dorottya Wagner, Clarissa Cazzaniga, Michael Steidl, Arnaud Dechesne, BOrja Valverde-Perez, Benedek Plosz
Jan 01, 2021
Species specific nitrogen-to-phosphorus molar ratio (NPR) has been suggested for green microalgae. Algae can store nitrogen and phosphorus, suggesting that the optimum feed concentration dynamically changes as function of the...
Trajectories of depression and generalised anxiety symptoms over the course of cognitive behaviour therapy in primary care
Background:
Cognitive-behavioural therapy (CBT) has been shown to be an effective treatment for depression and anxiety. However, most research has focused on the sum scores of symptoms. Relatively little is known about how...
Cognitive-behavioural therapy (CBT) has been shown to be an effective treatment for depression and anxiety. However, most research has focused on the sum scores of symptoms. Relatively little is known about how...
Clinical and laboratory phenotypes in juvenile-onset Systemic Lupus Erythematosus across ethnicities in the UK.
Joseph S Massias, Eve Md Smith, Eslam Al-Abadi, Kate Armon, Kathryn Bailey, Coziana Ciurtin, Joyce Davidson, Janet Gardner-Medwin, Kirsty Haslam, Dan P Hawley, Alice Leahy, Valentina Leone, Flora McErlane, Devesh Mewar, Gita Modgil, Robert Moots, Clarissa Pilkington, Athimalaipet V Ramanan, Satyapal Rangaraj, Phil Riley, Arani Sridhar, Nick Wilkinson, Michael W Beresford, Christian M Hedrich
Apr 10, 2021
Management Support Model for Information Technology Outsourcing
This study deals with the problem of outsourcing management, presenting a structure to support decision-making on effective information-technology outsourcing and highlighting the advantages and disadvantages that must be...
Published by: IGI Global Scientific Publishing
Optimal influent N-to-P ratio for stable microalgal cultivation in water treatment and nutrient recovery
Dorottya Wagner, Clarissa Cazzaniga, Michael Steidl, Arnaud Dechesne, BOrja Valverde-Perez, Benedek Plosz
Jan 01, 2021
Species specific nitrogen-to-phosphorus molar ratio (NPR) has been suggested for green microalgae. Algae can store nitrogen and phosphorus, suggesting that the optimum feed concentration dynamically changes as function of the...
Primary care use by men with symptoms of possible prostate cancer
OBJECTIVE: The objective of this study is to investigate primary care use by men with recent onset of lower urinary tract symptoms (LUTS) to identify differences in presentation and investigation that may explain ethnic...
Trajectories of depression and generalised anxiety symptoms over the course of cognitive behaviour therapy in primary care
Background:
Cognitive-behavioural therapy (CBT) has been shown to be an effective treatment for depression and anxiety. However, most research has focused on the sum scores of symptoms. Relatively little is known about how...
Cognitive-behavioural therapy (CBT) has been shown to be an effective treatment for depression and anxiety. However, most research has focused on the sum scores of symptoms. Relatively little is known about how...
We must look further upstream to enable planetary health-literate urban development
The gap between academic research and real-world practice in urban planning and development is a major barrier to planetary health.1 By exploring uncertainty and complexity further upstream, we might be able to narrow that gap...
Co-complex protein membership evaluation using Maximum Entropy on GO ontology and InterPro annotation.
Irina M Armean, Kathryn S Lilley, Matthew WB Trotter, Nicholas CV Pilkington, Sean B Holden
Feb 12, 2018
MOTIVATION: Protein-protein interactions (PPI) play a crucial role in our understanding of protein function and biological processes. The standardization and recording of experimental findings is increasingly stored in...
We must look further upstream to enable planetary health-literate urban development
The gap between academic research and real-world practice in urban planning and development is a major barrier to planetary health.1 By exploring uncertainty and complexity further upstream, we might be able to narrow that gap...
Precise identification of cancer cells from allelic imbalances in single cell transcriptomes.
Mi K Trinh, Clarissa N Pacyna, Gerda Kildisiute, Christine Thevanesan, Alice Piapi, Kirsty Ambridge, Nathaniel D Anderson, Eleonora Khabirova, Elena Prigmore, Karin Straathof, Sam Behjati, Matthew D Young
Oct 10, 2022
A fundamental step of tumour single cell mRNA analysis is separating cancer and non-cancer cells. We show that the common approach to separation, using shifts in average expression, can lead to erroneous biological conclusions....
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